http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Choi, Dukhyun,Choi, Min-Yeol,Choi, Won Mook,Shin, Hyeon-Jin,Park, Hyun-Kyu,Seo, Ju-Seok,Park, Jongbong,Yoon, Seon-Mi,Chae, Seung Jin,Lee, Young Hee,Kim, Sang-Woo,Choi, Jae-Young,Lee, Sang Yoon,Kim, Jo WILEY-VCH Verlag 2010 ADVANCED MATERIALS Vol.22 No.19
<B>Graphic Abstract</B> <P>The cover shows an image of fully rollable transparent nanogenerators synthesized using chemical vapor deposition grown large-scale graphene sheets as transparent electrodes and piezoelectric ZnO nanorod arrays. Sang-Woo Kim, Jae-Young Choi, and co-workers report on p. 2187 the electrical and structural stability of the nanogenerators, with excellent charge scavenging performance under external mechanical loads such as bending and rolling. This study shows that graphene-based nanogenerators are very promising for self-powered rollable transparent device applications. <img src='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content.gif' alt='wiley_img_2010/09359648-2010-22-19-ADMA201090066-content'> </P>
Effect of the Ethanol Extract of Propolis on Formation of Streptococcus mutans Biofilm
Bog-Im Park,Yeon-Woo Jung,Young-Hoi Kim,Sang-Moo Lee,Lee-Seong Kwon,Kang-Ju Kim,So-Youn An,Na-Young Choi6,Yong-Ouk You 대한구강생물학회 2016 International Journal of Oral Biology Vol.41 No.4
Streptococcus mutans (S. mutans) is one of the most important bacteria in the formation of dental plaque and dental caries. S. mutans adheres to an acquired pellicle formed on the tooth surface, and aggregates with many oral bacteria. It initiates plaque formation by synthesizing glucan from sucrose, which is catalyzed by glucosyltransferases. Propolis is a resinous mixture produced by honeybees, by mixing saliva and beeswax with secretions gathered from wood sap and flower pollen. Bees prevent pathogenic invasions by coating the propolis to the outer and inner surface of the honeycomb. Propolis has traditionally been used for the treatment of allergic rhinitis, asthma and dermatitis. We investigated the inhibitory effects of propolis ethanol extract on biofilm formation and gene expression of S. mutans. The biofilm formation of S. mutans was determined by scanning electron microscopy (SEM) and safranin staining. We observed that the extract of propolis had an inhibitory effect on the formation of S. mutans biofilms at concentrations higher than 0.2 mg/ml. Real-time PCR analysis showed that the gene expression of biofilm formation, such as gbpB, spaP, brpA, relA and vicR of S. mutans, was significantly decreased in a dose dependent manner. The ethanol extract of propolis showed concentration dependent growth inhibition of S. mutans, and significant inhibition of acid production at concentrations of 0.025, 0.05, 0.1 and 0.2 mg/ml, compared to the control group. These results suggest that the ethanol extract of propolis inhibits gene expression related to biofilm formation in S. mutans.
Transcriptome analysis of a tropical medicinal plant, Pistacia weinmannifolia
Mi Kyung Choi(Mi Kyung Choi),Bimpe Suliyat Azeez(Bimpe Suliyat Azeez ),Sang Woo Lee(Sang Woo Lee),Wan Yi Li(Wan Yi Li),Sangho Choi(Sangho Choi),Ik-Young Choi(Ik-Young Choi),Ki-Young Choi(Ki-Young (사)한국식물생명공학회 2024 JOURNAL OF PLANT BIOTECHNOLOGY Vol.51 No.1
Bio‐Inspired Complementary Photoconductor by Porphyrin‐Coated Silicon Nanowires
Choi, Sung‐,Jin,Lee, Young‐,Chul,Seol, Myeong‐,Lok,Ahn, Jae‐,Hyuk,Kim, Sungho,Moon, Dong‐,Il,Han, Jin‐,Woo,Mann, Stephen,Yang, Ji‐,Won,Choi, Yang‐,Kyu WILEY‐VCH Verlag 2011 Advanced Materials Vol.23 No.34
<P><B>A symbiotically bio‐inspired complementary photoconductor</B> is demonstrated using a well‐defined silicon nanowire (SiNW) and porphyrins. The observed direction of the conductance change by light illumination has opposite signs for n‐ and p‐type SiNWs. On the basis of this observation, it is concluded that complementary photoconductors can be used to form functional logic gates of optical input with remarkably low static power dissipation.</P>
Choi, Woo-Hee,Chung, Yong-An,Sohn, Hyung-Sun,Park, Young-Hak,Shim, Sang-In The Korea Society of Nuclear Medicine 2010 핵의학 분자영상 Vol.44 No.2
A 68-year-old man underwent total gastrectomy for stomach cancer. On the follow-up FDG PET/CT image 18 months later, intense focal $^{18}F$-fluorodeoxyglucose (FDG) uptake was noted in the right parapharyngeal space. This lesion showed intermediate signal intensity on T1-weighted image and heterogeneous high signal intensity on T2-weighted image. The mass was heterogenously enhanced by gadolinium enhancement. This lesion was pathologically confirmed as pleomorphic adenoma by excision. This case highlights the fact that both benign and malignant lesions in the parotid gland may exhibit intense FDG activity and the need for pathologic confirmation of parotid gland lesions for accurate disease staging.
