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      • 테트라데카헤드론구조를 가지는 인공디스크의 강성 해석

        이유미(Y. Lee),김현영(H.Y. Kim),이재홍(J.H. Lee),김광원(K.W. Kim),김두만(D.M. Kim) 대한기계학회 2012 대한기계학회 춘추학술대회 Vol.2012 No.11

        An artificial disc used for Total Disc Replacement(TDR) should not be constrained in any degree of freedom in order to behave like a real one. It also has to be able to withstand compression, flexion and torsion during vertebral joint movement. Artificial discs currently in use have made from various materials for different purposes and also had complex structures. To improve and simplify, an artificial disc was made of cellular structure; the basis cell is a fourteen-sided tetradecahedron. The model was filled with tetradecahedrons between the two plates. In this paper, the two discs, the real disc and cellular structured one, were compared with properties using ABAQUS/standard in following compression, flexion and torsion.

      • KCI등재

        한국인 골반내 장기 탈출 환자에서 실리콘 환 페사리의 이용

        김진홍 ( J. H. Kim ),이유미 ( Y. M. Lee ),김은중 ( E. J. Kim ),정기욱 ( K. W. Chung ),권동진 ( D. J. Kwon ),유영옥 ( Y. O. Lew ),김도강 ( D. K. Kim ),김수평 ( S. P. Kim ) 대한산부인과학회 1997 Obstetrics & Gynecology Science Vol.40 No.12

        Pessaries have been used for centuries in the management of pelvic organ prolapse. Although surgical repair has been popularized by surgeons and gynecologists for younger women with pelvic relaxation, pessaries remain a useful palliative strategy for patients who refuse surgery as represent higher operative risks. Methods: Due to the recent advancement of material science, medical-grade silicone has replaced the traditional rubber, plastic, or Lucite, since it is more durable and non-allergenic. The authors used silicone ring pessaries in 98 Korean women with pelvic organ prolapse compromising those who are at high risks for anesthesia because of medical disease, who want to conceive in the further or those who wish to avoid surgical therapy. Results: 1. The average age of patients is 62.69±11.37 years. Period of pelvic organ prolapse is 78.64±56.23 months and duration of pessary insertion is 17.34±11.75 months. 2. The average time point of first complication was 7.91±4.25 months. The time point of complication of user group and non-user group of estrogen and lubricant was 10.06±3.31 months and 4.13±3.27 months, respecitively, which shows that complication occurred later in user group than in non-user group. 3. Pessary with support(16 out of 43 patients, 37.2 %) shows more serious complications (ulceration of vaginal wall) than pessary without support(1 out of 37 patients, 2.7 %). 4. The pessary sizes that fit best the prolapsed uteri of Korean women are #3(diameter of 63.5 mm) and #4(diameter of 69.8 mm) (60 out of 77, 77.9 %). Natural correction rate after removal of pessary(pessary insertion period: over 1 year) was 22.7 %(10 out of 44). 5. The most common complication in patient with uterine prolapse with or without cystocele is erosion. On the other hand ulceration of vaginal wall is the most common complication in those with rectocele and cystocele. 6. Among patients with pelvic organ prolapse in Korea, when there was uterine prolapse only, #3 and #4 pessary without support was the most commonly used(22 of 35, 62.9 %). When uterine prolapse was accompanied with rectocele or cystocele, #3 and #4 pessary with support fitted the best (accompanied with cystocele only: 14 of 26, 53.8 %, accompanied with cystocele and rectocele: 8 fo 9, 88.9 %). Conclusion: The above results suggest that we could recommend more utilization of proper shaped and sized pessary of patients with pelvic organ prolapse along with regular follow-up examination and proper use of estrogen, Trimosan, antibiotics, and anti-inflammatory drugs, in place of surgical therapy as the population of old aged women increases. Furthermore, education of the old aged women who are reluctant to visit Dr`s office how to do self-fitting the pessary will result in time saving and reduction of medical costs.

      • 한국 성인에서 비알콜성 지방간의 중증도에 따른 대사이상의 특징

        김형진,김대중,김수경,김세화,이유미,안철우,차봉수,송영득,임승길,김경래,이현철,허갑범 대한내분비학회 2002 Endocrinology and metabolism Vol.17 No.4

