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( Sang Hoon Lee ),( Sang Hun Lee ),( Seung Up Kim ),( Beom Kyung Kim ),( Jun Yong Park ),( Do Young Kim ),( Sang Hoon Ahn ),( Kwang Hyub Han ) 대한간학회 2013 춘·추계 학술대회 (KASL) Vol.2013 No.1
Background/ Aims: Liver stiffness (LS) values measured using transient elastography (TE) can accurately assess the degree of liver fibrosis. The degree of liver fibrosis is significantly associated with the risk of hepatocellular carcinoma (HCC) development. Thus, this study investigated whether LS values at radiofrequency ablation (RFA) can predict HCC recurrence after RFA. Methods: Between May 2005 and April 2011, a total of 56 patients with HCC who underwent RFA and LS value measurement at the same day were analyzed in this retrospective study. All were followed up for monitoring the development of HCC recurrence until March 2013. Results: The mean age of the patients (40 men, 16 women) was 62.1 years, and the median LS value was 23.0 kPa. During the follow-up period (median 27.9 [range, 1.1-77.3] months), 33 (58.9%) patients experienced HCC recurrence and 18 (32.1%) were dead. Median time to recurrence was 17.1 (range, 2.5-67.8) months and median time to mortality was 27.9 (range, 1.1-77.3) months. Patients with recurrence showed significantly higher prevalence of liver cirrhosis, spleen size, multiple tumors, and LS values, whereas they had significantly lower platelet count than patients without recurrence (all P<0.05). On multivariate analysis, together with previous anti- HCC treatment history, patients with a higher LS value >13.0 kPa were at a significant greater risk for HCC recurrence after RFA with a hazard ratio of 6.981 (P<0.05; 95% confidence interval, 1.650-28.782) compared with those with LS value ≤13.0 kPa. However, LS values were not predictive for overall survival (P=0.237). Conclusions: Our data suggest that LS values measured using TE can be a useful predictor of HCC recurrence after RFA. Further studies with large sample size are warranted for the validation of our results.
( Han Ho Jeon ),( Yong Kang Lee ),( Dong Hyun Kim ),( Haeyong Pak ),( Sang Yun Shin ),( Jeong Hun Seo ) 대한내과학회 2021 The Korean Journal of Internal Medicine Vol.36 No.1
Background/Aims: To investigate whether visceral fat area (VFA) measured by bioelectric impedance analysis (BIA) was associated with metabolic syndrome in subjects with and without obesity. Methods: A total 23,202 participants who underwent medical check-ups were assessed. Participants were stratified by body mass index (BMI) and VFA. We evaluated six different groups for metabolic syndrome: Group 1 (normal weight and low VFA), Group 2 (normal weight and high VFA), Group 3 (overweight and low VFA), Group 4 (overweight and high VFA), Group 5 (obesity and low VFA), and Group 6 (obesity and high VFA). Results: Metabolic syndrome traits and metabolic syndrome were significantly more prevalent in the high-VFA (≥ 100 ㎠) subgroup in each BMI group. Adjusted logistic regression analyses revealed that the odds ratio for metabolic syndrome compared with Group 1 was the highest in Group 6 (24.53; 95% confidence interval [CI], 21.77 to 27.64). Notably, the odds ratio of Group 2 was higher than that of Group 3 (2.92; 95% CI, 2.30 to 3.69 vs. 2.57; 95% CI, 2.23 to 2.97). Conclusions: Our study demonstrates that the combination of BMI assessment and VFA determination by BIA may be a useful method for predicting the risk of metabolic syndrome. The VFA by BIA may be a useful target for interventions to improve metabolic syndrome.
