Atorvastatin으로 유도된 근위축 세포모델에서 상황-오미자박 고상발효물 열수추출물의 보호효과

김영숙,황수진,박광일,임종민,천다미,정유진,전병엽,곽경태,오태우,Kim, Young-Suk,Hwang, Su-Jin,Park, Kwang-Il,Lim, Jong-Min,Cheon, Da-Mi,Jung, Yu Jin,Jeon, Byeong Yeob,Kwak, Kyeung Tae,Oh, Tae Woo 대한한의학방제학회 2021 大韓韓醫學方劑學會誌 Vol.29 No.4

Objectives : This study is to effect of improving muscle atrophy through water extract on the solid-phase fermentation extraction with Phellinus linteus of discarded Schisandra chinensis in an atorvastatin-induced atrophy C2C12 cell. Methods : C2C12 myoblast were differentiated into myotube by 2% horse serum medium for 6 days, and then treated solid-phase fermentation(S-P) extract at different concentrations for 24h. To investigate the effect of S-P extract on the induction of muscle atrophy and expression of atrophy-related genes and apoptosis in differentiated C2C12 myotubes using a GSH, ROS, real-time PCR, western blots analysis. Results : As a result of treatment with atorvastatin at concentrations of 5, 10, and 20 uM on the 6th day of differentiation in C2C12 myotube cells, it was confirmed that the cell morphology was damaged in a concentration-dependent manner, and the length and thickness of the myotube also decreased in a concentration-dependent manner. Treatment with S-P extract (50, 100 and 200 ㎍/㎖) increased of GSH and inhibited ROS in the atorvastatin-induced muscle atrophy cell model at a concentration that did not induce toxicity. In addition, it was confirmed that it has an effect on muscle reduction by inhibiting apoptosis of muscle cells as well as being involved in protein production and degradation of muscle cells. Conclusions : Atorvastatin-induced atrophy C2C12 cell, S-P extract activates related to differentiation/generation and proteolysis, and inhibits cell death of atrophy in C2C12 cell. Based on this, it is necessary to prove its effectiveness through animal models and human application test, but it is considered to be discarded Schisandra chinensis can present the potential for development as a recycling industrial material.

부산지역 방문간호사업 실태에 관한 연구

김영숙,박정란,박형숙,이윤미,Kim, Young-Suk,Park, Jung-Ran,Park, Hyoung-Sook,Lee, Yun-Mi 한국가정간호학회 2004 가정간호학회지 Vol.11 No.1

Purpose: The purpose of this research is to give basic data about a way of connection to individual centers and vitalization of visiting nursing program on Busan. Method: The research is done with survey for eight hospitals. sixteen public heath centers, forty-six social welfare centers to be practised visiting nursing program on Busan for actual condition of that. Results: 1. The average nursing career is below 5-10 years. But visiting nursing career is below 3 years(70%) in hospital. public, public heath center, and heath center. 2. Hospitals coverage of visiting nursing service is city as a whole. Whereas public heath center and social welfare center covered some local area. 3. Client of visiting nursing service possess in order of alone lived elderly, person in uncomplete movement, a disabled person, and a chronic disease person. 4. The main service in visiting is patient assessment, basic nursing activity, and treatment nursing activity with medication care, B.P check, dressing, bedsore care, catheter care and exchange, fluid therapy. Particularly, the hospital runs parallel to basic care and treat care in 100%. The social service center has 65.0% in a patient assessment and basic nursing activity. 5. The concern about services connecting with other center is very high. Conclusion: Actual conditions of visiting nursing program on Busan, which is presented in this study. The results of this study will become the pillar of visiting nursing program planning and application.

