유한 요소 모형을 이용한 어린이의 머리 충격 부상에 관한 연구

김영은,남대훈,왕규창 한국산업안전학회 1997 한국안전학회지 Vol.12 No.4

The dynamic response of the human brain to direct impact was studied by three-dimensional finite element modeling. The model includes a layered shell closely representing the cranial bones with the interior contents occupied by an incompressible continuum to simulate the brain. Falx and tentorium modeled with 4 node membrane element were also incorporated. The computed pressure-time histories at 4 locations within the brain element compared quite favorably with previously published experimental data from cadaver experiments. Therefore, the purpose of this study was to determine the effects of the impact direction on the dynamic response of the brain in children. A parametric study was subsequently conducted to identify the model response when the age and impact site were varied.

New Species and New Records of Buellia (Lichenized Ascomycetes) from Jeju Province, South Korea

Wang, Xin Yu,Liu, Dong,Lokos, Laszlo,Kondratyuk, Sergey Y.,Oh, Soon-Ok,Park, Jung Shin,Hur, Jae-Seoun The Korean Society of Mycology 2016 Mycobiology Vol.44 No.1

A new species and 2 new records of lichen genus Buellia were discovered from Chuja-do Island in Jeju Province during a recent floristic survey: B. chujana X. Y. Wang, S. Y. Kondr., L. $L\ddot{o}k\ddot{o}s$ & J.-S. Hur sp. nov., B. halonia (Ach.) Tuck., and B. mamillana (Tuck.) W. A. Weber. The new species is characterized by a brown, areolate thallus, the presence of perlatolic acid, and a saxicolous habitat. Together with previously recorded species, 10 Buellia species were confirmed from Jeju-do Island. Among these species, 3 growing in the exposed rocky area contained xanthone (yellowish lichen thallus, UV + orange), indicating that production of xanthone in this genus might be a defense strategy against the harm of UV light. Although the genus Buellia has been thoroughly studied in Korea before, novel species have been discovered continuously, and large species diversity has been found in this crustose genus, even from a small rocky island. This study indicates that the coastal area harbors a vast number of crustose lichen species, and there is great potential to discover unknown lichens in the coastal rocky area in Korea.

High temperature cyclic oxidation behavior of Y2O3-ZrO2 thermal barrier coatings irradiated by high-intensity pulsed ion beam

Wang, Y. q.,Lei, M. k.,Afsar, A. M.,Song, J. I. Springer Science + Business Media 2009 JOURNAL OF CENTRAL SOUTH UNIVERSITY OF TECHNOLOGY Vol.16 No.1

MOVING

KIM YŎNGHA,JENNY WANG MEDINA 계명대학교 한국학연구원 2006 Acta Koreana Vol.9 No.2

Kim Yŏngha was born in Seoul in 1968 and studied at Yonsei University and the International Writers Workshop at the University of Iowa. He debuted on the literary scene in 1995 with the short story “Kŏul e taehan myŏngsang” (Meditation on a mirror), and is widely acclaimed as one of the best young writers in Korea today, noted for his imaginative story-telling and lively narrative style. His first novel, Na nŭn na rŭl p’agoehal kwŏlli ka itta (1996, I have the right to destroy myself), earned him the Munhaktongne New Writer Award, and in 2004, he was awarded both the Yi Sang Prize for Literature and the Hwang Sunwŏn Prize for Literature for his collection of short stories, Oppa ka torawatta. In addition to fiction, Kim is also the author of many essays and film reviews, the host of a radio program about literature, and most recently, a screenwriter. In “Moving,” first published in 2004, Kim treats the story of a young couple’s move with his characteristic sympathetic irony, touching on issues of class, the com-modification of Korean history, and the questionable nature of the idea of “home.”

Formation of Y2O3 nanodots on substrate surface using the rf-sputtering method

K. C. Chung,J. M. Yoo,Y. K. Kim,X. L. Wang,S. X. Dou 한국초전도저온학회 (구 한국초전도저온공학회) 2008 한국초전도저온공학회논문지 Vol.10 No.4

A Phase 3 Evaluation of Daclatasvir plus Asunaprevir in Treatment-Naive Patients with Chronic HCV Genotype 1b Infection

