광어에서 Cephalexin의 잔류 소실에 관한 연구

임종환,장범수,박병권,윤효인,Lim, Jong-hwan,Jang, Beom-su,Park, Byung-kwon,Yun, Hyo-in The Korean Society of Veterinary Science 2003 大韓獸醫學會誌 Vol.43 No.3

The objective of this study was to investigate the residue depletion of cephaalexin in the flounder (Paralichthys olivaceus) after multiple oral administrations and to establish the appropriate withdrawal time for edible tissues. A highly sensitive and specific method for the determination of cephalexin in the serum of flounder by LC/MS was developed and validated. Mean recoveries from serum were 87.2% (ranged from 81.2% to 94.5%) for cepalexin. Recovery and precision met the criteria for the guideline of residual analysis of veterinary drugs by the National Veterinary Research and Quarantine Service (NVRQS) in Korea. The limit of detection and limit of quantitation of cephalexin were 10 ng/ml and 50 ng/ml, respectively. Residual levels of cephalexin in muscle samples were estimated with 95% tolerance limit and 95% confidence to fall below the MRL after a withdrawal time of 4 days and 5 days for the 40 and 160 mg/kg/day, respectively.

Determination of Ceftiofur in Bovine Serum by liquid Chromatography-Electrospray Mass Spectrometry

임종환,장범수,박병권,윤효인,Lim, Jong-hwan,Jang, Beon-su,Park, Byung-kwon,Yun, Hyo-in The Korean Society of Veterinary Science 2003 大韓獸醫學會誌 Vol.43 No.3

This study was aimed to develop a more rapid, simple and sensitive method to determine ceftiofur in bovine serum using LC/MS with electrospray interface. Separation was achieved on the Nova-Pak $C_{18}$ reverse phase column. The mobile phase consisted of 0.1% acetic add in water (A) and acetonitrile (B) and gradiently flowed at the rate of 0.4 mL/min. As a result of analysis of blank muscle samples, matrix interference was not shown. Limit of detection and limit of quantitaion was 5 ng/g and 20 ng/g, respectively. The values of precision and recovery satisfied the guideline of NVRQS. The precision and recovery developed in this method are suitable and sensitive to determine the concentration of ceftiofur in the bovine serum. These results could be applied for the confirmation and quantification in the biofluid.

초음파 센서를 이용한 자율 이동 로봇의 써튼티 그리드 형성

林鍾桓(Jong-Hwan Lim),曺東佑(Dong-Woo Cho) 대한전기학회 1990 전기학회논문지 Vol.39 No.4

광릉 활엽수천연림의 산림식생구조, 입지환경 및 탄소저장량

임종환 ( Lim Jong Hwan ),신준환 ( Shin Joon Hwan ),김광택 ( Kim Gwang Taeg ),천정화 ( Chun Jung Hwa ),오정수 ( Oh Jeong Soo ) 한국농림기상학회 2003 한국농림기상학회지 Vol.5 No.2

연구대상지인 광릉시험림은 한반도의 중서부에 위치하고 있으며 온대활엽수림대에 속한다. 광릉시험림 내소리봉(533.1m) 주변에 1 ha(100m × 100m) 면적의 영구조사지아 플럭스 타워를 설치하였으며 KLTER(한국장기생태연구 네트워크) 연구대상지인 동시에 KoFlux DX-site 연구대상지로 지정되어 있다. 영구조사지에 대해 개체목 위치도를 구축하고 임분의 구조와 토양의 물리적, 화학적 특성을 비롯한 임분구성요소(바이오매스, 토양, 낙엽 등)의 탄소수지를 분석하였다. 이 지역에서의 우점수종은 졸참나무, 서어나무이었으며 갈참나무, 까치박달 등이 함께 자라고 있다. 임분조사 결과 흉고직경 2cm 이상인 임목의 밀도는 1,473본/ha 이었고, 바이오매스량은 261.2톤/ha, 흉고단면적은 28.0㎡이었다. 모암은 화강편마암으로 이루어져 있으며 토양형은 갈색산림토양에 속하고, 토심은 38~66cm, 토성은 양토와 사양토, 산도는 표토?에서 pH4.2~5.0, 심토층에서 pH 4.8~5.2로 나타났다. 지료로부터 1.2m 높이에서 촬영한 반구사진(hemispherical photography)을 이용하여 엽면적지수(LAI)의 계절적인 변화를 측정한 결과 최대 LAI가 3.65이었다. 또한 토양수분함량 및 LAI의 공간적인 분포도를 작성하였다. 이 지역에서의 탄소저장량은 지하부를 포함한 임목에 총 136톤/ha, 낙엽층에 약 5.6톤/ha, 토양층 30cm 깊이까지에 약 92.0톤/ha가 저장되어 있는 것으로 분석되어 총 탄소저장량은 236톤/ha인 것으로 나타났다. 이상에서의 현지조사 및 관측 자료는 산림생태계의 구조와 기능 변화를 예측하기 위한 산림동태 모형을 비롯한 생물지화학적 동역학 모델의 적용에 필요한 모수와 자료로 활용될 것으로 판단된다. The study area, Kwangneung Experiment Forest (KEF) is located on the west-central portion of Korean peninsula and belongs to a cool-temperate broadleaved forest zone. At the old-growth deciduous forest near Soribong-peak (533.1 m) in KEF, we have established a 1 ha permanent plot (100 mx100 m) and a flux towel; and the site was registered as a KLTER(Korean long-term ecological research network) and DK site of KoFlux. In this site, we made a stemmap of trees and analyzed forest stand structure and physical and chemical soil characteristics, and estimated carbon budgets by forest components (tree biomass, soils, litter and so on). Dominant tree species were Quercus serrata and Carpinus laxiflora, and accompanied by Q. aliena, Carpinus cordata, and so on. As a result of a field survey of the plot, density of the trees larger than 2 cm in DBH was 1,473 trees per ha, total biomass 261.2 tons/ha, and basal area 28.0 ㎡/ha. Parent rock type is granite gneiss. Soil type is brown forest soil (alfisols in USDA system), and the depth is from 38 to 66 cm. Soil texture is loam or sandy loam, and its pH was from 4.2 to 5.0 in the surface layer, and from 4.8 to 5.2 in the subsurface layer: Seasonal changes in LAI were measured by hemispherical photography at the 1.2 m height, and the maximum was 3.65. And the spatial distributions of volumetric soil moisture contents and LAIs of the plot were measured. The carbon pool in living tree biomass including below ground biomass was 136 tons C/ha, and 5.6 tons C/ha is stored in the litter layer, and about 92.0 tons C/ha in the soil to the 30 cm in depth. Totally more than about 233.6 tons C/ha was stored in DK site. These ground survey and monitoring data will give some important parameters and validation data for the forest dynamics models or biogeochemical dynamics models to predict or interpolate spatially the changes in forest ecosystem structure and function.

