우리나라에 한파 내습시 동아시아 지역의 국지 2차 순환

김금란(Kum-Lan Kim),박순웅(Soon-Ung Park) 한국기상학회 1987 Asia-Pacific Journal of Atmospheric Sciences Vol.23 No.3

학교 급식에서의 중학생들의 식품 기호도 조사

김금란(Geum Ran Kim),김미정(Mi Jung Kim) 한국조리학회 2007 한국조리학회지 Vol.13 No.4

서울, 경기 일부지역 고등학생의 간식 섭취 실태와 일반사항과의 차이

김금란(Geum Ran Kim),김미정(Mi Jung Kim) 한국조리학회 2013 한국조리학회지 Vol.19 No.2

The purpose of this study is to investigate snacking behavior of high school students. The subjects were 1,587 students (684 male, 903 female) in Seoul and Paju. The highest number of eating snacks was ``once(39.9%)`` per day, and they preferred ``milk and cookies`` and ``fruit.`` For the result of reasons for choosing a snack, they chose ``what I want to have (59.6%)`` most and ``snacks don`t affect eating meals (48.0%).`` Also, compared with the ones with ``an elementary school diploma,`` the percentage of those with ``a middle school diploma`` was higher in ``having snacks once or three times`` according to father`s education level(p<0.05). In snack types and general characteristics, they chose ``milk and cookies`` when their expenses range ``under 50000 won`` and ``100,000 won`` and ``fruit`` when ``70,000won`` and ``over 100,000 won (p<0.05).`` In the reasons for choosing a snack, younger mothers(30-50ages) said ``what I want to have`` while elder mothers(□51ages) ``depending on my mood.`` Also, the respondents whose mothers had ``a high school diploma`` answered ’what I want to have`` the most (p<0.05). Especially, in case of effects after eating snack, they answered ``poor meals (35.5%)`` whose mother`s job was professional. These results suggest that the general characteristics of family environment may affect snacking behavior among high school students. They need a guideline to help select healthy snacks for desirable eating behavior.

창이자 추출물이 아토피 피부염 유발 생쥐의 비장 세포 Th17의 세포분화 억제에 따른 아토피 피부 상태에 미치는 영향

김금란(Kim, Kum-Lan),최태부(Choe, Tae-Boo) 한국생물공학회 2009 KSBB Journal Vol.24 No.4

아토피피부염 (AD)은 천식, 음식 알레르기, 비염 같은 전신아토피질환을 동반하는 만성재발성 피부염증질환이다. 아토피피부염과 관련된 IL-17의 임상적 역할은 다양한 조건에서 보고되고 있으며, 또한 건선 피부 상태에 깊숙이 관여하고 있다. IL-17은 각질세포 (keratinocytes)에서 과잉으로 생산되며, 아토피피부염의 말초임파구에서도 다량 생성 됨을 세포내염색을 통하여 확인된 바 있다. 본 연구에서는 창이자 추출물 (XS-E와 XS-FL)이 NC/Nga 생쥐의 CD4<SUP>+</SUP> T 세포에서 유도된 Th17 세포의 분화억제 및 IL-17의 생산량 감소 효과에 대한 실험을 하였다. 그 결과 XS-E와 XS-FL을 처리한 섬유아세포에서 세포독성은 나타나지 않았고, 4일간 XS-E와 XS-FL에 동시배양 한 CD4<SUP>+</SUP> T 세포 의 IL-17 생산량을 FACS로 분석한 결과 100 μg/mL XS-E 처리군의 IL-17 생산량은 32.3%로 대조군에 비하여 2배 이상의 감소를 나타내었으며, 20 μg/mL XS-30% AFL (acetone XS-FL) 처리군의 Th17 세포는 19.6%으로 대조군에 비하여 3.5배 억제되었다. 또한 real-time PCR을 이용하여 IL-17A와 IL-22 mRNA의 유전자 발현량을 비교 분석한 결과, IL-17A와 IL-22 mRNA의 유전자발현의 RQ값은 XS-E와 XS-30% AFL를 처리한 실험군이 대조군에 비하여 유의성 있는 감소를 나타내었다(p < 0.01, p < 0.001). ELISA로 측정한 IL-17A 생산량은 XS-E와 XS-30% AFL를 처리한 실험군이 대조군에 비하여 현저히 감소 (p < 0.05, p < 0.001)하였다. Th17 세포의 증식을 알아보기 위하여, rIL-6와 TGF-β로 분화시킨 Th17 세포를 CFSE로 표지한 후 rIL-23 처리를 하여 4일간 배양하여 증식을 유도시켰다. 대조군의 Th17 세포 분열은 4일 동안 4번에 걸쳐 비슷한 세포수의 증식이 일어나는 것을 CFSE를 통하여 확인하였고, XS-30% AFL 처리군은 CFSE의 형광 분포가 점점 감소하여 Th17 세포의 증식이 억제됨을 알 수 있었다. Xanthii fructus which is well known as “Chang-ihjah” in Korea is the dried fruit of Xanthium strumarium L. (or Xanthium sibiricum PATR. Ex WIDD., Asteraceae. XS). Water extract of this fruit has been used for treatment of various inflammatory diseases such as tympanitis, allergic rhinitis, or ozena as alternative therapy material usually by oral administration in far Eastern countries including Korea. In this study, the effect of XS extract (XS-E) or XS-30% acetone fraction layer (XS-30% AFL) on the differentiation of CD4<SUP>+</SUP> T cells isolated from NC/Nga mouse and the production of IL-17 was investigated. The experimental results showed that 100 μg/mL of XS-E could decrease the production of IL-17 by CD4<SUP>+</SUP> Th17 cells by 2 fold and only 20 μg/mL of XS-30% AFL could inhibit 3.5 fold. The amount of IL-17A and IL-22 mRNA determined by real-time PCR was decreased remarkably when XS-E or XS-30% AFL was treated on CD4<SUP>+</SUP> Th17 cells(p<0.01, p<0.001). The amount of IL-17A protein determined by ELISA was also decreased remarkably(p<0.05, p<0.001). To study the effect of XS-E or XS-30% AFL on the proliferation of Th17 cells, CD4+ T cells of a NC/Nga mouse was firstly differentiated by rIL-6/TGF-β and then stimulated by rIL-23. The control group of Th17 cells were doubled every each day, while those of XS-E or XS-30% AFL treated group were shown to be delayed remarkably by these extracts. In conclusion, XS can inhibit the differentiation of Th17 cells of NC/Nga mouse and the production of IL-17 successfully, which may be a beneficial result for the treatment of atopic skin dermatitis.

