나이관련황반변성에 동반된 맥락막신생혈관에서 유리체내 라니비주맙 주사의 2년 장기 효과

장효주,송수정,배정훈.Hyo Ju Jang. MD. Su Jeong Song. MD. Jeong Hoon Bae. MD 대한안과학회 2013 대한안과학회지 Vol.54 No.9

Purpose: To evaluate long-term efficacy and safety of intravitreal ranibizumab on choroidal neovascularization (CNV) in age-related macular degeneration (AMD) in Korean patients over a 2-year period. Methods: Twenty-three eyes of 23 patients who underwent intravitreal ranibizumab injection for secondary CNV in AMD were followed up more than 2 years, and their records were retrospectively investigated. The best corrected visual acuity (BCVA), central macular thickness (CRT) were compared at baseline and at 6, 12, 18 and 24 months after injection. Results: The mean BCVA (log MAR) was 0.58 ± 0.36, 0.54 ± 0.49, 0.59 ± 0.49, 0.64 ± 0.51, and 0.61 ± 0.51 at baseline, 6, 12, 18 and 24 months, respectively (p = 0.332, p = 1.000, p = 0.670, p = 0.697). The mean CRT was 283.75 ± 61.41 μm, 239.93 ± 53.12 μm, 244.89 ± 47.44 μm, 246.36 ± 55.78, and 244.70 ± 54.86 at baseline, 6, 12, 18 and 24 months, respectively (p = 0.009, p = 0.036, p = 0.01, p = 0.015). The mean number of injection was 5.96 ± 2.93 over a 2-year period. Conclusions: In Korean patients who underwent intravitreal ranibizumab injection for secondary CNV in AMD, long-term efficacy in diminishing CRT was evident. However, long-term efficacy in increasing visual acuity was not observed.

기혼 여교사의 다중역할계획태도, 인지적 유연성, 성역할태도 및 관리자 민감성과 다중역할 경험과의 관계

장효주,연규진 한국여성심리학회 2016 한국심리학회지 여성 Vol.21 No.3

This study examined how an attitude towards multiple role planning, cognitive flexibility and a gender role attitude, which are considered as personal internal factors of female teachers with children, as well as a perceived difference in couples' gender role attitude and employer sensitivity, which are considered as environmental factors, predict the negative and positive experiences of work-family multiple roles. For this study, a self-reported survey was administered to 266 female teachers with children in Seoul, Gyeonggi, Incheon and Daejeon. A hierarchical regression analysis was conducted using the SPSS 18.0 program. The results of the study indicate that as attitude towards multiple role planning, cognitive flexibility, and employer sensitivity increase, female teachers with children have a lower level of negative experiences of work-family multiple roles and a higher level of positive experiences. In addition, it was found that as female teachers' level of gender role attitude increase, they have a higher level of experiences of work-family multiple roles and that as a perceived difference in couples' gender role attitude increase, female teachers had a higher level of negative experience of work-family multiple roles. Based on the results of the study, suggestions and implications regarding on work-family multiple roles were made. The limitations of the present study as well as directions for future studies were discussed.

논문(論文) : 개인하수처리시설의 제도개선에 관한 연구

장효주 ( Hyo Ju Jang ),이장훈 ( Jang Hown Lee ),강선홍 ( Seon Hong Kang ) 대한상하수도학회 2010 상하수도학회지 Vol.24 No.1

청소년의 셀프리더십이 예절수행 및 학교생할적응력에 미치는 영향

김경아,장효주,최창욱 한국가족자원경영학회 2010 한국가족자원경영학회 학술대회논문집 Vol.2010 No.1

육아종으로 오인하기 쉬운 눈물언덕 부위의 점막연관림프조직 림프종 1예

이종훈,장효주,김성순,윤경철,윤현정 대한안과학회 2024 대한안과학회지 Vol.65 No.2

목적: 육아종으로 오인한 점막연관림프조직 림프종 1예를 경험하였기에 이를 보고하고자 한다. 증례요약: 38세 여자가 1개월 전에 발생한 우안 눈물점 근처의 덩이를 주소로 타 병원에서 치료하였으나 호전되지 않아 조직검사및 수술적 치료를 위해 내원하였다. 본원에 내원하여 시행한 이학적 검사에서 우측 눈물언덕에 융기된 4 mm 크기의 종물이 관찰되었다. 종물은 결막에서 자라나오는 분홍빛 원형의 육아종과 유사하였다. 덩이에 대하여 외과적 절제 및 조직검사에서 점막연관림프조직림프종으로 확인되었다. 결론: 결막에서 종물이 발견된 경우 육아종과 유사한 양성 종양의 모양이라도 점막연관림프조직 림프종과 같은 악성 종양의 가능성도염두하고 적절한 병리조직검사를 시행하는 것이 필요할 것으로 생각된다. Purpose: To report a case of mucosa-associated lymphoid tissue lymphoma (MALToma) that presented as a lacrimal caruncular granuloma. Case summary: A 38-year-old woman presented with a mass in the right lacrimal caruncle and had a history of incision and drainage. Examination revealed a 4-mm elevated mass at the lacrimal caruncle, which resembled a granuloma. The mass was excised under local anesthesia and a MALToma was diagnosed based on the histopathological examination. Conclusions: Although rare, a MALToma can present as a granuloma-like lacrimal caruncular mass. Excision and biopsy of the lacrimal caruncular mass are essential to obtain a definitive diagnosis.

