보기, 보양, 온리약의 전처치가 glutamate current에 미치는 영향

김창주,김연정,김현배,김이화,이충열,Kim, Chang-Ju,Kim, Youn-Jung,Kim, Hyun-Bae,Kim, Ee-Hwa,Lee, Choong-Yeol 대한동의생리학회 1999 동의생리학회지 Vol.14 No.2

The effects of Bogi, Boyang and Onri herbs on glutamte receptor, and the regulatory mechanism of cAMP-protein kinase on the ion currents activated by Bogi, Boyang and Onri herbs using nystatin-perforated patch clamp were investigated and the following results were obtained. Ginseng radix and Astragali radix, Cervi cornu and Boshniakiae herba, and Aconiti tuber and Zingiberis rhizoma were chosen as Bogi, Boyang and Onri herbs respectively. 1. The ion currents activated by $10^{-5}M$ of glycine were used as controls. The magnitudes of the ion currents by the above named herbs were as follows; Cervi cornu>Astragali radix>Aconiti tuber>Zingiberis rhizoma>Ginseng radix>Boshniakiae herba. 2. The magnitudes of the ion currents by $10^{-5}M$ of glutamate pre-treated with 0.01 mg/ml of Bogi, Boyang and Onri herbs were sharply decreased. 3. The activity of ion channels activated by Bogi herbs pre-treated with $10^{-7}M$ of staurosporin, an inhibitor of protein kinase, for thirty seconds was observed as the experiment proceeded. Staurosporin brought about dephosphorylation of ion channels. Hence, while the activity of ion channels activated by Ginseng radix was decreased, the activity of ion channels activated by Astragali radix was increased, as time went by. 4. The activity of ion channels activated by Boyang herbs pre-treated with $10^{-7}M$ of staurosporin, an inhibitor of protein kinase and an dephosphorylating agent of ion channels, for thirty seconds was investigated. While the activity of ion channels activated by Cervi cornu was increased, the activity of ion channels activated by Boshniakiae herba was initially increased then sharply decreased. 5, The activity of ion channels activated by Onri herbs pre-treated with $10^{-7}M$ of staurosporin, an inhibitor of protein kinase and an dephosphorylating agent of ion channels, for thirty seconds was investigated. While the activity of ion channels activated by Aconiti tuber was increased, that of ion channels activated by Zingiberis rhizomal sharply declined.

Effects of swimming on functional recovery and brain-derived neurotrophic factor (BDNF) mRNA expression after sciatic crushed nerve injury in rats

김창주,Lee, Myoung-Hwa,Byun, Yong-Hyun,Yoon, Bum-Chul,Kim, Chang-Ju 대한물리치료학회 2004 대한물리치료학회지 Vol.16 No.2

말초신경은 외상이나 질병 등 여러 가지 원인으로 손상되기 쉬우며, 손상의 정도가 심하거나 치료가 지연되는 경우에는 심각한 기능 소실을 초래할 수 있다. 본 연구에서는 수영이 말초신경손상후 운동기능의 회복과 뇌유인성 신경영양인자 (brain-derived neurotrophic factor, BDNF) mRNA의 발현에 미치는 효과를 알아보기 위하여, 흰쥐 좌골신경에 압박 손상을 가하고 수영을 적용한 후 보행궤적분석 (walking track analysis)과 역전사연쇄반응 (reverse transcription-polymerase chain reaction, RT-PCR)을 실시하였다. 그 결과, 좌골신경 압박손상된 쥐는 특징적인 보행패턴을 나타내어 좌골신경기능지수 (sciatic function index, SFI)가 현저히 낮아졌으며, BDNF mRNA의 발현이 증가하였다. 좌골신경 압박 손상후 수영을 한 쥐에서는 SFI가 현저히 향상되었으며, BDNF mRNA의 발현은 억제되었다. 이러한 결과는 말초신경손상후 수영이 BDNF mRNA의 발현을 조절함으로써 기능 회복을 촉진시키는 효과적인 치료방법이 될 수 있음을 제안하고 있다.

