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Hayeon Kim(Hayeon Kim),Bumhee Park(Bumhee Park),Shin-Young Kim(Shin-Young Kim),Jiyea Kim(Jiyea Kim),Bora Kim(Bora Kim),Kyu-In Jung(Kyu-In Jung),Seung-Yup Lee(Seung-Yup Lee),Yerin Hyun(Yerin Hyun),Bung 대한정신약물학회 2022 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.20 No.4
Objective: This research measures the regional GMV (rGMV) of the cerebellum, attention, Executive Function (EF) and we aimed to identify their correlation and sex differences in children and adolescents. Methods: Subjects comprised 114 children (male = 62, female = 52, 12.44 ± 2.99 years old) from South Korea. Participants were divided into three groups by age (age 6−9, 10−13, and 14−17). The Stroop Color and Word Test (SCWT), Wisconsin Card Sorting Test (WCST), and Advanced Test of Attention (ATA) were used to estimate executive function. Magnetic resonance imaging (MRI) images were analyzed with Regional Voxel-Based Morphometry Analysis. Results: The correlations between cerebellar rGMV and SCWT, WCST, and ATA subcategories showed difference by age and sex. In 6−9 age group, girls showed more overall correlations with cerebellar regions than boys, in WCST Categories Completed and ATA results. In age 10−13 group, more regions of cerebellum corresponded to SCWT subcategories in girls. Nevertheless, more correlation between cerebellar rGMV, WCST subcategories and some ATA subtests were observed in boys in the same age group. In the adolescent group, aged 14−17, boys showed more correlation with cerebellar rGMV, while girls showed little correlation. Conclusion: This study highlights that sex-different cerebellum maturation in adolescence might be correlated with EF and attention. These results provides evidence that cerebellum modulates higher cognitive functioning during child development.
Comorbidity of Narcolepsy and Obstructive Sleep Apnea: A Case Report
Hayeon Kim,Ji Hyun Song,Tae Won Kim,Sung Min Kim,엄유현,Ji Hye Oh,In Hee Cho,Seung Chul Hong 대한수면학회 2018 sleep medicine research Vol.9 No.2
Excessive daytime sleepiness (EDS) is the main symptom in narcoleptic patients. Obstructive sleep apnea (OSA) is known to be related to EDS. We describe three cases of narcolepsy that were misdi- agnosed as other diseases or as OSA alone. ree patients with the onset of snoring and daytime sleepiness in adolescence were referred to our sleep center. Polysomnography showed severe sleep apnea. eir multiple sleep latency test (MSLT) met the diagnostic criteria of narcolepsy. Another patient who had EDS and snoring showed severe OSA and positive results on MSLT. However, longitudinal clinical symptoms of this patient di ered from those of the three cases. EDS was ame- liorated in all four patients following the treatment with psychostimulants and the application of Continuous positive airway pressure. Patients su ering from EDS may be co-diagnosed with nar- colepsy and OSA. Clinicians should be aware of the possibility of false-positives of MSLT and the patient’s longitudinal clinical course.
Communicating Healthy Food Choice
Sang-Yeon Kim,Jennifer Morey Hawkins,Hayeon Song,Tae-Seop Lim,Emily McCarthy. Cramer,Seokhoon Ahn,Jihyun Kim,Hyun-Joo Kim,Junghyun Kim,Hiroshi Ota 한국언론학회 2016 Asian Communication Research Vol.13 No.1
This research examines cultural influence on the preference of promotive (i.e., trying to eat more healthy foods) and preventive (i.e., trying to avoid unhealthy foods) dietary practices. Survey data were collected from students and older adults in Korea (N = 287) and the U.S. (N = 245). Only students participated in the survey in Japan (N = 145). Consistent with the prediction, Study 1 shows Korean mature adults are more willing to adopt preventive dietary practices, while American counterparts favor promotive eating habits. The pattern of the data was inconsistent with the prediction among student participants across the three nations. Individual-level data from Study 2 (N = 284) confirm that independent self-construal affects promotive dietary practice via increasing promotive regulatory self-focus. The indirect impact of interdependent self-construal on preventive dietary practice was less apparent. Practical implications for doctor-patient communication are discussed.
