Screening of Bioactive Materials from Freshwater Microalgae

이완석,최애란,안치용,오현철,안종석,오희목,Lee, Wan-Seok,Choi, Ae-Ran,Ahn, Chi-Yong,Oh, Hyun-Cheol,Ahn, Jong-Seog,Oh, Hee-Mock The Korean Society of Phycology 2004 ALGAE Vol.19 No.3

One hundred and fifty four micro algal strains, newly isolated from nationwide freshwaters in Korea, were screened for their anticancer, ant diabetic, and antibiotic activities. The micro algal strains were cultured with different nutritional conditions that were divided into 4 groups as follows; a normal Allen medium, nitrogen (N)-limited medium, phosphorus (P)-limited medium, and N and P-limited medium. Algal biomass was extracted with a mixture of acetone:H₂O (1:1, v:v) and the extracts were used for the screening of bioactive materials. Anticancer, ant diabetic, and antibiotic materials were screened by the methods of vaccinia Hl-related protein tyrosine phosphates (VHR DS-PTPase) inhibition, protein tyrosine phosphates 1B (PTP1B) inhibition, and paper disk. The inhibition activity of VHR DS-PTPase was observed in 18 strains, having a maximum 79% inhibition from Anabaena affinis and the inhibition activity of PTP1B was observed in 9 strains, having a maximum 97% from Sphaerocystis schroeteri. Microcystis aeruginosa incubated in an N and P-limited medium showed antibiotic activity in 8 species out of 13 pathogenic bacteria. As a whole, it seemed that the stressed condition such as N and/or P limitation increased the production of bioactive materials in micro algae.

제조체 oxadiazon의 토양 흡탈착에 미치는 유기물의 함량과 산화환원효소의 영향

이완석(Wan-Seok Lee),김장억(Jang-Eok Kim) 한국농약과학회 1998 농약과학회지 Vol.2 No.3

전국 안경원 분포에 따른 상권 분석

이완석(Wan-Seok Lee),예기훈(Ki-Hun Ye) 한국안광학회 2017 한국안광학회지 Vol.22 No.3

Purpose: We wish to present basic research on starting an optical store by analyzing market boundaries around the country. Methods: We used the commercial district information system (2016.6) of Small Enterprise & Market Authority to analyze the market through population, the number of households and optical stores and rental prices. Statistical analyses were performed with descriptive statistics and correlation analysis with SPSS 18.0 (p<0.05). Results: Total population was 1,868,395, the rental price 11,980 won, the number of optical stores 492, density 1.88 and population per establishment 3,798 in case of Jeollabuk-do Province. Total population was 2,387,812, the rental price 12,197 won, the number of optical stores 484, density 1.60 and population per establishment 5,553 in case of Gyeongsangbuk-do Province. Total population was 1,905,177, the rental price 13,369 won, the number of optical stores 2,077, density 1.26 and population per establishment 4,739 in case of Jeollanam-do Province. Total population was 2,037,780, the rental price 14,891 won, the number of optical stores 384, density 1.25 and population per establishment 5,307 in case of Chungcheongnam-do Province. Total population was 1,564,283, the rental price 14,919 won, the number of optical stores 320, density 1.05 and population per establishment 4,883 in case of Chungcheongbuk-do Province. Total population was 12,185,139, the rental price 26,074 won, the number of optical stores 2,191, density 0.97 and population per establishment 5,561 in case of Gyeonggi-do Province. Total population was 1,535,801, the rental price 15,343 won, the number of optical stores 280, density 0.96 and population per establishment 5,485 in case of Gangwon-do Province. Total population was 588,315, the rental price 12,111 won, the number of optical stores 118, density 0.85 and population per establishment 4,986 in case of Jeju Special Self-Governing Province. Total population was 3,3,319,042, the rental price 19,554 won, the number of optical stores 620, density 0.64 and population per establishment 5,353 in case of Gyeongsangnam-do Province. Conclusions: The population per one optical store established regionally means the existence of a potential consumer group but also low clinical accessibility for patients. In case of regions where optical store density is high, it may mean a risk from severe competition. It is essential to consider priorititzing toward regions where the population per business is beyond the regional average and business density is below the national average. In addition, it will be important to consider the limits of capital by sorting the regions which can manage the expense of fixed costs represented as the market price of lease.

