STUDY OF INTELLIGENT ENGINEERING DRAWING PROCESSING SYSTEM

Guoan, Gao,Kai, Gong Mao,Wei, Zhang,Feng, Shen Yun 대한전자공학회 1992 HICEC:Harbin International Conference on Electroni Vol.1 No.1

An intelligent Mechanical Drawing Recognition System (MDRS) is described in this paper. MDRS consists of two subsystems: the General Drawing Scanning Input System (GDSIS) and the Part Drawing Understanding System (PDUS), which are independent each other but integrated together. Some new algorithems and conceptions are presented.

A pilot study on differential expression of microRNAs in the ventromedial prefrontal cortex and serum of sows in activity restricted crates or activity free pens

Guoan Yin,Liwei Guan,Langchao Yu,Dapeng Huang 아세아·태평양축산학회 2019 Animal Bioscience Vol.32 No.9

Objective: Physical activity restriction in sows may lead to behavioral abnormalities and affective disorders. However, the psychophysiological state of these sows is still unclear. As miRNAs can be used as effective markers of psychopathy, the present study aimed to assess the difference in microRNA expression between the long-term activity restricted sows and activity free sows, thus contributing to the understanding of abnormal sow behavior. Methods: Four dry sows (sixth parity, Large×White genetic line) were selected from activity restricted crates (RC) or activity free pens (FP) separately. microRNAs in the ventromedial prefrontal cortex (vMPFC) and serum were examined using real-time polymerase chain reaction, and the correlation between the miRNAs expressed in the vMPFC and serum was evaluated. Results: miR-134 (1.11 vs 0.84) and miR-1202 (1.09 vs 0.85) levels were higher in the vMPFC of the RC sows than in the FP sows (p<0.01). Furthermore, miR-132 (1.27 vs 1.08) and miR-335 (1.03 vs 0.84) levels were also higher in the RC sows than in FP sows (p<0.05); however, miR-135a, miR-135b, miR-16, and miR-124 levels were not different (p>0.05). The relative expression of serum miR-1202 was higher in the RC sows than in the FP sows (1.04 vs 0.54) (p<0.05), and there was a strong correlation (R = 0.757, p<0.05) between vMPFC and Serum levels of miR-1202. However, no significant difference was observed in miR-16 levels in the serum of the RC sows and FP sows (p>0.05). Conclusion: This pilot study demonstrates that long-term activity restriction in sows likely results in autism or other complex psychopathies with depression-like behaviors. These observations may provide new insights for future studies on abnormal behavior in sows and contribute to research on human psychopathy.

Quantum Secure Communication Protocol Based on Single-photon

Guoan Zhao 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.3

Two-way quantum secure communication protocol and one-way quantum secure communication protocol based on single photon sequence and the XOR operation have been proposed, one-way communication can confuse the eavesdroppers and two-way communication only a single authentication and there is not visible to eavesdropping and delayed photon attack Trojan horse attack. The new agreement the use of single photon sequence and no regularity not only to achieve unconditional security, and semantics confuse eavesdroppers and has a high transmission efficiency, easy implementation, especially suitable for use in noisy channels.

Tibiofemoral articulation and axial tibial rotation of the knee after a cruciate retaining total knee arthroplasty

( Guoan Li ),( Chaochao Zhou ),( Sophia Li ),( Jia Yu ),( Timothy Foster ),( Hany Bedair ) 대한슬관절학회 2024 대한슬관절학회지 Vol.36 No.-

