교재중심 강의와 문제중심학습 방식이 기초의학에서 과학적 추론에 미치는 효과 비교

김현아,김각균,이승우,Kim, Hyeon-A,Kim, Kack-Kyun,Lee, Sung-Woo 대한안면통증구강내과학회 2005 Journal of Oral Medicine and Pain Vol.30 No.1

Purpose: The aim of this preliminary study was to evaluate the effect of Problem-Based Learning (PBL) curriculum on development of comprehension of basic medical knowledge and quality of semi-structured problem solving including scientific reasoning skill. This scientific reasoning contained five components including: size of simple, design of research cause-effect, construction of risk factor, analysis statistic of data, interpretation of result. Materials and Methods: Seoul National University Dental students (100) participated in this experience during two weeks, 2004. Forty eight multiple-choice questions (MCQ) concerned "Infection Control and Prevention" were asked before and after two sections of Lecture-Based Learning (LBL) and PBL (pretest-posttest control group design). A semi-structured problem in epidemiological research was asked to these students after two sections (posttest-only control group design). Data (mean and SD) were analysed using the t Test for two independent samples (p<.05), comparing PBL versus LBL. Results: Our analyse of scores show no difference between LBL and PBL in the development of comprehension of "Infection Control and Prevention". The quality problem solving (epidemiological research) was significantly different between the two groups (p=.029); specially, two components' scores of reflection on scientific reasoning cause-effect (p=.000) and interpretation of result (p=.001) were significantly better for PBL than for LBL. Conclusion: Theses results indicate that comparing LBL and PBL, PBL curriculum have not been disadvantaged in comprehension of basic knowledge, and have contributed to develop the scientific reasoning in problem solving.

지방산 조성과 Butylated Hydroxytoluene 이 2 - acetylaminofluorene 을 투여한 쥐간의 지질 과산화물 방어 효소체계에 미치는 영향

김현아,김현덕,최혜미,이주희 ( Hyeon A Kim,Hyeon Dug Kim,Hay Mie Choi,Ju Hee Lee ) 생화학분자생물학회 1990 BMB Reports Vol.23 No.3

This study examines the effects of AAF levels and BHT on lipid peroxide metabolizing enzymes in rats fed different dietary fats. Weanling Sprague Dawley male rats were fed beef tallow and soybean oil at 15% with or without 0.3% BHT for 8 weeks. At 9th week, AAF was injected at the level of 25 ㎎ and 100 ㎎/㎏ body weight. The lipid peroxide values and cytochrome P-450 contents were determined in liver microsomal fraction, and SOD, GSH peroxidase, GSH S-transferase activities in cytosolic fraction. Effects of AAF on lipid peroxide values and SOD activities were not significantly different. GSH peroxidse activities and cytochrome P-450 contents were elevated at 25 ㎎ AAF in both dietary groups. At 100 ㎎ AAF, GSH peroxidase activities were lowered in soybean oil group, but elevated in beef tallow group. GSH S-transferase activities were elevated by AAF and correlated to the levels of AAF positively in both dietary groups. These results suggest that polyunsaturated fat diet and AAF might increase microsomal lipid peroxidation, but GSH peroxidase and GSH S-transferase activities were elevated by lipid peroxide and metabolized lipid peroxide effectively.

지방산 조성과 Butylated Hydroxytoluene이 2-acetylaminofluorene을 투여한 쥐간의 지질 과산화물 방어 효소체계에 미치는 영향

김현아,김현덕,최혜미,이주희,Kim, Hyeon-A,Kim, Hyeon-Dug,Choi, Hay-Mie,Lee, Ju-Hee 생화학분자생물학회 1990 한국생화학회지 Vol.23 No.3

