폐경 전 여성의 골감소증 관련요인

이명숙 ( Myeong Sook Lee ),강복수 ( Pock Soo Kang ),이경수 ( Kyeong Soo Lee ) 영남대학교 기초/임상의학연구소 2007 Yeungnam University Journal of Medicine Vol.24 No.2S

Purpose:The purpose of the study was to determine factors affecting bone mineral density among premenopausal women aged over 45 years old and make a contribution to preventing osteoporosis among postmenopausal women. Materials and Methods:A total of 133 women enrolled in the study and completed a self-administered questionnaire that measured results of bone mineral density exam and biochemical exam, demographic characteristics, smoking and drinking, physical activities and reproductive characteristics. Results:The results of the study are summarized as follows: Of total subjects, 20.2% showed a reduction on bone mineral density. Age was the most important factor predicting bone mineral density level. A frequent intake of meat rather than vegetables had a significant impact on bone mineral density. Women with a menstruation cycle shorter than 28 days showed significantly high bone mineral density. Multiple regression analysis revealed a correlation between age and risk of osteoporosis. The explainability for variables was 16%. Conclusion:It is necessary to develop programs designed to help women in their 30s to maintain the maximum bone density and prevent osteoporosis after menopause.

산삼 배양근이 함유된 두피토닉이 두피와 모발에 미치는 영향

이명숙 ( Myeong Sook Lee ),김미나 ( Mi Na Kim ) 한국미용학회 2015 한국미용학회지 Vol.21 No.2

This study aims to identify the effects of the use of wild ginseng extracts-contained scalp tonic on scalp and hair. It targets 21 subjects in their 20ties who are living in Busan and they are divided into 3 groups: M-Group(Massage Group) of 7 subjects with scalp massage, and MT-Group(Massage Tonic Group) of 7 subjects with scalp massage and scalp tonic, and C-Group(Comparison Group) of 7 subjects without scalp massage and scalp tonic. The experiment is performed once a week from May 7th, 2012 to June 29th, 2012 for 8 weeks. Their top and front portions are measured with a scalp diagnosis machine(HMD scalp diagnosis system, Borntech, Korea) in week 4 and 8. As a result, it is found in MT-Group that hair density improved by 14.6 hairs (p<.01) in their top and 18.4 hairs (p<.001) in their front in week 8 and hair thickness improved by 0.019 mm(p<.01) in their top and 0.021 mm(p<.001) in their front in week 8. When it comes to scalp condition, normal scalp increased by 50% in week 8 in MT-Group. The MT-Group who received scalp massage and scalp tonic containing wild ginseng extracts is found to be the most effective group in hair density, hair thickness and scalp condition. Therefore, it can be concluded that scalp tonic containing natural substance Wild Ginseng is very effective for scalp and hair improvement.

指定討論要旨

李明淑(Lee Myeong-Sook) 한국법학원 2002 저스티스 Vol.- No.65

Bacillus cereus菌의 增殖速度와 胞子의 耐熱性에 關한 硏究

李明淑(Myeong-Sook Lee),張東錫(Dong-Suck Chang) 한국식품과학회 1982 한국식품과학회지 Vol.14 No.1

영국의 직업교육과 훈련

이명숙(Myeong-sook Lee),강욱모(Wook-mo Kang) 경상대학교 사회과학연구원(사회과학연구) 1998 사회과학연구 Vol.16 No.1

유산균 발효에 관한 동력학적 연구(제2보) 발효에 미치는 온도의 영향

이근태,이명숙,한봉호,LEE Keun-Tai,LEE Myeong-Sook,HAN Bong-Ho 한국수산과학회 1979 한국수산과학회지 Vol.12 No.3

To know the influence of temperature on the fermentation process, a strain of Lactobacillus bulgarius was experimentally cultured three different temperature conditions of $39^{\circ}C,\;42^{\circ}C\;and\;45^{\circ}C$, pH 5.8 and mechanical agitation of 500rpm. During 20 hour's fermentation, the microbial growth attained the maximum concentration under the conditions mentioned above. However, the culturing conditions resulted different outcomes in terms of maximum concentration of the microbes and the residual concentration of substrate. Among the three temperature conditions, the fermentation at $45^{\circ}C$ was most effective and the maximum specific growth temperature conditions, the fermentation at $45^{\circ}C$ was most effective and the maximum specific growth rate was 0.58/hr. Activation energy deduced from the Arrhenius equation was 9,220cal/mole and entropy was $-33.74\;cal/^{\circ}K$ mole. Activation enthalpy was 9,845 cal/mole and free energy was 19,800 cal/mole. 유산균 식료공법에서 중요한 위치를 차지하는 L. bulgaricus의 배양온도에 의한 산소 효과 및 열역학적 고찰을 요약하면 다음과 같다. 1) L. bulgaricus를 20시간 배양시 균체는 최고농도에 달했고 배양온도 $39^{\circ}C,\;42^{\circ}C\;and\;45^{\circ}C$에서 각각 2.3UOD/ml, 2.6UOD/ml, 2.8UOD/ml로 나타났다. 2) 배양 30시간때 포도당 잔량은 배양온도 $39^{\circ}C,\;42^{\circ}C\;and\;45^{\circ}C$에서 각각 18.3g/l, 15.0g/l, 10.0g/l이었다. 3) 최대비증식속도는 배양온도, $39^{\circ}C,\;42^{\circ}C\;and\;45^{\circ}C$에서 각각 $0.42hr^{-1},\;0.48hr^{-1},\;0.58hr^{-1}$이었고 Saturation constant는 4.57mg/ml, 5.6mg/ml, 6.627mg/ml이었다. 5) 활성화 energy는 9,220cal/mol 배양온도의 변화에 따른 평균치로 활성화 entropy는 $-31.74cal/^{\circ}Kmol$, 반응열은 9,845cal/mol free energy는 19,800cal/mol이었다.