( L. Wei ),( F. Wang ),( M. Zhang ),( J. Jia ),( A.A. Yakovlev ),( W. Xie ),( E.Z. Burnevich ),( J. Niu ),( Y.J. Jung ),( X. Jiang ),( M. Xu ),( X. Chen ),( Q. Xie ),( J. Li ),( J. Hou ),( H. Tang ),( 대한간학회 2017 춘·추계 학술대회 (KASL) Vol.2017 No.1

Background/Aims: Treatment-naive GT 1b-infected patients from mainland China, South Korea and Russia were assessed for SVR at follow-up week 12 (SVR12) after receiving daclatasvir (60 mg, QD) and asunaprevir (100 mg, BID) (DCV+ASV). Methods: Patients were randomized 3:1 to receive DCV+ASV (24 weeks; immediate treatment [IM]) or 12 weeks of placebo followed by DCV+ASV (24 weeks; placebo-deferred treatment [PD]). The primary endpoint was to evaluate SVR12 in the IM arm to the historical rate for peginterferon/ribavirin (70%). Secondary endpoints included overall safety and safety comparisons between the treatment arms during the first 12 weeks. Results: 207 patients were randomized to IM (n=155) or PD (n=52); Asian (86%), female (59%), IL28B CC genotype (68%) and median age 49 (range 18-73) years; cirrhosis (13%), HCV RNA ≥6x106 IU/mL (53%). SVR12 in the IM arm was 92% and broadly unaffected by most baseline factors assessed (Figure); SVR12 was higher in patients without (96%) baseline NS5A-L31M/V or Y93H polymorphisms. There were 6 virologic breakthroughs, 6 relapses and 1 detectable HCV RNA at end-of-treatment in the IM arm. Safety was mostly comparable between the two arms during the first 12 weeks. The most frequent adverse events (AEs; ≥5%) during DCV+ASV (24 weeks) treatment in both arms were aminotransferase, bilirubin and INR elevations, hypertension, fatigue and respiratory tract infections; the most frequent treatment-emergent grade 3/4 laboratory abnormalities were aminotransferase (≤4.5%) and hematologic, lipase and total bilirubin abnormalities (≤2%); one patient (IM) discontinued DCV+ASV for aminotransferase elevations, nausea and jaundice (all reversible); one patient PD) discontinued DCV+ASV for a fatal AE unrelated to treatment. Conclusions: These data demonstrate that DCV+ASV is a highly efficacious and well tolerated treatment for treatment-naive HCV GT 1b-infected patients. Those treated immediately with DCV+ASV achieved a 92% SVR12 rate which was unaffected by factors known to attenuate response to interferon.

Thermoelectric properties of Gd, Y co-doped Ca3Co4O9+δ

H.Q. Liu,X.B. Zhao,T.J. Zhu,Y. Song,F.P. Wang 한국물리학회 2009 Current Applied Physics Vol.9 No.3

The Ca3-x-yGdxYyCo4O9+δ precursor powders were synthesized by the polyacrylamide gel method. The powders were sintered by the spark plasma sintering (SPS). The DTA analysis showed that the synthesis temperature of Ca3Co4O9+δ was about 933 K, which is lower than that of the conventional citric acid method. The resistivities, the Seebeck coefficients and the thermal conductivities of the samples were measured from room temperature to 973 K. The Seebeck coefficients and the resistivities of the doped samples were remarkably enhanced due to the decrease of the carrier concentration, whereas the thermal conductivities of them were decreased due to the impurity scattering effect. The maximal ZT value of 0.26 was obtained at 973 K for Ca2.7 Gd0.15 Y0.15Co4O9+δ. The Ca3-x-yGdxYyCo4O9+δ precursor powders were synthesized by the polyacrylamide gel method. The powders were sintered by the spark plasma sintering (SPS). The DTA analysis showed that the synthesis temperature of Ca3Co4O9+δ was about 933 K, which is lower than that of the conventional citric acid method. The resistivities, the Seebeck coefficients and the thermal conductivities of the samples were measured from room temperature to 973 K. The Seebeck coefficients and the resistivities of the doped samples were remarkably enhanced due to the decrease of the carrier concentration, whereas the thermal conductivities of them were decreased due to the impurity scattering effect. The maximal ZT value of 0.26 was obtained at 973 K for Ca2.7 Gd0.15 Y0.15Co4O9+δ.

