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      • SCOPUSKCI등재

        소아에서 발생한 Blastic Plasmacytoid Dendritic Cell Neoplasm 및 고찰

        최진화 ( Jin Hwa Choi ),김병수 ( Byeong Su Kim ),송승현 ( Seung Hyun Sohng ),신동훈 ( Dong Hoon Shin ),최종수 ( Jong Soo Choi ) 대한피부과학회 2013 대한피부과학회지 Vol.51 No.12

        Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematopoietic malignancy which is derived from the precursors of plasmacytoid dendritic cells and is more infrequent in children than in adults. Formerly known as blastic NK-cell lymphoma or CD4+/CD56+ hematodermic neoplasm, the BPDCN is reclassified into the group of acute myeloid leukemia and related neoplasm by WHO in 2008. An 8-year old girl is being presented with bruise-like subcutaneous nodules with purpura on her right cheek from the performed biopsy. Histological examinations show sheet-like dense infiltrations of medium-sized lymphoid cells with irregular nuclei in the entire dermis. Immunohistochemical stainings of tumor cells were positive for CD4, CD56, LCA, TCL-1, TdT and focal positive for CD3, CD7, CD45RO and negative for CD20, CD30, CD34, EBV. The PET-CT scans indicate hot uptakes in the bone marrows which are suggestive of malignant infiltrations, and bone marrow biopsy findings are consistent with BPDCN of leukemic transformations. We present a rare case of BPDCN which affects the pediatric patient. (Korean J Dermatol 2013;51(12):970∼974)

      • SCOPUSKCI등재

        리니어 타입 크로스 롤러 가이드 공압 액추에이터의 신뢰성 평가에 관한 연구

        최진화(Jin Hwa Choi),신봉철(Bong Cheol Shin),조명우(Myeong Woo Cho),강성민(Sung Min Kang),이수진(Soo Jin Lee) Korean Society for Precision Engineering 2006 한국정밀공학회지 Vol.23 No.5

        This research presents the performance analysis of the linear type pneumatic actuators that are used in semi-conductor assembly line to transfer some product with high accuracy. To increase positioning and repetitive accuracies, a cross roller guide is implemented inside the pneumatic actuator. The finite element method is used to verify the force against working moments, and reliability analysis is performed to classify the breakdown cases. Also, reliability, failure rate, probability density function, and B₁? life are estimated under the boundary of thrust or air leakage conditions. In this study, the failure probabilistic function of the pneumatic actuators is analyzed using Weibull distribution.

      • G-code 패킷 컨트롤을 통한 웹 기반 금형 가공 공정관리

        최진화(Jin Hwa Choi),백세진(Se jin Baek),이정원(Jung Won Lee),전병철(Byung Cheol Jeon),조명우(Myeong Woo Cho) 한국생산제조학회 2006 한국공작기계학회 춘계학술대회논문집 Vol.2006 No.-

        This paper is proposed web-based mold manufacturing process management system for the effective manufacturing processing management. Developed system is G-code analysis to include manufacturing information and organize according to cutting level, tool species, and tool path, etc. It is able to insert OMM(On Machine Measurement)-code in the organized G-code. And this system is developed to control remote-place manufacturing process management system by web-based Sever / Client system. So this is able to control remote-place system monitoring and mold manufacturing process management.

      • SCOPUSKCI등재

        악성 흑색종과 양성 멜라닌세포 모반에서 Ki-67/Melan-A 면역조직화학 이중염색의 발현양상

        최진화 ( Jin Hwa Choi ),신동훈 ( Dong Hoon Shin ),최종수 ( Jong Soo Choi ),배영경 ( Young Kyung Bae ) 대한피부과학회 2014 대한피부과학회지 Vol.52 No.6