( Han Sung Hwang ),( Sung Hun Na ),( Sung Eun Hur ),( Soon Ae Lee ),( Kyung A Lee ),( Geum Joon Cho ),( Kwan Young Oh ),( Chan Hee Jin ),( Seung Mi Lee ),( Jae Eun Shin ),( Kyo Hoon Park ),( Ji Young 대한산부인과학회 2015 Obstetrics & Gynecology Science Vol.58 No.3
Objective This study aimed to examine clinical practice patterns in the management of pregnant women admitted with threatened preterm labor (TPL) in Korea. Methods Data from women admitted with a diagnosis of TPL were collected from 22 hospitals. TPL was defined as regular uterine contractions with or without other symptoms such as pelvic pressure, backache, increased vaginal discharge, menstrual-like cramps, bleeding/show and cervical changes. Data on general patient information, clinical characteristics at admission, use of tocolytics, antibiotics, and corticosteroids, and pregnancy outcomes were collected using an online data collections system. Results A total of 947 women with TPL were enrolled. First-line tocolysis was administered to 822 (86.8%) patients. As a firstline tocolysis, beta-agonists were used most frequently (510/822, 62.0%), followed by magnesium sulfate (183/822, 22.3%), calcium channel blockers (91/822, 11.1%), and atosiban (38/822, 4.6%). Of the 822 women with first-line tocolysis, second-line tocolysis were required in 364 (44.3%). Of 364 with second-line, 199 had third-line tocolysis (37.4%). Antibiotics were administered to 29.9% of patients (284/947) with single (215, 22.7%), dual (26, 2.7%), and triple combinations (43, 4.5%). Corticosteroids were administered to 420 (44.4%) patients. Betamethasone was administered to 298 patients (71.0%), and dexamethasone was administered to 122 patients (29.0%). Conclusion Practice patterns in the management of TPL in Korea were quite various. It is needed to develop standardized practice guidelines for TPL management.
Han, Tae-Hee,Ko, Seok-Cheol,Lim, Sung-Hun Institute of Electrical and Electronics Engineers 2018 IEEE transactions on applied superconductivity Vol.28 No.4
<P>In this paper, the transformer type superconducting fault current limiter (SFCL) with two nonisolated secondary windings was suggested and its peak fault current limiting characteristics were analyzed. The suggested transformer type SFCL largely consists of two high-T<SUB>C</SUB> superconducting elements, one primary winding, and two nonisolated secondary windings, which are wound on the same iron core. Except for the structure with nonisolated secondary winding, the suggested transformer type SFCL has the similar operation to the previously reported transformer type SFCL with two triggering current levels. However, its peak fault current limiting characteristics are different from the previous transformer type SFCL. To confirm its peak fault current limiting operation with two limiting operational currents, the fault current limiting tests of the suggested SFCL according to the fault angle, which affects the amplitude of the initial transient fault current, were performed and its peak fault current limiting characteristics were discussed.</P>
A Study on Electro-optical Characteristics of the UV Aligned FFS Cell on the Organic Layer
Han, Jeong-Min,Ok, Chul-Ho,Hwang, Jeoung-Yeon,Kim, Byoung-Yong,Kang, Dong-Hun,Kim, Jong-Hwan,Kim, Young-Hwan,Han, Jin-Woo,Lee, Sang-Keuk,Seo, Dae-Shik The Korean Institute of Electrical and Electronic 2007 Transactions on Electrical and Electronic Material Vol.8 No.3
In this study, we investigated the electro-optical (EO) characteristic of fringe-field switching (FFS) mode cell by the two kinds of ultraviolet (UV) alignment method on the organic thin film (polyimide: PI). The suitable organic layers for FFS cell and the aligning capabilities of nematic liquid crystal (NLC) using the in-situ photoalignment method were studied; Disclination is observed after conventional photoalignment method for 1h, and in-situ photoalignment method for 1h. Monodomain alignment of the NLC can be observed via insitu photo alignment method for 2 h and 3 h. It is considered that NLC alignment is due to photo-depolymerization of the polymer with oblique non-polarized UV irradiation on PI surface. An unstable V-T curve of UV-aligned FFS-LCD with conventional photoalignment method can be achieved. However, a stable V-T curve of UV-aligned FFS-LCD with in-situ photoalignment method (1 h), and V-T curve of UV-aligned FFS-LCD with in-situ photo alignment method was much stable comparing with that of other UV-aligned FFSLCD's. As a result, more stable EO performance of UV-aligned FFS-LCD with in-situ photoalignment method for 3h is obtained than that of the other UV-aligned FFS-LCD's.