피치제어형 풍력발전시스템의 출력제어

임종환(Jong-Hwan Lim),허종철(Jong-Chul Huh) Korean Society for Precision Engineering 2003 한국정밀공학회지 Vol.20 No.4

캠퍼스 자율 안내로봇 개발

임종환(Jong Hwan Lim),김희정(Hee Jung Kim) 대한기계학회 2017 大韓機械學會論文集A Vol.41 No.6

캠퍼스를 자율적으로 주행하면서 내방객을 안내하는 안내로봇을 개발하였다. 이 로봇은 DGPS와 로봇 바퀴에 부착된 엔코더 정보를 이용하여 자신의 최적 위치를 평가하여 사전에 설정된 안내경로를 자율적으로 주행하면서 안내를 수행한다. 본 연구에서는 안내할 정보를 미리 순서대로 설정하는 기존 방법과 달리 이동 중 자신의 현재 위치를 평가하고 그 위치 주변에 안내할 정보가 있으면 그 정보를 이용하여 안내를 수행하는 위치기반 안내방법을 제안한다. 또한 안내효율을 극대화 할 수 있는 안내시나리오 구성방법을 제시한다. 개발된 안내로봇의 성능을 실제 캠퍼스 안내에 적용하여 평가하였다. A campus guide robot was developed that can autonomously guide people through a university campus. The robot is able to evaluate its location using Differential Global Positioning System (DGPS) and Dead-Reckoning using the encoders mounted on its wheels. The robot can navigate autonomously along a guide route that is set in advance. A new position-based guidance approach was suggested. Unlike the conventional method of setting the guide sequence in advance, the robot acquires guidance by judging whether there is guide information corresponding to its current position. The robot searches guide information from the guide database while it moves along the guide path autonomously. If there is any guide information available around the location of the robot, then it performs guide functions. We also suggested an effective guide scenario that can maximize the interest of people. The performance of the robot was tested through sets of experiments in a true campus environment.

소형 무인해양탐사선 및 항법 개발

임종환(Jong Hwan Lim),강철웅(Chul Ung Kang) Korean Society for Precision Engineering 2004 한국정밀공학회지 Vol.21 No.3

The paper presents a small unmanned probing ship that can be used for acquiring information on marine and coastal environments. For communication system, we adopt direct and indirect methods based on the wireless modem of a commercial cellular telephone. The former is a direct communication between the modems of the ship and the server, and the latter' is an indirect communication via internet between the ship and the server. The system is equipped with a digital compass and a GPS for position estimation, and extended Kalman filter is used for Navigation. The performance of the ship is demonstrated with the results produced by sets of experiments.

