랫트 뇌에서의 galectin-3의 검출

이유경,강해은,우희종,Lee, Yoo-Kyoung,Kang, Hae Eun,Woo, Hee Jong 대한수의학회 2004 大韓獸醫學會誌 Vol.44 No.1

Galectin family, endogenous ${\beta}$-galactoside-binding animal lectins, is known for the role in cell differentiation, morphogenesis, apoptosis and tumorigenesis. Galectin-3, one of family member, has been studied for its role in cell differentiation and tumor metastasis, and for its expression on epithelial cells of colon and mast cells but not in brain. Several reports, however, suggest its expression in brain including as a prion binding protein. In this report we explored possibility of galectin-3 expression in brain tissue. With Western blot and RT-PCR with rat brain tissues, we could detect galectin-3 that was not shown by conventional immunohistochemistry. Our results indicated galectin-3 was expressed in brain, and substantiate the previous report on galecin-3 as a prion-related protein in brain.

발열성 물질시험과 세균 내독소 시험의 비교 연구

이유경(Yoo Kyoung Lee),강윤숙(Yoon Sook Kang),백선영(Sun Young Baek),김용관(Yong Kwan Kim),신광훈(Kwang Hoon Shin),민홍기(Hong Ki Min) 대한약학회 1999 약학회지 Vol.43 No.5

To survey the possibility of replacing the pyrogen test with Limulus Amebocyte Lysate (LAL) test and to find out a standard methods suitable to our blood products made in Korea, 100 samples of 20% human serum albumin were tested by commercial LAL test kits and results of those were compared with rabbit pyrogen test. The LAL test is used both kinetic-chromogenically and kinetic- turbidimetrically. Both methods equally showed broad detection range (5.0~0.005EU/ml), excellent sensitivity (>/-0.005EU/ml) and predominant recovery rate within valid dilution range, but kinetic-turbidimetric method seemed to be more reproducible than kinetic-chromogenic method(kinetic-chromogenic method : S.D.=15.88, kinetic-turbidimetric method : S.D.=8.12). After heating the sample at 75oC for 15min, the results showed a little elevated recovery rate with both methods. After performing the test on 100 albumin samples with both kits, the results were analysed using the USP stadard (1.33EU/ml). 7% of samples in kinetic-chromogenic methods and 1% of samples in kinetic-turbidimetric method exceeded the limit of endotoxin levels regulated for blood products in USA. Because this phenomenon was not observed in both methods at the same time and both methods have high sensitivity (>/-0.005EU/ml), these results seemed to depend on non-specific reaction. Considering its sensitivity and reproducibility, we could assure that LAL test is proper to detecting pyrogenic with good sensitivity.

효율적인 하천관리를 위한 하천생태 특성을 고려한 유형 분류 -낙동강수계를 대상으로-

이유경 ( Yoo Kyoung Lee ),이상우 ( Sang Woo Lee ) 한국환경복원기술학회(구 한국환경복원녹화기술학회) 2012 한국환경복원기술학회지 Vol.15 No.5