$2frac{1}{4}$Cr-1Mo 강관(STBA23)의 Low cycle 피로특성에 관한 연구

김창주,Kim, Chang-Ju 한국기계연구원 1984 기계연구원소보 Vol.12 No.-

Cognitive Radio 기술 동향

김창주,Kim, C.J. 한국전자통신연구원 2006 전자통신동향분석 Vol.21 No.4

유비쿼터스 정보화사회의 도래와 함께 한정된 주파수자원에 대한 수요가 증가됨에 따라 이를 효율적으로 이용하기 위한 기술이 더욱 각광을 받고 있다. 이중에서도 스펙트럼 환경을 측정하여 사용하지 않은 주파수를 선정, 기존의 전파환경과 양립하면서 통신을 하는 CR 기술은 미래 무선통신의 핵심 기술로 인식되고 있다. CR 기술은 SDR 기술을 기반으로 스펙트럼 센싱(spectrum sensing) 기능을 활용하여 가용한 주파수를 선정하여 통신하는 기본적인 기능과 여러 가지 환경 파라미터를 지속적으로 업데이트하는 learning algorithm이 합쳐진 기술이다. 본 고에서는 CR 기술을 설명하고, CR의 응용으로 현재 표준화가 진행되고 있는 IEEE 802.22 WRAN 표준화 활동과 WG에서 검토되고 있는 기술, 즉 physical layer, MAC layer, 그리고 spectrum sensing의 주요기술을 소개한다.

신금속재료(2)

김창주,한승전,Kim, Chang-Ju,Han, Seung-Jeon 재료연구소 1998 機械와 材料 Vol.10 No.1

고급 주물용 알루미늄 합금제조 기술 현황

김창주,박수현,Kim, Chang-Ju,Park, Su-Hyeon 재료연구소 1990 機械와 材料 Vol.2 No.4

Perennial ryegrass 의 파종비율을 달리한 혼파 목초지에 있어서 목초생장 및 식생구성비율의 계절적 변화

김창주,김동암 ( Chang Ju Kim,Dong Am Kim ) 한국축산학회 1977 한국축산학회지 Vol.19 No.3

This experiment was carried out to investigate seasonal variations in the plant growth and botanical composition of the mixture swards of orchardgrass/perennial ryegrass/Ladino clover sown at different seeding rates of perennial ryegrass. Five kinds of seeds mixture of orchardgrass 20 ㎏/㏊ Ladino clover 3 ㎏/㏊ added with 0 ㎏/㏊ (P-0), 5 ㎏/㏊(P-5), 10 ㎏/㏊(P-10), 20 ㎏/㏊(P-20) and 30 ㎏/㏊(P-30) of perennial ryegrass were sown in the experimental field of Kangwon National University on the 24th of April in 1972. The experimental mixture swards were cut once a month from June to October in the First harvest year (1972) and from April to October in the second harvest year (1973). The results obtained were summarized as follows: 1. Establishment ratio of orchardgrass and Ladino clover showed a tendency to drop as the seeding rate of perennial ryegrass rises. Orchardgrass and Ladino clover seemed to be oppressed already one month after the sowing by perennial ryegrass which was vigorous in early stage growth. 2. All the plants of the mixture shards had an inclination to show shorter plant length in spring and autumn, yet longer in summer. Perennial ryegrass showed comparatively little variation in the plant length throughout the growing period, while orchardgrass and Ladino clover marked large variation. 3. In the first harvest year, until the early summer the botanical composition ratio of perennial ryegrass marked 14.1% in P-5, 27.2% in P-10, 47.3% in P-20 and 63.7% in P-30 but after the midsummer the ratio dropped remarkably to 7.4%, 17.7%, 28.7% and 44.1% respectively. 4. Perennial ryegrass revealed poor summering and wintering record; it mostly disappeared after the midsummer of the second harvest year. 5. In the first harvest year, as seasons progressed from spring to autumn the ratio of perennial ryegrass in the botanical composition had a tendency to decrease in the plots sown under 10 ㎏/㏊ of perennial ryegrass but the ratio tended to increase in the plots sown more than 20 ㎏/㏊ of perennial ryegrass while the ratio of Ladino clover rised in every plots. 6. In the second harvest year, all through the growing seasons orchardgrass and Ladino clover maintained their botanical composition ration relatively equal except for the temporary dropping in orchardgrass` ratio in May and June and temporary rising in Ladino clover`s ratio in the same months. 7. Until the early summer of the second harvest year the botanical composition ratio inclined to drop in orchardgrass and Ladino clover and to rise in perennial ryegrass in proportion to increase in seeding rate of perennial ryegrass, but after that time difference of the botanical composition derived from the different seeding rates of perennial ryegrass was not noticed among the plots.