웹툰 〈은밀하게 위대하게〉의 스토리텔링에 나타난 일상성

김영숙(Kim, Young-Suk) 한국애니메이션학회 2017 애니메이션연구 Vol.13 No.3

최근 디지털의 발달과 함께 등장한 웹툰은 대중문화로서 현대인들에게 일상생활 속의 친숙한 콘텐츠 역할을 하고 있다. 온라인을 통해 범위를 넓혀 가며 영역을 확장하고 있는 웹툰은 영화나 TV드라마, 뮤지컬 등을 통해 많은 다른 매체로 변환되어 향유자들에게 전달되고 있다. 웹툰의 문화적 파급력이 확장되고 지속적인 활성화를 성취하려면, 인터넷 환경에 따른 변화와 사용자들의 변화된 특성을 고려한 웹툰 제작이 중요한 관점이 될 것이다. 본 연구는 웹툰에 함축되어 표현된 스토리의 핵심요소인 일상성을 논의하기 위해 웹툰의 장르적 특징과 일상성의 특징을 분석하여 향유자의 이해를 돕고 웹툰의 문화적 위상을 높이는 데에 목적이 있다. 연구 방법으로는 웹툰의 특징과 일상성, 웹툰 장르 자체가 가진 매체의 환경적 특성, 그로 인한 향유 패턴의 변화에 대해 분석하고, 웹툰 〈은밀하게 위대하게〉에 나타난 서사구조, 캐릭터 구도, 공간의 성격화, 인물구성과 상황의 딜레마, 사실적인 공간 배치와 상징적인 셔레이드 유형을 통하여 웹툰에 표현된 일상성 분석에 접근하였다. 연구 결과, 웹툰의 일상성의 특징은 개인화 추세, 편의성과 접근성, 일상적인 소재 등으로 볼 수 있다. 웹툰만의 특징인 세로읽기를 통해 매체환경과 공간의 여백을 적극적으로 활용하여 심미적 아름다움과 자유로운 공간 구성과 서사를 펼치고, 불연속적인 연재 방식은 예고편이나 셔레이드를 통해 극복하였다. 또한, 셔레이드의 유형을 통해 주제의 암시, 캐릭터의 형상, 관계 상징, 상황의 암시, 이미지의 대사화 등을 연출함으로써 향유자의 적극적인 향유를 가능하게 했다. 최종훈만의 상징적 대사 구현, 강렬한 색감과 독특한 조형미로 스토리텔링을 이끌어 내고, 섬세한 캐릭터의 묘사를 통해 일상성에 대한 적극적이고 확장된 향유를 가능하게 하였으며 ‘일상성’의 개념과 중요성을 부각시킨 것으로 분석된다. 오늘날 계속 새롭고 다양해지고 있는 매체환경과 문화 콘텐츠뿐만 아니라 미디어가 나날이 최적화되는 방향으로 전환되는 시점에서 웹툰은 일상성에 대한 깊이 있는 표현으로 이루어져야 한다. 다양한 모습의 캐릭터 연출로 향유자들에게 일상성의 다양하고 진한 감동과 정보가 향유되도록 해야 한다. 또한 웹툰이 향유자들의 쉼터역할을 해 주며 삭막해져 가는 현대인들의 마음을 순화할 수 있는 장르로서의 역할을 하기를 기대한다. With the development of digital system, the recent webcomic has played a role of familiar contents in modern people’s everyday life as public culture, Webtoon, which has been expanded through online service, has been provided to readers by being transferred to another type of media such as movies, Tv dramas or musicals. For continuous revitalization and cultural ripple effect of Webtoon, webcomic artists have to take account into user’s changed characteristics, which Internet environment caused. This study aims to analyze features of genre of webtoon and features of dailiness in this webtoon to discuss dailiness which is the core implied stories in webtoon. First of all, I will do analysis of the environmental features which webtoon itself has and the changes of the enjoyment patterns. And then, I will also analyze the dailiness expressed in webtoon 〈Secretly, Greatly〉through narrative structure, character composition, characterization of space, characters` duplicity and dilemma, realistic space arrangement and type of a symbolical charade, According to the research result, webtoon shows aesthetic beauty and free narration with space constraints, utilizing media environment and blank space through vertical reading, which is webtoon’s unique feature. Also, webtoon is overcoming discontinuous serial publication method in the way of a preview and charade and it encourages readers` enjoyment to strongly last, creating suggestion of theme from the type of charade, characters` shape, implication of events and dialogue of images. Webtoon generates storytelling through unique beauty of a structure and outstanding colors, therefore it has a signification that users can enjoy the theme actively and deeply through delicate descriptions of characters. Today, the media environment and the cultural contents are constantly diversifying. Thus, webtoon should provide modern people with enjoyment of feeling moved by analyzing dailiness in depth and describing various daily lives of ordinary people at this point of time, I expect webtoon to play a role not only as shelter in which users relieve their stress but also as genre which purifies user’s heartless mind.