발관리가 소화기계 미치는 영향

김금란 ( Kum-lan Kim ),이주현 ( Ju-hyun Lee ),지주리 ( Ju-ree Ji ) 한국미용예술경영학회 2011 미용예술경영연구 Vol.5 No.3

The purpose of this study is to investigate effects of the foot reflexology therapy on digestive organs. For the purpose, this researcher applied the same therapy on those, whose digestive system was diagnosed dysfunctional when acupunctural points shown in their footprint were analyzed, over 5 sessions. Results of the study can be summarized as below. First, when effects of the foot reflexology therapy were compared between before and after its application, it was found that the same therapy were effective in improving all the organs as examined here. Second, when effects of the foot reflexology therapy on digestive organs were compared between before and after its application, it was found that the same therapy improved the function of liver by 2.1 times higher than when its was not applied. In conclusion, the foot reflexology therapy has good effects on all digestive organs of the abdomen.

센서 네트워크에서의 Rule-Base 기반 상황 인식 미들웨어

김금란(GeumLan Kim),김진아(J.A. Kim),김세웅(S.W. Kim),김창화(C.H. Kim),김상경(S.K. Kim),박찬정(C.J Park) 한국정보과학회 2006 한국정보과학회 학술발표논문집 Vol.33 No.2C

상황인식 처리기술은 사용자의 컨텍스트에 근거하여 사용자와 장치간의 상호 운용성을 지원해 줌으로써, 사용자로 하여금 정보 획득 및 실행을 보다 용이하게 하도록 해주는 기술이다. 여러 상황변화가 발생할 경우 이에 따라 서비스 전달 방식을 동적으로 적응시키기 위하여 상황에 대한 명시적인 요구사항을 정의하고 이 정의 된 상황을 각 노드에 전파하고 노드에 포함된 미들웨어는 전파된 상황에 적합한 센싱된 정보를 분석하여 특정한 상황의 발생과 이에 따른 액션을 수행하며 또한 센서에서 취득한 컨텍스트로 부터 통합된, 추론된 컨텍스트를 생성한다. 본 논문에서는 센서로부터 다양한 타입의 컨텍스트를 처리 할 수 있는 미들웨어를 제안한다. 이 미들웨어는 변화하는 주변 환경에서 센서로부터 센싱된 컨텍스트 뿐 아니라 통합된, 추론된 컨텍스트를 생성할 수 있도록 설계 되었다. 제안한 상황인식 미들웨어를 기반으로 사용자 질의 요청과 이벤트 상황 질의를 설계하였으며, 이벤트 상황 질의의 추론 DB를 명시하기 위하여 Clips 언어를 사용하였다.

