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        Anaphylaxis to topical bovine thrombin used for hemostasis during surgery for herniated nucleus pulposus −A case report−

        김혁구,이덕희,이혜미,한지수 대한마취통증의학회 2015 Anesthesia and pain medicine Vol.10 No.3

        Anaphylaxis is a type I allergic reaction and its clinical features occur after re-exposure to the same allergen. Numerous types of drugs can cause anaphylaxis during general anesthesia. Topical bovine thrombin (TBT) is usually used for hemostasis during surgery. However, TBT can cause interruption of the normal blood coagulation pathways, delay wound repair, and lead to uncontrolled bleeding, anaphylaxis, or death. Anaphylaxis caused by TBT during the perioperative period is very rare. We report the case of a patient who developed severe hypotension, tachycardia, and bronchospasm while undergoing discectomy for herniated nucleus pulposus. Based on the symptoms and signs, anaphylaxis was considered most likely. Identification of the causative agents is important in these cases because it can be very helpful for the management and prevention of anaphylaxis.

      • KCI등재

        Comparison of sevoflurane and propofol anesthesia on the incidence of hyperglycemia in patients with type 2 diabetes undergoing lung surgery

        김혁구,한지수,정성미,박상진,권녕건 영남대학교 의과대학 2018 Yeungnam University Journal of Medicine Vol.35 No.1

        Background: The type and regimen of anesthesia may affect perioperative hyperglycemia following major surgical stress. This study compared the effects of sevoflurane and propofol on the incidence of hyperglycemia and clinical outcomes in diabetic patients undergoing lung surgery. Methods: This retrospective study included 176 patients with type 2 diabetes mellitus who had undergone lung surgery. Blood glucose levels and clinical outcomes from the preoperative period to the first 2 postoperative days (PODs) were retrospectively examined in patients who received sevoflurane (group S, n= 87) and propofol (group P, n=89) for maintenance of general anesthesia. The primary endpoint was the incidence of persistent hyperglycemia (2 consecutive blood glucose levels >180 mg/dL [10.0 mmol/L]) during the perioperative period. The secondary composite endpoint was the incidence of major postoperative complications and 30-day mortality rate after surgery. Results: Blood glucose levels similarly increased from the preoperative period to the second POD in both groups (p=0.857). Although blood glucose levels at 2 hours after surgery were significantly lower in group P than in group S (p=0.022; 95% confidence interval for mean difference, -27.154 to -2.090), there was no difference in the incidence of persistent hyperglycemia during the perioperative period (group S, 70%; group P, 69%; p=0.816). The composite of major postoperative complications and all-cause in-hospital and 30-day mortality rates were also comparable between the two groups. Conclusion: Sevoflurane and propofol were associated with a comparable incidence of perioperative hyperglycemia and clinical outcomes in diabetic patients undergoing lung surgery.

      • KCI등재

        General anesthesia for an adolescent with Pelizaeus–Merzbacher disease - A case report -

        김혁구,임채석 대한마취통증의학회 2019 Anesthesia and pain medicine Vol.14 No.1

        Pelizaeus-Merzbacher disease (PMD) is a progressive and degenerative chromosomal disorder of the central nervous system caused by defective myelin production. Few case reports have been issued on the anesthetic management of PMD, because of its extremely low incidence. We anesthetized a 13-year-old female patient diagnosed with PMD for ophthalmic surgery because of intermittent exotropia. General anesthesia was induced and maintained with propofol and sevoflurane in air and oxygen. Rocuronium was administered to facilitate orotracheal intubation, and residual neuromuscular blockage was reversed with pyridostigmine. Between emergence to 24 hours postoperatively, her muscle power completely recovered and no unpredictable events occurred. Summarizing, anesthesiologists should be concerned about the high possibility of aspiration, spasticity, and seizure during the perioperative period in patients with even mild PMD. Appropriate preoperative evaluation, intraoperative monitoring, and choice of proper anesthetic drugs enable safe anesthesia in patients with PMD.

