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( Chao Dong ),( Han Jun Li ),( Shi Chang ),( Hui Jun Liao ),( Zhi Peng Zhang ),( Peng Huang ),( Hui Huan Tang ) 대한간학회 2013 Gut and Liver Vol.7 No.2
Background/Aims: We aimed to investigate the correlation between a disintegrin and metalloprotease with thrombospondin motif 2 (ADAMTS-2) and transforming growth factor-β1 (TGF-β1) in clinical human cirrhotic tissues. Methods: The liver tissues of 24 patients (16 cases with cirrhotic portal hypertension as the cirrhosis group and eight cases with healthy livers as the normal group) were collected. Immunohistochemistry and Western blots were performed to evaluate the protein expression levels of ADAMTS-2 and TGF-β1. Western blots for other key mediators of cirrhotic progression, including SMAD2, SMAD3, TGF-β receptor II (TGFβRII), matrix metalloproteinases 2 (MMP2), and tissue inhibitor of matrix metalloproteinases 2 (TIMP2), were also performed. Results: Cirrhotic tissues showed higher percentages of collagen. The protein expression levels of ADAMTS-2 and TGF-β1 were significantly higher in the cirrhotic group as compared to the matched normal group (p<0.05), and there was a positive correlation between these two proteins (r=0.862, p<0.01). The protein expressions of MMP2, TIMP2, and TGFβRII, as well as the phosphorylated forms of SMAD2 and SMAD3, were significant higher in the cirrhotic group (p<0.01 or p<0.05). Conclusions: These findings suggested that ADAMTS-2 and TGF-β1 may play important roles in the pathogenesis of human cirrhosis; specifically, TGF-β1 may induce the expression of ADAMTS-2 through the TGFβ/SMAD pathway. (Gut Liver 2013;7:213-220)
Vibration analysis and dynamic performance improvement of high-frequency injection method
Peng, Wei,Qiao, Mingzhong,Jiang, Chao,Lu, Xihao,Zhu, Peng The Korean Institute of Power Electronics 2021 JOURNAL OF POWER ELECTRONICS Vol.21 No.2
This paper analyzes and compares the typical rotating high-frequency voltage injection (RTHF) method and the typical pulsating high-frequency voltage injection (PSHF) method in terms of torque ripple and vibration. Analysis and experiment results indicate that the PSHF performs better when it comes to torque pulsation and vibration. In addition, it is more suitable for rim motors which have strict restrictions on vibration. However, the estimated rotor position in PSHF has multiple convergence points. In addition, the filters used in PSHF can degrade the dynamic response of the PMSM sensorless field oriented control (SLFOC) system. An improved PSHF method compensated by Hall signals is proposed to accelerate the estimation process and improve the system stability in the presence of sudden load disturbances. The improved method is verified on an 11 kW rim motor experimental platform.
Chao-Chung Peng,Chieh-Li Chen,Christopher Edwards 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
This study proposes a synthetic control strategy for the reconstruction and rejection of mismatched and matched unknown disturbances. For a nonlinear scalar system, a nonlinear proportional-integral (PI) control is developed for dealing with matched disturbances. Next, a 2nd order system subjected to both matched and mismatched disturbances is considered. By incorporating the idea of backstepping design and conventional sliding mode control (SMC), the mismatched disturbance can be transformed into a matched one with respect to a virtual control input, and therefore the matching condition is extended. An extension of the proposed control framework for a class of multi-input multi-output (MIMO) systems is further provided.
Xiong Peng,Xiong Peng,Anhua Chen,Chao Zhao,Canlong Liu,Y. Frank Chen 국제구조공학회 2021 Smart Structures and Systems, An International Jou Vol.28 No.1
The falling offs of building decorative layers (BDLs) on exterior walls are quite common, especially in Asia, which presents great concerns to human safety and properties. Presently, there is no effective technique to detect the debonding of the exterior finish because debonding are hidden defect. In this study, the debonding defect identification method of building decoration layers via UAV-thermography and deep learning is proposed. Firstly, the temperature field characteristics of debonding defects are tested and analyzed, showing that it is feasible to identify the debonding of BDLs based on UAV. Then, a debonding defect recognition and quantification method combining CenterNet (Point Network) and fuzzy clustering is proposed. Further, the actual area of debonding defect is quantified through the optical imaging principle using the real-time measured distance. Finally, a case study of the old teaching-building inspection is carried out to demonstrate the effectiveness of the proposed method, showing that the proposed model performs well with an accuracy above 90%, which is valuable to the society.
