Systematic analysis of the pharmacological function of Schisandra as a potential exercise supplement

( Bok Sil Hong ),( Suji Baek ),( Myoung-ryu Kim ),( Sun Mi Park ),( Bom Sahn Kim ),( Jisu Kim ),( Kang Pa Lee ) 한국운동영양학회 2021 Physical Activity and Nutrition (Phys Act Nutr) Vol.25 No.4

[Purpose] Exercise can prevent conditions such as atrophy and degenerative brain diseases. However, owing to individual differences in athletic ability, exercise supplements can be used to improve a person’s exercise capacity. Schisandra chinensis (SC) is a natural product with various physiologically active effects. In this study, we analyzed SC using a pharmacological network and determined whether it could be used as an exercise supplement. [Methods] The active compounds of SC and target genes were identified using the Traditional Chinese Medicine Database and Analysis Platform (TCMSP). The active compound and target genes were selected based on pharmacokinetic (PK) conditions (oral bioavailability (OB) ≥ 30%, Caco-2 permeability (Caco-2) ≥ -0.4, and drug-likeness (DL) ≥ 0.18). Gene ontology (GO) was analyzed using the Cytoscape software. [Results] Eight active compounds were identified according to the PK conditions. Twenty-one target genes were identified after excluding duplicates in the eight active compounds. The top 10 GOs were analyzed using GO-biological process analysis. GO was subsequently divided into three representative categories: postsynaptic neurotransmitter receptor activity (53.85%), an intracellular steroid hormone receptor signaling pathway (36.46%), and endopeptidase activity (10%). SC is related to immune function. [Conclusion] According to the GO analysis, SC plays a role in immunity and inflammation, promotes liver metabolism, improves fatigue, and regulates the function of steroid receptors. Therefore, we suggest SC as an exercise supplement with nutritional and anti-fatigue benefits.

A systematic review of the biological mechanisms linking physical activity and breast cancer

( Bok Sil Hong ),( Kang Pa Lee ) 한국운동영양학회 2020 Physical Activity and Nutrition (Phys Act Nutr) Vol.24 No.3

[Purpose] Epidemiological evidence has shown that leisure-time physical activity and structured exercise before and after breast cancer diagnosis contribute to reducing the risk of breast cancer recurrence and mortality. Thus, in this review, we aimed to summarize the physical activity-dependent regulation of systemic factors to understand the biological and molecular mechanisms involved in the initiation, progression, and survival of breast cancer. [Methods] We systematically reviewed the studies on 1) the relationship between physical activity and the risk of breast cancer, and 2) various systemic factors induced by physical activity and exercise that are potentially linked to breast cancer outcomes. To perform this literature review, PubMed database was searched using the terms “Physical activity OR exercise” and “breast cancer”, until August 5th, 2020; then, we reviewed those articles related to biological mechanisms after examining the resulting search list. [Results] There is strong evidence that physical activity reduces the risk of breast cancer, and the protective effect of physical activity on breast cancer has been achieved by long-term regulation of various circulatory factors, such as sex hormones, metabolic hormones, inflammatory factors, adipokines, and myokines. In addition, physical activity substantially alters whole-body homeostasis by affecting numerous other factors, including plasma metabolites, reactive oxygen species, and microRNAs as well as exosomes and gut microbiota profile, and thereby every cell and organ in the whole body might be ultimately affected by the biological perturbation induced by physical activity and exercise. [Conclusion] The understanding of integrative mechanisms will enhance how physical activity can ultimately influence the risk and prognosis of various cancers, including breast cancer. Furthermore, physical activity could be considered an efficacious non-pharmacological therapy, and the promotion of physical activity is probably an effective strategy in primary cancer prevention.