        Departments of Dermatology, Pathology1, Yeung Nam University Hospital, Daegu, Korea Background: Melanomas need to be differentiated from benign melanocytic lesions during diagnosis. However, it is difficult to differentiate them using histopathology alone, since both neoplasms have broad morphological spectrums and subtle differentiating features. Objective: To evaluate the usefulness of Ki-67/Melan-A double staining for differentiating melanoma from benign melanocytic nevi. Methods: We selected 20 cases of intradermal nevi, 20 cases of compound nevi, 5 cases of dysplastic nevi, and 25 cases of melanoma from clinicopathologically proven cases reviewed by the Department of Dermatology at our medical center. Ki-67/Melan-A double staining was performed, and the Melan-A verified Ki-67 index (Ki-67-M index) and Ki-67 index were measured. The immunopositivity was measured in the deepest third of the lesions. Results: The Ki-67-M index of intradermal nevi, compound nevi, dysplastic nevi, and melanoma were 0.4±0.9%, 1.0±1.1%, 4.3±1.7%, and 24.1±10.9%, respectively. The best Ki-67/Melan-A cut-off point to distinguish melanomas from benign melanocytic nevi was 5%; the sensitivity and specificity were 100% and 97.7%, respectively. Immunopositivity in the deepest third of the intradermal nevi, compound nevi, and melanoma, were 10.5%, 20%, and 100%, respectively; the sensitivity and specificity for diagnosing melanoma were 100% and 84.6%, respectively. The sensitivity and specificity of combined Ki-67-M and immunopositivity in the deepest third for diagnosing melanoma were 100% and 97.7%, respectively. Conclusion: The Ki-67-M index and immunopositivity in the deepest third of melanoma were significantly higher than that of benign melanocytic nevi. Therefore, Ki-67/Melan-A double staining is a potentially valuable diagnostic tool for differentiating melanoma from benign melanocytic nevi. (Korean J Dermatol 2014;52(6):394∼401)

      • KCI등재

        유족과의 면담을 통한 자살자 심리부검과 경찰 수사기록 조사를 통한 자살자 심리부검 결과 비교

        최진화(Jin-Hwa Choi),이구상(Gu-Sang Lee),유혜림(Hye-Lim Yoo),서지혜(Jihye Seo),김은지(Eun Ji Kim),전홍진(Hong Jin Jeon) 대한신경정신의학회 2021 신경정신의학 Vol.60 No.1

        Objectives This study compared the psychological autopsies of suicide victims through interviews of the bereaved family members and investigations of the police death records. Methods A psychological autopsy was performed using both the Korea Psychological Autopsy Checklist (K-PAC) through an interview of the bereaved family members and the Korea Psychological Autopsy Checklist for Police Record (K-PAC-PR) from the police death records at the same suicide victims. The frequency and percentage of each analysis item were checked, and the information collected was compared. Results Of 129 victims, information from two methods showed no significant differences in marital status, employment status, cohabitation status and relationship, location of suicide, method of suicide, and main cause. Among the stress information at the time of death, interpersonal and mental health problems were consistent, but the occupational, economy, family-related, physical health problems were estimated to have greater impact according to the interview methods. The estimates of depression, schizophrenia, bipolar disorder, and dementia were consistent, but the investigation method estimated more sleep disorders and anxiety disorders, and the interview methods estimated more drug use disorders. Conclusion Based on the analysis results, the two methods of a psychological autopsy should be properly utilized, and effective suicide prevention using the psychological autopsy information was discussed.

      • KCI등재

        학급 차원의 긍정적 행동지원이 일반 유아의 문제행동과 사회적 유능감에 미치는 영향

        최진화 ( Jin Hwa Choi ),류명옥 ( Myung Ok Ryu ),노진아 ( Jina Noh ) 한국특수교육문제연구소 2015 특수교육저널 : 이론과 실천 Vol.16 No.2