      • 공인중개사제도의 선진화

        김혁구 국제부동산정책학회 2012 토지와건물 Vol.26 No.-

        I suggested the advancement aspect of licensed real estate agent as expertise and quality improvement of licensed real estate agent and the scale enlargement of brokerage. The expertise of licensed real estate agent should bestow the role on the test qualified persons according to the law. Hence they can develop and improve their expertise with their unique duty of the license. The quality improvement is poor causing from present lots of test qualified people situation related with the legal training. So prominent hands-on-background persons should be able to select officers of brokerage corporate and establish a brokerage office. The enlargement of brokerage can be freely introduced through the regulation improvement of the small capital and officer selection, and regulation dominant system as well as one of profit structure that the current law bears. The advanced development could be brought in brokerage market through the establishment of enlarged brokerage corporate by management specialists under changed structure with the influx of people in along with capital. The business enrollment of licensed real estate agent should be considerably enforced. Such as other local expertise’s business enrollment and practical experience, the qualified ones of licensed real estate should be able to apply for business enrollment since 3-year hands-on-background. Consequently, it will prevent application for the license test lacking of any definite plan, and reduce the number of brokerage offices which is overflowed adequately, and hinder planning real estate, nonlicensed brokerage offices, problem of brokerage assistant (those who are hired as practical in-service trainees), in particular be helpful to the monetary loss from the frequent openings by the test qualified as well as be useful for finding out employees for offices and corporate. Ultimately it will be the result that brings the quality improvement of licensed real estate agents.

      • KCI등재

        Unusual excessive sweating and hypothermia during hysterectomy under general anesthesia -A case report-

        김혁구,지대림,이혜미 대한마취통증의학회 2015 Anesthesia and pain medicine Vol.10 No.4

        A 78-year-old female patient was undergone general anesthesia for total abdominal hysterectomy with bilateral salpingo-oopherectomy. Arterial blood pressure dropped 20 minutes after beginning of the surgery when uterine manipulation was started. From then, excessive sweating was found in the face and whole body and core temperature decreased to 34.3oC. Sweating and low body temperature were sustained despite of various aggressive warming efforts. Anticholinergic medication immediately put an end to an hour of excessive sweating and prevented further body temperature decline. Several possibilities of excessive sweating were discussed in this case: uterine manipulation during the light plane of general anesthesia, age related autonomic changes, use of intraoperative opioid and antihypertensive medications.

      • KCI등재

        시한부분묘제도의 정착화 방안에 관한 연구

        김혁구(Kim, Hyuk Koo),민규식(Min, KYu Sik) 한국부동산학회 2009 不動産學報 Vol.39 No.-

        1. CONTENTS (1) RESEARCH OBJECTIVES This study is intended to investigate the task of the time-limited burial treatment to prevent the confusion since the time limit of Jan 12, 2016 when the current time0limited burial system is applied first and to establish the measure for it (2) RESEARCH METHOD This study attempted to make a general investigation of the time-limited burial system by reference to all sorts of materials, make a close analysis of the contents of related statutes related to the time-limited burial system and the background for its introduction and identify the present situation of the tombs and its realities. (3) RESEARCH FINDINGS To induce the time-limited burial system to take root, this study attempted the following improvement scheme: First, it is necessary to compile the tomb register as the basic material through the report of all tombs in order to introduce the time0limited burial system. Second, it is thought that 20 years is adequate as the concept of one generation by reducing the period of time-limited burial to a maximum of 60 years as the scheme to improve the extension of time limit. Third, it is necessary to establish the effectiveness of improvement of illegal tombs by defining matters concerning the presence or absence of their registration in the tomb register and of permission or notification of tomb installation, and the authority to install the tomb as the improvement scheme to identify relations to the tomb. Fourth, it is necessary to apply the time-limited burial system as 100 years as the basis in order to improve tombs prior to the enforcement of the time-limited burial system. Fifth, setting the maximum of 120 years as the period of burying together by starting the calculation of its period at its point in time is likely to make the time-limited burial system useless. So it is necessary to adjust it to the reasonable period. Six, it is necessary to enforce the time-limited burial system to fit the emotional practice of people a little more. For this purpose, it is necessary to introduce the system to install the burying-together bomb for the family capable of housing less than 150 persons or so in one tomb ot prevent the burden of abolishing the tombs at a time such as reburial. 2. RESULTS It is necessary to enforce the expired tomb when the period of tomb installation is expired as prescribed. For this purpose, efforts should be made to secure the effectiveness of law enforcement and induce the system to take root. Among other things, efforts should be made to change people's deep-rooted consciousness of the burial system.

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