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오연상,Oh, Yeon-Sahng 한국정신신체의학회 1995 정신신체의학 Vol.3 No.2
Obesity is a major nutritional problem in the developed countries. The prevalence of obesity may range from 10 to 50 per rent or mort of adult population and it may be increasing tendency. Many efforts have been made to understand the pathogenesis of obesity, but except a few metabolic obesities in the most of obese patients, the mechanisms are not understood. The treatment modalities of obesity, ranging from dietary and pubilc health intervention through the pharmacological and surgical therapy, have been developed and tested. In the obese patients mortalities and mobilities are significantly increased than non obese subjects due to hypertension, diabetics, and other problems. There are four possible mechanisms by which energy balance might be altered to enhance metabolic efficiency. futile metabolic pathway, alteration of protein rum over, alteration in sodium-potassium ATPase and alteration in uncoupled oxidation in brown adipose tissue are considered as possible mechanisms. Low calory and very low calory diets are recommended as a dietary program. Several pharmacological agent such as benzphetamine, fenfluramine, mazindol and fluoxetin are currently popular drugs for the treatment of obesity.
오연상,O, Yeon-Sang 사단법인 한국당뇨협회 2006 당뇨 Vol.200 No.-
지방간이라고 하면 으례 술 때문이라고 생각하기 쉽지만, 술을 거의 마시지 않는 사람이라하더라도 비만이나 당뇨병, 고지혈증 등과 같은 원인에 의해서 2차적으로 발생하는 지방간 질환도 있는데 이것을 의학적으로는 '비알코올성 지방간질환'이라고 부른다.