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( Duc Trong Quach ),( Ngoi Huu Dao ),( Minh Cao Dinh ),( Chung Huu Nguyen ),( Linh Xuan Ho ),( Nha Doan Thi Nguyen ),( Quang Dinh Le ),( Cong Minh Hong Vo ),( Sang Kim Le ),( Toru Hiyama ) 대한간학회 2016 Gut and Liver Vol.10 No.3
Background/Aims: To compare the performance of a modified Glasgow Blatchford score (mGBS) to the Glasgow Blatchford score (GBS) and the pre-endoscopic Rockall score (RS) in predicting clinical interventions in Vietnamese patients with acute nonvariceal upper gastrointestinal bleeding (ANVUGIB). Methods: A prospective multicenter cohort study was conducted in five tertiary hospitals from May 2013 to February 2014. The mGBS, GBS, and pre-endoscopic RS scores were prospectively calculated for all patients. The accuracy of mGBS was compared with that of GBS and preendoscopic RS using area under the receiver operating characteristic curve (AUC). Clinical interventions were defined as blood transfusions, endoscopic or radiological intervention, or surgery. Results: There were 395 patients including 128 (32.4%) needing endoscopic treatment, 117 (29.6%) requiring blood transfusion and two (0.5%) needing surgery. In predicting the need for clinical intervention, the mGBS (AUC, 0.707) performed as well as the GBS (AUC, 0.708; p=0.87) and outperformed the pre-endoscopic RS (AUC, 0.594; p<0.001). However, none of these scores effectively excluded the need for endoscopic intervention at a threshold of 0. Conclusions: mGBS performed as well as GBS and better than pre-endoscopic RS for predicting clinical interventions in Vietnamese patients with ANVUGIB. (Gut Liver 2016;10:375- 381)
Duc T Quach,Trang T Nguyen,Toru Hiyama 대한소화기 기능성질환∙운동학회 2018 Journal of Neurogastroenterology and Motility (JNM Vol.24 No.2
Background/Aims There have been no studies investigating the distribution of abnormal gastroesophageal flap valve (GEFV) among patients with dyspepsia, non-erosive reflux disease (NERD), and reflux esophagitis (RE) in the same set of patients. The aims of this study are to investigate (1) the association between GEFV and gastroesophageal reflux disease questionnaire (GERDQ) score, and (2) the distribution of abnormal GEFV in Vietnamese patients presenting with upper gastrointestinal symptoms. Methods Three hundred and thirty-one patients recruited in this prospective cross-sectional study were classified into 3 groups: reflux esophagitis (RE), non-erosive reflux disease (NERD) (GERDQ score ≥ 8, no endoscopic mucosal injury), and dyspepsia (GERDQ score < 8, no endoscopic mucosal injury). The GEFV was graded endoscopically according to the Hill classification. GEFV grades I and II were regarded as normal, while grades III and IV were regarded as abnormal GEFV. Results There were 215 (65.0%) patients with dyspepsia, 55 (16.6%) patients with NERD, and 61 (18.4%) patients with RE. Abnormal GEFV was an independent risk factor for GERD (OR, 2.93; CI 95%, 1.76–4.88) and RE (OR, 3.41; CI 95%, 1.78–6.53). The mean GERDQ score of patients with abnormal GEFV was significantly higher than that of patients with normal GEFV (5.7 ± 2.4 vs 4.9 ± 2.7, P = 0.011). The prevalence of abnormal GEFV gradually increased in patients with dyspepsia (27.4%), NERD (43.6%), grade A RE (56.8%), and grades B/C RE (80.0%) (P < 0.001). Conclusions Abnormal GEFV was significantly associated with high GERDQ score. Its prevalence gradually increased in patients with dyspepsia, NERD, and RE, respectively.
