주성분 분석을 이용한 펄스형 전자기장 자극을 통해 DNCB로 유발된 아토피성 피부염의 개선 효과 분석

이지영,김준영,이예린,김고은,이용흠,양세정,Lee, Jiyoung,Kim, Jun-Yong,Lee, Yerin,Kim, Ko Eun,Lee, Yongheum,Yang, Sejung 대한의용생체공학회 2021 의공학회지 Vol.42 No.3

Atopic dermatitis (AD), a chronic inflammatory skin disease, is characterized by itchy and age-dependent lesions. Previous studies have shown that pulsed electromagnetic field (PEMF) significantly improved chronic ulcers and ununited fractures, providing an evidence for the application of PEMF in resolving inflammation caused by AD. This study investigated the anti-inflammatory effect of PEMF on DNCB-induced AD in animal models. Five male hairless mice (6 weeks old) per group were assigned to a normal group, a sham group, and two PEMF groups (15Hz, 75Hz). Mice were treated with 2,4-Dinitrochlorobenzene (DNCB) to induce uniform AD among all groups excluding a normal group. To examine the inflammatory progress and the improvement of AD after the PEMF stimulation, images are taken with various cameras for non-invasive evaluation and the results are expressed using principal component analysis (PCA) for visualization. The results of this study demonstrated that PEMF effectively improved skin lesions without the use of drugs.

카메라 렌즈 평가용으로 제작된 nodal slide식 실시간 OTF 측정 장치

이지영,송종섭,조재흥,장수,임천석,이윤우,이인원,Lee, Ji-Young,Song, Jong-Sup,Jo, jae-Heung,Chang, Soo,Rim, Cheon-Seog,Lee, Yun-Woo,lee, In-Won 한국광학회 2002 한국광학회지 Vol.13 No.2

A real-time OTF (optical transfer function) measuring system with on- and off-axis nodal slide bench type for the camera lens is fabricated and evaluated. It consists of a nodal slide bench including a T-bar for the OTF measurement of an off-axis object, two dimensional CCD (charge coupled device) with pixel of 9.9${\mu}{\textrm}{m}$$\times$9.6${\mu}{\textrm}{m}$ for real-time OTF measurment, and a collimating lens of focal length of 300 mm for the optimization of this system. The OTF system is corrected by using the OTF of a SIRA lens of fnumber of F/8 and focal length 50 mm. In order to confirm the reliability of the OTF system, two MTFs (modulus transfer functions) of CCTV & VIDEO lens (JAPAN, AVENIR-SE 2514) of focal length of 25mm and field of view 10.6$^{\circ}$are measured by the camera bench type OTF system of reference OTF system and the nodal slide bench type OTF system and compared with each other. As a result, these two values are agree well with each other within 4% from 0 1p/mm to 100 1p/mm. 초측정 할 수 있는 nodal slide식 실시간 OTF 측정 장치를 제작하였다. 비축 물체를 측정하기 위하여 nodal slide와 T-bar를 사용하고, 실시간 측정을 위하여 화소 간격이 가로 9.9$\mu\textrm{m}$와 세로 9.6$\mu\textrm{m}$인 2차원 CCD(charge coupled device)를 사용하며, 초점 길이 300mm의 시준 렌즈를 사용하여 장치를 소형화하였다. 그리고 F/8, 초점 길이 50 mm인 SIRA사의 표준 렌즈를 이용하여 측정 장치의 정확도를 평가하고 보정하였다. 본 장치의 신뢰도를 위하여 시야각이 10.6$^{\circ}$이고, 초점 길이가 25.0mm인 CCTV & VIDEO 렌즈(JAPAN, AVENIR-SE 2514)의 MTF를 측정하여 카메라 벤취(bench)형 OTF측정 장치로부터 구한 MTF 값들과 상호 비교한 결과 대부분의 공간주파수에서 4% 이내로 일치하였다.

대용량 에너지 저장장치용 2세대 고온 초전도 코일의 특성해석

이지영,이세연,김영일,박상호,최경달,이지광,김우석,Lee, Ji-Young,Lee, Seyeon,Kim, Yungil,Park, Sang Ho,Choi, Kyeongdal,Lee, Ji-Kwang,Kim, Woo-Seok 한국전력공사 2015 KEPCO Journal on electric power and energy Vol.1 No.1

