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      • 犀角 Rhinocerotis Cornu이 家兎血淸中 Cholesterol Triglyceride 含量變化에 미치는 影響

        姜孝信,具本情 中央醫學社 1972 中央醫學 Vol.23 No.3

        The effect of the Rhinocerotic Cornuc extract (R.C.) on the amount of total cholesterol and triglycerides in serum from rabbit were observed. The preparations were extracted by methanol; an extracted samples were orally administrated to the rabbits fasted for three days. After three days starvation, the amounts of total cholesterol and triglycerides in serum of the rabbit were markedly increased. The increased amounts of total cholesterol and triglyceides were gradually de-creased by administration of the extracted samples and were returned to the control levels after three days. According to the above results, it would be concluded that R.C. influences for the recovery of the increased amounts of total cholesterol and triglycerides by abnormal metabolism to normal on rabbit.

      • KCI등재

        분노 정서조절 과정에서 나타나는 연령차 및 개인차: 노인 집단과 대학생 집단 비교

        강효신,권정혜 한국심리학회 산하 한국발달심리학회 2019 한국심리학회지 발달 Vol.32 No.4

        This study was designed to examine both age-related and individual differences in real emotion regulation after anger mood induction. In this study, older (n=50) and young adults (n=50) watched two negative films and rated their mood using a visual analogue scale every 2 min for approximately 25 min. Results revealed that older adults were more likely than younger adults to quickly regulate their emotions. In order to identify individual differences in emotion regulation, a growth mixture modeling was performed on the mood ratings. Growth mixture modeling on older adults group revealed three latent subgroups of mood-change trajectories: positive-maintain group, negative-decrease group, and neutral-increase group. There was a significant group difference for negative emotional experience and anxiety level in older adults, whereas there was a significant group difference for positive emotional experience and emotion regulation strategies in younger adults. This suggests that considering not only age differences but also individual differences in emotion regulation is very important to understand emotional characteristics in old age. 본 연구는 분노 정서를 경험할 때 정서조절 과정에서 나타나는 연령에 따른 차이와 개인차를 살펴보기 위해 수행되었다. 노인 집단 50명과 대학생 집단 50명을 대상으로 부정 정서를 유도하는 두 편의 동영상을 시청한 후 2분 간격으로 자신의 기분 상태를 0-100점 범위의 시각 아날로그 척도에 표시하도록 하였다. 대략 25분간 총 13번의 기분 상태를 평가한 결과, 노인은 대학생에 비해 부정 정서로부터 더 빠르게 긍정적인 기분으로 변화하는 경향성을 보여 정서조절에서의 연령차를 확인할 수 있었다. 다음으로 정서조절 과정에서 개인차가 나타나는지 검증하기 위해 노인과 대학생 참가자의 기분평가를 토대로 각각 성장혼합모형을 실시하였다. 분석 결과 노인은 긍정-유지, 부정-감소, 그리고 중립-증가 집단, 대학생은 긍정-유지, 부정-유지, 그리고 중립-증가 집단으로 분류되어, 노인과 대학생 모두 각각 세 개의 잠재집단이 도출되었다. 집단에 따른 특성 차이를 분석하였을 때, 노인 집단은 부정 정서 경험과 불안 수준에서, 대학생 집단은 긍정 정서 경험과 정서조절 전략에서 유의한 차이가 나타났다. 이러한 결과는 정서조절에서 연령차를 보이며, 노인 집단 내에서도 개인차 특성이 정서조절 능력에 영향을 미친다는 것을 확인하였다는 점에서 의의가 있다.

      • KCI등재

        Factors Associated with Caregiver Burden in Patients with Alzheimer’s Disease

        강효신,김도관,Woojae Myung,Duk L. Na,Seong Yoon Kim,Jae Hong Lee,Seol-Heui Han,최성혜,김상윤,김선우 대한신경정신의학회 2014 PSYCHIATRY INVESTIGATION Vol.11 No.2