Clinical, Endoscopic and Pathogical Characteristics of Early-Onset Colorectal Cancer in Vietnamese
Quach, Duc Trong,Nguyen, Oanh Thuy Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.5
Background: The Asia Pacific consensus for colorectal cancer (CRC) recommends that screening programs should begin by the age of 50. However, there have been reports about increasing incidence of CRC at a younger age (i.e. early-onset CRC). Little is known about the features of early-onset CRC in the Vietnamese population. Aim: To describe the clinical, endoscopic and pathological characteristics of early-onset CRC in Vietnamese. Method: A prospective, cross-sectional study was conducted at the University Medical Center from March 2009 to March 2011. All patients with definite pathological diagnosis of CRC were recruited. The early-onset CRC group were analyzed in comparison with the late-onset (i.e. ${\geq}$ 50-year-old) CRC group. Results: The rate of early-onset CRC was 28% (112/400) with a male-to-female ratio of 1.3. Some 22.3% (25/112) of the patients only experienced abdominal pain and/or change in bowel habit without alarming symptoms, 42.9% (48/112) considering their symptoms intermittent. The rate of familial history of CRC in early-onset group was significantly higher that of the late-onset group (21.4% versus 7.6%, p<0.001). The distribution of CRC lesions in rectum, distal and proximal colon were 51.8% (58/112), 26.8% (30/112) and 21.4% (24/112), respectively; which was not different from that in the late-onset group (${\chi}2$, p = 0.29). The rates for poorly differentiated tumors were also not significantly different between the two groups: 12.4% (14/112) versus 8.3% (24/288) (${\chi}2$, p = 0.25). Conclusion: A high proportion of CRC in Viet Nam appear at an earlier age than that recommended for screening by the Asia Pacific consensus. Family history was a risk factor of early-onset CRC. Diagnosis of early-onset CRC needs more attention because of the lack of alarming symptoms and their intermittent patterns as described by the patients.
Duc Trong Quach,Toru Hiyama 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.4
The assessment of endoscopic gastric atrophy (EGA) according to the Kimura-Takemoto classification has been reported to correlatewell with histological assessment. Although agreement among beginner endoscopists was less than that among experiencedendoscopists, it has been shown that agreement level could markedly improve and remained stable after proper training. Severalcohort studies have consistently shown that the severity of EGA at baseline is significantly associated with the presence of advancedprecancerous gastric lesions and gastric cancer, as well as the development of gastric cancer in future. Patients with moderate-to-severeEGA still have high risk of gastric cancer even after successful Helicobacter pylori eradication and should be candidates for gastriccancer surveillance. The assessment of EGA, therefore, could be used as a preliminary tool to identify individuals at high risk forgastric cancer. In this paper, we review the agreement on mucosal atrophy assessment between the Kimura-Takemoto classification andhistology as well as the potential application of this endoscopic classification to identify precancerous gastric lesions and gastric cancerin daily practice.
Nanometer-scale local probing of X-ray absorption spectra of Co/Pt multilayer film
Quach, Duy-Truong,Pham, Duc-Thang,Handoko, Djati,Shim, Je-Ho,Eon Kim, Dong,Lee, Kyung-Min,Jeong, Jong-Ryul,Kim, Namdong,Shin, Hyun-Joon,Kim, Dong-Hyun Elsevier 2018 PHYSICA B-CONDENSED MATTER - Vol.532 No.-
<P><B>Abstract</B></P> <P>We report our local X-ray absorption spectra (XAS) measurement mapping for a Co/Pt multilayer using scanning transmission microscopy with 25-nm spatial resolution and 0.1-eV spectral resolution. We have systematically analyzed the two-dimensional XAS intensity variation over the corresponding magnetic domain patterns, revealing a XAS profile across the magnetic domain wall as well as the simultaneous high-throughput measurement of local XAS spectra.</P>
Quach, Hung,Kim, Jin-Jae,Nguyen, Duc-Toan,Kim, Young-Suk Elsevier 2020 International journal of mechanical sciences Vol.169 No.-