대용량 초전도 에너지저장장치(Superconducting Magnetic Energy Storage, SMES)용 초전도 권선을 제작하기 위해서는 높은 자장특성을 가고 있는 2세대 고온초전도 (2nd Generation High-Temperature Superconductor, 2G HTS) 선재를 사용하는 것이 효율적이다. 자기에너지 저장 밀도를 높이기 위해서는 권선에 높은 전류밀도를 인가해야 하는데, 도체의 평면에 수직 방향으로 인가되는 자속밀도가 커지면 임계전류가 작아지는 2세대 HTS 선재의 특성상 토로이드 형태의 권선을 구성하는 것이 일반적이다. 이러한 고온초전도 권선을 설계하기 위해서는 권선 특성의 정확한 해석이 필요한데 이를 위해 유한요소법을 사용한 프로그램을 이용하여 해석이 가능하나 토로이드 형태의 권선은 대칭성의 문제로 3차원 해석을 해야만 하며, 이는 모델링에 많은 어려움과 높은 컴퓨터 사양, 그리고 매우 긴 계산 소요시간이 필요함을 의미한다. 본 논문에서는 이러한 문제점을 해결하기 위해 분석적이고 통계적으로 고온 초전도 코일에서 작용하는 최대 수직자장과 저장된 에너지를 결정하는데 이해하기 쉽고 효율적으로 계산하는 방법을 제시했다. 이 방법은 현저한 시간단축과 효율적인 설계를 할 수 있는 새로운 계산 방법으로 기존의 유한요소법에 의해 소요되는 계산 시간에 비해 1/1000정도로 계산시간 단축을 할 수 있었다. Large scale superconducting magnetic energy storage (SMES) system requires very high magnetic energy density in its superconducting coils to enhance the energy capacity and efficiency of the system. The recent high temperature superconducting (HTS) conductors, so called 2G conductors, show very good performance under very high magnetic field so that they seem to be perfect materials for the large scale SMES coils. A general shape of the coil system with the 2G HTS conductor has been a tor oid, because the magnetic field applied perpendicularly to the surface of the 2G HTS conductor could be minimized in this shape of coil. However, a toroid coil requires a 3-dimensional computation to acquire the characteristics of its critical current density - magnetic field relations which needs very complicated numerical calculation, very high computer specification, and long calculation time. In this paper, we suggested an analytic and statistical calculation method to acquire the maximum magnetic flux density applied perpendicularly to the surface of the 2G HTS conductor and the stored energy in the toroid coil system. Although the result with this method includes some errors but we could reduce these errors within 5 percent to get a reasonable estimation of the important parameters for design process of the HTS toroid coil system. As a result, the calculation time by the suggested method could be reduced to 0.1 percent of that by the 3-dimensional numerical calculation.

역전파 알고리즘을 이용한 경계결정의 구성에 관한 연구

이지영,Lee, Ji-Young 한국정보기술전략혁신학회 2005 情報學硏究 Vol.8 No.1

The Back propagation algorithm is a very effective supervised training method for multi-layer feed forward neural networks. This paper studies the decision boundary formation based on the Back propagation algorithm. The discriminating powers of several neural network topology are also investigated against five manually created data sets. It is found that neural networks with multiple hidden layer perform better than single hidden layer.

디지털이미지 기록관리를 위한 메타데이터 요소 연구

이지영,김희정,Lee, Ji-Young,Kim, Hee-Jung 한국과학기술정보연구원 과학기술정보센터 2009 Journal of Information Science Theory and Practice Vol.40 No.4

공공기관 내에서의 전자기록물의 중요성과 비중이 높아져감에 따라 다양한 형태의 기록물 관리의 필요성이 대두되고 있다. 2007년 제안된 국가기록원의 기록관리 메타데이터 표준안의 요소들은 주로 텍스트 형태의 기록물에 중점을 두고 있으므로 다양한 유형의 전자기록물을 표현할 수 있는 요소의 확장이 필요하다. 이에 본 연구에서는 이미지 기록물에 초점을 맞추어 메타데이터 요소들을 제안하였다. 이를 위하여 이미지 기록의 특성을 파악하였고, 최근에 그 개정판이 제공 된 호주 국가기록원의 Australian government recordkeeping metadata standard와 PREMIS 데이터사전과 요소들을 비교분석하였다. 이를 통하여 포맷(format), 중요속성(significant properties), 환경(environment), 범위(coverage)등의 네 요소의 수정 및 추가를 제안하였다. As the importance and proportion of electronic records increases in the public sector, the necessity for variable types of records management has strengthened. Elements of records management metadata standards, which were provided in 2007 by the National Archives of Korea, focused mainly on text-centered records management standards. Therefore an extension of elements which can represent diverse types of electronic records is needed. In this study, metadata elements focusing on image records are suggested. For this, the characteristics of image records are investigated and the Australian government recordkeeping metadata standard and the PREMIS data dictionary, which have been recently modified, are analyzed. Through this, four elements, format, significant properties, environment, and coverage are suggested to fortify the current records management standard.