Cyclic Oxidation Behavior of Thermal Barrier Coatings Irradiated by High-intensity Pulsed Ion Beam

J. I. Song(송정일),Y. Q. Wang(왕일기),Y. G. Kwun(권용구),W. K. JOO(주원경) 한국자동차공학회 2007 한국자동차공학회 춘 추계 학술대회 논문집 Vol.- No.-

High-temperature oxidation resistance of 7 wt. % Y₂O₃-ZrO₂ thermal barrier coatings (TBCs) irradiated by high-intensity pulsed ion beam (HIPIB) has been investigated in a cyclic oxidation condition at 1050 ℃×1 h. The characteristics of the columnar grains disappeared after HIPIB irradiation at the ion current densities of 100-200 A/㎠, and the irradiated surface presented a smoothed, densified feature after the remelting and ablation due to the HIPIB irradiation. The cross-sectional morphologies of HIPIB-irradiated TBCs show less oxidation of the NiCoCrAlY bonding layer, with a thinner thermally grown oxide (TGO) layer. The morphology observation is consistent with the results of cyclic oxidation test. It is found that the inward diffusion of oxygen through TBCs can be significantly impeded by the desified top layer by the HIPIB irradiation, thus limiting the oxidation of the bonding layer, improving the overall oxidation resistance of the irradiated TBCs.

Genetic polymorphism in pvmdr1 and pvcrt-o genes in relation to in vitro drug susceptibility of Plasmodium vivax isolates from malaria-endemic countries

Lu, F.,Lim, C.S.,Nam, D.H.,Kim, K.,Lin, K.,Kim, T.S.,Lee, H.W.,Chen, J.H.,Wang, Y.,Sattabongkot, J.,Han, E.T. Verlag für Recht und Gesellschaft ; Elsevier 2011 Acta Tropica Vol.117 No.2

Treatment failure of chloroquine for Plasmodium vivax infection has increased in endemic countries. However, the molecular mechanisms for resistance and in vitro susceptibility of P. vivax to chloroquine remain elusive. We investigated the prevalence of mutations in the pvmdr1 and pvcrt-o genes, and the copy number of the pvmdr1 gene in isolates from the Republic of Korea (ROK), Thailand, the Union of Myanmar (Myanmar), and Papua New Guinea (PNG). We also measured in vitro susceptibility of Korean isolates to antimalarial drugs. The pvmdr1 analysis showed that mutations at amino acid position Y976F of pvmdr1 were found in isolates from Thailand (17.9%), Myanmar (13.3%), and PNG (100%), but none from the ROK, and mutation at position F1076L was present in isolates from the ROK (100%), Thailand (60.7%), and Myanmar (46.7%). One copy of the pvmdr1 gene was observed in most isolates and double copy numbers of the gene were observed in two Thai isolates. In the exons of the pvcrt-o gene that were sequenced, a K10 insertion was present in isolates from Thailand (56.0%) and Myanmar (46.2%), and the wild type was found in all Korean isolates. The results suggest that gene polymorphisms and copy number variation was observed in isolates of P. vivax from Southeast Asian countries. In Korean isolates polymorphism as limited to the F1076L variant, and no isolates with high level of resistance were found by in vitro susceptibility determinations. Moreover, our results provide a baseline for future prospective drug studies in malaria-endemic areas.

Fabrications and dielectric performances of novel composites: Calcium copper titanate / Polyvinylidene fluoride

Wang J.J.,Deng Q.J.,He Y.Y.,Feng Y.N.,Kang M.P.,Duan X.L.,Yang Y.L. 한국물리학회 2022 Current Applied Physics Vol.39 No.-

CCTO (Calcium copper titanate) powder as inorganic filler was synthesized by the Sol-gel method firstly. CCTO/ PVDF (Polyvinylidene fluoride) composite was fabricated by solution mixing based on high temperature resistance of PVDF and insulated property of CCTO. The composite of CCTO/PVDF were characterized by X-ray diffraction, Fourier Transform infrared spectroscopy, Scanning Electron Microscope and impedance analysis. The results showed that the addition of CCTO and increasing in its content did not affect the phase- and microstructure of the composites,but the increase of CCTO content can induce the generation of C–F new bonds. PVDF/CCTO composites were enhanced in performance of thermal and frequency-depended stability with increasing in the fraction of CCTO. The dielectric constant of CCTO/PVDF composite materials with 50% CCTO achieved to a maximum value of 50 almost, which is 5 times higher the pure PVDF. The conductivity felled into 10-8 to 10-1 S m-1 during the frequency of 102–108 Hz. The composite material would be expected to be applied in the field of integrated circuit.