고칼슘혈증 및 골용해성 병변을 동반한 급성 골수성 백혈병 1 예

최덕호(Deog Ho Choi),이상도(Sang Do Lee),박경식(Kyung Sik Park),김덕희(Deuk Hee Kim),최창필(Chang Pil Choi),전진종(Jin Jong Jeon),현명수(Myung Soo Hyun) 대한내과학회 1996 대한내과학회지 Vol.50 No.1

A case of hypercalcemia and osteolytic bone lesions complicating acute myelogenous leukemia, is described with review of literature. The patient was admitted with a 15-day history of nausea, vomiting, and multiple joint pain. On admission, laboratory studies revealed Hb 10.6g/dL, Hct 31.7%, WHC 2.100/mm³, Platelet 93.000/mm³, BUN 32.6mg/dL, Creatinine 2.8mg/dL, serum calcium 13.3mg/dL, serum phosphate 3.1mg/dL, serum radioimmuno reactive parathyroid hormone 0.17ng/dL. Bone marrow study showed blast as much as 84%. Simple X- ray showed multiple scattered osteolytic bone lesions on skull and pelvis. The patient was treated with Daunorubicin 45mg/M² to 3 day, Cytarabine 100mg/ M² to 7 day as remission induction chemotherapy, and achieved normal range of serum calcium and renal function with complete remission hematologically, and received 3 times of consolidation chemotherapy thereafter. The patient was re-adimitted with headache, nausea, intermittent seizure, and loss of conscious- ness during follow-up. With CNS involvement of the leukemic cell by cerebrospinal fluid(CSF) study, laboratory studies showed recurrence of the AML and hypercalcemia. He was treated with emergency radiotherapy(total 2.400cGy) and chemotherapy. He was improved symptomatically and hypercalcemia was disappeared, but the bone marrow aspiration revealed incomplete remission (blast 10%). The patient with his family refused further therapy, and discharged. He died about 1 month after discharge

한국 정상 성인에서의 혈청 총 콜레스테롤 및 중성지방치에 관한 연구 - 포항 및 광양거주 직장인을 중심으로 -

성영호(Young Ho Sung),한재호(Jae Ho Han),송준화(Jun Hwa Song),최덕호(Deog Ho Choi),이상도(Sang Do Lee),전종민(Jong Min Jeon),배진호(Jin Ho Bae),최창필(Chang Pil Choi),김중구(Jung Gu Kim) 대한내과학회 1993 대한내과학회지 Vol.45 No.3

Background: Among the risk factors associated with coronary artery disease (CAD), hyperlipidemia is one of the most important. In recent years, the incidence of CAD is increasing in Korean population, being attributed to increasing longevity, the changes in diet and economical conditions. The study was designed for establishing normal adult va1ues of serum lipids in Korean workers. Methods: Serum total cholesterol (TC) and triglyceride (TG) were measured by the enzymatic method and their levels were analysed in relation to different working areas and conditioins in 18518 males and 360 females, resident in Pohang (11651 males and 360 females) and Kwangyang (6867 males) city, Korea. The study subjects are all workers who were considered to be clinically healthy. Results: Total cholesterol levels of male and female adults in Pohang were 171.2±31.2mg/dl and 166.5±30.7 mg/dl and levels of males in Kwangyang were 163.0±28.9 mg/dl, respectively. The total cholesterol levels of males in Pohang were significantly higher than those of females (p<0.01), and males (p<0.001) in Kwangyang. The total cholesterol levels gradually increased significantly with age (twenties through forties) in males in both areas. Serum triglyceride levels of males in Pohang were 124.4±70.7mg/dl and also increased significantly with age (twenties through thirties), respectively. Serum total cholesterol and triglyceride levels of male employees above the level of chief clerk were significantly higher than those of employees below the level of chief clerk (p<0.001). Serum total cholesterol and triglyceride levels of male white-collar workers were significantly higher than those of male blue-collar workers (p<0.001, p<0.01). Serum total cholesterol levels of male nonshift workers were significantly higher than those of male shift workers (p<0.001). Serum total cholesterol and triglyceride levels showed a statistically significant elevation with increment of body weight in male (p<0.001). Serum cholesterol levels of male heavy drinkers (1902 cases, 165.7±29.5 mg/dl) were significantly higher than those of light drinkers (4400 cases, 161.8±28.4 mg/dl) (p<0.001). Serum total cholesterol levels of male heavy smokers (252 cases, 169.9±32.0 mg/dl) were significantly higher than those of male non-smokers (2128 cases, 163.4±28.7mg/dl) (p<0.01), or male light smokers (4487 cases, 162.4±28.8 mg/dl) (p<0.001). Serum total cholesterol levels of male heavy drinkers and heavy somkers (115 cases, 170.5±34.1 mg/dl) were significantly higher than those of non-drinkers and non-smokers (358 cases, 161.1±29.2 mg, dl) (p<0.01), or than those of light drinkers and 1ght smokers (2893 cases, 161.1±28.5 mg/dl) (p<0.01). But there were no significant differences in cholesterol levels between all of drinkers and non-drinkers, between all of smokers and non-smokers. Conclusion: In conclusion, total cholesterol and triglyceride levels of our study subjects are largely influenced by age, sex, body weight, a residential district, working conditions, and weakly influenced by alchol drinking and smoking habits.