이유된 Sprague Dawley종 숫쥐를 8주간 0.3% butylated hydroxytoluene(BHT)을 넣거나 넣지 않는 soybean oil과 beef tallow를 15% 수준으로 먹이고 9주째 2-acetylaminofluorene(AAF)을 복강으로 주사한 뒤 간 microsome과 cytosol 분획에서 지질 과산화물 함량, superoxide dismutase(SOD), glutathione(GSH) peroxidase, glutathione(GSH) S-trasferase 활성도와 cytochrome P-450의 함량을 측정하였다. AAF가 지질 과산화물 함량과 SOD 활성도에 미치는 영향은 두 식이군에서 유의적인 차이를 보이지 않았다. GSH peroxidase 활성과 cytochrome P-450 함량은 체중 kg당 25mg의 AAF를 투여시 두 식이군에서 모두 증가하였다. 체중 kg당 100mg의 AAF를 투여시 GSH peroxidase 활성도는 soybean oil군에서는 감소하였고 beef tallow군에서는 증가하였다. GSH S-transferase의 활성도는 두 식이군에서 모두 AAF의 투여에 비례하여 증가하였고 식이지방과 BHT는 효소 활성도에 유의적인 영향을 미치지 않았다. 이상의 결과는 불포화지방 식이와 AAF의 투여가 간 microsome의 지질 과산화를 증가시킬 것이나 지질 과산화물에 의해 cytosol의 GSH peroxidase와 GSH S-transferase의 활성도가 증가하여 지질 과산화물을 효과적으로 대사 시켰음을 시사한다. This study examines the effects of AAF levels and BHT on lipid peroxide metabolizing enzymes in rats fed different dietary fats. Weanling Sprague Dawley male rats were fed beef tallow and soybean oil at 15% with or without 0.3% BHT for 8 weeks. At 9th week, AAF was injected at the level of 25 mg and 100 mg/kg body weight. The lipid peroxide values and cytochrome P-450 contents were determined in liver microsomal fraction, and SOD, GSH peroxidase, GSH S-transferase activities in cytosolic fraction. Effects of AAF on lipid peroxide values and SOD activities were not significantly different. GSH peroxidase activities and cytochrome P-450 contents were elevated at 25 mg AAF in both dietary groups. At 100 mg AAF, GSH peroxidase activities were lowered in soybean oil group, but elevated in beef tallow group. GSH S-transferase activities were elevated by AAF and correlated to the levels of AAF positively in both dietary groups. These results suggest that polyunsaturated fat diet and AAF might increase microsomal lipid peroxidation, but GSH peroxidase and GSH S-transferase activities were elevated by lipid peroxide and metabolized lipid peroxide effectively.

주택 거래 활성화를 위한 정책 방안

김현아,Kim, Hyeon-A 한국주택협회 2006 주택과 사람들 Vol.194 No.-

하반기 부동산 시장은 기반시설, 부담금 신설 등 부동산 시장의 발목을 잡는 각종 규제가 시작된다. 이에 따라 하반기에 집을 사고 팔 계획이 있는 사람들은 이러한 제도를 충분히 염두에 두고 움직여야 한다고 전문가들은 충고한다. 하반기 부동산 시장을 움직일 변수에 대해 알아보자.

미분양으로 인한 건설사들의 경영난-빠른 대책없으면 심각한 내수 침체 가능성

김현아,Kim, Hyeon-A 한국주택협회 2008 주택과 사람들 Vol.219 No.-

건설사들이 미분양과 원자재 가격 상승이라는 '이중고'에 시달리고 있다. 지방에서 시작된 미분양이 수도권까지 확산되면서 1995년의 역대 최대 미분양 사태와 비교되며 장기화될 조짐을 보이고 있다. 대외 경제 여건 악화와 원가 상승, 금리 인상까지 겹쳐 더욱더 어려워질 것으로 보이는 건설사들의 경영난을 들여다봤다.

심.판결 사례 해설 및 평석 - 삼익악기.영창악기 간의 기업결합에 대한 대법원 판결에 대한 소고 - 1부

김현아,박진석,Kim, Hyeon-A,Park, Jin-Seok 한국공정경쟁연합회 2008 경쟁저널 Vol.- No.141

심.판결 사례 해설 및 평석 - 삼익악기.영창악기 간의 기업결합에 대한 대법원 판결에 대한 소고 ; 관련 상품시장의 획정 기준 및 효율성 항변에 관한 판단을 중심으로 - 2부

김현아,박진석,Kim, Hyeon-A,Park, Jin-Seok 한국공정경쟁연합회 2009 경쟁저널 Vol.- No.142

노인(老人) 내과환자(內科患者)의 임상통계적(臨床統計的) 고찰(考察)

김현아,정지천,이원철,Kim, Hyeon-Ah,Jeong, Ji-Cheon,Lee, Won-Chul 대한한방내과학회 1992 大韓韓方內科學會誌 Vol.13 No.1