<P><B>Abstract</B></P> <P>A new phenomenological ductile fracture criterion that is proposed. The proposed model is associated with the micro mechanisms of void nucleation, void growth, and evolution of void coalescence. The secondary voids band and rotation of voids effect are considered in the new ductile fracture criterion. A series of upsetting test results of aluminum 2024-T351 and TRIP RA-K40/70 steel are used to construct and compare the accuracy of fracture locus proposed by new ductile fracture criterion, Modified Mohr-Coulomb criterion and extend Lou-Huh criterion. The fracture locus constructed using the proposed criterion is close to the experimental data points over a wide stress state range from uniaxial compression to balanced biaxial tension. Then, a series of upsetting tests and square cup drawing tests are conducted with Al6014-T4 to evaluate the accuracy of the proposed criterion. All results indicate that the proposed ductile fracture criterion can be utilized for predicting initial fracture in sheet metal forming.</P> <P><B>Highlights</B></P> <P> <UL> <LI> A new phenomenological ductile fracture criterion considering micro mechanisms of void nucleation, void growth, and evolution of void coalescence is presented in this paper. </LI> <LI> The secondary voids band and rotation of voids effect are considered in the new ductile fracture criterion. </LI> <LI> The new ductile fracture criterion can be utilized for predicting initial fracture in sheet metal forming with lager range of stress triaxiality. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Microscopic Investigation of the Magnetic Saturation Process for Co/Pt Multilayers
Duy-Truong Quach,Dong-Hyun Kim,Kyung-Min Lee,정종율,Duc-Thang Pham 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.69 No.1
We have systematically investigated the magnetic saturation process for Co/Pt multilayers with perpendicular magnetic anisotropy by using the first-order reversal-curve (FORC) technique. We find that even for a field that apparently is higher than the major-loop saturation field, some microscopically not-yet-annihilated domains still remain. The true saturation on a microscopic scale field is found to be about 1.5 to 2.5 times greater than the macroscopicall-determined majorloop saturation field. Not-yet-annihilated domains are observed to be exponentially reduced with respect to the applied magnetic field.
Ha-Linh Quach,Thai Quang Pham,Ngoc-Anh Hoang,Dinh Cong Phung,Viet-Cuong Nguyen,Son Hong Le,Thanh Cong Le,Dang Hai Le,Anh Duc Dang,Duong Nhu Tran,Nghia Duy Ngu,Florian Vogt,Cong-Khanh Nguyen 대한의료정보학회 2022 Healthcare Informatics Research Vol.28 No.4
Objectives: Online misinformation has reached unprecedented levels during the coronavirus disease 2019 (COVID-19) pandemic. This study analyzed the magnitude and sentiment dynamics of misinformation and unverified information about public health interventions during a COVID-19 outbreak in Da Nang, Vietnam, between July and September 2020. Methods: We analyzed user-generated online information about five public health interventions during the Da Nang outbreak. We compared the volume, source, sentiment polarity, and engagements of online posts before, during, and after the outbreak using negative binomial and logistic regression, and assessed the content validity of the 500 most influential posts. Results: Most of the 54,528 online posts included were generated during the outbreak (n = 46,035; 84.42%) and by online newspapers (n = 32,034; 58.75%). Among the 500 most influential posts, 316 (63.20%) contained genuine information, 10 (2.00%) contained misinformation, 152 (30.40%) were non-factual opinions, and 22 (4.40%) contained unverifiable information. All misinformation posts were made during the outbreak, mostly on social media, and were predominantly negative. Higher levels of engagement were observed for information that was unverifiable (incidence relative risk [IRR] = 2.83; 95% confidence interval [CI], 1.33–0.62), posted during the outbreak (before: IRR = 0.15; 95% CI, 0.07–0.35; after: IRR = 0.46; 95% CI, 0.34-0.63), and with negative sentiment (IRR = 1.84; 95% CI, 1.23–2.75). Negatively toned posts were more likely to be misinformation (odds ratio [OR] = 9.59; 95% CI, 1.20–76.70) or unverified (OR = 5.03; 95% CI, 1.66–15.24). Conclusions: Misinformation and unverified information during the outbreak showed clustering, with social media being particularly affected. This indepth assessment demonstrates the value of analyzing online “infodemics” to inform public health responses.