In vivo와 in vitro 에서 양극산화 처리한 타이타늄 시편의 상대적인 생체적합성 평가

이유미,이은정,염동선,김도순,이성태,김병일,조현욱,Lee Yu-Mi,Lee Eun-Jung,Yeom Dong-Sun,Kim Do-Soon,Yee Sung-Tae,Kim Byung-Il,Cho Hyun-Wook 한국생명과학회 2006 생명과학회지 Vol.16 No.2

처리하지 않은 타이타늄과 양극 산화 처리한 타이타늄 시편의 생체적합성을 평가하기 위해, 시편을 마우스의 복부 피하 조직에 이식하고 2주 동안 생존시켰다. 그 시편에 대한 복부 피하 결합조직의 반응을 조직학적으로 조사하였다. 시편 주위를 둘러싸는 섬유성 결합조직 막이 관찰되었으며 이 막은 섬유모세포, 섬유세포 및 기타 세포로서 중성호성백혈구, 대식세포, 거대다핵세포 등으로 이루어져 있었다. 시편을 둘러싸는 이 막에 새로이 형성된 혈관이 존재하기도 하였다. 임플란트와 접하는 섬유성 막에 거대다핵세포가 관찰되었다. 섬유성 막에 있는 세포 종류와 막의 두께를 조사하였다. 막에 있는 대부분의 세포는 섬유모세포와 섬유세포이었다. 양극 산화 처리를 하지 않은 타이타늄 시편에 비해 산화 처리를 한 시편을 둘러싸는 섬유성 막의 평균 두께가 더 얇았다. 또한 타이타늄 시편의 생체적합성을 세포 배양법으로 조사하였다. 산화 처리를 한 시편 위에서 배양한 MG-63 세포의 수가 유의하게 증가되었다. 이런 결과들은 in vivo 와 in vitro 실험에서 산화 처리를 한 타이타늄 시편이 생체적합성을 증가시키는데 효과적이라는 것을 말해준다. To evaluate the biocompatibility of untreated and anodized titanium specimens, the specimens were implanted in the subcutaneous tissue of the abdominal region of female mice for two weeks. The reaction of connective tissue to specimens was histologically studied. The implants were encapsulated by fibrous connective. tissue consisting of fibroblast, fibrocyte and other cellss including neutroophil, macrophage and giant multinucleated cell. some newly formed blood vessels were located in the fibrous capsule surrounding the implant. Giant multinucleated cells were observed at the fibrous capsule adjacent to the implant. Kind of cell types and the thickness of fibrous capsules were examined quantitatively. Most of cell types located in the fibrous capsule were fibroblast and fibrocyte. The average thickness of fibrous capsules for the anodized specimens was much thinner than that of the untreated titanium specimen. Biocompatibility of titanium specimens were also studied by using cell culture method. The number of MG-63 cells was significantly increased on the anodized titanium specimens in vitro experiment. Our observations suggest that anodized titanium specimens are more effective for the improvement of biocompatibility in vivo and in vitro.

산림정보 - 밤이면 잠자는 연꽃 닮은 '물의 요정'

이유미,Lee, Yu-Mi 한국산림경영인협회 2010 山林經營 Vol.197 No.-

산림정보 - 꿈같은 열매 "월귤"

이유미,Lee, Yu-Mi 한국산림경영인협회 2010 山林經營 Vol.197 No.-

십이지장 폐쇄를 동반한 선천성 식도 폐쇄에 대한 고찰

이유미,남소현,김대연,김성철,김인구,Lee, Yu-Mi,Nam, So-Hyun,Kim, Dae-Yeon,Kim, Seong-Chul,Kim, In-Koo 대한소아외과학회 2008 소아외과 Vol.14 No.1

There is significant morbidity and mortality associated with the combination of esophageal atresia (EA) and duodenal atresia (DA). Nevertheless, the management protocol for the combined anomalies is not well defined. The aim of this study is to review our experience with the combined anomalies of EA and DA. From May 1989 to August 2006, seven neonates were diagnosed as EA with DA at Asan Medical Center. In all cases, the type of EA was proximal EA and distal tracheoesophageal fistula (TEF). The diagnosis of DA was made in theprenatal period in 1, at birth in 4, 4 days after birth in 1 (2 days after EA repair) and at postmortem autopsy in 1. Except the one case where DA was missed initially, primary simultaneous repair was attempted. DA repair with gastrostomy followed by EA repair in 2, EA repair followed by DA repair without gastrostomy in 2, and TEF ligation followed by DA repair with gastrostomy in 1. There were two deaths. One baby had a large posterolateral diaphragmatic hernia, and operative repair was not attempted. The other infant who had a TEF ligation and DA repair with gastrostomy expired from cardiac failure due to a large patent ductus arteriosus. Simultaneous repair of EA and DA appears to be an acceptable management approach for the combined anomalies, but more experience would be required for the selection of the primary repair of both anomalies.

