가톨릭 교회를 중심으로 한 한국에서의 자연가족계획 방법 수용 및 사용효과에 관한 연구

박신애,Park, Shin-Ae 한국지역사회간호학회 1993 지역사회간호학회지 Vol.4 No.2

The natural growth rate of the Korean population has decreased from 3.0% in 1960 to 1.0% in 1990. This was done with family planning program which was introduced by the government in 1961. The family planning program focused on birth control rather than the characteristics of the individuals and motivations of contraception. People were simply forced to use the method. Whereas, Natural Contraceptive is a method of family planning based solely on the timing of intercourse with the naturally occurring' physiological manifestation of fertilization and in fertilization during the menstrual cycle. This is the combination of self fertility awareness with periodic abstinence. Natural family .planning(NFP) programs in Korea were first started in the Chun-Chen diocese of catholic church by Bishop Thomas Stewart in 1970 In 1975, the Bishops conference launched the Korea Happy Family Movement in the Catholic Hospital Association, to promote the natural family planning. An average of 70,000 people, including adolescents, college students, unmarried and married persons, arid the clergies were trained during a six-year period (1986-1991). 61.5%(24,542 people) of those who completed 3 cycles during 6 year period (1986-1991) became autonomous users and the range was from 48.1% to 78.2%. In 1986, 22.7% of NFP individuals who drooped out of the program because of the desire for conception (23.4%), the difficulty of the method used(25.8%), and the loss of interest(22.8%). During the six-year period the unplanned pregnancy rate at the NFP was 2.9%. The range of the pregnancy rate was at 1.2-9.8%. The rate was decreased as years passed. The major reason for the failure of contraceptive was error by the individuals(61.1%). The percentage of the success of conception was 18.1% of 2.979 for achieving pregnancy. The highest percentage was 58.2% (99 users) in Kwang-Joo diocese and next was 37.1% (10 users) in Chong Joo diocese.

자연적 가족계획 방법에 대한 이론적 고찰

박신애,Park, Shin-Ae 한국지역사회간호학회 1996 지역사회간호학회지 Vol.7 No.2

This study was reviewed from 1000 articles related to family planning from 1970 to 1990 and 20 articles associated with natural family planning from 1980 until the present. The purpose of natural family planning(NFP) is to identify the time ovulation of women themselves, to have intercourse with periodic abstinence, and to deliver a healthy child. The ultimate goal of NFP is to promote the family's health. The NFP method is described as periodic abstinence of intercourse to avoid pregnancy by identifying the ovulation time in the menstration cycle. Clinical symptoms and signs of reflection underlying changes in Estrogen and Progesterone are the change of basal body temperature, the change of cervical mucus and cervix, abdominal pain and breast tenderness. The types of NFP are the calender rthythm method, basal body temperature methods, cervical mucus method, symptothermal method, cyclo-thermal method and home based ovulation test kits. Recently the cyclo-thermal method involved. It is calendar rhythm method applied to B.B.T. For the cervical mucus method, when the estrogen level in the blood concentration is increased, the mucus begins to excrete, the amount of moist mucus increases while the mucus is clear, slippery, and smooth. For 3 days, this timing can be considered contraception. Fertility is at a maximum on the day mucus appears, abstinence for 3 days is a type of contraception. Sexual intercourse on a maximum day of mucus maximizes pregnancy potential. But, the contraception depends on the practice of a perfect rule. For basal body temperature methods, at ovulation time, the temperature increases $0.2^{\circ}C-0.5^{\circ}C$. Through the review of literature a high temperature above $0.2^{\circ}C$ for 3 days indicates that the previous 6 day period was ovulation and fertilization. The Symptothermal method is used to determine the prediction of ovulation through the observation of mucus excretion, high temperature, the change of cervical mucus, low abdominal pain, vaginal discharge, and breast change. Home based ovulation test kits are cervico-vaginal fluid aspiration, test a digital electric thermometer, body fluid(blood, saliva, urine) test kits, They are on the market. However, research on the contraception method is still in progress. For pregnancy it is still too early to use home based ovulation test kits because of deficit of reliability and simplicity more research on the technology is needed. It is suggested that NFP methods be included in nursing curriculum in order to educate NFP users how to effectively use NFP methods. Furthermore, this study has implications for the dissemination of NFP methods in terms of Korean policies of family planning and the support of community welfare agences.