유류사고 이후 안면도 연안 해수 및 퇴적물의 다환방향족탄화수소(PAHs) 오염에 관한 연구

이완석 ( Wan Seok Lee ),박승윤 ( Seung Yoon Park ),김평중 ( Pyoung Joong Kim ),전상백 ( Sang Baeck Jeon ),안경호 ( Kyoung Ho An ),최용석 ( Yong Seok Choi ) 한국환경과학회 2010 한국환경과학회지 Vol.19 No.12

Polycyclic aromatic hydrocarbons (PAHs) were investigated in seawater and marine sediment from Anmyundo coastal area after oil spill. The concentrations of total PAHs in surface and bottom of seawater at August were 31.1 to 142.6 ng/L and 5.9 to 50.9 ng/L in August and November, respectively. The concentrations of PAHs in sediment were 21.0 to 102.9 ng/g D.W. and 32.3 to 57.4 ng/g D.W. in August and November, respectively. PAHs concentrations in seawater and sediment in August were higher than those in November about 2.5 and 1.4 times, respectively. Diagnostic ratio (PhA/AnT and FluA/Pyr) were investigated to identify source of PAHs in seawater and sediment. The PAHs in seawater originated from pyrolytic source and those in sediment originated from pyrolytic and petrogenic source. The glass, wood and coal origin was higher than petroleum origin on the combustion origin of PAHs in seawater and sediment. The seawater of Anmyundo costal area recovered from oil spill, but the sediments of that were weakly influenced by oil spill until now. Because this area is developed many fishing grounds, demanded Long Term Environmental Monitoring Program (LTEMP). The concentrations of PAHs on depth of sediments were investigated at station 8 and 10. The concentrations of PAHs were decreased with increasing depth.

A priori 알고리즘을 이용한 장애정보의 연관성 분석 및 시각화

이완석(Wan-Seok LEE),안제현(Je-hyun Ahn),류관희(Kwan-Hee yoo) 한국정보과학회 2018 한국정보과학회 학술발표논문집 Vol.2018 No.12

시각장애 정도에 따른 삶의 질에 관한 연구

이완석(Wan-Seok Lee),박상열(Sang-Yeol Park),예기훈(Ki-Hun Ye) 한국안광학회 2018 한국안광학회지 Vol.23 No.3

Purpose: Through the evaluation of the quality of life depending on the degree of visual impairment, we will sympathize with the discomfort of the visually handicapped, recognize the welfare service needed for improvement, and use it as basic materials for the study of the visually handicapped. Methods: The analysis regards to survey questions of basic Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) of Korea Institute for Health and Social Affairs (KIHASA)s status data of disabled people investigated in 2011, and utilizing SPSS win 12.0, technical statistics was conducted through cross analysis. Results: The factors with the highest total independence for daily life achievement abilities were changing posture 98.7%, controlling feces 98.4%, and brushing tooth 97.8%. The daily life achievement abilities that require partial and whole support were walking 11.7%, eating 9.6% and dressing 8.5%. The factors with the highest rate of total independence among instrumental daily life achievement ability were taking medicine 89.5%, using telephone 84.1%, and laundry 83.12% and the instrumental daily life achievement abilities which require partial and whole support were using the public transport 23.0%, preparing meals 21.0% and shopping 20.4%. Conclusions: Guarantee of transfer rights which is an important ability of achievement for participating in various social activities is the most pressing procedure, especially support for people with severe visual impairment and mild impairment should be customized according to the level of their independence, a basic research on the registration rate of the visually impaired people should be carried out and the development of the system for each level should be actualized.

