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      • SCOPUSKCI등재

        Lignin 화합물의 Concrete 분산성에 대한 연구

        문정연,한기성 한국세라믹학회 1976 한국세라믹학회지 Vol.13 No.3

        Although the water mixed into the concrete plays the role of hydration and acquiring the necessary workability, the more portion of water acts to obtain the substantial workability rather than to complete the hydration. However, the excess amount of water causes the poor quality of concrete, therefore it is useful to add the minimum amount of water as required as to acquire the proper workability. There have been the considerable numbers of investigations in which the dispersion phenomena of strong eletrolytic high polymer compounds such as lignosulfate and some of surface activation agents were studied to utilize as the dispersion agent of concrete. In the present study, Na-lignate, dispersion properties of which has not been studied yet, were investigated with the purpose of utilizing as a dispersion agent of concrete. The microscopic observations showed a great improvement in the dispersion of cement particles, also the fluidity and compressive strength of concrete were remarkably increased with the addition of Na-lignate: The addition of Na-lignate by 0.02% showed the increase of 1.76 times and 1.27 times of slump value and flow value respectively, and the compressive strength was increased by 1.07 times.

      • KCI등재
      • KCI등재

        Warfarin 복용 심방세동환자의 혈액응고검사주기 연장 가능성에 관한 후향적 관찰연구

        문정연,김유리,허정원,조은정,김향숙,조윤숙,한현주,최의근 한국병원약사회 2017 병원약사회지 Vol.34 No.1

        Purpose : Patients on warfarin therapy require frequent testing to achieve therapeutic international normalized ratio (INR) range. However, excessive testing increases the burden and cost. In 2012, ACCP guideline proposed that an INR testing frequency can be done every 12 weeks for stable patients. The aim of our study was to compare the relationship between INR recall intervals after obtaining an in-range (2.0-3.0) INR and anticoagulation control for 6 months, and to evaluate the safety and feasibility of an extended interval. Methods : From May 2012 to April 2013, we retrospectively reviewed 104 patients with atrial fibrillation at the Seoul National University Hospital, whose warfarin dose had been stable for at least 3 months. Of these, 79 patients (76%) had a single out-of-range INR of ≤0.5 below or above the therapeutic range, and 25 patients (24%) had unexpected INR deviation 0.5, all of whom required a change of the maintenance dose. We compared the INR value, the time in therapeutic range (TTR), and the warfarin dose assessment between INR determinations of ≤5 weeks (short term group, n = 30) or 5 weeks (long term group, n=42). Results : The percentage of time in the therapeutic range was 62.72% in the short term group, compared to 67.29% in the long term group; there was no significant difference between the two groups (p=0.434). No increase in the biologic risk of thromboembolic or hemorrhagic events during 6 months follow-up was observed for the long term group. Conclusion : Our result suggests that for patients demonstrating a consistent pattern of stable therapeutic INRs, allowing INR recall intervals of up to ≥5 weeks does not result in increased risk for bleeding or thromboembolism. Consideration of a longer interval between INR tests for selected patients may thus be appropriate.

      • KCI등재후보

        Warfarin Therapy를 받는 환자에서 잠재적 약물상호작용 분석

        문정연,박현희,임정미,이용화,이혜숙,한현주 한국병원약사회 2015 病院藥師會誌 Vol.32 No.2

        This study investigated potential drug-drug interactions (pDDIs) with warfarin with the aim of minimizing them, and to assess the acceptability of pharmaceutical interventions by the medical team and their impact on the international normalized ratio (INR). The retrospective, observational study involved hospitalized patients (n=142) maintained on warfarin therapy with pDDI in Seoul National University Hospital from January 2012 to June 2012. Patients’demographics, medical history and medications used with daily warfarin doses were collected from electronic medical records. The pDDIs with warfarin were identified using the 9th ACCP guideline. Patients with pDDIs required lower warfarin doses than others (3.2±1.3 mg vs. 4.0±1.2 mg, p<0.05). There was a decreasing tendency for INR value in patients with pDDIs. The most common pDDIs with warfarin that resulted in increased anticoagulation were cardiovascular agents (71.8%), analgesics (16.4%), and central nervous system drugs (6.3%). Concomitant cardiovascular and analgesic drugs reduced warfarin dose requirements, compared to patients not receiving either agent (2.5±0.8 mg vs. 4.0±1.2 mg, p<0.05). The difference of INR value was 0.36 between patients treated with cardiovascular drugs and the control group. The eight patients who received pDDIs experienced bleeding complications, and displayed a higher bleeding rate than the control group (5.6% vs. 3.0%). Major and moderate pDDIs with warfarin are very common in hospitalized patients and are associated with INR level outside the therapeutic range. We conclude that concurrent use of pDDIs with warfarin is associated with increased risk of bleeding complication. Pharmaceutical interventions concerning the management of interactions by providing information to physicians can improve patient safety.