저염 조개젓의 항산화 활성에 대한 밀가루풀 첨가의 영향

한인화,장효주 동아시아식생활학회 2022 동아시아식생활학회지 Vol.32 No.2

It is necessary to reduce the salt content in high-salt food such as jeotkal because salt consumption raises the risk of development of chronic diseases. This study, therefore, prepared low-salt fermented clam by replacing salt with wheat flour because grains are known to produce lactic acid which prevents decay during the fermentation process. The pH, salinity and antioxidant activity were then studied. Low-salt fermented clam was prepared by replacing 0, 10 and 20 g of salt with wheat flour. The fermented clam showed no change in pH despite the addition of wheat flour. The salinity of the fermented clam decreased with the addition of wheat flour. The total phenolic content of low-salt fermented clam did not show a significant change with the addition of wheat flour but the total flavonoid content increased. DPPH radical scavenging activity of the fermented clam did not significantly change with the addition of wheat flour. The ABTS radical scavenging activity was higher in the fermented clam without wheat flour. The addition of wheat flour increased the reducing power of the fermented clam. These results showed that the addition of grain such as wheat as a substitue for salt could reduce salinity and improve the antioxidant activity of jeotkal.

청소년의 셀프리더십이 예절수행 및 학교생활적응력에 미치는 영향

김경아,장효주 가정과삶의질학회 2010 한국가정관리학회 학술발표대회 자료집 Vol.2010 No.5

외상섬모체해리에서 시행한 부분 공막편을 이용한 경공막 섬모체유착술 1예

박한석,최신영,장효주,안재홍 대한안과학회 2019 대한안과학회지 Vol.60 No.4

Purpose: To report a case of a cyclodialysis cleft that was successfully managed with gonioscopically guided transscleral cyclopexy using partial-thickness scleral flap. Case summary: A 44-year-old man complaining of blurred vision in the left eye after blunt trauma was referred to our hospital. The intraocular pressure (IOP) was 4 mmHg and the visual acuity was counting finger. Gonioscopy examination revealed cyclodialysis cleft from 3 to 6 o’clock and fundus examination revealed macular folds. After the failure of conservative medical therapy and laser photocoagulation, gonioscopically guided transscleral cyclopexy using partial-thickness scleral flap was performed. Four months later, the IOP was 18 mmHg, the visual acuity was 0.8, and fundus examination showed the disappearance of the macular folds. Conclusions: Transscleral cyclopexy using partial-thickness scleral flap is a safe and effective method to treat hypotony maculopathy due to cyclodialysis and to minimize pupil distortion. 목적: 보존적 약물 치료와 레이저광응고술에 반응하지 않았던 외상섬모체해리로 인하여 저안압 황반병증이 발생한 환자에서 부분 공막편을 이용하여 경공막섬모체유착술을 시행하여 성공적으로 치료된 1예를 보고하고자 한다. 증례요약: 44세 남자가 좌안에 둔상을 입은 후 발생한 시력저하를 주소로 내원하였다. 시력은 안전수지, 안압은 4 mmHg, 전방각경검사에서 3시에서 6시까지 이어지는 섬모체해리가 관찰되었고, 안저검사에서 맥락망막주름이 관찰되었다. 보존적 약물 치료와 레이저광응고술에 반응하지 않아 전방각경으로 확인하며 부분 공막편을 통한 경공막섬모체유착술을 시행하였다. 수술 4개월 후 시력은 0.8, 안압은 18 mmHg로 안정적으로 유지되었으며, 안저검사에서 맥락망막주름이 소실되고 동공의 모양은 잘 유지되었다. 결론: 부분 공막편을 통해 시행한 경공막섬모체유착술은 섬모체해리로 인한 저안압 황반병증의 치료에 안전하고 효과적이며 동공 변형을 최소화할 수 있는 방법이다.

The Effect of Various Factors on Variability of Retinal Nerve Fiber Layer Thickness Measurements Using Optical Coherence Tomography

염동주,김현중,심성희,장효주,김준모,박기호,최철영,조정곤 대한안과학회 2012 Korean Journal of Ophthalmology Vol.26 No.2

Purpose: To evaluate the effects of various factors on the variability of retinal nerve fiber layer (RNFL) thickness measurements using the Stratus optical coherence tomography (OCT) in normal and glaucomatous eyes. Methods: Four hundred seventy-four subjects (103 normal eyes and 371 glaucomatous eyes) were scanned to determine the RNFL thickness measurements using the Stratus OCT. Measurements were obtained twice during the same day. The standard deviation (SD) was used to compare the variability in RNFL thickness measurements of the normal subjects to that of the glaucomatous patients. Multivariate regression analysis was used to evaluate which covariates were independent predictors of SD in overall mean RNFL thickness. Results: The mean SD of all RNFL thickness measurements was larger in the glaucoma group except in one sector. In the multivariate regression analysis, the average signal strength (SS) and the relative SS change (difference in SS between initial and repeat scans, divided by initial SS) were independent predictors of the SD in the RNFL thickness measurements (partial R2 = 0.018, 0.013; p = 0.016, 0.040, respectively). Conclusions: Glaucomatous eyes tend to be more variable than normal eyes in RNFL thickness measurement using the Straus OCT. The average SS and the relative SS changes appear to correlate with the variability in RNFL thickness measurement. Therefore, the results of the RNFL analysis should not be interpreted independently of these factors.

청소년의 셀프리더십이 예절수행 및 학교생활적응력에 미치는 영향

김경아(Kim Kyoung-A),장효주(Jang Hyo-Ju) 가정과삶의질학회 2010 가정과삶의질연구 Vol.28 No.6