시각장애인의 취업에 대한 실태 조사 연구

이완석(Wan-Seok Lee),예기훈(Ki-Hun Ye) 한국안광학회 2019 한국안광학회지 Vol.24 No.1

Purpose: This study is intended to provide preliminary data for developing better ways to support job seeking activities of individuals with blindness or visual impairments, by focusing on the general traits of individuals with visual impairments and their current employment status. Methods: Using data from a survey on the employment status of individuals with disabilities, conducted by the Korea Institute for Health and Social Affairs (KIHASA) in 2011, we conducted a comparative analysis on the employment status and unemployment insurance status of individuals with blindness or visual impairments and those with other functional physical disabilities, including physical disability, brain lesions, hearing impairment, language disorder, and facial nerve disorders. Results: Among individuals with blindness or visual impairments, 70.3% and 29.7% of males and females were employed, respectively. Further, these employed females with blindness or visual impairments comprised a smaller proportion of the Korean population than did females with disabilities aged 15 years and above (41.6%). The employment rate for individuals with visual impairments was 3.1%, 9.6%, and 76.5% for Level 4, 5, and 6, respectively. The employment rate for individuals with Level 6 visual impairments was significantly higher than that for individuals with any other types of disabilities. However, they were the least protected (21.2%) by the unemployment insurance. Finally, 83.7% of individuals with blindness or visual impairments worked at companies with less than 100 employees and 3.4% of them were homeworkers. Conclusions: Individuals with blindness or visual impairments inevitably experience difficulties with career choice owing to their lack of mobility and because most jobs require spatial skills that are based on visual abilities. Such factors impose substantial limitations on their career options as compared to individuals with other disabilities. Especially, female individuals with disabilities experience more discrimination during career choice than do individuals without disabilities and male individuals with disabilities. Therefore, constant efforts are required to implement welfare policies to help relieve the anxieties of individuals with blindness or visual impairments pertaining to the deprivation of wage due to unemployment or the failure of acquiring employment.

전국 안경원 및 안경사 현황을 통한 인력수급에 관한 연구

이완석(Wan-Seok Lee),예기훈(Ki-Hun Ye) 한국안광학회 2017 한국안광학회지 Vol.22 No.4

Purpose: The study can be used as basic material for optical stores and opticians by analyzing the supply and demand of optical stores throughout the nation. Methods: All ophthalmic optics data were collected from in the Korean Council for University Education, College Entrance Information Portal of the Korean Council for University College Education and the Korea Health Personnel Licensing Examination Institute. All data on establishers and optometrists were analysed with using resources from the Korean Optometric Association. Results: There were 17,059 optometrists in 2016, meaning about a ratio of one per 3,020 people. The number of establishers slightly decreased from 7,414 in 2013 to 7,223 in 2014 but increased slightly from 7,958 in 2015 to 8,209 in 2016. Generally, the number of optical stores is likely to increase, reflective of the 10.72% rate of increase since in 2013. As for the number of nationwide optometrist employees, the number of optometrists employees sharply increased every year from 5,233 in 2013 to 5,497 in 2014, 6,650 in 2015, and 7,223 in 2016. The number of unemployed optometrist licencees (in the industry) increased slightly from 1,279 in 2013 to 1,265 in 2014, and 1,413 in 2015. As of 2013, a study showed that 1,627 optometrists are either in another industry or unemployed (increase of 27.20%). Conclusions: For a substantive approach of the actual number of optometrists who can be supplied strengthening the association enrollment rate and managing unemployed licensed optometrists as potential suppliers will be very important. Especially, there should be a refined working environment and rational compensation system for part-time employees in order to prevent career interruptions for female optometrists. Furthermore, it should be recognized that examination and ophthalmic dispensing costs are a professional part of the national health and therefore should be materialized as fixed costs. In order to establish a work environment where optometrists are treated like respected eye health professionals, a system should be established within the overall medical framework.

주변압기 부분방전 진단방안 실증 사례연구

이완석(Wan-Seok Lee),김경오(Gyeong-O Kim),장동환(Dong-Hwan Jang),김대일(Dae-Il Kim) 대한전기학회 2023 대한전기학회 학술대회 논문집 Vol.2023 No.7

주변압기 부분방전 진단방안 실증 사례연구

이완석(Wan-Seok Lee),김경오(Gyeong-O Kim),장동환(Dong-Hwan Jang),김대일(Dae-Il Kim) 대한전기학회 2023 대한전기학회 학술대회 논문집 Vol.2023 No.7