혈액종양 환자의 중심정맥 카테터에 대한 헤파린 관류와 생리식염수 관류의 효과 비교

문초희,연보라,김현진,은방희,배영이 병원간호사회 2006 임상간호연구 Vol.11 No.2

Purpose: The purpose of this study was to compare the efficacy of heparin flushing and normal saline flushing in maintaining patency of central venous catheters(CVCs), and to investigate relative risk factors of CVCs' occlusion. Method: A total of 159 patients who had been inserted with CVCs were included in the department of hemato-oncology of S hospital. The heparin group consisted of 74 patients with 10u/ml diluted heparin flushing from 23 November 2004 to 15 January 2005, and the normal saline group consisted of 85 patients with 0.9% normal saline flushing from 19 January to 31 March of 2005. Result: The heparin group was significantly different from the normal saline group in CVCs' occlusion. The normal saline group offered a much longer survival duration of CVCs' patency than the heparin group. Potential bleeding signs (PT, aPTT) had no significant differences. In multivariate analysis, 0.9% normal saline (hazard ratio 0.50), chemo port (hazard ratio 3.38), and no administration of TPN (hazard ratio 0.25) were the significant factors for occlusion of CVCs. Conclusion: For maintaining the patency of CVCs, 0.9% normal saline flushing are expected to be effective in reducing drug incompatibilities, lessening the bleeding tendency and improving cost effectiveness .

서울시내 고등학교 위탁급식의 급식비와 투자비의 실태 및 위탁업체의 기대수준 비교 분석

양일선,배환미,김현아,신서영,조미나,박수연,차진아,이보숙 한국식생활문화학회 2002 韓國食生活文化學會誌 Vol.17 No.5

The purposes of this study were to a) find out the operational characteristics of the contract-managed highschool foodservice in Seoul, b) investigate the expected level of meal-price and facilities investment cost perceived by contract-managed highschool foodservice managers c) compare the present level and expected level of meal-price and facilities investment cost. From October 12 to November 13 in 2001, the questionnaires were mailed to 249 high schools which was managed by contract foodservice company with respondent rate 40.2%. Data were analyzed using SPSS Win(10.0) for descriptive analysis and one group paired t-test. The results of this study were as follows ; 1. The student enrollment of highschools run by contract-managed foodservice was 1,243 with 72.6% participation rate of school lunch program. The average meal-price was 2,138 won. The average annual period of school foodservice operation was 156.78 days per year. The average contracting period was about 3 years. 2. The average cost concerned in the facilities investment amounts 169,578,180 won at the initial investment and 25,204,092 won at the repairs and maintenance cost in the course of operation. 3. The present level of meal-price and facilities investment cost were respectively 2,136won/meal and 171,157,336.72 won. And expected level.of meal-price and amount of facilities investment cost were 2,418.75 won and 121,353,215.19 won. Comparing the present level with expected level of the meal-price and facilities investment cost, expected level of meal-price was significantly higher than the present level of meal-price(p<.001) and expected level of facilities investment cost was significantly lower than present level of facilities investment cost(p<.001).

Amplitude Variation with Offset (AVO) Analysis for Gas-Hydrate Bottom-Simulating Reflectors (BSRs) in the Ulleung Basin, East Sea (Japan Sea)

Bo Yeon Yi,Gwang Hoon Lee,Senay Horozal,Dong Gun Yoo,Keun Pil Park,Ho Young Lee 대한지질학회 2008 대한지질학회 학술대회 Vol.2008 No.

Estimation of gas-hydrate concentrations from amplitude variation with offset (AVO) analysis of gas-hydrate BSRs in the Ulleung Basin, East Sea

이보연(Yi, Bo-Yeon),이광훈(Lee, Gwang-Hoon),류병재(Ryu, Byong-Jae),유동근(Yoo, Dong-Geun),정부흥(Chung, Bu-Heung),강년건(Kang, Nyeon-Keon) 한국신재생에너지학회 2009 한국신재생에너지학회 학술대회논문집 Vol.2009 No.06

