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설계방식과 주거질 지표에 따른 공동주택 계획기준 개선연구 : 현상설계방식을 중심으로 Focused on Design Competition Method
배웅규,정종대,김원필 대한건축학회 2005 대한건축학회논문집 Vol.21 No.3
This study is aimed at evaluating the current multi-family housing projects under the site planning criteria by examining its application and design process to improve the current criteria. In order to assess the application of the current site planning criteria, two competition schematic designs were compared each other on the same land area. The research found that facilities such as retail shop, security posts, maintenance office, nurseries and libraries were not provided according to the current site planning criteria. In addition, it showed that parking lots and other community facilities did not follow the current site planning criteria but rather changed based upon individual needs. When evaluating the criteria in lieu of the number of residents and unit size, the study found that a block with more residents and smaller unit size (block A) less stringently adhered to the site planning criteria, comparing with a block that has larger unit size and less residents (block B). In order to strengthen the current site planning criteria, seven quality indicators were examined for the evaluation of the competition schematic design by per floor space and per housing unit, verifying that good design also scored well on every quality index. It was also maintained that the need to review the current criteria scope of resident and unit size, along with module size was important for the qualitative housing design.
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( Dae Geon Ahn ),( Hyung Joon Kim ),( Hyun Woong Lee ),( Si Hyun Bae ),( Joon Hyeok Lee ),( Yong Han Paik ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.-
Background: Recent systematic reviews show that the quality of evidence supporting the use of AFP as a diagnostic and screening test for hepatocellular carcinoma (HCC) is limited. The Korean Liver Cancer Study Group recommended the cutoff value of 200ng/mL as a diagnostic tool. The aim of this study was to evaluate the feasibility of AFP as a screening and and to explore the optimal level of AFP for HCC diagnosis Methods: We retrospectively reviewed the medical records of HCC (all cases were biopsy proven) and cirrhosis patient have available data in 3 hospitals. A total of 1,560 patients were classified into three groups: 564 were cirrhosis controls, 766 were patient with early stage HCC (n = 123 very early, n = 643 early) and 230 were patient with late stage HCC. The performance of AFP in three groups was compared with each other. The AFP sensitivity, specificity, positive and negative predictive values were calculated. Results: The mean age was 54 years in cases, and 56 years in control. Male was dominant in both groups (case, 81.1% vs. control, 65.7%). The mean AFP was significantly higher in patients with overall HCC (early, late) than in those with liver cirrhosis. [early HCC, 2,769ng/ml (1-200,000) , late HCC, 9,818ng/ml (1-639,100), control, 20ng/ml (0.61-1,753)]. (p< 0.0001) Area under the receiver operating characteristic curve for those overall HCC with cirrhosis is 0.78. The sensitivity, specificity, and PPV of AFP was 52.6%, 87.7%, 88.3% at a cutoff of 20ng/ml; 36.9%, 95.9%, 94.1% at a cutoff of 100ng/ml and 29.5%, 98.0%, 96.3% at a cutoff of 200 ng/ml. As a screening tool for HCC , a cutoff of 100ng/ml is more sensitive than 200 ng/ml with equivalent specificity and PPV. The optimal AFP cutoff value was 8.2ng/ml leading to a sensitivity of 66.9% and a specificity of 75.7%. Conclusions: Our study cautiously suggested that the optimal value of AFP in the diagnosis of HCC might be switched 200 ng/ml to 100ng/ml.
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Urban webs: analyzing spider diversity and ecological dynamics in urban habitats
Dae-Hee Kim,Woong-Bae Park,Yuno Do 한국응용곤충학회 2024 한국응용곤충학회 학술대회논문집 Vol.2024 No.04
This study investigated the distribution and diversity of spider communities living in natural and semi-natural environments located in Gongju, Chungcheongnam-do, South Korea, and thereby emphasizes the importance of urban planning and biodiversity conservation. In this study, we documented 128 spider species through pit-fall trapping, sweeping, and manual collection methods and analyzed their alpha and beta diversity, nestedness, and interactions. As a result, natural habitats (forests) showed higher biodiversity and more complex species interactions. Despite anthropogenic impacts, such as human activities, urban habitats have shown notable biodiversity. Nestedness analysis and association rule learning reveal diverse community structures in multiple habitats and intricate interspecies relationships. This study highlights the importance of habitat heterogeneity in supporting biodiversity and the importance of considering multiple ecological factors in urban planning.
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Efficient Phosphinothricin Mediated Selection of Callus Derived from Brachypodium Mature Seed
Woong Bae Jeon,Man Bo Lee,Dae Yeon Kim,Min Jeong Hong,Yong Jin Lee,Yong Weon Seo 한국육종학회 2010 한국육종학회지 Vol.42 No.4
Brachypodium distachyon is rapidly emerged in biological study and has been currently used as a model system for genetics and functional studies for crop improvement and biofuel production. Phosphinothricin (PPT) has been widely used as a selectable agent, which raises ammonium content and induces toxicity in non-transformed plant cells. However PPT selection is not much effective on Brachypodium callus consequently reducing transformation efficiency. In order to identify the efficient conditions of PPT selection, calli obtained from mature seeds of Brachypodium (PI 254867) were cultured on the callus inducing medium (CIM) or regeneration medium (ReM) containing serial dilutions of the PPT (0, 2, 5, 10, and 15 mg/l) in dark or light condition. Callus growth and ammonium content of each treatment were measured 2 weeks after the treatment. Although callus growth and ammonium content did not show much difference in CIM, slow callus growth and increased ammonium accumulation were found in ReM. No significant difference of ammonium accumulation in response to PPT was found between dark and light conditions. In order to identify major factors affecting increased ammonium accumulation, callus was cultured on the media in combined with phytohormones (2,4-D or kinetin) and carbon sources (sucrose or maltose) containing with PPT (5 mg/l). The highest ammonium content in callus was found in the kinetin and maltose media.
