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구강 편평상피세포암종 세포주에서 Tumor Necrosis Factor-α와 Interleukin-6의 mRNA 발현에 관한 연구
안진수,김경욱,이재훈,Ahn, Jin-Su,Kim, Kyung-Wook,Lee, Jae-Hoon 대한구강악안면외과학회 2001 대한구강악안면외과학회지 Vol.27 No.6
The purpose of this study was to examine the mRNA levels of TNF-${\alpha}$ and IL-6 in the cell lines of normal oral keratocyte and oral squamous cell carcinoma. Total RNA was extracted from these cell lines, observed under UV light, developed by radiographic films of PCR products via reverse transcriptase polymerase chain reaction(RT-PCR) amplication, and measured with densitometer. Each mRNA level of these cell lines divided by ${\beta}$-actin mRNA level was compared to that of normal control group. The results were as follows: 1. Higher mRNA expression of TNF-${\alpha}$ than IL-6 in the normal oral epithelial cell line. 2. In general, expression of mRNA of IL-6 appeared 3-4 times more in tumor cell lines than in control group. 3. mRNA expression of TNF-${\alpha}$ showed variable expression in tumor cell lines, unlike normal cell line. 4. There are no special connections between differentiation of oral cancer cell lines and mRNA expression of TNF-${\alpha}$ and IL-6. From the above results, expression of mRNA of IL-6 in the cell lines of squamous cell carcinoma used in this study has higher than the normal oral epithelial cell line, but there are no relationship between the differentiation of oral cancer cell lines and the expression of mRNA of TNF-${\alpha}$ and IL-6.
안진수(Jin-Su Ahn),정원지(Won-Jee Chung) 한국생산제조학회 2011 한국생산제조학회지 Vol.20 No.6
This paper presents the study on orientations interpolation of 6-axis articulated robot using quaternion. In this paper, we propose a control algorithm between given two orientations of 6-axis articulated robot by using a quaternion with spherical linear interpolation. In order to study the quaternion interpolation, We created Inverse kinematics program and Interpolation program using LabVIEW<SUP>®</SUP>. The rotation angle of each axis were calculated using both euler orientations interpolation program and quaternion orientations interpolation program. The proposed control algorithm is shown to be effective in terms of motor angles and torques when compared to a conventional Euler angle interpolation, by using both LabVIEW<SUP>®</SUP> and RecurDyn<SUP>®</SUP>.
안진수(Jin-Su Ahn),정원지(Won-Jee Chung) 한국생산제조학회 2010 한국공작기계학회 추계학술대회논문집 Vol.2010 No.-
This paper presents the study on 6-Axis Articulated Robot Using using a quaternion Interpolation. In this paper, we propose a control algorithm between given two orientations of 6-Axis Articulated robot by using a quaternion with spherical linear interpolation. In order to study the Quaternion Interpolation, We created Inverse kinematics program and Interpolation program using LabVIEW<SUP>®</SUP>. The rotation angle of each axis were calculated using the euler interpolation program and quaternion Interpolation program. The proposed control algorithm is shown to be effective in terms of motor angles and torques when compared to a conventional Euler angle interpolation, by using both LabView<SUP>®</SUP> and RecurDyn<SUP>®</SUP>.
u-hospital을 위한 원격지 주사 시스템의 구현에 관한 연구
임수영(Su-Young Lim),허정일(Jung-Il Heo),서정호(Jung-Ho Seo),안진수(Jin-Soo Ahan),김우식(Woo-Shik Kim) 대한전자공학회 2007 대한전자공학회 학술대회 Vol.2007 No.7
A remote injection system for u-Hospital is used for a system in which can be made in a remote server to give an injection of Ringer's solution in very accurately at an hospital in any place where the Internet network or the LAN(Local Area Network) is set up. TCP/IP communication is used from sever to client in order that the server(or webserver) controls the injection module. The microcontroller is used for the control of syringe module. A Lead screw stepping motor is used here in order to inject the medicine contained the syringe connected to the rubber tube of the Ringer very correctly. I adopted the object-oriented programming paradigm in all the implementation and design processes. In the experiment performed, the implementation turned out to meet all the requirements needed for remote injection.
난소 절제술을 시행한 쥐와 정상 쥐에서 합성 골 재료의 이식 후 신생 골 생성 비교
이종원,안진수,안재석,류재준,Lee, Jong-Won,Ahn, Jin-Su,Ahn, Jae-Seok,Ryu, Jae-Jun 대한치과보철학회 2008 대한치과보철학회지 Vol.46 No.4
연구목적: 난소 절제술을 시행하여 골다공증을 재연한 쥐의 두개 결함부에 골 이식시 정상 쥐와 어떠한 골 재생 능력 차이를 보이는지 비교하고자 한다. 연구재료 및 방법: 20마리의 쥐를 2 그룹으로 각 10마리씩 나눈다. 그 중 10마리만 난소 절제술을 시행하고 7주 후 20마리 모두 두개골에 8 mm 직경의 임계 크기의 결함을 형성한 후 $OSTEON^{TM}$을 이식한다. 그 후 4주 후 모두 희생하여 조직학적 조각을 형성하여 방사선학적 및 조직형태학적 분석을 시행한다. 결과: Ovariectomy & $OSTEON^{TM}$군과 Non-Ovariectomy & $OSTEON^{TM}$군과의 신생골 형성 넓이의 효과 검증 결과, Ovariectomy & $OSTEON^{TM}$군은 평균 넓이는 19660.93 ${\pm}$ 17207.68 ${\mu}m$으로 Non-Ovariectomy & $OSTEON^{TM}$군의 69793.57 ${\pm}$ 33227.17 ${\mu}m$에 비해 적어진 것으로 나타났으며, 이러한 차이는 통계적으로도 유의한 것으로 나타났다 (t = -4.237, P < .01). 따라서 Ovariectomy & $OSTEON^{TM}$군의 new bone formation 넓이가 Non-Ovariectomy & $OSTEON^{TM}$군에 비해 작아진 것을 알 수 있다. Ovariectomy & $OSTEON^{TM}$ 군과 Non-Ovariectomy & $OSTEON^{TM}$ 군과의 알칼리 포스파타아제의 효과 검증 결과, Ovariectomy & $OSTEON^{TM}$군은 ALP는 평균 163.90 ${\pm}$ 61.44 IU/L으로 Non-Ovariectomy & $OSTEON^{TM}$군의 58.40 ${\pm}$ 18.30 IU/L에 비해 크게 높아진 것으로 나타났으며, 이러한 차이는 통계적으로도 유의한 것으로 나타났다 (t = 5.204, P < .001). 따라서 Ovariectomy & $OSTEON^{TM}$군의 ALP 수치가 Non-Ovariectomy & $OSTEON^{TM}$군 ALP 수치보다 높아진 것을 알 수 있다. 결론: 본 실험을 통해 골다공증이 유발되면 골 재생능력이 감소한다는 것을 결론지을 수 있다. Purpose of study: To compare on bone formation between ovariectomized rats and normal rats after graft of alloplastic bone material. Material and methods: Twenty female rats were used in this study. They were divided into two groups by each ten rats. One group was ovariectomized and grafted alloplastic bone material. Other group was non-ovariectomized and grafted alloplastic bone material. After a healing time of 4 weeks, the animals were sacrificed and decalcified preparations were routinely processed for histologic evaluations. Results: Ovariectomy group was significantly lesser bone formation compared with non-ovariectomy group. Conclusions: Ovariectomy acts as a negative factor in new bone formation.