The bottom-simulating reflector (BSR) is the most commonly observed seismic indicator of gas hydrate in the Ulleung Basin, East Sea. We processed ten representative seismic reflection profiles, selected from a large data set, for amplitude variation with offset (AVO) analysis of the BSR to estimate gas-hydrate concentrations. First, BSRs were divided into five groups based on their seismic amplitudes and associated sediment types: (1) very high-amplitude BSRs in turbidite/hemipelagic sediments, (2) high-amplitude BSRs in debris-flow deposits, (3) moderate-amplitude BSRs in turbidite/hemipelagic sediments, (4) very low-amplitude BSRs in debris-flow deposits, and (5) very low-amplitude BSRs in seismic chimneys. The AVO responses of the group 1 and 3 BSRs are characterized by a rapid decrease and a relatively slow decrease in magnitude with offset, respectively. The AVO response of the group 2 BSR is characterized by a relatively slow increase in magnitude with offset. The AVO responses of the groups 4 and 5 BSRs are characterized by a flat AVO with very small zero-offset amplitude. Theoretical AVO curves, based on the three-phase Biot theory, suggest that the group 1 and 3 BSRs may be related to high (> 40%) concentrations of gas hydrate whereas the group 2 BSRs may indicate low (< 20%) concentrations of gas hydrate. The AVO responses of the group 4 and 5 BSRs cannot be compared with the theoretical models because of their very small zero-offset amplitudes. The comparison of the AVO response of the BSR at the UBGH-04 well with theoretical models suggests about 10% gas-hydrate concentration above the gas-hydrate stability zone.

동해 가스하이드레이트 퇴적상 해석 및 분해능 향상을 위한 디컨볼루션 연구

이보연 ( Bo Yeon Yi ),이광훈 ( Gwang Hoon Lee ),김한준 ( Han Joon Kim ),정갑식 ( Caop Sik Jeong ),유동근 ( Dong Geun Yoo ),류병재 ( Byoung Jae Ryu ),강년건 ( Nyeon Keon Kang ) 한국지구물리탐사학회 2010 지구물리와 물리탐사 Vol.13 No.4

동해 울릉분지에서 가스하이드레이트 탐사를 목적으로 획득된 탄성파 중합 자료에 다음 세 가지의 디컨볼루션을 적용하여 지층경계면을 분해하는 특성을 분석하였다: (1) 트레이스별 최소위상 스파이킹 디컨볼루션 (2) 트레이스 평균 최소위상 디컨볼루션 (3) 검층자료를 이용한 디컨볼루션 트레이스벌 최소위상 스파이킹 디컨볼루션의 경우 수직 분해능은 증가하지만 수평 연장성이 감소하는 경향을 보였다. 각 트레이스에서 구한 최소위상 파형요소를 평균하여 구한 대표 파형요소를 이용하는 두 번째 방법은 전체적으로 트레이스별 스파이킹 디컨볼루션의 결과와 비슷해만 해저면 모방 반사 면이 보다 연속적이고 일관된 결과를 보이며 하부 반사면들이 더 뚜렷하게 나타난다. 세 번째 방법의 결과는 쇄설류 퇴적체 내부가 좀 더 상세하게 나타나며 해저연파 해저면 모방 반사면의 파형이 이상적 영위상 형태를 보이며 반사연의 연속성이 향상되었음을 보여준다. 이러한 특성은 가스하이드레이트 안정영역의 하부경계를 지시하는 해저면 모방 반사변의 진폭특성분적과 퇴적상 해석을 향상시키므로 탐사 지역의 가스하이드레이트 분포와 자원량을 정확히 추정하는 데에 도움을 준다. Three deconvolution methods were applied to stacked seismic data obtained to investigate gas-hydrates in the Ulleung Basin, East Sea: (I) minimum-phase spiking deconvolution, (2) minimum-phase spiking deconvolution using an averaged wavelet from all traces, and (3) deterministic deconvolution using a wavelet with phases computed from well- logs. We analyzed the resolving property of these methods fbr lithological boundaries. The first deconvolution method increases temporal resolution but decreases lateral continuity. The second method shows, in an overall sense, similar results to the spiking deconvolution using a minimum phase wavelet for each trace; however, it results in a more consistent and continuous bottom-simulating reflector (BSR) and better resolved sub-BSR reflectors. The results from the third method reveal more detailed internal structures of debris-flow deposits and increased continuity of reflectors; in addition, the seafloor reflection and the BSR appear to have changed to a zero-phase waveform. These properties help more precisely estimate the distribution and reserves of gas hydrates in the exploration area by improving analysis of f?eies and amplitude of the BSR.