장중첩증을 동반한 맹장 지방종 1예

홍의실,나병규,김민옥,유일영,채지영,채희복,윤세진,이상전,송형근,박길선,정현용 충남대학교 의과대학 의학연구소 2002 충남의대잡지 Vol.29 No.2

대장 지방종은 주로 우측 결장에 호발하고 특히 회맹판 부위와 맹장 부위에 호발한다. 또한 50~60대에 빈도가 높고 증상이 있는 환자에서 장중첩증이 높게는 40~50%에서 보고되고 있어 성인 장중첩증의 원인으로 중요한 비중을 차지한다. 특히 성인 장중첩증 및 장폐쇄의 중요 원인인 악성 종양과 임상 양상이 유사하여 감별진단이 중요하다. 저자들은 반복적인 복통을 주소로 내원한 환자에서 맹장의 4×5㎝의 점막하 지방종이 말단 회장부위와 반복적인 장중첩중이 발생했던 1례를 부분 절제술로 치료하여 양호한 임상 경과를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Lipomas are one of the most common benign nonepithelial tumors of the colon which are often detected incidentally by radiologic investigation or on operation. These tumors are usually without specific symptoms. Colonic lipomas occur most often in the right colon, particularly in the ileocecal valve and the cecum. Most patients are asymptomatic. but tumors larger than 2 cm tend to produce a change in bowel habit. abdominal pain. rectorrhagia and complications including luminal obstruction or intestinal intussusception. Diagnosis can be made by colonoscopy abdominal CT. MRI, or barium enema. We report a case of lipoma of the cecum that originated in the submucosa and presented as a intussusception in a 50-year-old woman with a brief review of the literature.

성인소비자의 소비자역량 유형별 소비관련 특성분석: 소비자역량의 구성요소에 따른 유형분류에 의하여

홍은실 ( Hong Eun-sil ),복미정 ( Bok Mi-Jung ) 한국소비자학회 2021 소비자학연구 Vol.32 No.5

본 연구는 성인소비자를 대상으로 하여 소비자역량의 구성요소인 지식과 태도, 실천 간의 구조적 특성을 파악하였고, 개인 소비자의 지식과 태도, 실천의 수준이 다를 수 있다는 전제로 소비자역량의 구성요소를 기준(특성)변인으로 하여 조사대상자들을 유형화하였다. 소비자역량의 구성요소에 따라 분류된 소비자유형별로 소비관련 전반적인 특성을 파악하여 소비자지식과 태도, 실천의 구조적 관계와 역할, 기능을 규명하였다. 연구 자료는 한국소비자원의 ‘2018 한국의 소비자역량지수’ 데이터에서 노년기 고유의 특성이 강한 60대 이상을 제외하고 20대~50대 소비자의 자료 1,481부를 사용하였다. 자료분석은 Ward의 계보적 군집분석, 일원분산분석, 던컨의 다중비교검증, 교차분석(χ²)을 실시하였다. 주요 연구결과는 다음과 같다. 첫째, 성인소비자의 소비자역량 구성요인 가운데 태도 점수가 가장 높고, 지식, 실천 순이어서 소비자역량을 구성하는데 태도의 역할이 컸다. 이러한 차이에도 불구하고 태도와 실천의 상관은 지식에 비해 매우 높았으며, 군집분석의 유형분류에서도 이러한 특성이 드러나 태도와 실천이 하나의 특성으로 반영되어 유형화되었다. 태도와 실천의 밀접한 관련성과 행동(실천)을 결정하는 요인으로서 태도의 중요성을 확인하였다. 둘째, 조사대상자를 소비자역량의 구성요인에 따라 여섯 집단 즉, 역량이 우수한 편인 3집단과 역량이 부족한 3집단으로 분류하였다. 소비자역량이 높은 순서대로 배열하면 ‘역량우수’ 집단, ‘태도·실천우수’ 집단, ‘지식우수’ 집단, ‘태도·실천부족’ 집단, ‘지식부족’ 집단, ‘역량부족’ 집단이며, 비율로 살펴보면 ‘지식우수’ 집단이 28.7%, ‘지식부족’ 집단이 22.9%로 가장 많으며, ‘역량우수’ 집단이 14.7%, ‘태도·실천우수’ 집단이 13%, ‘역량부족’ 집단이 12.4%, ‘태도·실천부족’ 집단이 8.4%를 차지하였다. 지식과 태도, 실천의 소비자역량이 모두 높은 집단을 소비자역량에서 이상적인 집단이라고 한다면 조사대상자의 85.3%는 소비자역량 강화를 위한 소비자교육이 필요하다고 할 수 있다. The purpose of this study is to present ways to improve consumption life conditions and strengthen consumer competencies in order to enhance consumer satisfaction. To this end, using the data of the Korea Consumer Agency's ‘2018 Consumer Empowerment Index in Korea’, adult consumer types were classified based on knowledge, attitudes, and practices of consumer competence, and consumption-related characteristics were analyzed. The collected 1,481 data were performed using SAS to analyze Pearson's correlation, cluster analysis of Wards, chisquare analysis, ANOVA, and Duncan’ multiple range test. Main results are as follows. First, among the components of consumer competence of adult consumers, consumer attitude scores were the highest, followed by knowledge and practice, indicating that attitudes play a greater role in constructing consumer competence and relatively less practice. Despite these differences, the correlation between attitudes and practices was very high compared to knowledge, and these characteristics were also revealed in the classification of cluster analyses, reflecting attitudes and practices as one characteristic. This confirms the importance of attitudes as a determinant of their close relevance and behavior. Second, The adult consumers surveyed were classified into six groups, namely three groups with superior capabilities and three groups with insufficient capabilities, according to the three components of consumer capabilities. Groups with superior capabilities explored consumer information a lot, evaluated financial status positively, was satisfied with consumer life, was confident as a consumer, and was well-equipped with consumer civic awareness and consumer protection legislation. Groups with insufficient capabilities had very low levels of consumer information exploration and have very negatively assessed financial status and satisfaction with consumer life, confidence and knowledge as consumers, consumer citizenship in our society, and the establishment of a consumer protection legal system.