성장 장애에 관한 임상 연구의 최근 동향 -최근 중의 잡지를 중심으로-

이지영,정민정,최지명,유선애,이승연,Lee, Ji-Young,Jeong, Min-Jeong,Choi, Ji-Myuoung,Yu, Sun-Ae,Lee, Seung-Yeon 대한한방소아과학회 2007 대한한방소아과학회지 Vol.21 No.1

Objectives : The aim of this study was to investigate the treatment of failure to thrive in current Traditional Chinese Medical Journals. Methods : To figure out the failure to thrive, Chinese Medical Journals from China National Knowledge Infrastructure(CNKI) which was published in 1994 to 2005 were analyzed. 矮(小)-whae(so) was searched. Results : Eleven articles were selected. 5 of them were used herbal medicine, and were showed that the total improvement rate was higher than 70% in failure to thrive. 2 of them were used acupuncture, and the last of them were used a therapy of combining Traditional Chinese Medicine with western medicine. Conclusions : The Oriental medical treatments for failure to thrive were presumed to be effective in most articles. But we think that the more studies are needed.

코호넨의 자기조직화 구조를 이용한 클러스터링 망에 관한 연구

이지영,Lee, Ji-Young 한국정보기술전략혁신학회 2005 情報學硏究 Vol.8 No.1

Learning procedure in the neural network is updating of weights between neurons. Unadequate initial learning coefficient causes excessive iterations of learning process or incorrect learning results and degrades learning efficiency. In this paper, adaptive learning algorithm is proposed to increase the efficient in the learning algorithms of Kohonens Self-Organization Neural networks. The algorithm updates the weights adaptively when learning procedure runs. To prove the efficiency the algorithm is experimented to clustering of the random weight. The result shows improved learning rate about 42~55% ; less iteration counts with correct answer.

모바일 클라이언트-서버 모델에 관한 연구

이지영,Lee, Jie-Young 한국정보기술전략혁신학회 2009 情報學硏究 Vol.12 No.1

In this paper, we aim that it solve to problem of the database hoarding because a week connectivity of wireless networks and cutting of link, Consistency of shared data, optimizing of the log include to Mobile Continuous Query Processing System under the mobile client and server environment. and we demonstrate of the superiority for the new Mobile Continuous Query Processing System compare C-I-S(Client-Intercept -Server)model with performance. and we perform to various experiment in order to establishment of superiority compare the index architecture and method for the realtime Continuous Query Processing. in this paper.

음악치료(音樂治療)의 원리(原理)와 체질의학적(體質醫學的) 접근을 위한 검토

이지영,박성식,Lee, Ji-Young,Park, Seong-Sik 사상체질의학회 2006 사상체질의학회지 Vol.18 No.1

1. Objectives The present study purposed to examine the contents and the principles of music therapy according to Oriental medicine theories in order to prove that music therapy is not a new research area but its principle is found in the long tradition of Oriental medicine. 2. Methods We investigate the possibility of music therapy based on Oriental medicine theories and examine the meanings of music therapy from the viewpoint of Oriental medicine. 3. Conclusions and discussions (1) The principles of music therapy are the principle of homogeneity, catharsis and balance. (2) When one’s mind changes, there are naturally occurred sounds, which are called Oseong (五聲: the oriental five voices exhalation, laughing, singing, wailing and groaning), and the notes defined by arranging the Oseong according to the principle of Ohaeng (五行: the oriental five phases wood, fire, earth, metal, water) are Oheum (五音: the oriental five musical notes Gakeum, Chieum, Gungeum, Sangeum and Wooeum.). If Eum (musical notes) is classified into Ohaeng, it can be divided into Gakeum, Chieum, Gungeum, Sangeum and Wooeum. (3) Change of Sinji (神志: consciousness) induces change of Gigi (氣機: function of Gi), which can change the character of voices. Oseong controls the functions of Ojang (五臟: the oriental five viscera) by ruling one’s Jeongji (情志: emotion). It can reduce the damage of the viscera caused by excessive vent of emotion resulted from unconscious expression of Oseong - Hoseong (呼聲: exhalation), Soseong (笑聲: laughing), Gaseong (歌聲: singing), Gokseong (哭聲: wailing) and Sinseong (呻聲: groaning). (4) Yijeongseungjeong (以情勝情: Control emotion with emotion) therapies, which suppresses an emotion by stimulating another, include Noseungsabeop (怒勝思法: Control anxiety with anger), Heeseungbibeop (喜勝悲法: Control sorrow with joyfulness), (思勝恐法: Control fear with anxiety), Biseungnobeop (悲勝愁法: Control anger with sorrow) and Gongseungheebeop (恐勝喜法: Control joyfulness with fear). (5) Seongeum (聲音: voices and musical notes) can be applied to a stimulation method that not only harmonizes the rhythm of living organs but also controls the occurrence of diseases caused by mutual Pyeonseongpyeonsoi (偏盛偏衰: relative preponderance and weakness) through direct induction of the strength and weakness of Gi function of the oriental five viscera in a human body according to the individual character. Sounds preferred by the patient, the material of an instrument selected by the patient, the character of rhythm and music expressed by the patient and the sound or voice uttered frequently by the patient can be considered in diagnosis and treatments for the patient’s body and mind.