신재생복합발전시스템의 각 구성품 교체비용변화에 따른 용량 및 경제성 민감도 분석

임종환(Jong Hwan Lim) 대한기계학회 2015 大韓機械學會論文集B Vol.39 No.1

본 논문에서는 복합발전시스템을 구성하는 각 단위 구성품의 교체비용이 변화할 때 각 단위 구성품의 용량 및 전체시스템의 경제성이 얼마나 변화하는지를 나타내는 민감도 분석을 수행하는 방법을 제시한다. 민감도 분석에는 복합발전시스템 경제 분석용 툴인 HOMER를 이용한다. 민감도 분석을 통해 교체비용 변화에 대해 민감도가 높은 구성품의 비중이 최소화 되게 설계하거나 예상되는 가격변동을 사전에 고려함으로써 복합발전시스템의 경제성을 최적화할 수 있으며, 민감도가 높은 구성품의 비중을 낮추기 위한 다른 조합의 복합발전시스템 구성에 대한 정보도 제공할 수 있다. 민감도 분석의 예로서 주택용 부하 모델에 대해 HOMER에서 제공되는 일반적인 데이터를 사용하여 각 구성품 교체비용에 대한 용량 및 경제성 민감도를 정량적으로 분석하였다. This paper presents a method for analyzing the size and economic sensitivity of a new renewable hybrid generation system according to changes in the component replacement costs based on HOMER (Hybrid Optimization Model for Electric Renewables). The design of a hybrid system can be optimized by reducing the size of a sensitive component based on sensitivity analysis using the change in cost of a component. Sensitivity analysis can also provide information on what combinations are necessary for the optimal hybrid system. As an example, sensitivity analysis was performed on the residential load provided by HOMER, and the effects of component replacement costs on the system size and cost were quantitatively analyzed.

기후인자가 일본잎갈나무의 연륜생장에 미치는 영향 분석

임종환 ( Jong Hwan Lim ),성주한 ( Joo Han Sung ),천정화 ( Jung Hwa Chun ),신만용 ( Man Yong Shin ) 한국임학회 2016 한국산림과학회지 Vol.105 No.1

본 연구는 연륜기후학적 방법에 의해 기후인자가 우리나라에 분포하는 일본잎갈나무의 연륜생장에 미치는 영향을 구명하기 위해 수행하였다. 본 연구에서는 먼저 일본잎갈나무의 연도별 생장특성을 분석하기 위해 제5차 국가산림자원자료에서 수집된 일본잎갈나무의 연륜생장 자료를 정리하였다. 한편 일본잎갈나무의 연륜생장과 기후변수와의 관계를 구명하기 위해 1950년부터 2010년까지 정리된 월평균 기온과 월강수량 자료를 시군단위로 정리하였다. 기후조건의 유사성에 근거하여 일본잎갈나무의 시군별 연륜생장 자료를 군집분석한 결과 6 개의 기후 군집으로 구분할 수 있었다. 이와 함께 연륜생장 자료에 대한 크로스데이팅과 표준화 절차를 통해각 군집별 지표연대기를 제작하였다. 각 군집별 지표연대기의 적합성은 연륜생장의 평균민감도, 자기상관계수,신호 대 잡음비, 신호강도와 같은 기초통계량 분석을 통해 점검하였다. 최종적으로 각 군집별 일본잎갈나무의 연륜생장과 기후변수 간의 관계를 구명하기 위해 반응함수 분석을 실시하였다. 본 연구에서 얻어진 결과는 일본잎갈나무의 지역별 생장특성의 추정뿐만 아니라 기후변화에 따른 생장패턴의 변화 예측에 필요한 유용한 정보로 활용될 수 있을 것으로 기대된다. This study was conducted to analyze the effect of climatic variables on tree-ring growth of Larix leptolepis distributed in Korea by dendroclimatological method. For this, annual tree-ring growth data of Larix leptolepis collected by the 5th National Forest Inventory were first organized to analyze yearly growth patterns of the species. To explain the relationship between tree-ring growth of Larix leptolepis and climatic variables, monthly temperature and precipitation data from 1950 to 2010 were compared with treering growth data for each county. When tree-ring growth data were analyzed through cluster analysis based on similarity of climatic conditions, six clusters were identified. In addition, index chronology of Larix leptolepis for each cluster was produced through cross-dating and standardization procedures. The adequacy of index chronologies was tested using basic statistics such as mean sensitivity, auto correlation, signal to noise ratio, and expressed population signal of annual tree-ring growth. Response function analysis was finally conducted to reveal the relationship between tree-ring growth and climatic variables for each cluster. The results of this study are expected to provide valuable information necessary for estimating local growth characteristics of Larix leptolepis and for predicting changes in tree growth patterns caused by climate change.

관광지안내로봇용 위치인식 시스템에 관한 연구

임종환(Jong Hwan Lim) Korean Society for Precision Engineering 2012 한국정밀공학회지 Vol.29 No.7

The localization system for tour guide robot was developed which is inevitable and important for the guide robot in order to guide the tourists and explain the history or contents of the site. The localization system is based on the non-inertial sensors such as a DGPS, Dead-Reckoning. The information of the DGPS is used to update the estimated positions from Dead Reckoning. The extended Kalman filter was used for the fusion of the measured information from the sensors and estimated positions by Dead Reckoning. The simulation results show that it is very reliable and the position error is bounded within a certain extend.