Al-Si-Mg (A356) 주조합금의 파괴인성 및 피로균열전파에 미치는 응고속도의 영향

김창주,김정근 ( Chang Joo Kim,Chung Keun Kim ) 한국주조공학회 1991 한국주조공학회지 Vol.11 No.1

N/A Aluminium alloy castings, which can be not only manufactured in larger geometrically complex shapes, but also show good mechanical properties in addition to light weight, have kept their potential use as structures in the field of automotives, industrial machines and aircrafts. The variations of eutectic Si size a great effect on the elongation, impact value, fracture toughness and fatigue crack propagation rate without changes in the tensile strength or yield strength. The cooling curves with the solidification rate between 1.4℃/min and 19.1℃/min were obtained. With the increase of solidification rate, DAS, eutectic Si size and grain size were all decreased, which enhanced the mechanical properties. The tensile strength and yield strength were the most greatly influenced by DAS, and the elongation and impact value by eutectic Si size.

New Zealand 산 도입목초의 강원지역에 있어서 적응성 비교시험

김창주,장병호,이창덕 ( C . J . Kim,B . H . Chang,C . D . Lee ) 한국축산학회 1978 한국축산학회지 Vol.20 No.3

A comparative experiment was carried out in Chunchon and Taekwanryong, Kangwondo to test the adaptability of pasture plants introduced from New Zealand. The New Zealand introduced pasture plants tested in this experiment were orchargass-Apanui(O-A), perennial ryegrass-Ruanui(P-R), Tama ryegrass(Ta), timothy-Kahu(Ti-K), white clover-Huia(W-H), alsike clover(As), red clover-Hamau(R-H) and alfalfa-Wairau(Af-W); besides those plants U.S.A. introduced orchardgrass-Potomac(O-P) and Ladino clover(L), Canada introduced perennial ryegrass-Norlea(P-N) and Australia introduced tall fescue-Demeter (Tf-D) were included in this experiment to compare with the New Zealand introduced pasture plants. The Chunchon experimental field(94m above sea level) was sown on the 8th of May 1977 and the Taekwanryong experimental field(820m above sea level) on the 10th of 1May 1977, and the experiment was carried on until April 1978. The results obtained were summarized as follows: 1. O-A and P-R were slower in early stage growth, lower in the year total yield of dry matter and poorer in wintering record than O-P and P-N respectively. 2. O-A and P-R seemed to unsuitable varieties for the Kangwon area. 3. Ta, which proved to be annual, was thought to be utilized sooner after the sowing because its early stage growth was extremely vigorous. 4. Ta demonstrated abundant production marking 10.99 t/㏊ in the year total yield of dry matter in the Taekwanryong experimental field. Nevertheless, Ta`s summering record was inferior in the Chunchon experimental field. 5. In the both experimental fields of Chunchon and Taekwanryong, Ti-K showed a poor record in summering and presented a low year total yield of dry matter but it was found to be outstanding in winter survival. 6. W-H was regarded to have the strongest winter hardiness among the legume plots, yet it marked rather a lower dry matter yield. 7. It is presumed that R-H will find no difficulty in wintering even in the alpine region but will fall into trouble in summering in the lowlands. 8. Af-W made poor growth in both the Chunchon and Taekwanryong experimental field. 9. Though L recorded the highest year total yield of dry matter among the legume plots, most of L were winterkilled in the Taekwanryong experimental field. 10. O-P and Tf-D presented comparatively good record in summering and wintering, and Tf-D showed the highest year total yield of dry matter in the Chunchon experimental field presenting 6.01 t/㏊. 11. P-N and As revealed comparatively strong winter hardness even in the Taekwanryong experimental field. 12. In the year total yield of dry matter the Taekwanryong experimental field was larger than the Chunchon experimental field by 79.1% in the grasses and by 13.8% in the legumes.

신 금속재료(1)

김창주,정윤철,Kim, Chang-Ju,Jeong, Yun-Cheol 재료연구소 1997 機械와 材料 Vol.9 No.3