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흉막액 감별에 있어서 C-반응성단백과 혈관내피성장인자의 유용성
김상하 ( Kim Sang Ha ),이원연 ( Lee Won Yeon ),박주영 ( Park Ju Yeong ),박현숙 ( Park Hyeon Sug ),한혜경 ( Han Hye Gyeong ),주헌수 ( Ju Heon Su ),홍태원 ( Hong Tae Won ),이낙원 ( Lee Nag Won ),신계철 ( Sin Gye Cheol ),용석중 ( Yon 대한결핵 및 호흡기학회 2003 Tuberculosis and Respiratory Diseases Vol.55 No.5
이원식,김정주,정순희,조미연,용석중,류정선,송창호,김도훈,신계철,송광선 대한내과학회 1996 대한내과학회지 Vol.50 No.4
The leiomyosarcoma is uncommon tumor that consist of 3-7% of all sarcoma incidence and commonly arised from retroperitoneum and mesentery. But since the first description of mediastinal leiomyosarcoma by Herlitzka in 1958, a few cases have been reported in the world literature. Mediastinal leiomyosarcoma may originate from superior vena cava, pulmonary artery, small vessels of alveoli, esophagus and cardiac muscle. The clinical features are dependent upon tumor volume, rate of growth, vascular involvement and thrombosis but the main factor is the location. The recomendations regarding appropriate therapy have not been established but treatment of choice among surgery, chemotherapy, and radiation therapy is surgical excision. Usually death from a mediastinal leiomyosarcoma occurs as a consequence of regional extension and metastasis. We report the case of anterior medistinal leiomyosarcoma conformed by histologic examination and immunohistochemical staining of biopsy specimen along with a review of literature.
Theophylline(Etheophyl(R))에 의한 약물 유발성 간염 1 예
이동기,김태헌,권상옥,박용순,김태헌,백순구,임대욱,서정인,박학천,조미연,신계철,리원연,용석중 대한간학회 2001 Clinical and Molecular Hepatology(대한간학회지) Vol.7 No.2
Theophylline has been widely used in the treatment of asthma and chronic obstructive lung disease. To date, there have been very few reports on hepatotoxicity due to theophylline. We diagnosed, through biochemical testing and a liver biopsy, a case of acute cholestatic hepatitis developed after oral consumption of theophylline. A 43 year-old man was admitted to the department of internal medicine due to jaundice and pruritus which developed after ten days administration of oral theophylline (Etheophyl). Liver function tests showed elevated serum bilirubin at 13.2 mg/dL with AST and ALT of 71 U/L and 194 U/L. Alkaline phosphatase and γ - GTP were also elevated at 175 U/L and 301 U/L. There was no evidence of viral or autoimmune hepatitis in laboratory tests. The patients symptoms and liver function tests were improved after conservative treatment. After 9 months oral theophylline was readministered for the control of relapsed asthma. Then, jaundice and pruritus again developed again. A liver biopsy showed a fw lymphocytes and eosinophilic inflammatory cell infiltration in portal tract and cholestasis in the lobule. Drug - induced hepatitis was diagnosed with a typical clinical course, the exclusion of all possible causes of acute hepatic dysfunction,' and a positive response to accidental readministration of drug. We report this case with a review of the literature.(Korean J Hepatol 2001;7:213-215)