아로마 오일을 이용한 두피수기요법이 두피와 모발 상태에 미치는 영향

박수형 ( Su Hyeong Park ),이명숙 ( Myeong Sook Lee ) 대한미용학회 2012 대한미용학회지 Vol.8 No.4

The purpose of this study is to discover the effect of scalp manual technic using aroma oil on the scalp and hair, and to contribute to the prevention of hair loss and the improvement of scalp health. The study was conducted on 21 women who reside in the Busan and Gyeongnam areas. Seven women were in the AM-Group (Aroma Manual Technic Group) who received manual technic using aroma oil, seven in the M-Group (Manual Technic Group) who received manual technic only, and seven were in the CG (Control Group) with no action taken. The subjects were measured at the top, front, and back using a scalp diagnosis machine (HMD scalp diagnosis system, Borntech, Korea) before the experiment, four and eight weeks after the experiment. The hair density measurement showed that the M-Group had an average of 8% more density after the experiment compared to before the experiment, while the AM-Group showed a statistically significant average increase of 12% compared to before the experiment (p/. 01). The hair thickness measurement showed that the M-Group had an average increase of 9% compared to before the experiment (p/. 01). The AM-Group showed a 30% increase compared to before the experiment (p/. 001). In the scalp condition, the M-Group showed a 38.1% improvement compared to before the experiment while the AM-Group showed a 52.4% improvement, showing a clearer scalp tone. Therefore, the treatment of scalp manual technic using aroma oil has potential effect to improve scalp conditions and prevent or manage hair loss in young people.

농촌 전기노인과 후기노인의 건강행태와 건강상태

황성호(Seong Ho Hwang),이명숙(Myeong Sook Lee),이성국(Sung Kook Lee) 한국농촌의학 지역보건학회 2011 농촌의학·지역보건 Vol.36 No.4

본 연구는 노인이 하나의 동일한 성격을 가진 집단이 아니라 연령에 따라 다양한 경험과 세대 차이가 있는 하위 집단으로 이루어져 있다는 것을 전제로 하여 65~75세 미만의 전기노인과 75세 이상의 후기 노인들의 특성과 개인별 건강행태 특성, 그리고 현재의 건강상태 등을 비교하고자 하였다. 이를 위하여 상주시 관내 24개 읍ㆍ면ㆍ동 지역의 경로당 이용자 617명(전기노인 287명, 후기노인 330명)을 대상으로 설문 조사를 실시하고 실태를 비교분석한 결과는 다음과 같다. 인구사회학적 특성에 따른 결과는 남ㆍ여 모두 학력과 직업, 결혼상태, 동거가족에서 전ㆍ후기노인 간에 유의한 차이가 있었다. 주 3회 이상 10분 이상 걷기 횟수는 남자 후기노인이 전기노인에 비해서 유의하게 높았고 수면 시간은 남자와 여자노인 모두 전기노인의 수면시간이 후기노인에 비해서 유의하게 많았다. 질병 이환율은 여자 후기노인이 전기노인에 비해서 유의하게 높았고 제시한 16가지 계통의 질병중에서 남자 노인은 신경통ㆍ관절염이, 여자노인은 고혈압이 전기노인에 비해 후기노인의 이환율이 유의하게 높았다. 대상자의 생활수행능력은 경로당을 이용하는 건강한 노인이라는 특성이 반영되어 ADL(일상생활수행능력) 6개 항목을 모두 스스로 실천하는 응답자는 96.4%, IADL(수단적 일상생활능력) 6개 항목을 모두 실천하는 응답자는 90.8%로 매우 높게 나타났다. 건강상태에서 여자는 스트레스와 자살을 생각해본 경험이 후기노인이 전기노인에 비해 유의하게 많았고, 구강건강 상태와 청력, 시력은 남자와 여자 모두 전기노인이 후기노인에 비해서 유의하게 좋은 것으로 나타났다. 전ㆍ후기 노인의 건강행태와 건강상태에 대한 비교에서 남자는 주 3회 이상 10분 이상 걷기, 수면시간, 구강건강, 청력이, 여자는 수면시간, 스트레스, 청력, IADL이 유의한 변수로 분석되었다. 이상의 연구에서 후기 노인은 전기 노인에 비해서 인구사회학적인 특성에서 취약하며 이환된 질환의 수는 많았으나 규칙적으로 운동을 하는 노인은 적었다. 또한 신체활동능력과 정신건강 그리고 구강건강, 청력, 시력이 전기 노인에 비해서 좋지 못하였다. 따라서 후기노인에게 나타나는 신체적 정신적 건강의 취약성을 노화과정의 하나로만 볼 것이 아니라 연령층에 따라 나타나는 다양한 특성중의 하나라고 받아들이고 전ㆍ후기 노인들의 건강행태와 건강상태의 특성에 맞춘 다양한 질병예방, 건강 증진프로그램을 개발하고 적용할 수 있는 국가적 차원의 관리와 지원이 요구된다. Objectives: The purpose of this study is to garner useful information through a comparative analysis of health behaviors and health states between the young-old and old-old elderly in a rural Korean area. Methods: We define the young-old elderly as those 65 to 74 years of age, and the old-old as those over 70. The survey was administered in October and November of 2009 at senior citizen centers in Sangju City, Kyongsangbuk-do, South Korea. The number of subjects surveyed approximated the demographics of the aged population of the administrative district of centers of 24 eup, myeon, and dong. Results: Compared with the young-old elderly, the old-old were vulnerable to population sociological characteristics. While there were many cases of contraction of diseases, only a small percentage of old-old elderly were engaged in regular exercise. In addition, the old-old elderly lagged behind the young-old in terms of physical activity, mental and oral health, hearing, and vision. Conclusions: The vulnerability of the old-old elderly in terms of physical and mental health needs to be acknowledged as various characteristics of the elderly that appears according an age group. A variety of disease prevention and health promotion programs that focus on the health behavior and status of the young-old and old-old elderly need to be developed and put into practice.