      • 긍정적 행동지원이 ADHD 유아의 문제행동 감소와 교사의 인식 변화에 미치는 영향

        문정연 한국정서행동장애학회(구 한국정서·행동장애아교육학회) 2018 정서 학습장애아교육 학술발표회 Vol.2018 No.1

        본 연구는 긍정적 행동지원이 ADHD 유아의 문제행동을 감소시키고 긍정적 행동지원과정에의 참여가 교사의 인식 변화에 미치는 영향을 분석하는데 목적이 있다. 연구 참여자는 ADHD를 가진 만 5세 남아 1명과 유아가 소속된 일반학급 담임교사였다. 연구는 행동간 중다 기초선 설계를 사용하여 기초선, 중재 단계로 진행되었다. 중재는 기능평가에 근거한 긍정적 행동지원 계획을 설정하여 진행되었으며, 표적행동은 방해하기, 계단 난간 위에 올라가기, 자리이탈 행동 세 가지로 설정하였다. 연구 결과는 다음과 같다. 첫째, 긍정적 행동지원 중재 결과 세 가지 행동 모두 평균발생빈도 및 발생률이 감소하였고, 중재의 효과는 중재 도입 후 문제행동의 빈도 및 발생률이 즉각적으로 감소되는 특징을 보였다. 둘째, 교사의 ADHD 유아의 행동특성, 지도방법, ADHD 유아에 대한 인식이 긍정적 행동지원 과정에의 참여 후에 긍정적으로 변화되었다.

      • SCOPUSKCI등재

        시멘트 초기수화과정에 대한 유기혼화제의 영향(III)

        문정연,최상홀 한국세라믹학회 1985 한국세라믹학회지 Vol.22 No.1

        The effect of calcium lignosulfonate (CLS) on the early hydration characteristics for clinker minerals was investigated. In the presence of CLS and unsufficient gypsum The hydration of $C_3$A lowered CLS adsorption to form ettrin-gite and the residual CLS in the liquid phase accelerated the solubility of C4AF hydration. As the result unreacted $Fe^{3+}$ in the liquid phase would be precipitated gelatinously on $C_3$ hydrates and the hydration of $C_3$ could be retarded. But by addition of optimum gypsum into the cement with CLS the presence of $Fe^{3+}$ in the liquid phase were lowered and $C_3$ hydration would be normallized.

      • 유아 어머니의 양육특성이 자녀에 대한 아동권리존중 실행에 미치는 영향

        문정연,전효정,류미향 한국유아교육학회 2017 정기학술대회 논문집 Vol.2017 No.-

        본 연구의 목적은 만 3세 ~ 만 5세 유아 어머니를 대상으로 자녀의 하루일과를 중심으로 아동권리존중 실행정도를 파악하고, 유아 어머니의 양육특성이 자녀에 대한 아동권리존중 실행에 미치는 상대적 영향력을 살펴보는 것이다. 연구의 결과는 유아 어머니의 자녀에 대한 아동권리존중 실행은 대체로 실행하는 편으로 나타났으며, 유아의 출생순위와 재원등록 상황, 어머니의 연령, 학력, 가정소득에 따라 어머니의 아동권리존중 실행에 차이가 나타났다. 유아 어머니의 양육특성에는 양육태도, 양육스트레스, 양육효능감으로 선정하였다. 이 가운데 양육태도의 하위요인 중 애정적 양육태도, 자율적 양육태도가, 양육효능감의 하위요인 중 인지적 효능감, 양육스트레스의 하위요인 중 자녀관계 스트레스 순으로 유아 어머니의 자녀에 대한 아동권리존중 실행에 영향을 미치는 것으로 나타났다. 즉, 어머니의 양육태도가 애정적이고, 자율적일수록, 인지적 효능감이 높을수록, 자녀관계 스트레스가 낮을수록 자녀에 대한 아동권리존중 실행정도가 높아짐을 확인하였다.

      • KCI등재

        한국어판 고틀랜드 남성우울척도의 요인분석

        문정연,제세령,윤서영 대한생물치료정신의학회 2022 생물치료정신의학 Vol.28 No.1

        Objectives:Screening of male depression is important since their symptoms differ from females, such as more common suicide attempts and aggression. Rutz et al. designed the Gotland Male Depression Scale (GMDS) to understand male depression and prevent suicide. The aim of this study is to translate the GMDS into Korean and assess the factor structure of K-GMDS. Methods:The K-GMDS was administered to 213 male office workers in one public institution. The current study used exploratory factor analysis to validate the factor structure and used confirmatory factor analysis to test the con struct validity of five factor models from prior research. Results:The result indicated that the K-GMDS is characterized by a two-factor structure, different from originally proposed GMDS factor structure and other prior models. Fit indices demonstrated the prior five models to be a poor fit to the data. The internal consistency was demonstrated by a Cronbach’s α of 0.921. Conclusions:This study can be used as a basis study of male depression, which has not been studied much in Korea. Though factor structure of GMDS reported discrepant findings with prior studies, it would help further development of the scale.

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