Hayeon Jennifer Kim,이문수,양재원 연세대학교의과대학 2015 Yonsei medical journal Vol.56 No.5
Purpose: The aim of this study was to clarify the relationship between the autonomic nervous system and attention deficit hyperactivitydisorder (ADHD) rating scales and to evaluate the usefulness of heart rate variability (HRV) as a psychophysiological biomarkerfor ADHD. Materials and Methods: Subjects were recruited from outpatients in the Department of Child and Adolescent Psychiatry at the Korea University Medical Center from August 2007 to December 2010. Subjects received methylphenidate. Time- and frequency-domain analyses of HRV, the Korean ADHD rating scale (K-ARS), and computerized ADHD diagnostic system were evaluated beforetreatment. After a 12-week period of medication administration, we repeated the HRV measurements and K-ARS rating. Results: Eighty-six subjects were initially enrolled and 37 participants completed the 12-week treatment and HRV measurements subsequent to the treatment. Significant correlations were found between the K-ARS inattention score and some HRV parameters. All of the HRV parameters, except the standard deviations of the normal-to-normal interval, very low frequency, and low frequencyto high frequency, showed a significant positive correlation between baseline and endpoint measures in completers. High frequency (HF) and the square root of the mean squared differences of successive normal-to-normal intervals (RMSSD), which are related to parasympathetic vagal tone, showed significant decreases from baseline to endpoint. Conclusion: The HRV test was shown to be reproducible. The decrease in HF and RMSSD suggests that parasympathetic dominancein ADHD can be altered by methylphenidate treatment. It also shows the possibility that HRV parameters can be used as psychophysiological markers in the treatment of ADHD.
Disease risk prediction system using correlated health indexes
Kim, Yoonjung,Son, Hyeon Seok,Kim, Hayeon The Institute of Internet 2018 Journal of Advanced Smart Convergence Vol.7 No.4
With developments in science and technology and improvement in living standards, human life expectancy is steadily increasing worldwide. For effective healthcare, it is necessary to check health conditions according to individuals' behavior and acquire prior knowledge on possible diseases. In this study, we classified the diseases that are major causes of death in Korea by referring to data provided by the Korea National Health and Nutrition Examination Survey. We selected indexes that could be used as indicators of major diseases and created the LCBB-SC. In the LCBB-SC, the data are systematically subdivided into related fields to provide integrated data related to each disease and to provide an infrastructure that can be used by researchers. In addition, by developing a web interface allowing for self-symptom assessments, this resource will be beneficial to people who want to check their own health condition using a list of diseases that might be caused by their behaviors.
HCoV-IMDB: Database for the Analysis of Interactions between HCoV and Host Immune Proteins
Kim, Mi-Ran,Lee, Ji-Hae,Son, Hyeon Seok,Kim, Hayeon The Institute of Internet 2019 Journal of Advanced Smart Convergence Vol.8 No.1
Coronaviruses are known respiratory pathogens. In the past, most human coronaviruses were thought to cause mild symptoms such as cold. However recently, as seen in the Severe Acute Respiratory Syndrome (SARS) and the Middle East Respiratory Syndrome (MERS), infectious diseases with severe pulmonary disease and respiratory symptoms are caused by coronaviruses, making research on coronaviruses become important. Considering previous studies, we constructed 'HCoV-IMDB (Human Corona Virus Immune Database)' to systematically provide genetic information on human coronavirus and host immune information, which can be used to analyze the interaction between human coronavirus and host immune proteins. The 'HCoV-IMDB' constructed in the study can be used to search for genetic information on human coronavirus and host immune protein and to download data. A BLAST search specific to the human coronavirus, one of the database functions, can be used to infer genetic information and evolutionary relationship about the query sequence.