A Study on Consumer Confidence, Satisfaction, and Repurchase Intention on Convenience Store Lunch Boxes by Food-related Lifestyle Type

Mi-Jung Bok(복미정),Eun-Sil Hong(홍은실) 한국컴퓨터정보학회 2022 韓國컴퓨터情報學會論文誌 Vol.27 No.3

본 연구는 편의점 도시락을 구매한 경험이 있는 소비자 488명을 대상으로 식생활 라이프스타일을 유형화 한 후 소비자신뢰, 만족도 및 재구매 의도를 분석하고자 하였다. 자료를 처리하기 위해 PASW 18.0 통계 프로그램을 이용하여, 빈도분석, k-평균 군집분석, 교차분석 및 일원분산분석을 실시하였다. 연구결과 첫째, 식생활 라이프스타일은 ‘외식추구형(11.7%)’, ‘편의추구형(18.3%)’, ‘음식무관심형(15%)’, ‘식생활관심형(55%)’ 등 4개의 집단으로 유형화되었다. 둘째, 식생활 라이프스타일 유형별 사회경제적 특성에서는 성별, 연령, 결혼여부, 교육수준, 월평균 가계소득, 월평균 용돈, 직업, 월평균 편의점 도시락 구입횟수, 도시락 구입 시간대 및 1회 평균 도시락 구입비용 등의 모든 변수에서 유의미한 차이가 나타났다. 셋째, 소비자신뢰에서는 편의추구형과 식생활관심형이, 만족도와 재구매 의도에서는 식생활관심형이 가장 높게 나타났다. This study was to analyze consumer confidence, satisfaction and repurchase intention after categorizing food-related lifestyle among 488 consumers who had experience purchasing convenience store lunch boxes. The data were analyzed with PASW 18.0 using frequency analysis, k-means cluster analysis, crosstabs analysis and one-way ANOVA. According to findings, first of all, types of food-related lifestyle are divided into 4 groups: a type of eating out(11.7%), a type of convenience seeking(18.3%), a type of food indifference(15%), a type of dietary interest(55%). Secondly, the types of food-related lifestyle showed statistically significant difference gender, age, marital status, education, monthly average household income, monthly average allowance, job, monthly average number of lunch box buying, lunch box purchase time zone and average one cost of lunch box buying of socio-economic variables. Thirdly, convenience seeking and dietary interest type showed the highest in consumer confidence and dietary interest type showed the highest level of satisfaction and repurchase intention.

