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      • SCOPUSKCI등재

        태아(胎兒) 의 현사구체경화증(賢絲球體硬化症)

        신희영 대한신장학회 1987 Kidney Research and Clinical Practice Vol.6 No.2

        Since Herxheimer (1909) first described the presence of glomerulosclerosis in the kidney of newborn, there had been only a few reports on the glomerulosclerosis seen among fetuses and neonates. We are still not aware of the true incidence of glomerulosclerosis in fetuses, particularly among different age groups of the fetuses. The authors conducted a study to elucidate the fre- quency and possible cause of this condition. A total of 307 normal fetal kidneys were selected from autopsy specimens ranging in gestational age from 15 to 41 weeks. A large section covering entire midlon- gitudinal surface of each kidney was made for the microscopic examination. The glomerulosclerosis was not seen in fetuses before the gestational age of 26 weeks. It was first seen in fetuses in the age range of 26-27 weeks and then tended to increase steadily with the aging of the fetus, approaching near 50% by term. The sclerotic glomerui located mostly in the juxtamedullary portion of the cortex and was generally larger than the remaining uninvolved ones. The sclerotic glomeruli were characterized by thickening of the parietal layer of the Bowmans capsule and were associated with segmental and global sclerosis of the glomerular capillary tufts. Periglomerular lamellated fibrosis was also commonly seen among these glomeruli.

      • 한국 사회복지체제의 개혁모델에 대한 논의와 탐색 : 거버넌스이론을 중심으로 Governance Approach

        신희영 경주대학교 2004 論文集 Vol.17 No.-

        This paper attempts to explore the direction of Korean Welfare System reform. Productive Welfare Policy-a New Welfare Model- is described as bold attempt to expand and guarantee the fundamental democratic and social rights of all citizen. It is generated to manage the contradictions of system integration imperatives and social integration imperatives after the economic crisis 1997. But It is not sufficient for improving the security of social life. It is necessary to overcome the nature(neoliberalism) and structural constraints of Productive Welfare for democracy's consolidation and survival. Governance theory helps to construct the model of welfare system. Governance is defined as the reflexive self-organization of independent actors involved in complex relations of reciprocal interdependence, with such self-organization being based on continuing dialogue and resource-sharing to develop mutually beneficial joint projects and to manage the contradiction and dilemmas inevitably involved in such situation.

      • KCI등재

        건강한 젊은 성인에서 Aldehyde Dehydrogenase 2 유전자형에 따라서 알코올이 주간의 졸음, 정신운동성 수행 및 주관적 반응에 미치는 영향의 비교: 이중맹검 위약대조 교차연구

        신희영,신일선 대한정신약물학회 2006 대한정신약물학회지 Vol.17 No.1

        Objective : This study aimed to investigate the effects of alcohol on daytime sleepiness, psychomotor performance, and subjective response in healthy young men with different ALDH2 genotypes. Methods : A total of 24 males, half with the active ALDH2*1/*1 and the rest with inactive the ALDH2*1/*2, were selected through genotyping. In a double-blind, placebo-controlled crossover design, each subject consumed either a 0.5 g/kg dose of alcohol or placebo in the morning on two separate occasions, a week apart. Multiple Sleep Latency Test, a battery of psychomotor tests (Critical Flicker Fusion Threshold, Choice Reaction Time, Compensatory Tracking Task, Digit Symbol Substitution), questionnaire for subjective response and modified Epworth Sleepiness Scale were administered. Results : Daytime sleep latency was significantly decreased after alcohol intake in the morning compared to placebo, and the decrease was much greater in subjects with ALDH2*1/*2 than in subjects with ALDH2*1/*1. Psychomotor function was significantly impaired after alcohol intake in the morning compared to placebo, in subjects with ALDH2*1/*2. Subjective response was significantly negative or intense after alcohol intake in the morning, compared to placebo, in subjects with ALDH2*1/*2. Subjective daytime sleepiness was significantly increased after alcohol intake compared to placebo, in subjects with ALDH2*1/*2. Conclusions : These results supported that ALDH2 polymorphism might be one of important factors in determining the effects of alcohol on the various psychobehavioural functions as well as on patterns of alcohol use.

      • 가족복지와 국가의 역할

        신희영 경주대학교 1999 論文集 Vol.12 No.1

        This study aims at exploring Family Welfare Regime to solve the problem of family structure and functions in Korea. Family allowance, family assistance program, and family planing services are underdeveloped in Korea. Families are exposed to economic cycle and economic crisis without the economical and social security arrangements. This results in the trends of disorganizing families. Family policy treat family as the whole and is to regenerate the functions of family. There are the approaches to family welfare. N대-conservative approach transfers the burdens of welfare state to family, community, and the market through restoring the traditional norms; the responsibility ethics of households, work ethics, civic morals. According to Statist approach, the state can delivery effectively the social welfare services by decentralization and de-bureaucratization and administrative reforms. But both the approaches have the inherent limits. This study suggests that the integrative social forces of solidarity must control the market and state power toward a highly innovation combination of the power and intelligent self-restraint.

      • 산업정책부문에서의 정부-기업관계의 유형 : 산업정책결정에 대한 구조적 접근 Structural Approach to Industrial Policymaking

        申熙永 경주대학교 1994 論文集 Vol.6 No.-

        This sdudy aims at analyzing opportunity stuctures of policy making in industrial policy sector. This structures that refer to the network of the state and socety in industrial policy sector make poltical actors have access to policy bodies selectively and differentialy. Thus, whoses interests put in state policy depend upon patterns of industrial policy network. For this purpose, this study analyzes this structures through the distinctive feature of state structures and he degree that social interests have the acquisition of social status as strategic actor and organize thier resources. this analysis help to understand the mode that the structure have constraintes to the action in policy process. According to structural approach, this study analyses this structure. This approach different from pluarlism problematics help to analyze the asymmetry power-relationship among groups in political process.

      • KCI등재

        정신분열병 및 기타 정신증적 장애 환자의 외래 유지치료에서 Olanzapine의 효과

        신희영,김성완,김재현,정영철,정인원,지익성,윤보현,윤진상 대한정신약물학회 2006 대한정신약물학회지 Vol.17 No.4

        Objectives:This open multicenter trial examined the effects of olanzapine on profiles of efficacy, safety, and subjective quality of life (QoL) in the maintenance treatment of stable outpatients with schizophrenia or other psychotic disorders. Methods: A total of 47patients who had completed acute inpatient treatment with olanzapine were recruited from six centers. Information on sociodemographic and clinical characteristics was collected. A variety of measures for efficacy, safety, and QoL were administered at the time of discharge (baseline) and after 12 weeks of maintenance treatment (endpoint). Results: Twenty (43%) patients discontinued olanzapine treatment for various reasons. Twenty-seven patients (57%) completed the study, and in this group, there was a significant additional reduction in overall psychotic symptoms, including negative symptoms. Olanzapine was generally well-tolerated, although substantial weight gain was observed. However, QoL was not improved further during the maintenance treatment. Conclusions: Olanzapine was generally effective and well-tolerated in the maintenance treatment of stable outpatients with schizophrenia and other psychotic disorders.

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