박테리아의 히스톤 유사 단백질에 의한 유전자 발현 조절

박신애,이정신,Park, Shinae,Lee, Jung-Shin 한국미생물학회 2018 미생물학회지 Vol.54 No.1

원핵 세포는 핵양체 결합 단백질(NAP)로 알려진 다양한 히스톤 유사 단백질을 가지고 있다. 이들은 DNA의 AT-rich 서열에 결합하여, DNA 자체를 감싸거나, 구부리거나, 떨어져 있는 DNA 가닥을 연결시키는 다리 역할을 하여, 결국에는 원핵 생물의 유전자 발현을 조절한다. NAP는 특히 전사의 억제 기능을 가지고 있기 때문에, 유전자 발현 억제에 있어서 이들의 역할과, 구체적인 메커니즘을 밝히는 것을 매우 중요한 일이다. 본 논문에서는 잘 알려져 있는 NAP인 H-NS와 HU에 대하여 정리하였고, 특히 E. coli와 Salmonella Typhimurium에서 이들의 유전자 발현에 대한 기능을 요약하였다. H-NS는 이들의 올리고머화와 필라멘트 구조 형성을 통하여 Salmonella와 같은 사람에 감염하는 병원성 세균의 독성유전자 발현을 억제할 수 있고, 이런 기능을 수행하였을 때 다른 NAP와 함께 작용할 수 있다. 최근에 H-NS는 사람에게 typhoid fever와 systemic disease를 발생시키는 독성물질인, typhoid toxin의 발현 또한 조절할 수 있음이 밝혀졌다. Salmonella에서 HU 또한 독성 유전자뿐만 아니라, 이들의 생리적 기능에 중요한 유전자들의 발현을 조절할 수 있다. 따라서, H-NS와 HU와 같은 NAP들이 원핵 생물의 독성 유전자 발현의 분자적인 메커니즘을 밝히는데 중요한 요소임을 제시한다. A prokaryotic cell has various histone-like proteins also known as nucleoid-associated proteins (NAPs). These proteins bind AT-rich sequence at DNA, which induce DNA wrapping, bending, and bridging, and subsequently regulate the gene expression in bacteria. Because NAPs function in transcriptional silencing of virulence genes, it is important to study their roles in gene silencing and specific mechanisms of these proteins. In this review, we discussed two well-known NAPs, H-NS, and HU, and summarized their roles for gene expression in Escherichia coli and Salmonella Typhimurium. Through the oligomerization and filamentation of H-NS, it represses the expression of virulence genes in human pathogenic bacteria, such as Salmonella Typhimurium, and it works with other NAPs positively or negatively. Recently, H-NS also regulates typhoid toxin expression, which causes typhoid fever and systemic disease in human. Additionally, HU regulates the expression of genes related to both virulence and physiology of Salmonella. Therefore, we suggest that NAPs like H-NS and HU are crucial factors to reveal the molecular mechanisms of virulence gene expression in bacteria.

서울지역 보건소 간호사의 보건사업 수행활동에 관한 조사연구

박신애,양순옥,윤순녕,Park, Sin-Ae,Yang, Sun-Ok,Yun, Sun-Nyeong 한국지역사회간호학회 1989 지역사회간호학회지 Vol.1 No.1

성인 여성의 자연가족계획방법 사용에 대한 인식, 태도 및 요구도 조사

박신애,왕명자,차남현,최희정,Park, Shin-Ae,Wang, Myoung-Ja,Cha, Nam-Hyun,Choi, Hee-Chung 경희대학교 동서간호학연구소 2004 동서간호학연구지 Vol.10 No.1

Purpose: This study was attempted to investigate the demand, the recognition, and the attitude of general people on Natural Family Planning Method(NFP), and to provide basic data for a development of a program to establish a healthy sexual life. Method: This is a descriptive correlative study, collecting data by questionnaires. The subjects were 130 people of three urban areas from March 1 to April 15, 2004. The measurement tool used was about demand, recognition, and attitude to the natural birth control method. The data analysis was done by number, percent and T-test, Pearson's correlation coefficient, using SPSS program. Results: The recognition, attitude, and demand to natural birth control method was 3.01, 2.84 and 2.73 respectively. The higher recognition of correlation for natural family planning, the higher attitude(r=.864, p=.000) and demand(r= .525, p=.000) of correlation for natural family planning. It was confirmed that the study subjects almost produced self esteem and confidence recognizing at the idea of life and self value, and positively thought of need, recognition, and attitude of natural family planning method which could keep their own health management. Conclusion: As the result above, we suggest that an educational program should be developed, diffused and supported, and culturally formed by nation and social group to insist the benefit of conjugal relations in natural family planning as well as to support the knowledge deficit.

서울특별시 보건소 간호사의 인력분포와 보건사업 제공 실태에 대한 조사연구 (모자보건 가족계획 및 결핵관리 사업을 중심으로)

박신애,양순옥,윤순녕,Park, Sin-Ae,Yang, Sun-Ok,Yun, Sun-Nyeong 한국지역사회간호학회 1989 지역사회간호학회지 Vol.1 No.1

서울시 일부 보건소 결핵환자의 지식태도 실천에 관한 조사

박신애,Park Shin Ae 대한간호협회 1976 대한간호 Vol.15 No.1

Among those who were registered at the tuberculosis clinic of three health centers located in Seoul 274 patients answered the questionaires which asked for grasping their knowledge attitude & practice relative to its prevention & curing necessary for tube

양호교사의 확대된 역할

박신애,Park S.A 대한간호협회 1976 대한간호 Vol.15 No.4

지면보수교육 - 지역사회간호학편<4>관리의 기본개념 - Direction(지휘) -

박신애,Park S.A. 대한간호협회 1978 대한간호 Vol.17 No.3

대한간호지에 게재된 학교보건관계 문헌의 년도별 및 영역별 고찰

박신애,Park Sin-Ae 대한간호협회 1983 대한간호 Vol.22 No.5