TAT(주제통각검사)에서 일러스트레이션 기능의 코드분석

김금란(Kim Geum-Ran),홍찬석(Hong Chan-Seok),정성환(Jung Sung-Hwan) 한국디자인학회 2002 디자인학연구 Vol.- No.46

XS-E가 아토피피부염이 유발된 NC/Nga Mice의 피부상태에 미치는 영향

김금란(Kum-Lan Kim) 한국생물공학회 2014 KSBB Journal Vol.29 No.4

This study reports significant improvement of atopic dermatitis condition as a result of experiment using Xanthium strumarium L. extract (XS-E) at the dorsal skin of induced atopic dermatitis Nc/Nga mice. Skin clinical score has decreased (2.75±0.85, *p<0.05), showing visible change of skin condition. IgE (***p<0.001) and IgG1 (2522.00±32.80, ***p<0.001) in plasma also decreased significantly. mRNA (gene expression) level increased (RQ=2.75±0.10, ***p<0.001) within skin tissue of CD4+CD25+Foxp3+ Treg cell that’s activated by XS-E dosage, thereby discovering that there is an effect of suppressing proliferation and viability of Th2 cell, eosinophils, mast cell and inflammatory cell. Upon examining cells permeated with H&E and toluidine blue staining technique, thickness of epidermis and mast cell’s permeation decreased, and the result of examining the distribution of CCR 3+ eosinophils within ALN showed that it’s level fell down to that of wild type (normal group, NC/Nga-WT). By such results, it is suggested that XS-E is highly effective on atopic dermatitis, and it is considered that continued quantitative research and case study of clinical research such as effect of cell number in individual tissues or change of total cell number are necessary.

미용분야의 직무특성이 미용전문가의 직무만족에 미치는 영향에 관한 연구

김금란 ( Kum Lan Kim ),이정순 ( Jung Soon Lee ),최태부 ( Tae Boo Choe ) 한국미용학회 2009 한국미용학회지 Vol.15 No.2

The purpose of this research was to investigate the effect of job characteristics in various fields on beauty professional`s job. The subjects used in this study consisted of 205 beauty professionals with the different jobs: 50 make-up artists, 50 hair designers, 51 estheticians, and 54 nail artists. Job satisfaction contained overall job satisfaction and five facts satisfaction (work-itself, pay, promotion, co-worker, supervisor). Multiple regression analysis used to verify the effect of five job characteristics (Variety, Identity, Significance, Autonomy, Feedback) on overall job satisfaction. Data collected from subjects were processed by SPSS computer package program. The results were as below: 1. Overall job satisfaction was significantly different from working area of beauty advisor. Nail artists were more satisfied with their jobs than other cosmetic artists. 2. Out of five satisfaction, one factors (Work-itself) was significantly different from working area of beauty advisors. 3. As the result of correlation analysis to examine relationship between job satisfaction and individual characteristic data, The length of beauty advisor`s service was significantly correlated with overall job satisfaction. 4. Two factors among five facet satisfactions (Work-itself, Supervisor) significantly contributed to the overall job satisfaction. β coefficients of two factors were 0.550, 0.130. 5. Two factors among five core dimensions (Identity, Variety) significantly contributed to the overall job satisfaction. β coefficients of two factors were 0.360 and 0.155. In summarizing the results of this study, out of five facet satisfaction, one factor (work-itself) predicted and explained the overall job satisfaction of beauty professionals meaningfully. Variety factor among five core dimensions (significance, variety, autonomy, identity, feedback) significantly contributed to the job satisfaction.

피부관리방법에 따른 안면 피부상태의 차이

김금란 ( Kum Lan Kim ),이유미 ( You Mi Lee ),장순남 ( Soon Nam Jang ),이재남 ( Jae Nam Lee ),최태부 ( Tae Boo Choe ) 한국미용학회 2010 한국미용학회지 Vol.16 No.3

The purpose of this study was to examine the relationship between the facial treatment methods (cleansing, exfoliation, massage, pack/mask, use of cosmetics) and skin conditions of face(pores, pigmentation, wrinkles, skin color, erythema). First of all, facial treatment index was constructed by using a questionnaire that surveyed facial treatment methods of participants. Skin conditions of face were measured by using ROBO SKIN ANALYZER (CS50). The data were collected and measured from 345 female. In order to identify actual conditions of facial treatment, facial treatment index was analyzed. Facial treatment index of participants was cleansing (15.96), use of cosmetics (14.42), manual technique (12.08), exfoliation (11.36), pack/mask (8.54). The participants were divided according to facial treatment style. Facial treatment index of special treatment group (70.96) was higher than self treatment group (58.99). It was investigated the relationship facial treatment index and skin condition of face according to facial treatment group. Special treatment group showed significantly greater improvement in wrinkles. It was discussed various relations between facial treatment index and skin condition of face. The differences of facial treatment index according to skin condition of face were analyzed. Results showed that participants didn`t use facial treatment method suitable to one`s facial skin condition.