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      • KCI등재

        탈회동결건조골이 수직골 형성에 미치는 영향

        박주희,권영혁,박준봉,정종혁,신승일,허익,Park, Ju-Hee,Kwon, Young-Hyuk,Park, Joon-Bong,Chung, Jong-Hyuk,Shin, Seung-Il,Herr, Yeek 대한치주과학회 2008 Journal of Periodontal & Implant Science Vol.38 No.1

        Purpose: The purpose of this study was to evaluate exophytically vertical bone formation in the mandibular premolar area of beagle dogs by the concept of guided bone regeneration with a titanium reinforced e-PTFE membrane combined with human demineralized freeze-dried bone. Materials and Methods: Four one-year old beagle dogs were divided into control and experimental group. All mandibular premolars were extracted and surgical vertical defects of 5 mm in height were created in the extracted sockets. At 8 weeks after the extraction, TR e-PTFE membrane sized with 8 mm in length, 5 mm in width, and 4 mm in height was placed on the decorticated mandible, fixed with metal pins and covered with full-thickness flap and assigned as control group. In experimental group, decorticated mandibule was treated with TR e-PTFE membrane and human demineralized freeze-dried bone. The animals were sacrificed at 16 weeks after the regenerative surgery, and new bone formation was assessed by histomorphometric as well as statistical analysis. Results: Average of new bone formation was 38% in the control group, whereas was 25% in the experimental group (p<0.05). Average of connective tissue formation was 42% in the experimental group, whereas was 30% in the control group (p<0.05). The lamellar bone formation with haversian canals was observed in the both groups. In the experimental group, the particles of human demineralized freeze-dried bone were observed after 16 weeks and complete resorption of graft was not observed. Conclusion: On the basis of these findings, we conclude that titanium reinforced e-PTFE membrane may be used alone for vertical guided bone regeneration, but demineralized freeze-dried bone has no additional effect on vertical guided bone regeneration.

      • KCI등재

        중년기 기혼남녀의 가족생활 스트레스, 가족가치관이 결혼안정성에 미치는 영향

        박주희,Park, Ju-Hee 한국가족자원경영학회 2018 가족자원경영과 정책 Vol.22 No.4

        The purpose of this study was to explore the effects of family life stress and family values on marital stability among middle-aged couples. The subjects included a total of 302 men and women aged 45-64 who had been married for more than 20 years and were living in Seoul. The collected data were statistically analyzed with the SPSS 21.0 Package. First, Cronbach's alpha was calculated to measure the reliability of the scale that assessed the variables of the research model. Then, mean and standard deviation were calculated to determine the degrees of family life stress, family values, and marital stability among the subjects. Finally, a hierarchical multiple regression analysis was performed to identify factors that affected the subjects' marital stability. The results revealed that the level of family life stress in middle-aged married men and women was slightly higher than the mean value. Of all the sub-scales of family life stress, the subjects were found to experience the most stress from factors related to financial pressure, followed by family relationships, a sense of loss within a family, and work-family compatibility. Therefore, financial problems were one of the critical stressors for middle-aged married couples. Also, for this demographic, the levels of family values and marital stability were higher than the medians. The factors affecting marital stability in middle-aged couples were identified to be family relationship stress, financial stress, subjective economic status, family values, stress related to work-familycompatibility,religion,andage.Thedegreeofmaritalstabilitywashigherinmiddle-agedcouplesa stheirstresslevelsfromfamilyrelationshipsandfinancialproblemswerelower.Moreover,thehigherthes ubjectiveeconomicstatusandthemoretraditionalthefamilyvalues,thehigherthedegreeofmaritalstabili ty.Finally,marriedcoupleswhowerereligioushadalowerlevelofstressfromwork-family compatibility, and the younger the couples, the higher the degree of marital stability.

      • KCI등재

        제 1상 임상시험에서 멈춤 규칙을 이용한 수정된 최대허용용량 추정법

        박주희,김동재,Park, Ju Hee,Kim, Dongjae 한국데이터정보과학회 2012 한국데이터정보과학회지 Vol.23 No.6

        제 1상 임상시험의 주목적은 신약 후보 물질의 독성을 평가하여 부작용 및 안전하게 투여할 수 있는 약물의 적정한 용량인 최대허용용량의 추정이다. 기존에 최대허용용량을 추정하는 방법에는 표준방법 (Storer, 1989; Korn 등, 1994) 그리고 NM방법 (Lee와 Kim, 2012) 등이 있다. 본 연구에서는 많은 피험자들이 낮은 용량에 많이 할당되는 점을 보완하고 기존의 최대허용용량 추정법보다 적은 수의 피험자로 실험하기 위해서 기존 최대허용용량 추정법을 수정한 멈춤 규칙을 적용시킨 추정법을 제안하였다. 기존의 방법들과 새롭게 제시한 방법을 모의실험을 통하여 비교하였다. Phase I clinical trials are designed to identify an appropriate dose; the maximum tolerated dose, which assures safety of a new drug by evaluating the toxicity at each dose-level. The adjusted maximum tolerated dose estimation is presented by stopping rule in phase I clinical trial on this research. The suggested maximum tolerated dose estimation is compared to the standard method3 and NM method using a Monte Carlo simulation study.