Tao Peng,Dongxing Ren,Chao Kang,Huanhuan Liu,Peng Xue,Hai Huang 대한토목학회 2024 KSCE Journal of Civil Engineering Vol.28 No.5
This research aims to comprehensively study the deformation characteristics of an excavation pit of 7,600 m2 (117 m long, 65 m wide and 20.8 m deep) in soft clay in Shanghai, China. The deformation characteristics of the mixing pile in both the vertical and lateral directions, ground surface movement, and surface displacement in the adjacent tunnels were comprehensively investigated. The results indicated that the maximum lateral deflection was approximately 85 mmat the end of the excavation and that the maximum lateral displacement, hm, was in the range between 0.12%He and 0.41%He. The factor of safety of the excavation was approximately 1.6, which was larger than that of most reported sites in Shanghai. The relationship between heaving and excavation depth was strong between 0.0047%He and 0.056%He, and a relatively large settlement was observed at a distance of approximately 0.2He – 0.3He. The tunnel surface of the eastbound line deformed upward and inward with a maximum horizontal convergence of 4 mm. A multilayer regression model was also validated, showing a maximum discrepancy of 26.5 mm. This research provides a valuable historical case for the documentation of the deformation characteristics of excavation pits close to existing foundation pits and tunnels.
The simple and easy way to manufacture counter electrode for dye-sensitized solar cells
Jo-Lin Lan,Yung-Yun Wang,Chi-Chao Wan,Tzu-Chien Wei,Hsien-Ping Feng,Chao Peng,Hai-Peng Cheng,Ya-Huei Chang,Wen-Chi Hsu 한국물리학회 2010 Current Applied Physics Vol.10 No.2
We previously developed poly-N-vinyl-2-pyrrolidone (PVP)-capped Pt nanoclusters on ITO glass via a simple ‘‘2-step dip coating process” as counter electrode for DSSC. This new counter electrode was examined by transmission electron microscopy (TEM), inductively coupled plasma-atomic emission spectroscopy (ICP-AES), electrochemical impedance spectroscopy (EIS), cyclic voltammetry (CV), and current–voltage curve (I–V curve). The TEM results revealed that PVP-capped Pt nanoclusters’ size is about 3 nm, and the amount of Pt deposited on ITO glass is about 5 ㎍/㎠. Comparing with sputtered Pt and Solaronix thermal cluster Pt-catalyst T/SP, the PVP-capped Pt counter electrode has lower amount of Pt deposited on TCO glass,more positive potential of tri-iodide reduction, and better performance for the charge-transfer resistance (RCT) and the cell efficiency (g).
Chao-Tsai Huang,Jun-Zheng Wang,Cheng-Hong Lai,Sheng-Jye Hwang,Po-Wei Huang,Hsin-Shu Peng 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.4
Fiber reinforced thermoplastics (FRP) have been widely used in automotive industry. However, how does the flow-fiber coupling effect influence the micro fiber orientation and further affect the geometrical shrinkage of the final part that is not fully understood yet. In this study, a complex center-gated plate has been applied to study the influence of the flow-fiber coupling effect on the fiber orientation variation and the geometrical change through numerical simulation. Then the practical verification through the micro-computed tomography (micro-CT) and image processing technology was carried out. Results show that in the presence of the flow-fiber coupling the required spruce pressure will be higher compared to no coupling case. In addition, the melt flow front pattern will be changed from “convex-flat” to “convex-concave” under the influence of this coupling. Moreover, in the presence of the flow-fiber coupling effect, the wider core width for fiber orientation tensor in the flow direction (A11) can be obtained from upstream to downstream regions for the same model. However, in the downstream region (i.e. in the FR), the flow-fiber coupling effect is more significantly due to the action of less shear rate in that region. Finally, through the measurement of the left–right asymmetrical shape of the FR for Model I (or Model II), the reason is that the flow-fiber coupling effect will switch the fiber orientation from the flow direction (A11) dominate to the cross-flow direction (A22) dominate. This asymmetrical fiber orientation distribution will further create that asymmetrical shrinkage shape of final part. The correlation between fiber orientation and geometrical shrinkage can be achieved.