외국인 학습자의 한국어 어휘의 의미 사용 연구 - 이동 동사 ‘가다’를 중심으로-

이승연 ( Lee Seung-yeon ),이유경 ( Lee Yoo-kyoung ) 우리어문학회 2020 우리어문연구 Vol.67 No.-

본 연구는 외국인 학습자가 한국어 어휘의 다의적 의미를 사용하는 양상을 살피는 것을 목적으로 한다. 연구를 위해 학습자 말뭉치(국립국어원)에서 이동동사 ‘가다’의 용례를 수집, 정련하여 총 4,814개의 용례를 확보하였으며, 한국어 사전의 ‘가다’ 항목에 실린 의미들을 종합적으로 분석하여 43개의 의미 유형으로 의미 주석을 실시하였다. 연구 결과 초급에서는 43개 의미 중 총 12개의 의미가 사용되었으며 주로 ‘가다’의 기본 의미인 ‘한곳에서 다른 곳으로 장소를 이동하다(70.67%)’에 사용이 집중되어 있었다. 중급에 이르면 총 20가지 의미 유형이 나타나는데, 이 가운데 기본 의미의 비중은 54.08%로 다소 감소하고 ‘추상적 이동(9.23%)’, ‘신분의 변화(5.33%)’ 등의 사용이 늘기 시작한다. 고급에 이르면 총 31가지 의미 유형이 나타나 의미 사용 범위가 매우 넓어진다. 의미 내용 역시 ‘개인이나 사회의 이념, 가치, 관점 등의 이동’과 같이 매우 추상화된 의미로 확장됨을 알 수 있다. 이상의 내용을 요약하면 다음과 같다. 첫째, 학습자의 숙달도가 높아지면서 하나의 어휘를 맥락에 따라 다양한 의미로 사용하는 능력도 발달한다. 둘째, 이러한 의미의 확장은 구체성을 지닌 의미에서 추상화되는 방향으로 이행된다. 이러한 결과는 기존의 연구 결과에서 학습자의 숙달도가 의미 확장에 크게 영향을 미치지 못한다고 한 주장과 대비된다. This paper investigates the aspects that occur in the process of Korean language learners using multiple meanings of a polysemic word. For this research, we collected the usage of ‘kata’ as a locomotive verb from learner corpus (National Institute of Korean Language), refined and secured a total of 4,814 usages. By analyzing the meanings of ‘kata’ within the Korean dictionary, we were able to develop a framework for semantic annotation. The result of the research indicated that 12 meanings out of total 43 were adopted in the beginner’s level, where the use of ‘kata’ was focused on its basic meaning ‘to move from one place to another (70.67%)’ In the intermediate level, a total of 20 different types of meaning appeared. The percentage of the basic meaning decreased to a degree, taking up 54.08% whereas its use depicting ‘abstract movement (9.23%)’ and ‘change of affiliation (5.33%)’ started to increase. At the advanced level, the range of meanings increased to 31 types. The respective meanings were found to expand to containing considerably abstract information such as ‘shift of belief, value, and perspective of an individual or a society’ The above can be summarized as the following; first, the development of learners’ proficiency results in the competence to use a polysemy in diverse context, second, the expansion of meaning proceeds in the direction of concrete meanings to abstract meanings. These results are contrary to prior research that claimed learners' proficiency ineffective in expanding the range of meanings.

초기 해양생물막으로부터 분리된 미생물의 특성

권개경(Kae Kyoung Kwon),이순재(Soon Jae Lee),박재현(Jae Hyun Park),이유경(Yoo Kyung Lee),조경희(Kyeung Hee Cho),이홍금(Hong Kum Lee) 한국해양환경·에너지학회 2004 한국해양환경·에너지학회 학술대회논문집 Vol.2004 No.-

Biofilm is a starting point of biofouling and biocorrosion. However there was not enough informations about the biofilm forming bacteria in marine environments. In the present study, phylogenetic position and bacterial properties thought to be concerned in biofilm formation such as cell surface hydrophobicity, attachment on surface, production of quorum sensing (QS) signal molecule etc. were investigated for 76 isolates of 3 days old biofilm. Based on the partial sequences of 16S rDNA, the isolates could be assigned to 30 known genera which have been reported as widespread in marine environment. Approximately 31% of the isolates had been reported previously as uncultured or unidentified in GenBank database. Cell surface hydrophobicity and attachment ability were usually incompatible in a same strain except two strains. Among the 39 strains producing Acyl-Homoserine Lactone (AHL), 21 strains could degrade AHL molecules. Among the isolates, high values of cell surface hydrophobicity were found in the strains belong to high GC gram positive group and attachment ability was relatively high in low GC gram positive bacteria. To the contrary, average value of EPS productivity was highest in γ-Proteobacteria These results implied that the role of bacterial strains in the process of biofilm formation is closely related to the phylogenetic position.

외부공간 요소에 따른 농촌마을의 유휴공간 계획

김은자(Kim, Eun Ja),이유경(Lee, Yoo Kyoung),임창수(Lim, Chang Su),박미정(Park, Mee Jeong),최진아(Choi, Jin Ah) 한국지역사회생활과학회 2015 한국지역사회생활과학회 학술대회 자료집 Vol.2015 No.4