Transduced Tat-α-Synuclein Protects against Oxidative Stress In vitro and In vivo
Choi, Hee-Soon,Lee, Sun-Hwa,Kim, So-Young,An, Jae-Jin,Hwang, Seok-Il,Kim, Dae-Won,Yoo, Ki-Yeon,Won, Moo-Ho,Kang, Tae-Cheon,Kwon, Hyung-Joo,Kang, Jung-Hoon,Cho, Sung-Woo,Kwon, Oh-Shin,Choi, Jin-Hi,Park Korean Society for Biochemistry and Molecular Biol 2006 Journal of biochemistry and molecular biology Vol.39 No.3
Parkinson's disease (PD) is a common neurodegenerative disorder and is characterized by the progressive loss of dopaminergic neurons in the substantia nigra. Although many studies showed that the aggregation of $\alpha$-synuclein might be involved in the pathogenesis of PD, its protective properties against oxidative stress remain to be elucidated. In this study, human wild type and mutant $\alpha$-synuclein genes were fused with a gene fragment encoding the nine amino acid trans activator of transcription (Tat) protein transduction domain of HIV-l in a bacterial expression vector to produce a genetic in-frame WT Tat-$\alpha$-synuclein (wild type) and mutant Tat-a-synucleins (mutants; A30P and A53T), respectively, and we investigated the protective effects of wild type and mutant Tat-$\alpha$-synucleins in vitro and in vivo. WT Tat-$\alpha$-synuclein rapidly transduced into an astrocyte cells and protected the cells against paraquat induced cell death. However, mutant Tat-$\alpha$-synucleins did not protect at all. In the mice models exposed to the herbicide paraquat, the WT Tat-$\alpha$-synuclein completely protected against dopaminergic neuronal cell death, whereas mutants failed in protecting against oxidative stress. We found that these protective effects were characterized by increasing the expression level of heat shock protein 70 (HSP70) in the neuronal cells and this expression level was dependent on the concentration of transduced WT Tat-$\alpha$-synuclein. These results suggest that transduced Tat-$\alpha$-synuclein might protect cell death from oxidative stress by increasing the expression level of HSP70 in vitro and in vivo and this may be of potential therapeutic benefit in the pathogenesis of PD.
Inhibitory Properties of Nerve-Specific Human Glutamate Dehydrogenase Isozyme by Chloroquine
Choi, Myung-Min,Kim, Eun-A,Choi, Soo-Young,Kim, Tae-Ue,Cho, Sung-Woo,Yang, Seung-Ju Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.6
Human glutamate dehydrogenase exists in hGDH1 (housekeeping isozyme) and in hGDH2 (nerve-specific isozyme), which differ markedly in their allosteric regulation. In the nervous system, GDH is enriched in astrocytes and is important for recycling glutamate, a major excitatory neurotransmitter during neurotransmission. Chloroquine has been known to be a potent inhibitor of house-keeping GDH1 in permeabilized liver and kidneycortex of rabbit. However, the effects of chloroquine on nerve-specific GDH2 have not been reported yet. In the present study, we have investigated the effects of chloroquine on hGDH2 at various conditions and showed that chloroquine could inhibit the activity of hGDH2 at dose-dependent manner. Studies of the chloroquine inhibition on enzyme activity revealed that hGDH2 was relatively less sensitive to chloroquine inhibition than house-keeping hGDH1. Incubation of hGDH2 was uncompetitive with respect of NADH and non-competitive with respect of 2-oxoglutarate. The inhibitory effect of chloroquine on hGDH2 was abolished, although in part, by the presence of ADP and L-leucine, whereas GTP did not change the sensitivity to chloroquine inhibition. Our results show a possibility that chloroquine may be used in regulating GDH activity and subsequently glutamate concentration in the central nervous system.