골프 스윙 시 클럽 형태에 따른 하지 동작의 생체역학적 특징 분석

김영숙 ( Kim Young-suk ),( Wu Chaojie ),김석원 ( Kim Suk-won ) 한국융합과학회 2022 한국융합과학회지 Vol.11 No.8

연구목적 본 연구는 드라이버 또는 7번 아이언 골프스윙 시에 나타나는 하체의 운동학적, 운동역학적 변인들을 비교분석하여, 이를 바탕으로 스윙의 차이점을 탐색하는 것에 목적이 있다. 연구방법 이를 위해 6명의 주말 골퍼들이 드라이버 또는 7번 아이언을 스윙할 때 운동학적, 운동역학적 변인을 수집하였다. 운동학적 변인을 수집하기 위해서 열세개의 Optitrack Prime 17를 이용하였고, 운동역학적 변인을 수집하기 위해서 두 개의 AMTI 지면반력기를 이용하였다. 각각의 골퍼들은 드라이버 또는 7번 아이언을 5번 스윙하였고 그 중에서 가장 좋은 3개의 평균을 데이터분석에 사용하였다. 결과 운동학적, 운동역학적으로 드라이버와 7번 아이언의 스윙에는 차이가 있었다. 피험자가 드라이버를 사용하여 스윙할 때는 7번 아이언에 비교하여 상대적으로 더 큰 고관절와 무릎 굴곡 각도, 더 작은 발목 각도 및 더 작은 수평 지면반력이 나타났다. 스윙 중 운동사슬(Kinetic Chain)은 두 유형의 클럽에서 일관적으로 나타났으며, 이 때 오른쪽에서는 최대 무릎 굴곡 각도를 피니시 구간에서는 최대 고관절 각도가 발생했다. 이는 임팩트 시 고관절이 완전히 펴지고 몸이 등 아치를 만들어내면서 최대의 효율로 스윙을 완성했기 때문으로 사료된다. 결론 본 연구는 골프채에 따라 스윙의 변화가 있음을 시사하였고, 본 연구의 결과로 추론해 볼 때, 골프 코치는 초보 골퍼를 지도할 때 하체 움직임의 변화를 먼저 교정하는 것이 이익이 될 수 있다는 결론을 내렸다. Purpose The purpose of this study is to compare and describe the lower limbs biomechanical characteristics of golfers swing with different types of clubs. Methods The present study compared the biomechanical data of recreational golfers when swinging with either a drivers and a 7-iron. The kinematic and kinetic data were collected by using an infrared motion capture system and AMTI force plaforms at 360 Hz. Result The study found that there were differences between the swing of a driver and a 7-iron. When the folders used a driver, the larger hip and knee flexion angles, smaller ankle angels and the smaller horizontal GRF than a seven-iron was a vital factor to hit the ball better than a 7-iron. The kinematic chain during each swing was consistent for different types of clubs, with the maximum knee flexion angle on the right side and the maximum hip angle occurring at finish. This was due to the fact that during the time of impact, the hip joint was fully extended and the body created a back arch, thus, completing the swing with maximum efficiency. Conclusion The present study suggested that different golf clubs resulted in changes in swings and concluded that golf coaches could start by working on lower body movements when coaching novice golfers.