학문 목적 한국어 학습자의 다중 텍스트 활용 양상 연구

장미경 ( Chang Mi-kyung ),이유경 ( Lee Yoo-kyoung ) 우리어문학회 2024 우리어문연구 Vol.78 No.-

본 연구는 학문 목적 한국어 학습자들이 한국어 읽기 수업의 과제 수행 상황에서 다중 텍스트를 활용하는 양상을 분석하였다. 다중 텍스트 활용은 학습자들이 텍스트를 이해하기 위해 관련성이 있는 여러 개의 다른 텍스트를 찾아 내용을 통합하는 활동을 의미한다. 학습자들마다 텍스트 이해 수준이 같지 않고 다중 텍스트를 활용하는 방식이 다르다는 점에서 그 구체적인 양상을 살펴보는 것은 한국어 읽기 교육 현장에 시사하는 바가 클 것이다. 이러한 목적으로 본 연구에서는 텍스트 활용 목적, 텍스트 사용 언어, 텍스트 출처, 그리고 텍스트 유형이라는 4가지 기준을 바탕으로 학습자들이 검색한 총 63개의 다중 텍스트 활용 양상을 분석하였다. 학습자들은 주제 이해를 위해 다중 텍스트를 활용하는 빈도가 가장 높았고, 학습자들의 모국어로 된 텍스트를 찾은 경우도 25%로 비교적 높게 나타났다. 또한, 사적 텍스트의 비율이 68%였으며, 텍스트 양식에 있어 단일양식 텍스트를 찾은 비율이 83%로 상당히 높게 나타났다. 이러한 분석 결과를 토대로 향후 한국어 읽기 교육 현장에서 다중 텍스트 활용의 효율성과 신뢰성을 높일 수 있는 교수 방안을 제안하였다. This study analyzed how Korean language learners for academic purposes use multiple texts when performing tasks in Korean reading classes. Multi-text utilization refers to an activity in which learners find several other related texts and integrate the content in order to understand the text. Considering that the level of text comprehension is not the same for each learner and the way they utilize multiple texts is different, examining the specific aspects will have significant implications for the field of Korean reading education. For this purpose, this study analyzed a total of 63 multiple texts searched by learners based on four criteria: purpose of text use, language used in text, text source, and text type. Learners most frequently used multiple texts to understand topics, and the number of times they found texts in their native language was relatively high at 25%. In addition, the proportion of private texts was 68%, and the proportion of single-style texts was found to be quite high at 83%. Based on these analysis results, the significance of the study can be found in that it proposes a teaching method that can increase the efficiency and reliability of the use of multiple texts in future Korean reading education fields.

자연경관형 및 역사문화형의 농촌 마을길 계획

김은자 ( Eun Ja Kim ),이유경 ( Yoo Kyoung Lee ),임창수 ( Chang Su Lim ),최진아 ( Jin Ah Choi ),김상범 ( Sang Bum Kim ),박미정 ( Mi Jung Park ) 한국농촌계획학회 2014 농촌계획 Vol.20 No.2

This study discusses developing historical trails and ecological trails in rural area. Since the leisure time and interests in environment and health have been increasing, the number of hikers who enjoy the beautiful landscape and regional culture through the exploration of natural regions has been growing. However, these various road haven`t been related to the rural village in many cases, so it is necessary to make some alternatives for revitalizing the region and improving incomes of non farm. Therefore this study suggested the applications of rural trail plan that fits for a scale of the rural village and local characteristics. This research divided forms of the rural village road into type of the natural landscape resource (Gangreung Anbandegi Village) and that of the historical culture resource (Yongin Hakil Village) according to amenity resources of objective village. The plan for village road basically made by the best of valuable resources of village unit, connected existing ``Trail`` of other departments to the village and suggested a case of plan applied to the field so as to emphasize characteristics of rural area. It should be possible to induce hikers to rural area and be suggested as a measure for improvement of village image, regional vitalization and incomes of non farm.

수변 농촌 마을의 경관 자원 우수성 평가 방안에 관한 연구 -한강 유역 수변 농촌 마을 사례적용-

이정아 ( Jung A Lee ),이유경 ( Yoo Kyoung Lee ),이상우 ( Sang Woo Lee ),전진형 ( Jin Hyung Chon ) 한국농촌계획학회 2011 농촌계획 Vol.17 No.3

The purpose of this study is to suggest a landscape resources evaluation strategy of rural waterfront villages along the river. This strategy consists of three phases: 1) an evaluation of rural amenity landscape resources, 2) an evaluation of water landscape resources, and 3) development of a positioning map based on the results of phase 1) and 2) the study result as follows. First, the evaluation method used in phase 1) was modified as a set of proposed evaluation indicators to assess development potential on rural waterfront villages. Second, to evaluate water landscape resources in rural waterfront villages, a series of evaluation index was developed including water area, diversity of water resources, biodiversity, and landscape quality. And the last, the positioning map showed relative position of waterfront villages obtained from two evaluation results: rural amenity landscape resources and water landscape resources. The study examined the proposed strategy as a possible alternative to evaluate landscape quality to 398 rural waterfront villages along the Han River. Landscape resources evaluation strategy proposed here could contribute to government officials and planners to operate systematic planning and management of rural waterfront villages.

피투피 네트워크를 활용한 서비스 품질 제어 방법 연구

김봉완(Bong Wan Kim),이유경(Yoo-Kyoung Lee) 한국통신학회 2006 한국통신학회 학술대회논문집 Vol.2006 No.7