WWW에 기반한 부동산 거래 정보 관리 시스템 설계 및 구현

권석형,김명선,김양희,정창성 한국공간정보학회 1996 한국공간정보학회지 Vol.4 No.1

부동산 거래 관리 시스템이란 부동산 거래 관리 활동과 관련된 등록, 검색, 상담 및 부동산에 대한 이력 관리와 분석을 목적으로 하는 시스템이다. 거래 상담 및 분석 과정에서 부동산에 대한 지형 정보 서비스가 지대한 영향을 미친다. 본 시스템은 지도 정보 및 비디오나 사진등과 같은 영상 정보를 포괄하는 지형 정보 서비스를 제공함으로써, 원격지 거래자들간의 상담 및 관리/분석 활동이 원활히 이루어질 수 있도록 설계/구현되었다. 또한, WWW를 통해 이같은 지형 정보 서비스를 제공함으로써 사용자들이 별도의 클라이언트 에뮬레이터 없이 다양한 멀티미디어 서비스를 받을 수 있도록 설계/구현 되었다. Realty Trade Information Hanagement System(RTIMS) is intended to provide the services relat¬ed to realty business activity such as registration, search, negotiation, and information analysis. Introduction of the geographic information processing concept into the system has a great effect on the overall service processes of the realty business. This system is designed and implemented for remote users to easily get the informations about the target realty and to achieve a proper negotiation, by offering the various kinds of geographic informations including map, moving picture, photo, and so on. Futher, users can access RTIMS through WWW(World Wide Web) without additional client emulator.

In Order for FSBH to Take a Leap Forward as an International Academic Journal

권석형 건강기능식품미래포럼 2024 건강기능식품미래포럼 학술지 Vol.4 No.1

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버섯 균사체에 의한 암세포 성장억제 효과

권석형 ( Suk Hyung Kwon ),김춘년 ( Choon Nyeon Kim ),김철용 ( Chul Yong Kim ),권석태 ( Suk Tae Kwon ),박기문 ( Ki Moon Park ),황보식 ( Sik Hwangbo ) 한국식품영양학회 2003 韓國食品營養學會誌 Vol.16 No.1

버섯 균사체로부터 분리한 단백다당체의 Th1 cell 증식효과 및 각종 암세포에 대한 세포독성을 조사하였다. 단백다당체 시료는 영지버섯, 아가리쿠스, 표고버섯, 운지버섯, 그리고 상황버섯을 100℃에서 3시간 열수 수출하는 방법으로 조제하였다. Th1 cell의 세포 증식을 조사한 결과, 10mg/ml 농도에서 모든 시료가 40% 이상 억제하는 효과가 있는 것으로 나타났다 7종류의 암세포를 이용한 암세포 생존율을 조사한 결과, 1mg/ml 농도에서 P388D1와 L1210에서 아가리쿠스는 2.4% 와 39.7%, 표고버섯은 48.4%와 52.5% 의 생존율을 보였다. Sarcoma 180 으로 복수암을 유발시킨 마우스에게 아가리쿠스와 표고버섯으로부터 추출한 단백다당체를 섭취시킬 경우 생존율이 27 ~ 40%까지 유의적으로 증가하는 것으로 나타났다. The purpose of this study is to observe the effect of protein-bound polysaccharide (PBP) on proliferation of Th1 cells and cytotoxicity of cancer cell. Mushrooms (Ganoderma lucidum, Agaricus blazei, Lentinus edodes, Coriolus versicolor and Phellinus linteus) were fractionated by 100℃ hot water for 3hr. PBP was stimulated and proliferated Th1 cells most at 10 mg/ml concentration and the percentage of cell proliferation was 40%. It was estimated cytotoxicity of PBP against 7 kinds of cancer cell lines. Antitumor activities of Agaricus blazei against P388D1 and L1210 (tumor cell lines) were 2.4% and 39.7% survival rate, and Lentinus edodes was 48.4$ and 52.5% survival rate, respectively. PBP mixtures of Agaricus and Lentinus edodes prolonged (27 ~ 40%) significantly the survival rate of mice intraperitoneally implanted with sarcoma 180.