      • KCI등재

        융복합 시대의 사회적 자본이 노년기 우울에 미치는 영향

        박주희,Park, Ju-Hee 한국사물인터넷학회 2021 한국사물인터넷학회 논문지 Vol.7 No.3

        본 연구의 목적은 사회적 신뢰, 네트워크, 규범, 참여 등의 융복합 시대의 사회적 자본이 노년기에 경험할 수 있는 우울에 어떠한 영향을 미치는지를 탐구하는데 있다. 본 연구의 대상은 서울시와 경기도 지역에 거주하는 65세 이상 노인 302명이다. 분석결과, 노인이 교육수준이 낮고 종교가 없으며 사회적 자본의 네트워크와 규범 수준이 낮을수록 우울이 높은 것으로 나타났다. 본 연구에서 우울에 가장 영향력 있는 변인으로 사회적 자본의 네트워크로 나타났다. 본 연구를 통해 노년기 우울을 완화하기 위해서는 우리 사회 전체의 네트워크를 활성하고 확대하는 노력이 요구된다. 노인의 네트워크 활성화를 위해 지역사회의 활동공간 확장과 다양한 융복합 컨텐츠의 프로그램 개발, 노인교육프로그램의 확대가 필요하다. The purpose of this study is to analyze the effect of social capital include networks, trust, norms, and participation on depression in the elderly in the era of convergence. The subjects of this study were 302 senior citizens aged 65 and over who are living in Seoul and Gyeonggi Province. The results are follows. Depression was more severe in the elderly with lower level of education, no religion, and lower social capital including networks and norms. In this study, social networks were found to be the most important contributor to depression. In order to alleviate depression in the elderly through this study, efforts to activate and expand the network of the entire society are required. In other words, it is necessary to expand the activity space of local community, develop programs for various convergence contents, and expand education programs for the elderly in order to vitalize the network of the elderly.

      • KCI등재

        치매 노인을 돌보는 노년기 배우자의 돌봄 부담감이 생활만족도에 미치는 영향: 사회적지지의 조절효과

        박주희,Park, Ju-Hee 한국가족자원경영학회 2021 가족자원경영과 정책 Vol.25 No.4

        The purpose of this study was to explore the effects of perceived care-related burden and social support on life satisfaction and the moderating effect of social support from elderly spouses caring for their elderly partners with dementia. The subjects were 165 spouses aged over 60 years, caring for their elderly partners afflicted with dementia, and living in Seoul and Gyeonggi Province. The analysis results are as follows: First, the quantified total care-related burden shouldered by the participant spouses was 3.76 points (SD = .57), which was slightly higher than the median value. In the case of social support, informal support was scored 2.65 (SD = .78), and formal support was scored 2.60 (SD = .77), which was lower than the median value. Life satisfaction earned a score of 3.11 points (SD = .78), which somewhat exceeded the median. Second, subjective health status, income level, burden from social activity, and informal support influenced life satisfaction. Put differently, the higher the subjective health status of a caring spouse, the higher the income level, the lower the social activity burden, the stronger the informal support, and the greater the life satisfaction. Third, the interaction terms of social activity burden and informal support were significant. Therefore, informal support had a moderating effect on the relationship between social activity burden and life satisfaction among the elderly with dementia. In other words, even though the caring spouses experienced a burden from social activities, the higher the frequency with which they accessed informal support, the lower the decrease in life satisfaction.

      • 우수논문상 (생식내분비학)

        박주희 ( Ju Hee Park ),( Seul Ki Kim ),( Jayeon Kim ),( Ji Hee Kim ),( Jae Hoon Chang ),( Byung Chul Jee ),( Seok Hyun Kim ) 대한산부인과학회 2016 대한산부인과학회 학술대회 Vol.102 No.-

        Objective: The study aimed to evaluate the feasibility and reproducibility of measuring phospholipase C zeta (PLCζ) using immunostaining in human sperm and to investigate the relationship between PLCζ immunoreactivity and DNA fragmentation and oxidation in human sperm. Methods: Semen samples were obtained from participants (n=44) and processed by the conventional swim-up method. Sperm concentration, motility, normal form by strict morphology, DNA fragmentation index assessed by terminal deoxynucleotidyl transferase dUTP nick end labeling method and immunofluorescent expression for 8-hydroxy-2’- deoxyguanosine (8-OHdG) and PLCζ were assessed. Results: When duplicate PLCζ tests were performed on two sperm samples from each of the 44 participants, similar results were obtained (74.1±9.4% vs. 75.4±9.7%). Two measurements of PLCζ were found to be highly correlated with each other (r=0.759, P<0.001). Immunoreactivity of PLCζ was not associated with donor’s age, sperm concentration, motility, and the percentage of normal form as well as DNA fragmentation index. However, immunoreactivity of PLCζ showed a significant negative relationship with 8-OHdG immunoreactivity (r=-0.404, P=0.009). Conclusion: Measurement of PLCζ by immunostaining is feasible and reproducible. Lower expression of PLCζ in human sperm may be associated with higher sperm DNA oxidation status.