핵심기본간호술 재교육이 간호대학생의 자기주도적 학습능력, 자기효능감, 핵심기본간호술 수행자신감에 미치는 효과

김영숙(Young Suk Kim),조은주(Eun Joo Jo),최은정(Eun Joung Choi),한정원(Jeong Won Han) 고신대학교 전인간호과학연구소 2018 전인간호과학학술지 Vol.11 No.-

Purpose: The purpose of this study is to identify the effect of reeducation of core fundamental basic nursing skills on self-directed learning ability, self-efficacy and self confidence of senior nursing students. Methods: The subject of this study was 107 senior nursing students at college of nursing, Busan, South Korea. The self-directed learning ability, self-efficacy and confidence of core fundamental nursing skill performance of nursing students before and after the reeducation were evaluated using the structured survey. Results: As a result of the study, the self-directed learning ability and self confidence were significantly improved. Conclusion: Therefore, reeducation of core fundamental basic nursing skills will contribute as a nursing practice education.

성인의 흡연행태와 치주염의 관련성

김영숙 ( Young-suk Kim ),민희홍 ( Hee-hong Min ) 한국치위생학회 2016 한국치위생학회지 Vol.16 No.6

Objectives: The purpose of the study was to examine the relationship between smoking behavior and periodontitis in Korean adults. Methods: The study subjects were 4,896 from the sixth Korean National Health and Nutrition Examination Survey. Data were analysed by chi-square test and multiple logistic regression analysis using SPSS 20.0 program. Results: The rate of periodontitis was 27.5%. The prevalence rate of periodontitis was closely related to socio-economic characteristics including gender, age, living area, household income, educational level, history of diabetes mellitus, and regular dental visit. The rate of periodontitis in non-smoker, ex-smoker, and current smoker were 56.7%, 19.5%, and 23.8%, respectively. Smoking behavior was significantly related to socio-economic characteristics. After adjusting for gender, age, household income, educational level, history of diabetes mellitus, and dental visit within 1 year, the risk of periodontitis in ex-smoker and current group were 1.31 (95% CI; 1.04-1.65) and 2.31 (95% CI; 1.87- 2.85), respectively. Conclusions: Smoking behavior had a significant impact on periodontitis prevalence in Korean adults.

당뇨와 지역사회치주지수의 관련성: 제5기 국민건강영양조사

김영숙 ( Young Suk Kim ),전지현 ( Ji Hyun Jeon ),민희홍 ( Hee Hong Min ) 한국치위생학회 2014 한국치위생학회지 Vol.14 No.6

Objectives: The purpose of the study was to examine the association between diabetes mellitus and community periodontal index in Korean adults. Methods: The study populations were recruited by the Fifth Korea National Health and Nutrition Examination Survey. Study subjects were 10,411 who were examined oral examination, blood test, and aged over 19 years. Using multiple logistic regression analyses, the variables were adjusted for gender, age, household income, family history of diabetes, body mess index, smoking habit, and frequency of tooth brushing. Periodontal tissue examination of the subjects was performed and scored by Community periodontal index(CPI). Using probe, six teeth were examined for hemorrhage, plaque, and pocket depth and classified into CPI0, CPI1, CPI2, CPI3 and CPI4. Healthy periodontal groups(CPI0-2) and periodontal disease groups(CPI3-4) were divided by the periodontal disease status. The definition of diabetes mellitus(DM) was decided by the diagnosis by the doctors and fasting blood sugar level. Those who were diagnosed as DM were included in DM group. The DM variables included normal blood sugar level, increased fasting blood sugar level, and DM blood sugar level. The DM variables were compared to periodontal disease blood sugar level and analyzed. Results: The periodontitis prevalence rate was 23.2%. Those who had diabetes mellitus accounted for 5.5% of the subjects. Those who had impaired fasting glucose accounted for 17.7% and 7.9% of subjects were diabetes mellitus by blood test. In the confirmed diabetes group by doctor, the periodontitis prevalence rate was significantly higher than the non-diabetic group. Diabetic group by blood test had the highest prevalence rate of periodontitis than those who had impaired fasting glucose group or normal group. After adjusting for gender, age, household income, family history of diabetes, body mass index, smoking habit, and frequency of tooth brushing, the risk of periodontitis in diagnosed diabetes mellitus was 1.57 times(95% CI; 1.27-1.94) higher than the normal group. In impaired fasting glucose group and diabetes mellitus group by blood test, the risk of periodontitis was 1.11 times(95% CI; 0.95-1.30) and 1.45 times(95% CI; 1.45-2.12) higher, respectively. Conclusions: There was a significant relationship between diabetes mellitus and periodontitis in Korean adults. These results suggest that diabetes mellitus is a risk factor for periodontitis.