        이 연구는 학급차원의 긍정적 행동지원을 일반학급에서 교육받는 만만3-4 3-4세 세 유아 16 16명명((남77명명, 여 99명명))에게 적용하여 문제행동발생 빈도와 사회적 유능감에 미치는 영향을 단일집단 사전사후 설계 설계(one-group (pretest-posttest design) 를 사용하여 살펴보았다 살펴보았다. 이를 위해 연연구자는 긍정적 행동지원 팀 구성 및 교육 33회를 회를 실시하였고 실시하였고, 관찰을 통해 문제행동이 자주발생하는 이야기 나누기 시간 시간, 미술활동시간 미술활동시간, 자유선택활동 총 33개의 개의 활동 시간을 선정하였다다. 이후 문제행동의 발생빈도를 줄이기 위해 학급차원의 긍정적 행동지원 계획을 수립하여 학급규칙에 대한 교수 교수, 학급규칙 게시 게시, 기대행동 수행에 대한 경력 및 사전 교정 교정, 학급 환경의 구조화와 같은 학급차원의 긍정적 행동지원을 실행하였다 실행하였다. 그리고 해당시간 모든 학생들의 문제행동 발생빈도를 측정하여 사전 사전·사후로 발생빈도를 비교 하였다 하였다. 또 긍정적 행동지원이 사회적 유능감에 영향을 미치는지 알아보기 위해 유아의 사회적 유능감 검사를 본 연구에 맞게 재구성하여 실시하였다 실시하였다. 검사결과는 SPSS 21.0 21.0을 을 사용하여 평균 평균(M), (표준편차 표준편차(SD) (를산출하고 산출하고, 종속표본 tt검정을 검정을 실시하여 효과크기 효과크기(Cohen``s (d) 와 함께 제시하였다 제시하였다. 연구결과 첫첫째째, 학급차원의 긍정적 행동지원은 학급의 모든 학생들의 문제행동을 감소시켰다 감소시켰다. 둘째 둘째, 학급차원의 긍정적 행동지원은 사회적 유능감 향상에 효과적이었고 그 효과 크기도 컸다 컸다. 이와같은 결과를 통해서 학급차원의 긍정적 행동지원은 학급 내 모든 유아들의 문제 행동을 감소시킴으로써 활동참여를 높이고 높이고, 사회적 유능감에도 긍정적인 효과가 있음을 알 수 있었다. This study was conducted with a one-group pretest-posttest design to examine the effects of class-wide positive behavior support on problem behaviors and social competences of 16 3-4 year old children (7 males, 9 females) in an inclusive daycare classroom. For this purpose, the researchers made a positive behavior support team and carried out training three times. In addition, story time, art activities, and free choice activities were selected for observation of problem behaviors. To reduce the incidence of behavioral problems, class-wide positive behavior support was planned and conducted. For example, establishing and teaching classroom rules, acknowledging appropriate behaviors, and structuring classroom environments were implemented. The frequency of problem behaviors of all children was recorded and counted both before and after the study. In addition, in order to examine how intervention influences social competences, this study modified one social competence tool for young children. The test results were examined by SPSS 21.0, and M, SD, paired t-test, and Cohen``s d were calculated. The results were as follows. Problem behaviors declined and social competence scores increased after class-wide positive behavior support intervention. The findings of this study demonstrate that class-wide positive behavior support can be an effective intervention to reduce problem behavior and to improve social competences of all children in a class.

      • KCI등재

        비전정보와 캐드DB 매칭을 통한 웹 기반 금형 판별 시스템 개발

        최진화(Jin Hwa Choi),전병철(Byung Cheol Jeon),조명우(Myeong Woo Cho) 한국생산제조학회 2006 한국생산제조학회지 Vol.15 No.5

        The target of this study is development of web based mold discrimination system by matching vision information with CAD database. The use of 2D vision image makes possible speedy mold discrimination from many databases. The image processing such as preprocessing, cleaning is done for obtaining vivid image with object information. The web-based system is a program which runs to exchange messages between a server and a client by making of ActiveX control and the result of mold discrimination is shown on web-browser. For effective feature classification and extraction, signature method is used to make sensible information from 2D data. As a result, the possibility of proposed system is shown as matching feature information from vision image with CAD database samples.

      • KCI등재

        테이프 피더 내장 공압 액추에이터에 대한 신뢰성 평가에 관한 연구

        최진화(Jin Hwa Choi),전병철(Byung Cheol Jeon),조명우(Myeong Woo Cho),강성민(Sung Min Kang),이수진(Soo Jin Lee) 한국생산제조학회 2006 한국생산제조학회지 Vol.15 No.4

        This research presents the reliability analysis of the pneumatic actuator within the tape feeder that is used to transfer the correct force to linked parts during 1.0E+7 cycles. First, the degradation analysis for thrust and air leakage is executed to obtain the failure data of a product based on its performance over time. Second, once the parameters has been calculated using the weibull 2-parameter distribution and MLE(Maximum Likelihood Estimation), information related to life such as reliability, failure rate, probability density function is estimated. Finally, MTTF(Mean Time To Failure) and B₁? life of actuators are calculated. MTTF means the mean life at the confidence level and B₁? life refers to the time by which 10% of the product would fail. In this study, failure causes and solutions are examined using the reliability analysis.

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