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Influence of micro-environmental factors on decomposition and insect colonization
Woong-Bae Park,Siae Park,Dae-Hee Kim,Yuno Do 한국응용곤충학회 2024 한국응용곤충학회 학술대회논문집 Vol.2024 No.04
This study explores the significant influence of micro-environmental factors on carcass decomposition and insect colonization, with a particular emphasis on detailed insect community analysis. The research employed an innovative approach by placing two pig carcasses in contrasting environments that one in a sunlit open field and the other in a shaded forest. The findings revealed dynamic shifts in insect diversity in the sunlit area, characterized by a rapid increase followed by a decrease, in contrast to the more steady, gradual changes observed in the shaded area. This contrast highlights the sensitivity of insect communities to even minor changes in environmental conditions like sunlight and temperature. It unveils the nuanced ways in which such factors shape the composition and dynamics of insect communities. These insights are crucial for the field of forensic entomology, enhancing the accuracy of post-mortem interval estimations. By providing a clearer understanding of how different micro-environmental conditions influence insect activity and decomposition processes, this study significantly contributes to the refinement of forensic methodologies.
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( Dae Geon Ahn ),( Hyung Joon Kim ),( Hyun Woong Lee ),( Si Hyun Bae ),( Joon Hyeok Lee ),( Yong Han Paik ) 대한간학회 2012 춘·추계 학술대회 (KASL) Vol.2012 No.1
Background: Recent systematic reviews show that the quality of evidence supporting the use of AFP as a diagnostic and screening test for hepatocellular carcinoma (HCC) is limited. The Korean Liver Cancer Study Group recommended the cutoff value of 200ng/mL as a diagnostic tool. The aim of this study was to evaluate the feasibility of AFP as a screening and and to explore the optimal level of AFP for HCC diagnosis Methods: We retrospectively reviewed the medical records of HCC (all cases were biopsy proven) and cirrhosis patient have available data in 3 hospitals. A total of 1,560 patients were classified into three groups: 564 were cirrhosis controls, 766 were patient with early stage HCC (n = 123 very early, n = 643 early) and 230 were patient with late stage HCC. The performance of AFP in three groups was compared with each other. The AFP sensitivity, specificity, positive and negative predictive values were calculated. Results: The mean age was 54 years in cases, and 56 years in control. Male was dominant in both groups (case, 81.1% vs. control, 65.7%). The mean AFP was significantly higher in patients with overall HCC (early, late) than in those with liver cirrhosis. [early HCC, 2,769ng/ml (1-200,000) , late HCC, 9,818ng/ml (1-639,100), control, 20ng/ml (0.61-1,753)]. (p< 0.0001) Area under the receiver operating characteristic curve for those overall HCC with cirrhosis is 0.78. The sensitivity, specificity, and PPV of AFP was 52.6%, 87.7%, 88.3% at a cutoff of 20ng/ml; 36.9%, 95.9%, 94.1% at a cutoff of 100ng/ml and 29.5%, 98.0%, 96.3% at a cutoff of 200 ng/ml. As a screening tool for HCC , a cutoff of 100ng/ml is more sensitive than 200 ng/ml with equivalent specificity and PPV. The optimal AFP cutoff value was 8.2ng/ml leading to a sensitivity of 66.9% and a specificity of 75.7%. Conclusions: Our study cautiously suggested that the optimal value of AFP in the diagnosis of HCC might be switched 200 ng/ml to 100ng/ml.
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Feasibility of α-fetoprotein as a diagnostic tool for hepatocellular carcinoma in Korea
( Dae Geon Ahn ),( Hyung Joon Kim ),( Hyun Kang ),( Hyun Woong Lee ),( Si Hyun Bae ),( Joon Hyoek Lee ),( Yong Han Paik ),( June Sung Lee ) 대한내과학회 2016 The Korean Journal of Internal Medicine Vol.31 No.1
Background/Aims: The aim of this study was to evaluate the feasibility of α-fetoprotein (AFP) as a diagnostic tool for hepatocellular carcinoma (HCC) in Korean patients. Methods: We retrospectively reviewed the medical records of HCC and cirrhosis patients at three hospitals. For each HCC patient, a cirrhosis patient matched for age, sex, etiology, and Child-Pugh classification was selected by simple random sampling. The performance of AFP in the diagnosis of HCC was determined using receiver operating characteristic curve analysis. Results: A total of 732 patients with HCC or cirrhosis were selected for each case and the control groups. The mean age was 54 years, and 72.4% of patients were male. The mean serum AFP levels in the HCC group and cirrhosis group were 3,315.6 and 117.2 ng/mL, respectively (p < 0.001). The area under the receiver operating characteristic curve for all HCC patients was 0.757. The sensitivity, specificity, and positive predictive value of AFP was 50.55%, 87.70%, and 80.43%, respectively, at a cut-off of 20 ng/mL; 37.70%, 95.90%, and 90.20%, respectively, at a cut-off of 100 ng/mL, and 30.05%, 97.27%, and 91.67%, respectively, at a cut-off of 200 ng/mL. A cut-off of 100 ng/mL was more sensitive than one of 200 ng/mL with equivalent specificity and positive predictive value. Conclusions: The cut-off AFP value for early-stage HCC was 17.4 ng/mL. Our study cautiously suggests that AFP has a role in the diagnosis of HCC, and that the appropriate value of AFP for the diagnosis of HCC may be 100 ng/mL rather than 200 ng/mL.
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