유아교사의 직무스트레스가 조직몰입에 미치는 영향에 있어 교수효능감의 매개효과

김영숙(Kim, Young-Suk),정명선(Chung, Myung-Sun) 한국산학기술학회 2014 한국산학기술학회논문지 Vol.15 No.3

본 연구는 유아교사의 직무스트레스, 교수효능감, 조직몰입의 관계를 밝히는 데 목적을 두고, 특히 유아교사 의 직무스트레스가 조직몰입에 미치는 영향에 있어 교수효능감의 매개효과를 살펴보고자 하였다. 이를 위해 D광역시 소재 유치원과 어린이집 유아교사 각 250명씩 총 500명을 대상으로 설문을 실시하였고, 그중 442부를 회수하여 426 사례를 분석에 사용하였다. 연구결과, 유아교사의 직무스트레스는 교수효능감 및 조직몰입과 부적 상관관계를 보였으 며, 교수효능감은 조직몰입과 정적 상관관계를 보였다. 또한 유아교사의 교수효능감은 직무스트레스와 조직몰입 간의 관계에서 부분 매개효과를 가지는 것으로 나타났다. 본 연구는 유아교사의 소진을 설명하고자 직무스트레스를 바라보 는 방식에서 그 방향을 전환하여, 긍정적 관점인 조직몰입을 설명하기 위한 예측변인으로서 직무스트레스를 바라보았 다는 데 의의가 있으며, 교수효능감의 매개효과를 확인함으로써 환경적 개입에 대한 가능성을 제공하였다. The purpose of this study was to investigate the causal relationship among job stress, teaching efficacy belief, and organizational commitment for early childhood teachers. Besides, the current study examined the mediating effect of teaching efficacy belief on the relationship between job stress and organizational commitment. The data were gathered through the questionnaires from 500 kindergarten and nursery teachers who are located in D metropolitan city. Among them, the total of 426 subjects were used for analysis from recovered 442. The results indicated that job stress was negatively correlated with teaching efficacy belief and organizational commitment for early childhood teachers. Teaching efficacy belief significantly had a positive relation with organizational commitment. Moreover, teaching efficacy belief turned out to have a partial mediating effect on the relationship between job stress and organizational commitment. This study has its significance in that it looked at the job stress as a predictor variable to explain the organizational commitment, the positive viewpoint by turning away from the early childhood teachers’ burnout, and provided the potential for the environmental intervention by confirming the mediating effect of teaching efficacy belief.

대학생의 학업적 희망, 성취정서 및 심리적 안녕감의 구조적 관계

김영숙 ( Young Suk Kim ),조한익 ( Han Ik Cho ) 충남대학교 교육연구소 2016 교육연구논총 Vol.37 No.1

본 연구는 대학생의 학업적 희망, 성취정서 및 심리적 안녕감의 구조적 관계를 살펴보는데 목적이 있다. 연구문제는 첫째, 학업적 희망, 성취정서 및 심리적 안녕감의 구조적 관계는 어떠한가, 둘째, 학업적 희망과 심리적 안녕감의 관계에서 성취정서의 매개효과는 어떠한가 등이다. 연구대상은 대학생 387명으로 남학생은 143명, 여학생은 244명이다. 측정도구는 학업적 희망, 성취정서 및 심리적 안녕감 척도이다. 연구결과 학업적 희망은 정적정서에 정적인 영향을 미치고 있으며 부적정서에는 부적인 영향을 미치고 있었다. 정적정서는 심리적 안녕감에 정적인 영향을 미치고 있었고, 부적정서는 심리적 안녕감에 부적인 영향을 미치고 있었다. 학업적 희망은 심리적 안녕감에 직접적인 영향을 미치고 있지는 않지만 정적정서와 부적정서를 매개로 하여 심리적 안녕감에 영향을 미치고 있었다. 본 연구를 바탕으로 선행연구와의 관련성, 연구의 의의, 제한점 등을 제시하였다. The purpose of this study was to examine the relationship between academic hope, achievement emotions, and psychological well-being. Also, the study aimed to discover the mediation effect of achievement emotions on the relationship between academic hope and psychological well-being. The subjects were 387 college students, 143 male students and 244 female students. The instruments used in the study were academic hope, achievement emotions, and psychological well-being. Academic hope had a positive effect on positive emotions and psychological well-being, but a negative effect on negative emotions. Positive emotions mediated the relationship between academic hope and psychological well-being, and negative emotions also mediated the relationship between academic hope and psychological well-being. This, meant that academic hope had an indirect effect on psychological well-being via achievement emotions. Based on the relevance of prior researches, the significances and implications of this study were discussed.

