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Yue Lin,Yuanyuan Zhang,Qiongtao Song,Tao Song,Xue Han,Ying Zhang,Xuan Zhang,Xi Chu,Fenghua Zhang,Li Chu,Jianping Zhang 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.10
To explore the cardiovascular protective effectsof Magnesium isoglycyrrhizinate (MI), especially theunderlying cellular mechanisms related to L-type calciumchannels and myocardial contractility, and to examine theeffects of MI on hERG K? current expressed in HEK293cells. We used the whole-cell patch clamp technique,video-based edge detection and dual excitation fluorescencephotomultiplier systems to explore the effect of MIon L-type Ca2? currents (ICa-L) and cell contraction in ratcardiomyocytes. We also examined the rapidly activatingdelayed rectifier potassium current (IKr) expressed inHEK293 cells using a perforated patch clamp. MI inhibitedICa-L in a dose-dependent manner, with a half-maximalinhibitory concentration (IC50) of 0.22 mg/ml, and themaximal inhibitory effect was 61.10 ± 0.59%. MI at aconcentration of 0.3 mg/ml reduced cell shortening by24.12 ± 3.97% and the peak value of the Ca2? transient by36.54 ± 4.96%. MI had no significant influence on hERGK? channels expressed in HEK293 cells at all testpotentials. MI exerts protective effects on the heart via theinhibition of ICa-L and cell shortening in rat cardiomyocytes. However, MI had no significant influence on IKr;thus, MI may exert cardioprotective effects without causingdrug-induced long QT syndrome.
THE GEOMETRIC CONVEXITY OF A FUNCTION INVOLVING GAMMA FUNCTION WITH APPLICATIONS
Chu, Yuming,Zhang, Xiaoming,Zhang, Zhihua Korean Mathematical Society 2010 대한수학회논문집 Vol.25 No.3
In this paper, we prove that $(\Gamma(x))^{\frac{1}{x-1}}$ is geometrically convex on (0, $\infty$). As its applications, we obtain some new estimates for $\frac{[\Gamma(x+1)]^{\frac{1}{x}}} {[\Gamma(y+1)]^{\frac{1}{y}}}$.
Zhang, Yonggang,Ren, Li,Chu, Huaqiang,Zhou, Xuefei,Yao, Tianming,Zhang, Yalei The Korean Society for Microbiology and Biotechnol 2019 한국미생물·생명공학회지 Vol.47 No.4
Microalgae have been explored as potential host species for biofuel production. Environmental factors affect algal growth and cellular composition. The effects of several key environmental factors, such as temperature, light, and pH of the medium on the growth and biochemical composition of Scenedesmus obliquus were investigated in this study. The highest growth rate of microalgae was observed at an optimal temperature of 25℃, 150 μmol/(m<sup>2</sup>·s) light intensity, and pH 10.0. The biochemical composition analysis revealed that the carbohydrate content decreased at lower (20℃) or higher temperature (35℃), whereas the protein and lipid contents increase at these temperatures. The fluctuation of light intensity significantly affected the contents of protein, carbohydrate, and lipid. The protein levels varied greatly when the pH of the medium was below 7.0. The carbohydrate and lipid contents significantly increased at pH above 7.0.
Yonggang Zhang,Li Ren,Hua-qiang Chu,Xue-fei Zhou,Tianming Yao,Ya-lei Zhang 한국미생물·생명공학회 2019 한국미생물·생명공학회지 Vol.47 No.4
Microalgae have been explored as potential host species for biofuel production. Environmental factors affect algal growth and cellular composition. The effects of several key environmental factors, such as temperature, light, and pH of the medium on the growth and biochemical composition of Scenedesmus obliquus were investigated in this study. The highest growth rate of microalgae was observed at an optimal temperature of 25℃, 150 μmol/(m2·s) light intensity, and pH 10.0. The biochemical composition analysis revealed that the carbohydrate content decreased at lower (20℃) or higher temperature (35℃), whereas the protein and lipid contents increase at these temperatures. The fluctuation of light intensity significantly affected the contents of protein, carbohydrate, and lipid. The protein levels varied greatly when the pH of the medium was below 7.0. The carbohydrate and lipid contents significantly increased at pH above 7.0.
Bo Zhang,Yong Yang,Yuan-feng Wei,Ru-yue Liu,Chu Ding,Ke-qiang Zhang 국제구조공학회 2015 Structural Engineering and Mechanics, An Int'l Jou Vol.55 No.6
In this study, a new retrofitting method for improving the seismic performance of reinforced concrete column was presented, in which prestressed steel strips were utilized as retrofitting stuff to confine the reinforced concrete column transversely. In order to figure out the seismic performance of concrete column specimen retrofitted by such prestressed steel strips methods, a series of quasi-static tests of five retrofitted specimens and two unconfined column specimen which acted as control specimens were conducted. Based on the test results, the seismic performance including the failure modes, hysteresis performance, ductility performance, energy dissipation and stiffness degradation of all these specimens were fully investigated and analyzed. And furthermore the influences of some key parameters such as the axial force ratios, shear span ratios and steel strips spacing on seismic performance of those retrofitted reinforced concrete column specimens were also studied. It was shown that the prestressed steel strips provided large transverse confining effect on reinforced concrete column specimens, which resulted in improving the shearing bearing capacity, ductility performance, deformation capacity and energy dissipation performance of retrofitted specimens effectively. In comparison to the specimen which was retrofitted by the carbon fiber reinforced plastics (CFRP) strips method, the seismic performance of the specimens retrofitted by the prestressed steel strips was a bit better, and with much less cost both in material and labor. From this research results, it can be concluded that this new retrofitting method is really useful and has significant advantages both in saving money and time over some other retrofitting methods.
