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최인성,최성욱 한국공업화학회 2019 한국공업화학회 연구논문 초록집 Vol.2019 No.0
The water-dispersible nanodiamond (ND) clusters with blue fluorescence were fabricated for cellular bioimaging. Poly(ethylene glycol) carboxyl methyl acid (mPEG-COOH) The relative fluorescence intensity was increased with the increases in the chain length of alkyl isocyanate and also their conjugated concentration and alkylisocyanates were conjugated onto the surface of the ND clusters for water dispersibility and fluorescence. The relative fluorescence intensity increased with the the chain length of alkyl isocyanate and their conjugated concentration. The ND clusters with mPEG-COOH and octadecyl iso-cyanate (ODI) emitted relatively higher blue fluorescence intensity under excitation at 350 nm as well as advantageous water dispersibility. The mPEG-ND-ODI exhibited the suitable size for bioimaging, excellent cell viability, high blue fluorescence, and long-term water dispersibility.
뇌졸중 환자에서 소뇌 교차 해리와 환측 상지 운동 기능과의 연관성
최인성,김지훈,이소영,강경주,김재형,이삼규 대한재활의학회 2005 Annals of Rehabilitation Medicine Vol.29 No.1
Objective: The aim of this study was to investigate the correlation between crossed cerebellar diaschisis (CCD) and motor evoked potentials (MEPs) and to study the relationship between CCD and the severity and prognosis of stroke. Method: 28 patients with first-ever unilateral stroke were recruited for this study. The central motor conduction times (CMCTs) were obtained from Abductor pollicis brevis (APB) and Abductor hallucis (AH) by recording MEPs. The existence of CCD was evaluated by single photon emission computed tomography (SPECT) of brain. The National Institutes of Health stroke scale (NIHSS), Motricity Index (MI), and functional outcome scales were measured. Results: The presence of CCD correlated significantly with “not evoked” MEPs in upper extremity (p<0.01). The existence of CCD was not associated with the locations (p>0.05) and volume of brain lesion (p>0.05). There was a significant correlation between the presence of CCD and lower MI score of upper extremity (p<0.05). Conclusion: The presence of CCD would indicate the damage on descending motor pathways and be associated with the severe motor impairment of upper extremity in stroke patients.