알츠하이머병 환자에서 행동심리증상의 성별차이

이지영,임우영,김현,이강준,Lee, Ji Young,Im, Woo-Young,Kim, Hyun,Lee, Kang Joon 한국정신신체의학회 2014 정신신체의학 Vol.22 No.2

연구목적 알츠하이머병 환자들의 행동심리증상(BPSD)은 임상적인 문제들을 일으켜 결국 기능의 감퇴, 간병인 스트레스, 입원, 사망률의 증가를 가져온다. 최근의 연구는 성별차이가 BPSD에서 중요한 역할을 한다고 보고하고 있으나, BPSD와 성별 사이 연관에 대한 국내 연구는 시행된 적이 없었다. 이에 본 연구는 알츠하이머병 환자들의 BPSD가 성별 차이에 의해 영향을 받는 것인지를 검증해 보고자 실시하였다. 방 법 면담과 인지기능평가를 통해 DSM-IV 진단기준에 의하여 알츠하이머병으로 진단받은 98명의 환자들이 본 연구에 참가하였다. 간이정신상태검사(MMSE), 임상치매평가척도(CDR), 전반적 퇴화척도(GDS), 한국형 신경정신행동검사(K-NPI)를 사용하여 인지기능 및 BPSD를 평가하였다. 성별 차이를 확인하기 위해서 독립 t 검증을 사용하여 분석하였으며, MMSE, CDR, GDS와 NPI 사이의 관련성을 살펴보기 위해 피어슨 상관분석을 사용하였다. 결 과 알츠하이머병 환자들의 BPSD에서 통계적으로 유의미한 성별 차이는 관찰되지 않았다. MMSE와 NPI 총점, 그리고 NPI 하위영역인 환각과 유의한 상관관계를 보였으며, CDR의 경우 NPI 총점, 무감동/무관심, 과민/불안정과, GDS의 경우 NPI 하위영역인 환각과 유의한 상관관계를 나타내었다. 결 론 본 연구결과 우리나라 알츠하이머병 환자들의 BPSD에서 성별의 차이는 나타나지 않았지만, 추후 알츠하이머형 치매의 BPSD가 성별 차이에 의한 것인지 혹은 개인 차에 의한 것인지를 더 명확하게 밝혀내기 위한 광범위하고 지속적인 연구가 필요할 것으로 생각된다. Objectives : Behavioral and psychological symptoms of dementia(BPSD) represent significant clinical problems, resulting in functional decline, caregiver distress, institutionalization and increased mortality. A recent study showed gender differences have important role in the development of BPSD, but relationship between BPSD and gender has never been studied in Korea. This study was designed to examine whether patients with Alzheimer's disease show gender differences in behavioral and psychological symptoms of dementia(BPSD). Methods : Ninety-eight subjects with Alzheimer's disease were included in this study. We carried out history taking and cognitive assessment for the diagnosis of Alzheimer's disease based on DSM-IV. Cognitive impairment and BPSD were measured using the Mini Mental State Examination(MMSE), Global Deterioration Scale (GDS), Clinical Dementia Rating(CDR) and the Korean Neuropsychiatric Inventory(K-NPI). Independent samples t-test was used to examine the differences across gender in BPSD. Correlation analysis between MMSE, CDR, GDS and NPI was performed using Pearson's correlation coefficient. Results : There were no significant gender differences between the gender in BPSD. We found statistically significant negative correlations between MMSE with NPI total score, and with scores of several sub-domains such as hallucination. Conclusions : This study showed that gender differences in BPSD are not significant. Further research is necessary to identify whether BPSD affect gender differences or individual differences.