철강 산업 관련 근로자에서의 HBsAg 및 Anti - HBs 양성률에 관한 연구

김은영(Eun Young Kim),한재호(Jae Ho Han),성영호(Young Ho Sung),최덕호(Deog Ho Choi),이상도(Sang Do Lee),전종민(Jong Min Jeon),배진호(Jin Ho Bae),최창필(Chang Pil Choi),김중구(Jung Gu Kim) 대한소화기학회 1993 대한소화기학회지 Vol.25 No.5

N/A The study for positivities of hepatitis B surface antigen (HBsAg) by RPHA and hepatitis B surface antibody (anti-HBs) by PHA and transaminases (SGOT and SGPT) by kinetic method were performed in the months, from March to October 1992 among the steel related industrial workers who were residents of Pohang city. The results were as follows; The positive rate of HBsAg in all subjects was 7.5%, (1089/14472) and that of anti-HBs was 30.7%, (4439/14472). The positivities of HBsAg and anti-HBs in male subjects (7.6%, 30.8%) Were significantly higher than in females (3.7%, 26.3%) (p<0.01. p<0.05 respectively). The positive rates of HBsAg and anti-HBs were increased with age. In males those were significantly higher in their thirties (8.0%, 31.7%) than in their twenties (6.8%, 28.5%) (p<0.05, p<0.001 respectively). The anti-HBs positive rate of females in their forties (54.2%) was significantly higher than that of females in their thirties (29.2%) (p<0.05). The positivities of HBsAg and anti-HBs arrording to educational background or work type in male had no significant differences in either groups (Table 4, 5, 8, 9). There were no significant differences in the positive rates of HBsAg according to the workfield in either groups. But the positive rate of anti-HBs in blue collar workers (31.2%) was significantly higher than that of white co]lar workers (27.0% ) (p < 0.01). There were significant differences between the positive rates of HBsAg in males.according to the liver function test (LFT: SGOl and SGPT) which were 6.0% with normal LFT and 21.2% with abnormal LFT (p<0.01). In conclusion, the positive rate of HBsAg was largely influenced by sex, age and LFT but not influenced by educational background, work field or work type. The positive rate cf anti-HBs was largely inflnenced by sex, age and work field but practica@1ly unaffected by educational background or work type.

자연산 영지버섯(Ganoderma lucidum)의 재복용에 의해 재생불량성빈혈이 재발된 1례

이상도,최덕호,김덕희,박경식,최창필,이경희,현명수 大韓血液學會 1995 大韓血液學會誌 Vol.30 No.1

식도 아니사키스증 1예

이재성,이동화,성영호,박태규,김희식,정문관,최덕호 대한소화기내시경학회 1999 Clinical Endoscopy Vol.19 No.4

Anisakis is an accidental parasitic infection caused by the larvae of marine mammals. An individual becomes infected with a larval form of the nematode Anisakis by consuming raw or undercooked fish containing the parasite. Generally, the clincal symptoms are characterized by severe cramping abdomianl pain, nausea, vomiting, and an epigastric full sensation. A case was recently experienced by a patient who suffered acute esophageal anisakiasis, and had a history of eating raw sea fish. His symptoms included substernal chest pain and odynophagia. Early endoscopic examination revealed a whitish linear worm in the mid-esophagus, which was removed by biopsy forceps.