A Study on the Impact of Emotional Labor of Sales and Service Workers

Mi-Jung Bok(복미정),Eun-Sil Hong(홍은실) 한국컴퓨터정보학회 2021 韓國컴퓨터情報學會論文誌 Vol.26 No.3

본 연구는 판매서비스직 종사자를 대상으로 감정노동이 미치는 영향을 분석하고자 하였다. 수집한 자료는 PASW 18.0 통계 프로그램을 이용하여 신뢰도분석, 빈도분석, T-test, one-way ANOVA, 상관관계분석, 다중회귀분석을 실시하였다. 연구결과 첫째, 판매서비스직 종사자들은 감정노동의 표면행동보다 내면행동이 더 높은 것으로 나타났다. 둘째, 이타주의는 근무경력에 따라, 양심행동은 성별에 따라, 직장-가정 갈등은 연령, 결혼여부, 1일 평균 고객 응대시간에 따라 차이가 있는 것으로 나타났다. 셋째, 감정노동의 표면행동이 높을수록 이타주의는 증가하였으며, 내면행동이 높을수록 직무소진과 직장-가정 갈등은 감소하였고, 이타주의와 양심행동은 증가하였다. 넷째, 감정노동과 관련된 변수들의 상대적 영향력을 분석한 결과 가장 크게 영향을 미치는 변수는 감정노동의 내면행동이었다. The purpose of this study is to analyze the impact about emotional labor of sales service workers. Collected data were statistically processed by PASW 18.0 program using reliability, frequency analysis, T-test, one-way ANOVA, correlation and multiple regression analysis. The results were as follows. First, it was found that the sales service workers had higher deep acting than the surface acting of emotional labor. Second, it was found that altruism differed according to working period, conscientiousness according to gender, and work-family conflict according to age, marital status, and average customer response time per day. Third, the higher the surface acting of emotional labor, the higher the altruism. And the higher the deep acting, the less job burnout and work-family conflict decreased, and the altruism and conscientiousness increased. Fourth, as a result of analyzing the relative influence of variables related to emotional labor, the variable that has the greatest influence was the deep acting of emotional labor.

연구논문 : 서비스 기업의 사회적 책임 활동이 기업이미지, 브랜드이미지, 구매의도에 미치는 영향

홍순복 ( Soon Bok Hong ),강경수 ( Kyoung Soo Kang ),이정실 ( Joung Sil Lee ),허범영 ( Beum Young Huh ) 대한관광경영학회 2012 觀光硏究 Vol.27 No.3

본 연구는 CJ푸드빌이 운영하는 ``VIPS``와 신세계그룹이 운영하는 ``웨스틴조선호텔``을 조사대상으로 선정하여 기업의 사회적책임활동이 기업이미지, 브랜드이미지, 구매의도에 어떠한 영향을 미치는지를 구조방정식 모형을 통해 검증하여 이론적 실무적 시사점을 제공하는데 연구목적이 있다. 연구모형을 토대로 독립변수의 사회적책임 요인은 경제적 책임, 법률적 책임, 윤리적 책임, 자선적 책임 요인으로 나누었고 매개변수는 기업이미지와 브랜드이미지를 종속변수는 구매의도를 사용하였다. 제시된 연구가설에 대한 실증분석의 결과, 첫째, 기업의 사회적 책임활동 중에서는 법률적 책임을 제외하고 경제적 책임, 윤리적 책임 그리고 자선적 책임이 기업의 이미지에 직접적으로 영향을 미치는 것으로 나타났다. 이는 경제적, 윤리적 그리고 자선적 책임은 기업의 이미지를 제고시키는데 많은 영향을 미치므로 다양하고 전략적으로 책임활동을 해야 함을 시사해주고 있다. 둘째, 기업의 사회적 책임활동 중 법률적 책임을 제외하고 경제적 책임, 윤리적 책임 그리고 자선적 책임이 브랜드 이미지에 직접적으로 영향을 미치는 것으로 나타났다. 특히 윤리적 책임활동은 기업 이미지뿐만 아니라 브랜드 이미지에도 가장 많은 영향을 미치는 것으로 나타났다. 셋째, 기업이미지가 구매의도에 직접적인 영향을 미치지 않는 것으로 나타났다. 이는 연구대상이 기업과 브랜드명이 완전히 달라 기업에 대한 이미지가 상대적으로 인식하지 못하고 있기 때문일 것이다. 넷째, 브랜드이미지는 구매의도에 직접적인 영향을 미치는 것으로 나타났다. 이는 구매의도를 높이기 위해서는 우선적으로 브랜드 이미지를 제고시킬 필요성이 있다는 것을 시사해준다. 따라서 다양한 브랜드 이미지를 제고시킬 수 있는 전략이 필요하다고 하겠다. This study aims to provide practical implications by analyzing the effects on corporate image, brand image and purchase intention of service companies` social responsibility, targeting ``VIPs`` run by CJ Foodvill and ``Western Chosun Hotel`` run by Shinsegae Group. The results of the analysis of this study show as follows: First, among social activities of corporate, economic responsibility, ethical responsibility and charitable responsibility except for legal liability has directly effects on corporate image. This indicates that corporations should do various responsible activities strategically since economic responsibility, ethical responsibility and charitable responsibility have many effects on improving corporate image. Second, economic responsibility, ethical responsibility and charitable responsibility except for legal liability among social activities of corporate have directly effects on corporate brand image. Especially they show that activities of ethical responsibility have many effects on brand image as well as corporate image. Third, corporate image does not have an effect on purchase intention directly. Maybe this is because relatively the corporate image isn`t re realized by consumers, since corporation and brand name as the objects of this study are different completely. Fourth, brand image has an effect on purchase intention directly. This indicates that corporations need to consider raising brand image first of all in order to raise consumers` purchase intention.