사회불안에 대한 국내 연구동향 : 2001년부터 2018년을 중심으로

이보연(Bo Yeon Yi) 단국대학교 상담학연구소 2019 상담교육연구 Vol.2 No.1

본 연구는 2001년부터 2018년까지 국내 사회불안에 관한 동향을 규명하기 위해 수행되었다. KCI 등재지에 게재된 논문 57편을 최종 분석 대상으로 선정하여 연구년도, 대상, 척도, 변인을 기준으로 분석하였다. 주요 결과는 다음과 같다. 2011년까지 매년 1편에서 2편의 논문이 발표되었고, 2012년부터 2018년까지 5편부터 10편까지 많은 논문이 발표되어 이전 년도들에 비해 사회불안에 대한 연구가 활발히 연구되고 있음을 확인할 수 있었다. 연구대상은 사회불안이 초기 청소년기부터 초기 성인기에 발생한다는 선행연구결과를 토대로 초등학생 5, 6학년에서 대학생까지 다양한 연령층이 연구대상으로 선정되었고, 대학생 연구대상이 35편으로 가장 많았다. 척도는 사회불안의 질적인 특성에 따른 상호작용불안과 수행불안에 대한 개별척도를 합하여 측정되는 경우가 많았고, 연령에 따라 사회불안의 조작적 정의에 따라 다양한 척도들이 사용되었다. 변인별 동향에서는 사회불안이 종속변인으로 가장 많이 연구되고 있었으며, 사회불안이 종속변인 경우 독립변인을 인지, 정서, 행동, 환경으로 나누어 살펴보았다. 위의 결과를 토대로 본 연구의 한계점과 후속연구에 대한 제언을 하였다. Objectives: This study is a trend study on social anxiety in South Korea from 2001 to 2018. Methods: Fifty-seven papers published in KCI were selected for final analysis and analyzed based on the research year, subject, scale, and variables. Results: By 2011, one to two papers were published every year, and five to ten were published from 2012 to 2018, confirming that studies on social anxiety have been active compared to previous years. Based on the previous study, social anxiety occurred from early adolescence to early adulthood, students from fifth and sixth graders to college students were selected as the subjects of study, with the highest number of students being studied by 35. Scales were often used in combination with each individual measure of interaction anxiety and performance anxiety according to the contextual nature of social anxiety, and with age various measures were used according to the operational definition of social anxiety. In the trend by variables, social anxiety was studied most often as a dependent variable, the independent variable was looked at as a cognition, emotion, behavior, temperament, and environment. Conclusions: Based on the above results, I would like to propose the limitations of this study and future studies on social anxiety.

Overproduction of recombinant endoxylanase by sequential genome integration in Saccharomyces cerevisiae

Bo-Hyun KIM,Soo-Wan NAM,Yeon-Hee KIM,Yi-Joon KIM,Kwang-Hee SON,Ho-Yong PARK 한국생물공학회 2013 한국생물공학회 학술대회 Vol.2013 No.4

Food Science/Microbiology : Article ; Temperature Dependent Growth Characteristics and a Predictive Mathematical Model of Salmonella enterica serovar Typhimurium in Kimbab

( Bo Yeon Kim ),( Song Yi Choi ),( Kyo Young Seo ),( Sang Do Ha ) 한국응용생명화학회(구 한국농화학회) 2011 Applied Biological Chemistry (Appl Biol Chem) Vol.54 No.3

The growth characteristics of Salmonella enterica serovar Typhimurium (S. Typhimurium) were evaluate for development of a polynomial model to predict the growth rates and lag time of S. Typhimurium in Kimbab as a function of temperature (5, 10, 20, 30, and 40˚C). In all experimental variables, the primary growth curves fit well (r2=0.9071 to 0.9998). The predicted growth rates of S. Typhimurium generally decreased at lower temperature (10˚C) and increased at high temperature (30, 40˚C). In addition, the predicted lag times of S. Typhimurium generally decreased at high temperature (30, 40˚C) and increased at low temperature (10˚C). Results showed the polynomial model developed in the present study is an appropriate secondary model for determing growth rates and lag time on the basis of the correlation of coefficient (r2=0.9688 for specific growth rate (SGR), 0.9369 for lag time (LT)), coefficient of determination (r2=0.9138 for SGR, 0.8901 for LT), mean square error (mean square error (MSE)=0.0003 for SGR, 0.0417 for LT), bias factor (Bf=0.9936 for SGR, 0.8126 for LT) and accuracy factor (Af=1.0741 for SGR, 1.2834 for LT). Therefore, this secondary model was shown to reliably predict the maximum growth rates and lag times for S. Typhimurium in Kimbab.