Purpose Numerous research has reported that total knee arthroplasty (TKA) cannot reproduce axial tibial rotations of normal knees. The objective of this study was to measure the tibiofemoral articular contact motions and axial tibial rotations of TKA knees to investigate the mechanism causing the knee kinematics change of after TKAs. Methods Eleven patients with unilateral cruciate retaining (CR) TKA were tested for measurements of knee motion during a weight-bearing flexion from 0° to 105° using an imaging technique. The tibiofemoral contact kinematics were determined using the contact points on medial and lateral surfaces of the tibia and femoral condyles. Axial tibial rotations were calculated using the differences between the medial and lateral articulation distances on the femoral condyles and tibial surfaces at each flexion interval of 15°. Results On femoral condyles, articular contact distances are consistently longer on the medial than on the lateral sides (p < 0.05) up to 60° of flexion, corresponding to internal tibial rotations (e.g., 1.3° ± 1.0° at 15-30° interval). On tibial surfaces, the articular contact point on the medial side moved more posteriorly than on the lateral side at low flexion angles, corresponding to external tibial rotations (e.g., -1.4° ± 1.8° at 15-30° interval); and more anteriorly than on the lateral sides at mid-range flexion, corresponding to internal tibial rotations (e.g., 0.8° ± 1.7° at 45-60° interval). At higher flexion, articular motions on both femoral condyles and tibial surfaces caused minimal changes in tibial rotations. Conclusions These results indicate that the axial tibial rotations of these TKA knees were mainly attributed to asymmetric articulations on the medial and lateral femoral condyles and tibial surfaces. The data can help understand the mechanisms causing axial tibial rotations of TKA knees and help improve implant designs for restoration of normal knee kinematics.

STUDY OF INTELLIGENT ENGINEERING DRAWING PROCESSING SYSTEM

Gao Guoan,Gong Mao Kai,Zhang Wei,Shen Yun Feng 대한전자공학회 1992 대한전자공학회 Conference Vol.1992 No.2

Highly efficient generation of T-DNA insertion lines and isolation of flanking sequence tags (FSTs) of Brachypodium distachyon

Hongjiang Han,Guoan Shen,Tianyue An,Bo Song,Suzhen Zhao,Xiaoquan Qi 한국식물생명공학회 2018 Plant biotechnology reports Vol.12 No.4

Brachypodium distachyon (Brachypodium) has been developed as a model system for the temperate grasses. Hence, establishing a large insertion mutant population and identifying T-DNA insertion sites are imperative for functional genomics studies. Currently, Brachypodium has an established T-DNA collection resource, but it is far less than needed. In addition, the conventional methods for the isolation of flanking sequence tags (FSTs) characterizing the T-DNA inserts, such as TAIL-PCR, adapter ligation-mediated PCR, and inverse PCR, are time-consuming, laborious, and expensive. In this study, Agrobacterium-mediated transformation system was optimized to generate T-DNA mutants. Approximately 7000 T-DNA insertion lines were obtained. Furthermore, a simple and highly efficient method was developed to isolate T-DNA flanking sequence tags (FSTs). The procedures simplified the multi-step reaction that is required for the conventional inverse PCR and several reactions were conducted within a microscale reaction system in one tube. It is flexible to isolate FSTs for either individual or large numbers of T-DNA lines. To rapidly process the large-scale sequence data, a serial of Perl scripts were developed using the Perl Programming Language (http://www.perl.org). Using these methods, a total of 794 flanking sequences were isolated and analyzed in detail. Although the methods were developed in the process of isolating and analyzing T-DNA flanking sequences of Brachypodium, it can be applied to other plants.

Photoluminescence from SiGe NPs: SiO_2 Thin Films Co-doped with Al

Kun Zhong,Guoan Cheng,Xiangqian Cheng,Ruiting Zheng,Zhisong Xiao 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.58 No.41

Different doses of Al atoms were implanted into SiGe-rich SiO2 thin films, and the impacts of the doping dose and the annealing temperature on the photoluminescence (PL) from these thin films were investigated. Al-doping promoted the nucleation of SiGe nanoparticles (NPs). The addition of Al enhanced the PL intensity owing to an increase in the number of nucleation sites. However, the Al impurity generated a deep recombination level in the band gap of the SiGe NPs. When the Al-doping dose was 6 X 10^(14) cm^(−2), the intensity of the PL reached a maximum.