        연구배경: 30세 이상의 성인 한국인에서 지방간의 중증도와 대사증후군의 여러 요소들 (특히 인슐린저항성 및 중심성비만)과의 관련성을 분석하고자 하였다. 방법: 대상자는 2001년 4월부터 6월까지 건강검진센터를 방문한 사람들 중 만성 바이러스성 간염이나 일주일에 2회 이상 음주력이 있는 사람들을 제외한 1074명 (남자 502, 여자 572)에서 문진, 신체검사, 채혈 그리고 복부초음파를 시행하였다. 결과: 1074명중 522명에서 지방간이 양성이어서 양성율은 49%였으며 남성은 여성에 비해 높은 유병률을 보였다. (57 vs 42%, p<0.05). 당뇨병, 비만 그리고 이상지질증을 가지지 않은 사람들에서 비알콜성 지방간의 유병률은 20%였다. 지방간이 양성인 522명중 218명은 경도, 273명은 중등도, 31명은 중증의 지방간 소견을 보였다. 체질량지수, 허리둘레, 체지방률, 수축기혈압, aspartate aminotransferase, alanine aminotransferase, 총콜레스테롤, 중성지방, 그리고 총콜레스테롤/고밀도지단백 비는 지방간의 중증도에 따라 의미있게 증가하는 양상을 보였다(p<0.05). 다중회귀분석을 시행하였을 때 지방간의 중증도를 잘 반영하는 인자로는 허리둘레, alanine aminotransferase, HONA_IR, 총콜레스테롤/고밀도지단백비, aspartate aminotransferase, 그리고 수축기혈압의 순서로 나타났다. 공복혈당장애, 고혈압 및 인슐린저항성은 지방간을 가진 군에서 대조군보다 의미있게 높은 빈도를 보였을 뿐만 아니라 지방간의 중증도에 따라 차이를 보였다(p<0.05). 인슐린저항성은 심한 지방간에 비교위험도가 14.7(CI; 6.8∼32.0), 중등도의 지방간에서 6.9(CI; 4.6∼10.3), 경도의 지방간에서 5.7(CI; 3.6∼8.8)이었으며 HOMA_IR의 상위 1/4을 인슐린저항성이 있는 군으로 정의하였을 때 각군에 인슐리저항성을 가진 비율은 7.6, 32.0, 36.0, 그리고 55%였다(p<0.05). 지방간의 중증도에 따른 비알콜성 지방간염의 고위험군 비율은 각각 5.0, 21.6, 27.8, 그리고 58.1%였다(p<0.05). 결론: 우리나라의 비알콜성 지방간의 빈도는 서구인에 비해 높은 것으로 나타났다. 또한 비알콜성 지방간이 있을 경우 대사증후군과 관련된 여러인자들(특히 인슐린저항성과 중심성비만)과 비알콜성 지방간염의 위험이 현저히 증가하며 초음파의 중증도 분류에 따라 비례하였다. Background: We evaluated the frequency of non-alcoholic fatty liver disease, and the associations between the metabolic abnormalities and severity of non-alcoholic fatty liver disease in Korean adults using ultrasonography. Methods: We examined 1074 Korean adults above the age of 30 years, comprising of 502 men and 572 women, participating in medical check-ups at the Health Promotion Center. Hepatitis B and C serologies were negative, and the average weekly alcohol intake was ≤ 2 standard drinks. A standard interview, physical exam and biochemical study, were conducted, and an experienced operator carried out ultrasound liver studies. Results: 522 of the subjects had non-alcoholic fatty liver disease, and the remaining 552 did not. The frequency in the men was higher than that in the women (57 vs 42%, p<0.05). The frequency of non-alcoholic fatty liver disease in the subjects without diabetes, obesity or dyslipidemia was 20%. We classified subjects into 4 groups: the controls (n=552) and those with mild (n=218), moderate (n=273) or severe fatty liver disease (n=31), according to their ultrasonographic findings. BMI, waist circumference, body fat, systolic blood pressure, aspartate aminotransferase, alanine aminotransferase, total cholesterol, triglyceride, the total-to HDL-cholesterol ratio, impaired fasting glucose, hypertension and insulin resistance, were all significantly increase with the increased severity of non-alcoholic fatty liver disease (p<0.05). Following the multiple regression analyses, waist, alanine, aminotransferase, HOMAIR, the total- to HDL-cholesterol ratio, aspartate aminotransferase and systolic blood pressure, were all associated with the severity of non-alcoholic fatty liver disease. Odd ratios of insulin resistance in the mild, moderate and severe non-alcoholic fatty liver disease were 14.7 (CI: 6.8∼32.0), 6.9 (CI: 4.6∼10.3) and 5.7 (CI 3.6∼8.8), respectively. The percentages of subjects with insulin resistance in each group were 7.6, 32.0, 36.0 and 55.0% (p<0.05), respectively. The percentages of subjects with risk of non-alcoholic steatohepatits in each groups were 5.0, 21.6, 27.8 and 581% (p<0.05) respectively. Conclusion: The frequency of non-alcoholic fatty liver disease was relatively high in Korean adults. Proportional differences in metabolic abnormalities, relation to the severity of non-alcoholic fatty liver disease, were found by ultrasonography (J Kor Soc Endocrinol 17:514∼525, 2002).

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