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리원연 ( Won Yeon Lee ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.4
Interstitial lung disease (ILD) is a group of diseases characterized by pulmonary interstitial inflammation. Finally the inflammation results in pulmonary fibrosis and impairment of oxygen transportation. The causes of idiopathic interstitial pneumonia (IIP) are unknown. Diagnosis of IIP is not easy, especially distinguising between nonspecific interstitial pneumonia and usual interstitial pneumonia (UIP). First line treatments of IIP include corticosteroids and immune modulators, which have limited effect. Currently, several drugs are being researched to prevent and treat fibrosis. Newer drugs that may useful to treat pulmonary fibrosis include endothelin receptor antagonist, recombinant soluble TNF receptor antagonist, and cotrimoxazole. The causes of IIP are largely unknown, treatment is not specific, and prognosis is poor. Recent studies are underway to investigate the pathogenesis and treatment of IIP and pulmonary fibrosis. As the pathogenesis of IIP is elucidated, better treatments will emerge.
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리원연 ( Won Yeon Lee ) 대한결핵 및 호흡기학회 2011 Tuberculosis and Respiratory Diseases Vol.71 No.5
Occupational lung disease (OLD) is a group of lung diseases caused and/or aggravated by organic and inorganic inhaled dust, fumes, and mist. OLD can develop under various occupational situations. Therefore, occupational history should be considered when evaluating respiratory symptoms. Once OLD is developed, it may not be treated and may even progress after exposure to the causative agents has stopped. The best ways to treat OLD are prevention and early detection by controlling the working environment and conducting regular surveillance of workers. Common OLDs in Korea are coal worker`s pneumoconiosis, asbestos-related diseases, and occupational asthma. Recent aspects of these common OLDs in Korea will be described based on recently published studies.
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리원연 ( Won Yeon Lee ) 대한내과학회 2011 대한내과학회지 Vol.80 No.2
Critically ill patients requiring treatment in intensive care unit (ICU) are increasing recently. The patients treating in intensive care unit have various catheter, device, antibiotics treatment, and decreased immunity, and are prone to get complications from those. Some complications are clinically insignificant, but some complications may be fatal. The serious complications are including ventilator associated pneumonia that is one type of hospital acquired pneumonia, venous thromboembolism that is a major risk factor of pulmonary embolism, and stress related ulcer that make clinically significant gastrointestinal bleeding. Those complications prolong ICU stay period, increase morbidity and mortality, and cost. Therefore we should try to decrease incidence of those complications. The methods to decrease the complications in ICU are including education of facility staffs including physicians, nurses, students, and other staffs, and daily formal routine evaluation of patients in ICU. (Korean J Med 2011;80: 152-157)
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