가소화 전분필름의 강도 및 열적 성질에 미치는 나노셀룰로오스 및 아민화전분의 첨가영향

김보연 ( Bo Yeon Kim ),한송이 ( Song Yi Han ),이선영 ( Sung Yong Lee ),김영균 ( Young Kyoon Kim ),김남훈 ( Nam Hun Kim ),이승환 ( Seung Hwan Lee ) 한국목재공학회 2014 목재공학 Vol.42 No.4

본 연구는 가소화 전분필름의 열적 및 강도적 성질에 미치는 두 종류의 나노셀룰로오스, 즉 마이크로피브릴 셀룰로 오스(MFC)와 셀룰로오스 나노크리스탈(CNC) 및 아민화전분의 첨가영향을 조사하였다. 글리세롤(23 wt%)을 전분의 가소제로 사용하였으며, 나노셀룰로오스를 각각 1, 5, 10, 30 중량부(phr)를 첨가하여 나노필름을 제조하였다. 나노셀룰로오스의 첨가량이 증가함에 따라 인장강도 및 탄성율은 비례적으로 증가하였으나 신장율은 저하하였다. 또한, MFC 강화필름의 강도적 성질이 CNC 강화필름보다 큰 값을 나타냈다. 제지용 사이즈제로 사용하는 아민화전분의 소량 첨가는 강도적 성질의 향상에 양호한 영향을 미쳤다. MFC 강화 전분나노필름의 TGA에 의한 열적 안정성은 MFC (30phr)의 첨가에 의하여 향상되었으며, 아민화전분 첨가 나노필름의 경우에도 MFC를 첨가함으로써 향상되었다. This study investigated the effect of nanocellulose, such as microfibrillated cellulose (MFC) and cellulose nanocrystal(CNC), and aminated starch on tensile property and thermal stability of plasticized starch film. Glycerol (23 wt%) was used as a plasticizer and nanocelluloses of 1-30 parts per hundred parts of resin (phr) in the basis of plasticized starch were added. Tensile strength and elastic modulus increased with increasing nanocellulose addition amount, whereas elongation at break decreased. Tensile properties of MFC-reinforced starch film were higher than those of CNC-reinforced film. Optimum addition amount of aminated starch, which is commonly used for paper sizing, to improve tensile property of film, was found to be 5%. And 1% addition of aminated starch showed the best effect in the improvement of tensile property of the film. Thermal stability was improved with the addition of MFC to plasticized starch film with and without aminated starch.

Utility and Diagnostic Performance of Automated Breast Ultrasound System in Evaluating Pure Non-Mass Enhancement on Breast Magnetic Resonance Imaging

Kwon Bo Ra,Chang Jung Min,Kim Soo-Yeon,Lee Su Hyun,Shin Sung Ui,Yi Ann,Cho Nariya,Moon Woo Kyung 대한영상의학회 2020 Korean Journal of Radiology Vol.21 No.11

Objective: To compare the utility and diagnostic performance of automated breast ultrasound system (ABUS) with that of handheld ultrasound (HHUS) in evaluating pure non-mass enhancement (NME) lesions on breast magnetic resonance imaging (MRI). Materials and Methods: One hundred twenty-six consecutive MRI-visible pure NME lesions of 122 patients with breast cancer were assessed from April 2016 to March 2017. Two radiologists reviewed the preoperative breast MRI, ABUS, and HHUS images along with mammography (MG) findings. The NME correlation rate and diagnostic performance of ABUS were compared with that of HHUS, and the imaging features associated with ABUS visibility were analyzed. Results: Among 126 pure NME lesions, 100 (79.4%) were malignant and 26 (20.6%) were benign. The overall correlation rate was 87.3% (110/126) in ABUS and 92.9% (117/126) in HHUS. The sensitivity and specificity were 87% and 50% for ABUS and 92% and 42.3% for HHUS, respectively, with no significant differences (p = 0.180 and 0.727, respectively). Malignant NME was more frequently visualized than benign NME lesions on ABUS (93% vs. 65.4%, p = 0.001). Significant factors associated with the visibility of ABUS were the size of NME lesions on MRI (p < 0.001), their distribution pattern (p < 0.001), and microcalcifications on MG (p = 0.027). Conclusion: ABUS evaluation of pure NME lesions on MRI in patients with breast cancer is a useful technique with high visibility, especially in malignant lesions. The diagnostic performance of ABUS was comparable with that of conventional HHUS in evaluating NME lesions.