      • KCI등재SCOPUS

        우연히 진단된 경계성 난관 장액성 종양

        박주희 ( Ju Hee Park ),임명철 ( Myong Cheol Lim ),김상욱 ( Sang Wook Kim ),김슬기 ( Seul Ki Kim ),유종우 ( Chong Woo Yoo ),박상윤 ( Sang Yoon Park ) 대한산부인과학회 2009 Obstetrics & Gynecology Science Vol.52 No.10

        Serous borderline tumors (SBTs) of the fallopian tube are very rare and usually diagnosed incidentally. We present a case of SBTs of left fallopian tube incidentally diagnosed during laparoscopic hysterectomy because of increasing symptomatic myoma. Preoperative abdomino-pelvic CT revealed 6 cm sized myoma in uterus but no gross lesion on both adnexa. Preoperative serum CA 125 was 18.9 U/mL. At laparoscopy a 2.0 cm sized polypoid mass protruding from the ampulla portion of the left tube was found. The contralateral fallopian tube, ovaries and uterus were unremarkable except previous known uterine myoma. Exploration of the abdomino-pelvic cavity has shown no abnormal finding. Intraoperative frozen biopsy to tubal mass suggested borderline malignancy but did not completely rule out tubal carcinoma. So, standard laparotomy staging operative procedures such as hysterectomy, bilateral salpingooophorectomy, omentectomy, lymph node dissection, and appendectomy were performed. Serous borderline tumor limited tube was confirmed in permanent pathology. In English literature, only 7 cases have been reported. And the current case is the first report in Korean as far as we know. Treatment for SBTs of fallopian tube is complete excision like borderline ovarian tumor. Recurrence was not reported with up to 6 year follow up in 7 cases.

      • KCI등재
      • KCI등재

        현대패션의 박물관 전시에 관한 연구

        박주희 ( Ju-hee Park ),함연자 ( Youn-ja Ham ) 한국디자인트렌드학회 2014 한국디자인포럼 Vol.42 No.-

        본 연구는 예술 박물관, 디자인 박물관을 포함하여 패션 박물관에서 이루어지는 패션 전시의 연구를 통해 패션이 예술로 기능하는 오늘날의 현상을 논의하고 그 의미를 밝히는데 목적을 두었다. 이를 위해 패션 박물관이 생기기 이전의 패션 전시에 대한 논의와 역사를 고찰하고, 패션 박물관 설립의 역사, 패션 박물관을 중심으로 기획되는 동시대 패션 전시의 형식별 연구 및 의미논의를 하였다. 동시대 전시의 연구범위는 박물관의 패션 전시가 활발히 일어나기 시작한 2010년을 전후하여 2009년부터 2013년까지 5년간으로 한정하였으며, 유럽과 미국, 일본을 비롯한 세계의 예술 박물관, 디자인 박물관, 패션 박물관에서 이루어지고 있는 패션 전시를 대상으로 분석하였다. 문헌연구와 사례분석을 통해 동시대 패션 전시는 주제별, 장소별 분류에 의해 디자이너 혹은 유명인을 기리는 회고전시, 패션현상의 변화에 주목한 주제전시, 국가와 도시를 이동하며 전시하는 순회전시, 자체박물관을 활용하는 패션하우스 전시로 분류하여 논의하였다. 오늘날 활발하게 진행되는 패션 전시의 의미로는 기금마련 및 관람객 유치 등에 관한 경제적 의미, 예술과 패션의 관계변화의 관점에서 파악되는 예술영역의 확대현상이 도출되었으며 이를 바탕으로 국내 패션 전시의 전망을 논의하였다. The aim of this study is to discuss today`s fashion as art by examining fashion exhibitions in museums. The study explored the history of fashion exhibitions before and after the establishment of the Fashion Museum. Through this case study, the study classifies exhibitions and discusses their significance. The review of literature and case study had been conducted so as to analyse the different types of contemporary fashion exhibitions. The study was conducted over a period of five years from 2009 to 2013, as fashion exhibitions have actively emerged approximately since the year 2010. The subjects of research were the exhibitions held in art museums, design museums and fashion museums in Europe, the United States and Japan. The study discusses retrospective exhibitions honoring historic designers and celebrities, thematic exhibitions that focus on the metamorphosis into today`s fashion, traveling exhibitions and self-museum exhibitions for fashion houses. The economic implications and the expansion of the meaning of art are discussed as the significance of fashion exhibitions. The study has also discussed the prospects for fashion exhibitions in Korea.

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