THE INTEGRATION OF CAD/CAM/CAE BASED ON MULTI MODEL TECHNOLOGY IN THE DEVELOPMENT OF CYLINDER HEAD

Xiangyang Xu,Ulrich Weiss,Guoan Gao 한국자동차공학회 2002 International journal of automotive technology Vol.3 No.2

The integration of CAD/CAM/CAE in product development is the key to realize concurrent engineering.<br/> Generally, different systems are employed in product development departments. These different systems create a lot of troubles such as difficulty in communication, misunderstanding and so on. A new approach to integrate CAD/CAM/CAE in one system based on CATIA for the end-to-end process in cylinder head development is presented. Multi Model Technology (MMT) is used to create consistent and associated CAD models for the end-to-end process in cylinder head development. The concept and method to create and organize multi models are discussed. A typical four-layer structure of MMT for mechanical products is defined. The multi level structure of the cylinder head models based on MMT is provided. The CAD models of cylinder head created based on MMT can be used as the consistent model. All models in the downstream of cylinder head development such as structure analysis, CFD, sand core design, casting simulation and so on are associated with the CAD models. Practice shows the approach in this paper enables the development process to be carried concurrently and can obviously shorten time to the market, reduce product cost and improve product quality.

Pharmacokinetics and Biodistribution of Surface Modification Polymeric Nanoparticles

Mingxing Liu,Huifang Li,Guoan Luo,Qingfei Liu,Yiming Wang 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.4

The objective of this study is to investigate the pharmacokinetics and biodistribution of free breviscapine (BVP) and coated BVP-loaded poly (D, L-lactic acid) nanoparticles (BVP-PLANPs) in rats after i.v. administration. Coated BVP-PLA-NPs were prepared by the spontaneous emulsification solvent diffusion method and characterized. The BVP content in the NPs, the biological samples and in vitro release was measured by the high-performance liquid chromatography (HPLC). The mean sizes of coated BVP-PLA-NPs were 177 and 319 nm with a narrow distribution and smooth sphere shapes, entrapment efficiency of 86.9% and 93.1%, respectively. Drug release profiles in phosphate buffer and plasma exhibited a biphasic release phenomenon. After i.v. administration of free BVP and NPs suspensions in rats, area under plasma concentration-time curve and elimination t1/2 were increased 9.3-fold and 10.9-fold for 177 nm of NPs, and 4.4-fold and 17.1-fold for 319 nm of NPs compared with that of free BVP, respectively. NPs were mainly distributed in liver, spleen, heart and brain. In addition, NPs could penetrate blood brain barrier (BBB) and the particle size had some effect on pharmacokinetics and biodistribution. Coated BVP-PLA-NPs could effectively avoid the capture by the reticuloendothelial system and prolong the half-life of BVP. Moreover, these NPs could penetrate BBB and enhance the accumulation of BVP in brain.

Preparation of smooth self-supporting Ni /Cu multilayer

Fengju Gao,Ruiting Zheng,Guoan Cheng,Jing Yu 한국물리학회 2008 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.52 No.-

[Ni(5 nm)/Cu(5 nm)]50 multilayer was deposited on SiN membranes by DC magnetron sputtering. Field emission scanning-electron microscopy (FESEM), atomic-force microscopy (AFM), and X-ray diffraction (XRD) were used to analyze the surface morphology and the microstructure. The surface of the multilayer is continuous and flat, with root-mean-square roughness (RMS) of 9.9 nm. The period of the multilayer is 10.7 nm, which is very close to the designed period of 10 nm. The multilayer was composed of multi-crystal. These results show that this experiment is a promising way to obtain flat self-supporting metal multilayer. [Ni(5 nm)/Cu(5 nm)]50 multilayer was deposited on SiN membranes by DC magnetron sputtering. Field emission scanning-electron microscopy (FESEM), atomic-force microscopy (AFM), and X-ray diffraction (XRD) were used to analyze the surface morphology and the microstructure. The surface of the multilayer is continuous and flat, with root-mean-square roughness (RMS) of 9.9 nm. The period of the multilayer is 10.7 nm, which is very close to the designed period of 10 nm. The multilayer was composed of multi-crystal. These results show that this experiment is a promising way to obtain flat self-supporting metal multilayer.