동아의 생리활성

홍석산,권석형,Hong, Seok-San,Gwon, Seok-Hyeong 한국식품연구원 1998 食品技術 Vol.11 No.1

OQL/Geo : 지리 정보 시스템을 위한 객체지향 공간 질의어

김양희,김명선,권석형,정창성 한국공간정보학회 1995 한국공간정보학회지 Vol.3 No.2

데이타 모델(data model)이란 실세계에 대한 공간 및 비공간적 특성(feature)을 추상화한 시스템 모델이다. 각 시스템들을 고유한 데이타 모델을 통해 외부 세계에 대한 내부 표현및 외부 세계와의 접속관계에 대한 틀(framework)을 정의하게 되며, 공간 질의어는 지리 정보시스템에서 정의하고 있는 외부 세계화의 접속 관계를 우한 효과적인 틀의 하나이다. 기존의 지리 정보 시스템에서는 관계형 데이타 모델에 기반한 공간 데이타 모델들이 주로 사용되었으므로 데이타 추상화(abstraction)및 상속 (inheritance)을 통한 복합 객체의 표현에 문제점이 있었다. 본 논문에서는 ODMG의 객체 모델을 기반으로 평면 위상 모델 (planar topological model)을 수용하여 객체지향 데이타 모델인 위상 객체 모델(Topological Object Model : TOM)을 제안하고, 이를 기반으로 객체지향 공간 질의어인 OQL/Geo을 설계하였다. OQL/Geo은 ODMG에 의해 개발된 질의어인 OQL을 기반으로 하여 위상 객체 모델을 효과적으로 표현할 수 있도록 확장하였으며, 기하연산, 위상연산및 가시연산등의 풍부한 연산자들을 제공하고 있으며, 복잡한 공간 분석에 대한 요구 뿐 아니라 질의 결과에 대한 출력 형식도 다양하게 표현할 수 있도록 하였다. The data model is a system model which abstracts the spatial and nonspatial fea￢tures of the real world. A system defines through its data model a framework for the inner rep￢resentation of and connections with the outside world. The spatial query language is one of the most efficent framework for defining connection with outside world in the GIS. Existing GIS uses a spatial data model based on relational data model. Therefore, it has some difficulties in data abstraction and representing complex objects through inheritance. In this paper, we pro-pose an object oriented data model-Topological Object Model(TOM). TOM combines object model in ODMG and the planer topological object. Based on this model, we present an object-oriented spatial query language-OQL/Geo. OQL/Geo extends OQL in ODMG and represents TOM effectively. It also provides several operators such as geometric, topological and visible ope-rators. Moreover, it represents with diverse flexivility the request for complex spatial analysis and presentation of query results.

FlexPro MD, a Mixture of Krill Oil, Astaxanthin, and Hyaluronic Acid, Suppresses Lipopolysaccharide-Induced Inflammatory Cytokine Production Through Inhibition of NF-κB

박두리,고려진,권석형,민복기,윤승호,김많흔,이수영 한국식품영양과학회 2016 Journal of medicinal food Vol.19 No.12

FlexPro MD® (FP-MD), a novel multi-ingredient dietary supplement formulation, has been demonstrated to relieve knee joint pain in humans. However, the mechanisms of action responsible for the activity of FP-MD have not been elucidated. In this study, we show the anti-inflammatory effects of FP-MD in RAW264.7 macrophage cells and mice challenged with lipopolysaccharide (LPS). FP-MD significantly inhibited the mRNA levels of pro-inflammatory cytokines, including interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and IL-1β. In contrast, it elevated the mRNA levels of anti-inflammatory cytokine IL-10 in LPS-stimulated RAW264.7 cells. FP-MD markedly reduced LPS-induced phosphorylation levels of nuclear factor-κB (NF-κB) p65 and inhibitor of κB-α (IκB-α). Importantly, the anti-inflammatory effects of FP-MD were demonstrated in mice with LPS-induced inflammatory arthritis in which FP-MD significantly reduced the expression levels of pro-inflammatory cytokines and inflammatory markers. Thus, this study suggests that FP-MD has anti-inflammatory effects by inhibiting NF-κB that may offer a molecular basis for its pain relief property.