산림경영: 산림정보 -층층이 달린 꽃송이 따라 은은한 향기

이유미,Lee, Yu-Mi 한국산림경영인협회 2011 山林經營 Vol.199 No.-

산림경영 - 산림정보

이유미,Lee, Yu-Mi 한국산림경영인협회 2012 山林經營 Vol.204 No.-

분무열분해법으로 YAG:Ce 제조시 용액 조건이 발광특성에 미치는 영향

이유미,강태원,정경열,Lee, You-Mi,Kang, Tae-Won,Jung, Kyeong-Youl 한국분말야금학회 2012 한국분말재료학회지 (KPMI) Vol.19 No.3

YAG:Ce yellow phosphor particles were synthesized by spray pyrolysis with changing the solution properties and their luminous properties, crystal structure, and morphological changes were studied by using PL measurement, XRD, and SEM analysis. It was clear that the solution properties significantly affected the crystal phase, crystallite size, the PL intensity, and the morphology of YAG:Ce particles. At low calcination temperature, the addition of urea only to the spray solution was helpful to form a pure YAG phase without any impurity phases, as the result, the highest luminescence intensity was achieved at the calcination temperature of $900^{\circ}C$. When the calcination temperatures were larger than $1300^{\circ}C$, however, the YAG particles prepared without any additive showed the highest luminescent intensity. Regardless of the solution conditions, the emission intensity of YAG:Ce particles prepared by spray pyrolysis showed a linear relation with the crystallite size. In terms of the morphology of YAG:Ce particles, the addition of both DCCA and $NH_4OH$ to the spray solution was effective to prepare a spherical and dense structured YAG particles.

인산염의 첨가와 침지가 저지방 소시지의 냉장저장 중 품질과 저장성에 미치는 영향

이유미,진구복,Lee, Yu-Mee,Chin, Koo-Bok 한국축산식품학회 2012 한국축산식품학회지 Vol.32 No.1

This study was performed to determine the quality characteristics and shelf-life of low-fat sausages (LFS) with 0.4% sodium tripolyphosphate (STPP) alone or in combination with a 10% trisodium phosphate (TSP) solution during refrigerated storage. When 0.4% STPP was added, no differences in pH values were observed. However, pH values increased with the addition of the TSP solution when 0.4% STPP was incorporated. The addition of STPP into LFS decreased redness and the dipping in the TSP solution increased yellowness (p<0.05). Total bacteria and Listeria monocytogenes, which inoculated Log $10^{3-4}$ colony forming units (CFU/g) were increased with increased storage time. At 4 wk of storage, total bacteria and Listeria monocytogenes reached levels of 8.03-8.22 Log CFU/g, however they decreased to 7.89 Log CFU/g at 8 wk of storage time. Due to the pH increases, Listeria monocytogenes significantly increased in LFS dipping with 10% TSP. Based on these results, LFS dipping with 10% TSP solution promoted the growth of Listeria monocytogenes, regardless of STPP addition. These results indicated that 0.4% STPP addition and dipping with TSP affected the pH and color, however, it didn't extend the shelf-life of LFSs during refrigerated storage. 본 연구는 인산염의 첨가와 침지가 저지방 소시지의 저장기간에 따른 품질 및 저장성을 평가하기 위해 실시하였다. 저지방 소시지에 0.4% STPP를 첨가하고, 10% TSP 용액에 침지함에 따라 pH값이 증가하였다. STPP의 첨가에 따라 적색도가 감소하는 반면, 10% TSP 침지구의 황색도는 증가하였다(p<0.05). 저장기간이 경과함에 따라 명도는 유의적으로 감소한 반면 적색도는 유의적으로 증가하였다(p<0.05). 약 5 Log CFU/g로 접종된 Listeria monocytogenes(LM) 균수는 저장기간이 경과함에 따라 4주에 8.03-8.22 Log CFU/g로 나타났고 8주에는 7.89 Log CFU/g로 약간 감소했다. 접종된 저지방 소시지의 저장 중 총균과 LM균의 성장은 10%의 TSP 침지에 의해 pH의 증가로 유의적으로 더 촉진된 것으로 판단된다. 이와 같은 결과를 종합하면 인산염 첨가 및 침지는 pH와 색도(명도와 황색도)에 영향을 주었으며 저장기간 중 뚜렷한 항균 및 항산화 효과는 없었다.

책갈피산책 - "욕망의 식물학"

이유미,Lee, Yu-Mi 대한출판문화협회 2002 출판저널 Vol.319 No.-

파노라마 및 정모방사선사진을 이용한 저작형태에 따른 안면비대칭에 관한 연구

이유미,김재창,Lee, You-Mee,Kim, Jae-Chang 대한안면통증구강내과학회 2006 Journal of Oral Medicine and Pain Vol.31 No.2

Recent studies have shown that there are significant increasing facial asymmetry using 3-dimensional imaging. This study use panorama view and PA cephalograph that were low in price and make good use in dentistry. For this study, 35 persons without remarkable malocclusion were selected, they had panorama view and PA cephalograph, make written questionnaire about facial asymmetry cognition and masticatory pattern. Data obtained were statistically processed by the SPSS Windows program and the results of this study were as follows: 1. There were significant difference between Rt and Lt. on Co-Go, Co-Ag, Co-Go-Ag, Go-Me- Ag. 2. In panorama view, There were significant difference between Rt. and Lt Co-Ag that chewing right side, Rt. and Lt. Co-Go that chewing left side, 3. In PA cephalograph view, There were significant difference in Rt. and Lt. Cg-Go, Rt. and Lt. Co-Ag that chewing right side, Rt. and Lt. Cg-Go that chewing left side 4. There were significant difference in Rt. and Lt. Co-Go, CO-si-CR, go-ME-Ag that cogniting facial asymmetry.