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- 저자 : 배성창 ( Sung Chang Bae ) (검색결과 3 건)
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증례 : 소화기 ; 생검으로 진단된 간의 혈관근지방종 1예
장성일 ( Sung Ill Jang ),박형순 ( Hyung Soon Park ),유정환 ( Jung Whan Yu ),배성창 ( Sung Chang Bae ),정재준 ( Jae Jun Chung ),백용한 ( Yong Han Paik ),김자경 ( Ja Kyung Kim ) 대한내과학회 2010 대한내과학회지 Vol.79 No.3
저자들은 건강검진상 우연히 발견된 간내종물에 대해 생검을 시행하여 간의 혈관근지방종으로 진단된 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Angiomyolipoma occurs most commonly in the kidneys; the liver is the second most frequent site of involvement. Hepatic angiomyolipoma is a rare, benign, mesenchymal neoplasm, composed mainly of blood vessels, smooth muscle cells, fat, and myelocomponents. Radiologic findings are non-specific because the various elements of these neoplasms vary in their proportion and distribution within the tumor. Thus, data obtained by imaging technologies such as computed tomography, ultrasonography, or magnetic resonance imaging tend to be merely suggestive; definitive diagnosis usually requires histologic confirmation. We report here a case of angiomyolipoma in an incidental tumor of the liver of a 53-year-old female. Tissue was removed from the tumor by ultrasonography-guided gun biopsy and subjected to immunohistochemical analysis. Data showed that tumor cells were positive for HMB-45 and SMA, but negative for cytokeratin, anti-hepatocyte antigen, and α-fetoprotein. The patient did not receive any treatment and is being followed up. (Korean J Med 79:295-300, 2010)
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자가 면역성 갑상선염 환자에서 발생한 쇼그렌 증후군과 원위 세뇨관 산증 1예
안혜림 ( Hye Rim An ),배성창 ( Sung Chang Bae ),이기병 ( Ki Byung Lee ),이용규 ( Yong Kyu Lee ),김좌경 ( Jwa Kyung Kim ),박형천 ( Hyeong Cheon Park ),하성규 ( Sung Kyu Ha ),이정은 ( Jung Eun Lee ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.1
A 52-year old woman, who had hypothyroidism associated with autoimmune thyroiditis for 5 years, was hospitalized for tingling sensation and muscle weakness of both lower extremities. Her initial laboratory findings showed severe hypokalemia, metabolic acidosis, and high titer of thyroid autoimmune antibodies. She was diagnosed of distal renal tubular acidosis by bicarbonate loading test (FEHCO3-<3.0%) and renal calcifications on pre-enhanced CT scan. Since she had other symptoms of xerostomia and xerophthalmia, primary Sjogren`s syndrome was diagnosed by Schirmer test, salivary scan, and serologic findings. She was treated with potassium citrate, potassium chloride, and hydroxychlorquine. Four months later, she has remained well with those treatments. There were only a few case reports about distal renal tubular acidosis associated with Sjogren`s syndrome and autoimmune thyroiditis. In Korea, there has not been any report of such cases. Therefore, we report a case of distal renal tubular acidosis and Sjogren`s syndrome in a patient with autoimmune thyroiditis.
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노인에서 혈청 Cystatin C 농도를 이용한 반코마이신 투여용량 평가
진성준,배성창,김혜원,김혜경,나은주,안보숙,최준용,김창오,김준명,송영구 대한감염학회 2009 감염과 화학요법 Vol.41 No.4
Background : It has been suggested that the glomerular filtration rate can be predicted on the basis of serum cystatin C concentration. The aim of this study was to investigate the clinical utility of serum cystatin C as a marker of renal function and to evaluate the effect of an initial dose of vancomycin using serum cystatin C concentration in elderly patients. Materials and Methods : Data was collected from July 2006 to September 2008. The subjects were elderly patients (≥60-years-of-age; n=number of patients) who had been treated with vancomycin. Serum concentrations of parameters including vancomycin, creatinine, and cystatin C were measured. Correlations between measured vancomycin concentrations and predicted vancomycin concentrations based on serum cystatin C or serum creatinine were compared, and the initial dose setting of vancomycin on the basis of serum cystatin C concentration was evaluated. Results : Serum cystatin C was a good marker of renal function in comparison with serum creatinine for various doses of vancomycin in the elderly subject. In subpopulation (n=88) with normal serum cystatin C level (≤1.2 mg/L) who were treated with routine adult vancomycin dose (1g q 12 hours), vancomycin concentration was within the therapeutic range (5-15 mg/L) in 68 patients (77.3%), and was <20 mg/L in 77 of the 88 patients (88.5%). Conclusions : Predictive prowess of serum vancomycin concentrations on the basis of the serum cystatin C concentration could be better than that based on the serum creatinine concentration in elderly patients.
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