서비스 기업에서의 관계혜택이 관계몰입과 관계지속의도에 미치는 영향 -서비스 업종별 비교-

이정실 ( Joung Sil Lee ),허범영 ( Byum Young He ),홍순복 ( Soon Bok Hong ),임채관 ( Chae Kwan Lim ),강경수 ( Kyoung Soo Kang ),조윤주 ( Youn Joo Cho ) 관광경영학회 2012 관광경영연구 Vol.51 No.-

This study is to verify the structural relationship among 3 typical factor relational benefits, relational commitment, and relational continuance intention in service corporation. To test each measures; predictive utility in this context with AMOS. Sampling in this study is limited to the department store, beauty parlor, dental clinic and hotel restaurant in Busan, South Korea. The responders included 632. Data were analyzed by frequency, factor analysis, and AMOS. As the results, social benefit is major to influence on the relational commitment and relational continuance intention. Confidence benefit is major to influence on the relational continuance intention, while isn`t major determinant to influence on the relational commitment. Special treatment benefit is major to influence on the relational commitment, while isn`t major determinant to influence on the relational continuance intention. Social benefit is major to influence on the relational commitment in all of 4 service corporations. While confidence benefit isn`t major determinant to influence on the relational commitment in all of 4 service corporations. Special treatment benefits is major to influence on the relational commitment in beauty parlor, dental clinic and hotel restaurant.

지식적 심상 요법이 남자 고등학생의 스트레스, 스트레스 대처 및 건강문제에 미치는 영향

장순복 ( Soon Bok Chang ),김소야자 ( So Ya Ja Kim ),오가실 ( Ka Sil Oh ),유일영 ( Il Young Yoo ),김희순 ( Hee Soon Kim ),김선아 ( Sun Ah Kim ),김수 ( Sue Kim ),홍민순 ( Min Sun Hong ),배춘희 ( Choon Hee Bae ),김민정 ( Min Jeong Ki 한국정신간호학회 2007 정신간호학회지 Vol.16 No.1

Aging and Cancer : Sphingosine-1-phosphate is a Lymphangiogenic Lipid mediator

( Chang Min Yoon ),( Bok Sil Hong ),( Hyung Geun Moon ),( Se Young Lim ),( Pann Ghill Suh ),( Yoon Keun Kim ),( Chi Bom Chae ),( Yong Song Gho ) 한국생화학분자생물학회 (구 한국생화학회) 2008 생화학분자생물학회 춘계학술발표논문집 Vol.2008 No.-