女子中高等学生들의 食品營養知識 및 態度에 關한 調査

鄭文姬(Jung, Moon Hee),李明淑(Lee, Myeong Sook) 한국간호과학회 1980 Journal of Korean Academy of Nursing Vol.10 No.2

Protective Effects of Fucoidan against UVB-Induced Oxidative Stress in Human Skin Fibroblasts

Mi Jung Ku(구미정),Myeong Sook Lee(이명숙),Hee Jung Moon(문희정),Yong Hwan Lee(이용환) 한국생명과학회 2010 생명과학회지 Vol.20 No.1

자외선 B는 반응성 산소종(reactive oxygen species, ROS)의 발생을 유도하고 세포내 항산화 물질의 저장을 방해한다. 후코이단은 L-fucose와 황 에스터기를 포함하는 다당류로서 갈조류의 주요 성분으로 알려져 있다. 본 연구에서는 인간 피부 섬유아세포인 HS68세포에 자외선을 조사하여 산화 스트레스를 유도한 후 후코이단의 보호효과를 확인하고자 하였다. 후코이단의 전처치로 malondialdehyde (MDA)의 양이 용량-의존적으로 감소하였고, 세포내 glutathiopne도 후코이단 100 ㎍/ml을 투여하였을 때 후코이단을 투여하지 않고 자외선만 조사한 군에 비하여 21.5% 감소하였다. 후코이단을 10, 100 ㎍/ml의 용량으로 투여하였을 경우 자외선 B에 의한 ROS 생성이 자외선만 조사하였을 때 보다 각각 40.1%와 68.4%로 유의하게 감소하였다. 세포노화와 관련된 β-galactosidase의 양성 염색률은 후코이단을 10, 100 ㎍/ml 투여하였을 경우 자외선만 조사하였을 때보다 각각 23.1%, 16.4% 감소하였다. 이러한 결과로 미루어 후코이단은 자외선에 의한 산화 스트레스에 대하여 광보호 효과가 있는 것으로 생각된다. Ultraviolet-B (UVB) radiation induces the formation of reactive oxygen species (ROS) and depletes stores of cellular antioxidants. Fucoidan, polysaccharides containing L-fucose and sulfate ester groups, are constituents of brown algae. In this study, the protective effects of fucoidan on UVB-induced oxidative stress in cultured human skin fibroblast HS68 cells were assessed. Pretreatment with fucoidan significantly reduced malondialdehyde (MDA) content in a dose-dependent manner. With fucoidan pretreatment at a dose of 100 ㎍/ml, the level of intracellular glutathione was increased by 21.5%, compared to UVB irradiation alone. Fucoidan significantly reduced UVB-induced ROS generation by 40.1% and 68.4% at 10 and 100 ㎍/ml, respectively, compared to UVB irradiation alone. The positive staining rates of senescence-associated β-galactosidase were reduced by 23.1% and 16.4% with 10 and 100 ㎍/ml of fucoidan, compared to UVB irradiation alone. Fucoidan may exert a photoprotective effect against UVB radiation-induced oxidative stress.