        Objective Caregivers for patients with Alzheimer’s disease (AD) suffer from psychological and financial burdens. However, the results of the relationship between burden and cognitive function, performance of activities of daily living, and depressive symptoms have remained inconsistent. Therefore, the aim of this study was to examine which factors are more significant predictors of heightened burden, cognitive impairment or functional decline, besides neuropsychiatric symptoms. Methods A cross-sectional study was conducted in a sample comprised of 1,164 pairs of patients with AD and caregivers from the Clinical Research of Dementia of South Korea study cohorts. The cognitive function of each sub-domain, functional impairments, depressive symptoms, and caregiver burden were assessed using the dementia version of Seoul Neuropsychological Screening Battery (SNSB-D), Barthel Index for Daily Living Activities (ADL), Seoul-Instrumental Activities of Daily Living (S-IADL), the Clinical Dementia Rating Sum of Box (CDR-SB), the Global Deterioration Scale (GDS), the Korean version of the Neuropsychiatric Inventory (K-NPI), and the 15-item Geriatric Depression Scale. Results We found that higher severity (higher CDR-SB and GDS scores) and more functional impairment (lower ADL and higher SIADL scores) were significantly associated with higher caregiver burden. In addition, depressive symptoms of patients (higher Geriatric Depression Scale scores) were associated with higher caregiver burden. Conclusion Therefore, interventions to help maintain activities of daily living in patients with AD may alleviate caregiver burden and improve caregiver well-being.

      • SCIESCOPUSKCI등재

        식이성 인삼이 Alcoholic Rat 의 간 Vitamin A 와 혈액내 성분에 미치는 영향

        강효신,조용호,신상주 ( Hyo Shin Kang,Yong Ho Cho,Sang Jou Shinn ) 생화학분자생물학회 1975 BMB Reports Vol.8 No.3

        Preformed hepatic eitamin A conent was increased with the augmentation of dietary protein level in a significant rate but the reverse was true in the case of dietary ginseng treatment to alcoholic rats. Neither dietary protein level nor ginseng feeding changed the amount of serum protein, indicating that 14 percent of dietary protein satisfy the requirement of this nutrient in ethanol treated rats. Both the increase in protein level of diet and the feeding of ginseng tended to decrease blood cholesterol level in rats treated with ethanol for a period of four weeks. No definite changes were brought about on the blood glucose content either by an increase in dietary protein level or by the dietary ginseng treatment.

      • SCIESCOPUSKCI등재

        식이성 인삼이 백서의 간 기능 저항 예방에 미치는 영향

        강효신,조용호,신상주 ( Hyo Shin Kang,Yong Ho Cho,Sang Jou Shinn ) 생화학분자생물학회 1975 BMB Reports Vol.8 No.3

        The enzymatic activity of serum glutamic-pyruvic transaminase is influenced by the addition of ginseng into diet at one percent level and the difference between the treatments is significant. at the same level of dietary protein, ginseng decreases slightly this enzymatic activity. Serum glutamic-oxaloacetic transaminase activity is highly influenced by dietary ginseng in rats administered with ethanol. The feeding of this plant to rats maintained with a same level of dietary protein significantly reduced its enzymatic activity. A similar tendency is also observed with the increase of dietary protein level. Both the addition of dietary ginseng and the increase in dietary protein level exert a profound influence on the enzymatic activity of serum lactic dehydrogenase, indicating that ginseng really hase protective effect on liver from deterioration caused by a prolonged and repeated ethanol ingestion.

      • KCI등재

        얼굴 정서 자극에 대한 정서가 및 각성가 평가에서의 연령차 연구

        강효신,권정혜 한국인지및생물심리학회 2019 한국심리학회지 인지 및 생물 Vol.31 No.2

        This study was designed to investigate the age-related differences in valence and arousal ratings for stimulus materials. In this study, older (n=50) and young adults (n=50) rated 54 emotional faces in terms of valence and arousal using a 7-point scale. Older adults reported happy and neutral faces as being more positive and angry faces as being more negative than young adults did. A similar pattern was evident for arousal. Older adults rated negative and neutral faces as being more arousing than young adults did. This suggests that the older adults have a tendency to respond to emotional faces more extremely. Furthermore, whereas older adults showed a linear association between valence and arousal, young adults showed a U-shaped function. Clinical implications and limitations of the current findings are discussed. 본 연구는 얼굴 정서 자극 평가에서 연령에 따른 차이를 보이는지 살펴보기 위해 수행되었다. 노인과 대학생 집단 각각 50명을 대상으로 얼굴 정서 자극에 대한 정서가와 각성가를 각각 7점 척도로 평가하도록 한 결과, 노인은 대학생에 비해 기쁨과 중립 얼굴 자극은 더 긍정적인 것으로, 분노 얼굴 자극은 더 부정적인 것으로 보고하였다. 각성가 평가에서도 이와 유사하게 노인은 대학생보다 좀 더 극단에 치우치는 경향을 보였다. 또한 정서가와 각성가의 관계를 살펴보았을 때 노인은 두 차원이 선형관계를 보인 반면, 대학생은 U자형에 더 가까운 관계를 보여 연령에 따른 차이가 확인되었다. 이러한 결과는 정서 자극을 활용한 연구를 실시할 때 정서 자극 평가에서의 연령차를 고려하는 것이 매우 중요함을 시사한다.

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