Polymer-based Sustained Release Tablets of Vitamin C Using Hydroxypropyl Methylcellulose and Ethylcellulose and Their Dissolution Tolerances

김현균,신기형,구윤태,김창현,권석형,정재철,최영욱 한국고분자학회 2022 폴리머 Vol.46 No.2

In this study, we developed sustained release tablets of vitamin C (ascorbic acid, AA) to establish dissolution tolerances and recommend appropriate formulations. We fabricated hydroxypropyl methylcellulose (HPMC) matrix tablets (HTs) and ethylcellulose (EC)-pelletized tablets (ETs) using direct compression and/or fluidized coating. Along with three commercially available products for reference, we acquired the AA dissolution profiles of the prepared samples in 5% metaphosphoric acid aqueous solution to prevent the degradation of AA. We then compared the release patterns using the similarity factor (f2). The selected two formulations (HT7 and ET1) showed drug release within the limit of ±15% of the reference curve, followed by the Korsmeyer-Peppas model. We found that the range of dissolution tolerance for the sustained release formulation was 15-40% (1 h), 25-70% (3 h), 50-90% (5 h), and ≥80% (8 h)

회화나무 열매의 고지혈증 개선 효능

최선은,심재걸,오명환,권석형,이민원 한국생약학회 2009 생약학회지 Vol.40 No.3

Anti-hyperlipidemic effect of Sophorae Fructus in male Spague-Dawley rats induced by high-rich diet were studied. Oral administration of Sophorae Fructus extract significantly decreased serum total cholesterol (TC), LDL-cholesterol, triglyceride (TG), GOT and GPT levels, and incresed serum HDL-cholesterol level and also decreased the level of liver TC, TG, GOT and GPT. These results suggest that Sophorae Fructus extract is effective for the hyperlipidemia.

유산균을 안정화시킨 마이크로캅셀의 제조 및 평가

이영재,최영욱,전홍렬,박동우,권석형 한국약제학회 2000 Journal of Pharmaceutical Investigation Vol.30 No.1

A new technique has been developed for the preparation of Lactobacillus microcapsules to enhance the stability against high temperature, humidity, gastric acid and bile acid. Employing fluidized bed coating, primary sub-coating was processed in non-organic solvent system, so that Lactobacillus did not directly contact with organic solvent. Secondary enteric-coating was processed in organic solvent with low temperature (below 33℃) technique, which minimized the heat labilability of Lactobacillus. Survival rate of Lactobacillus within microcapsule was not less than 95% and acid tolerance was above 30% in the artificial gastric acid. Further more it was dissolved in the artificial intestine juice within 2∼3 hr. Average size of Lactobacillus microcapsules was 450 ㎛(25-50 mesh) and its viability was above 90% in the direct tableting.

Anti-oxidative Phenolic Compounds from Sophorae Fructus

김현정,김민기,심재걸,염승환,권석형,이민원 한국생약학회 2004 Natural Product Sciences Vol.10 No.6

Four isoflavonoids and three flavonoids, and a gallotannin were isolated from the fruits of Sophora japonica (Leguminosae). Their structures were identified as genistein (1), sophoricoside (2), genistein-4'-O--L-rhamnopyranoside (3), $genistein-4'-O-{\alpha}-L-rhamnopyranosly-(1{\rightarrow}2)-{\beta}-D-glucopyranoside$ (4), $kaempferol-3-O-{\alpha}-D-sophoroside$ (5), $kaempferol-3-O-{\beta}-D-glucopyranosyl-(1{\rightarrow}2)-{\alpha}-L-rhamnopyranosly-(1{\rightarrow}6)-{\beta}-D-glucopyranoside$ (6), rutin (7) and gallic acid $4-O-{\beta}-D-(6'-O-galloyl)-glucopyranoside$ (8) by chemical and spectroscopic analysis and comparisons with previously reported spectral data. Compounds 3 and 8 were isolated for the first time from this plant. Anti-oxidative activity was evaluated for the isolated compounds. 8 exhibited potent anti-oxidative activity against the radical scavenging ability of DPPH with the IC50 value of $17.1\;{\mu}g/ml$.