일 지역 여대생의 유방자가검진에 대한 지식, 태도 및 실천의 관계

김영숙(Young-Suk Kim) 한국콘텐츠학회 2013 한국콘텐츠학회논문지 Vol.13 No.6

본 연구는 일 지역 여대생의 유방자가검진에 대한 지식, 태도 및 실천 정도를 파악하고 제 변수간의 상관관계를 확인하기 위하여 시도되었다. 연구대상자는 U시에 소재한 1개 대학교에 재학 중인 여대생 330명으로 설문 조사하였으며, 연구결과 지식 점수는 6.60점/17점으로 낮았고, 태도 점수는 42.34점/64점으로 중간보다 높게 나타났으며 실천 점수는 13.23점/24점으로 중간정도로 나타났다. 대상자의 제 특성에 따른 유방자가검진에 대한 지식 정도는 연령(t=11.013 p<.001), 학년(t=12.725, p<.001), 유방자가검진에 대해 들어 본 경험이 있는 경우(t=6.661, p<.001), 권유자가 있는 경우(t=3.426, p=.001), 교육을 받은 경험이 있는 경우(t=5.825, p<.001), 유방자가검진을 시행하는 경우(t=2.789, p=.005)에서 통계적으로 유의한 차이가 있었다. 대상자의 제 특성에 따른 유방자가검진에 대한 실천 정도는 유방자가검진에 대해 들어본 경험이 있는 경우(t=5.250, p<.001), 교육을 받은 경험이 있는 경우(t=4.493, p<.001), 앞으로 자가검진 계획이 있는 경우(F=3.910, p=.013)에서 통계적으로 유의한 차이가 있었다. 대상자의 유방자가검진에 대한 지식, 태도 및 실천과의 관계를 살펴본 결과 지식과 태도 정도의 관계는 미약한 순 상관관계를 보였고, 지식과 실천 정도의 관계는 약한 순 상관관계로 나타났다. 연구의 결과를 토대로 여대생의 유방자가검진 실천을 향상시킬 수 있는 효과적인 유방자가검진 교육방법 개발이 필요하다. Purpose: The study was to identify the relationships between knowledge, attitude and practice on breast self-examination among female university students. Methods: This descriptive study was conducted with a convenient sample of 330 female university students. Results: The mean score for knowledge of breast self-examination was 6.60/17 and attitude toward breast self-examination 42.34/64 and Practice level for breast self-examination was 13.23/24. The level of knowledge was differed significantly by Age(t=11.013 p<.001), Grade(t=12.725, p<.001), hearing experience of BSE(t=6.661, p<.001), experience of recommendation by others about BSE(t=3.426, p<.001), Educational experience of BSE(t=5.825, p<.001), experience of performance of BSE(t=2.789, p=.005). Practice level was differed significantly by hearing experience of BSE(t=5.250, p<.001), Educational experience of BSE(t=4.493, p<.001), Plan of BSE(F=3.910, p=.013). Slightly positive correlations were found between knowledge and attitude, knowledge and practice. Conclusion: The study suggested that we need to develop effective educational program for breast self examination to promote practice level of female students in university.