Temporal and spatial variation analysis on nutritive salt of Hongze Lake
Min Zhang,Enguo Chu,Ming Xu,Jun Guo,Yong Zhang 대한환경공학회 2015 Environmental Engineering Research Vol.20 No.1
This paper mainly focuses on the research of the monitoring data about the total nitrogen (TN), total phosphorus (TP) of ten monitoring points of Hongze Lake in 28 years. Our study adopts the technical methods such as difference comparison, correlation analysis, Mann-Kendall, etc. to analyze the statistical characteristics, regional differences, and temporal and spatial variation condition of ten monitoring points of Hongze Lake in 1986-2013 as well as the reason for the time and space variation of TN and TP. The results show that the TN and TP of Hongze Lake change dramatically during the period of 1994-2004. In all the monitoring periods, TN and TP of the HZ5, HZ6, HZ7, HZ8 monitoring points in the estuary surrounding the Huaihe River are the highest, which suggests that TN and TP of Hongze Lake should not be ignored for the pollution along the Huaihe River. The TN concentration in the core area is the highest, but that in the development control area is the lowest. In most of the years, TN concentration is higher than 2 mg/L, and the water quality is V class and poor V class water quality in China``s Environmental Quality Standards for Surface Water (GB3838-2002). TP concentration of the three areas is basically close, that is lower than 2 mg/L in most of the years, and the water quality is within the V class. The TN and TP concentration of Hongze Lake decreased and intensifying trend of eutrophication is controlled after 2004.
Yanjie Zhang,Ruiqing Chu,Zhi-Jun Xu,Qian Chen,Yong Liu,Guangchao Zhang 한국물리학회 2012 Current Applied Physics Vol.12 No.1
(Bi0.5Na0.5)0.94Ba0.06TiO3 ceramics doped with Li2CO3 and Bi2O3 as sintering aids were manufactured, and their micro structural, dielectric and piezoelectric properties were investigated. All specimens could be well sintered at a low-temperature of 1080 ℃. The bulk density of the specimens doped with a small amount of Li2CO3 was enhanced. The dielectric and piezoelectric properties of ceramics were investigated with different amounts of Li2CO3 substitutions. High electrical properties of d33 ¼ 167 pC/N,kp ¼ 0.34, Pr ¼ 40 mC/cm2 and Ec ¼ 38 kV/cm were obtained from the specimen containing 0.1 mol% of Li2CO3 sintered at 1080 ℃.
장추(Chu Zhang),홍원화(Won-Hwa Hong),배영훈(Young-Hoon Bae) 한국화재소방학회 2024 한국화재소방학회논문지 Vol.38 No.1
본 연구에서는 개인과 지역사회의 화재대응능력을 고려한 화재 위험성 평가를 위해, 화재대응능력에 영향을 미치는 요소 중 하나인 가구 구성에 따른 화재대응능력을 설문조사를 통해 분석하고, 통계분석을 통해 가구 구성이 화재피해에 미치는 영향을 분석하여, 화재대응능력을 고려한 화재 위험성 평가의 가능성을 제시하고자 한다. 설문조사결과, 가구 구성에 따른 화재대응능력은 통계적으로 유의미한 차이를 보였으며, 개인의 화재대응능력은 다인 가구에서 더 높게, 지역사회의 화재대응능력은 1인 가구에서 더 높게 나타났다. 또한 통계분석 결과, 1인 가구의 수와 화재발생 건수 및 인명피해는 양의 상관관계를 보이는 것으로 나타났다. 최종적으로 본 논문에서는 설문조사와 상관성분석 결과 고찰을 통해 화재대응능력의 활용 가능성을 제시한다. In this study, to conduct a comprehensive fire risk assessment (FRA) considering the fire coping capacity (FCC) ofindividuals and communities, we analyzed the FCC based on household composition, a factor influencing FCC, through asurvey. Statistical analysis was employed to examine the impact of household composition on fire damage with the aim ofproposing the feasibility of an FRA incorporating FCC. The survey results indicated a statistically significant difference inthe FCC based on household composition, with a higher individual fire response capability in multi-person households andan elevated community FCC in single-person households. Furthermore, the statistical analysis revealed a positive correlationbetween the number of single-person households and the occurrence of fire incidents and casualties. In conclusion, this studyexplored the potential of FCC in FRA by drawing insights from the survey and correlation analysis results.