Clinical observation was done on 496cases of the Out-patients and 136cases of the In-patients more than 65 years of age in Department of Internal Medicine, Oriental Medical Hospital in Dong Guk Univ. from March 1991 to February 1992. The results were as follows; 1. The ratio of senile (more than 65 years of age) was 16.4% in total Out-patients, was 38.1% in total In-patients. 2. The ratio of male to female was 1:1.1 in the Out-patients, In-patients was 1.2:1. The age distribution showed the large number in the 65-69 year group, the female more than the male in 70 th's group. 3. The diagnostic distribution was noted in the Out-patients as follows, Respiratory Dis. 50.6%, Cardiovascular Dis 16.4%, Brain Neurogic Dis. 14.5%, Gastrointestinal Dis. 8.1%. in the In-patients. Brain Neurogic Dis. was 76.5%, Cardiovascular Dis was 19.8%. 4. The ratio of the season distribution in the Out-patients was as follows, spring 40.2%, winter 21.2%, summer 20.9%, in the In-patients. winter was 35.9%, autumn was 25.0%, spring was 19.9%. 5. The utilization of therapeutic clinic before coming the Oriental Medical Hospital in Dong Guk Univ, was as follows, the ratio of the Out-patients was noted a hospital or clinic was 57.1%, no-treatment 22.9%, a oriental medical hospital or clinic was 8.3%. In the admission was noted no-treatment was 38.3%, a oriental medical hospital or clinic was 35.3%. 6. The ratio of the periods from onset to Out-patients department was noted within 5days was 7.3%, over 1 year was 52.6%. In the admission was noted within 1 day was 41.9%, within 7 days was 71.8%. 7. The ratio of the therapeutic periods in the Out-patients department was noted within 10 days was 48.3%, over 60 days was 7.1%. 8. The ratio of the admission periods was noted within 10 days was 45.6%, the median of the admissio was 10.8 days. Brain Neurogic Dis's median was 20.2 days. 9. The therapeutic result was noted the case of improvement was 75.7% in the admission. 10. The ratio of the Out-patients department after discharging was 53.7%, in the case of Brain Neurogic Dis. was 60.7%.

적층가공을 이용한 임시의치 제작 및 기존방식의 임시의치와의 비교 증례

김현아,임현필,강현,양홍서,박상원,윤귀덕,Kim, Hyun-Ah,Lim, Hyun-Pil,Kang, Hyeon,Yang, Hongso,Park, Sang-Won,Yun, Kwi-Dug 대한치과보철학회 2019 대한치과보철학회지 Vol.57 No.4

디지털치의학의 발달과 함께 computer-aided design and computer-aided manufacturing (CAD/CAM)을 이용한 3D 제작산업이 최근 급격한 성장을 하고 있다. 디지털 방식을 이용한 의치 제작 또한 최근의 디지털치의학 기술의 발전으로 증가하는 추세에 있다. CAD/CAM 제작방법은 크게 두가지 타입으로 나눌 수 있다: 절삭가공, 적층가공, 밀링과 같은 절삭가공은 블록 형태의 재료를 깎아 제조하는 기술을 토대로 하며, 3D printing과 같은 적층가공은 재료를 적층 방식으로 쌓아 올려 제조하는 기술을 토대로 한다. 적층가공은 밀링이 어려운 복잡한 구조의 제작에 적용할 수 있다. 본 증례에서, 적층가공방법이 레진상 총의치 제작에 이용되었다. 디지털방식을 적용한 의치의 사용기간동안 기능적, 심미적으로 만족할 만한 결과를 보여주었다. With development of digital dentistry, the 3-dimensional (3D) manufacturing industry using computer-aided design and computer-aided manufacturing (CAD/CAM) has grown dramatically in recent years. Denture fabrication using digital method is also increasing due to the recent development of digital technology in dentistry. The 3D manufacturing process can be categorized into 2 types: subtractive manufacturing (SM) and additive manufacturing (AM). SM, such as milling is based on cutting away from a solid block of materal. AM, such as 3D printing, is based on adding the material layer by layer. AM enables the fabrication of complex structures that are difficult to mill. In this case, additive manufacturing method was applied to the fabrication of the resin-based complete denture to a 80 year-old patient. During the follow-up periods, the denture using digital method has provided satisfactory results esthetically and functionally.

2008년 부동산 시장 전망

김현아,Kim, Hyeon-A 한국주택협회 2007 주택과 사람들 Vol.212 No.-