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      • KCI등재

        중등 여성체육교사의 스포츠 리터러시 탐색

        우소연,조미혜 한국여성체육학회 2023 한국여성체육학회지 Vol.37 No.3

        The purpose of this study was to investigate the factors, components, and characteristics of sports literacy of middle school female physical education teachers. The collected data were analyzed by inductive categorical analysis and the results were derived from a total of seven major factors, including five factors common to beginner and experienced teachers and two factors that differ according to career. The common factors were ‘sociality’, ‘knowledge and understanding’, ‘self-respect’, ‘teacher professionalism’, ‘attitude and value’, and the factors of career difference were classified into ‘skillfulness’ and ‘adaptability’, and 11 and 2 detailed components were derived, respectively. In addition, the common characteristics of sports literacy of secondary female physical education teachers were ‘surviving in the ecosystem of school’, ‘constant trimming’, ‘burning firewood in the mind’, ‘alchemist in class’, ‘equal gender awareness’, and personal characteristics were ‘self-esteem as an educator’, ‘self-esteem as a learner’, ‘identity as an educator and a sense of calling’.The results of this study will be helpful for female physical education teachers to perform their role as educators more effectively.

      • KCI등재

        Angiostatin Works as Immune Modulatory Molecules via Inhibition of Neutrophil Activation and Migration

        우소연 대한미생물학회 2014 Journal of Bacteriology and Virology Vol.44 No.1

        Angiostatin is derived from enzymatic degradation of plasminogen and it has endogenous anti-angiogenic properties. Although tumor cells, macrophages, platelets, and neutrophils generate high amount of angiostatin, its expression is increased in inflammatory conditions. Moreover, angiostatin binds to integrin αvβ3, ATP synthase, and angiomotin, which expressed on neutrophils. Activated neutrophils are essential to innate immune response, but also cause tissue damage through production of reactive oxygen species (ROS) and increase lifespan. In this article, it suggests several mechanism of angiostatin as immune regulator for neutrophils in inflammatory conditions; complex with integrin αvβ3 and F1F0 ATP synthase on lipid raft, attenuate polarization, and ROS production. These data provide possible exploit of double-edged role of neutrophils in acute inflammatory pathologies to preserve beneficial effect and minimize tissue damage.

      • KCI등재후보

        Oral Tolerance Increased the Proportion of CD8+ T Cells in Mouse Intestinal Lamina Propria

        우소연,조경아,차제은 대한면역학회 2008 Immune Network Vol.8 No.2

        Background: Oral tolerance is defined by the inhibition of immune responsiveness to a protein previously exposed via the oral route. Protein antigens exposed via the oral route can be absorbed through the mucosal surfaces of the gastrointestinal tract and can make physical contact with immune cells residing in the intestinal lamina propria (LP). However, the mechanisms of oral tolerance and immune regulation in the intestines currently remain to be clearly elucidated. Methods: In order to determine the effect of oral protein antigen intake (ovalbumin, OVA) on the intestinal LP, we assessed the expression profile of the T cell receptor and the co-receptors on the cells from the intestines of the tolerant and immune mouse groups. Results: We determined that the proportion of OVA-specific B cells and γδ T cells had decreased, but the CD8αβ and CD8αα T cells were increased in the LP from the tolerant group. The proportion of CD8+ T cells in the spleen did not evidence any significant differences between treatment groups. Conclusion: These results indicate that CD8+ T cells in the intestinal LP may perform a regulatory role following antigen challenge via the oral route.

      • KCI등재

        Neutrophils in Immunity

        우소연 대한미생물학회 2012 Journal of Bacteriology and Virology Vol.42 No.2

        Neutrophils are the most abundant white blood cells in the peripheral blood and have long been recognized as the major phagocytes in acute infection by destroying extracellular pathogens. Although research on neutrophils hampered by intractability in the experiments, the newly discovered effector functions of neutrophils includes granular proteins,and cytokines, extracellular traps. With all effector mechanism neutrophils play a critical role in the pathogenesis of acute and chronic infection, autoimmunity and cancer.

      • KCI등재

        ATLAS V2.0 데이터에서 의료영상 분할 모델 성능 비교

        우소연,구영현,유성준 한국방송∙미디어공학회 2023 방송공학회논문지 Vol.28 No.3

        의료영상 공개 데이터는 수집에 한계가 있어 데이터셋의 양이 부족하다는 문제점이 있다. 때문에 기존 연구들은 공개 데이터셋에과적합 되었을 우려가 있다. 본 논문은 실험을 통해 8개의 (Unet, X-Net, HarDNet, SegNet, PSPNet, SwinUnet, 3D-ResU-Net,UNETR) 의료영상 분할 모델의 성능을 비교함으로써 기존 모델의 성능을 재검증하고자 한다. 뇌졸중 진단 공개 데이터 셋인Anatomical Tracings of Lesions After Stroke(ATLAS) V1.2과 ATLAS V2.0에서 모델들의 성능 비교 실험을 진행한다. 실험결과 대부분 모델은 V1.2과 V2.0에서 성능이 비슷한 결과를 보였다. 하지만 X-net과 3D-ResU-Net는 V1.2 데이터셋에서 더 높은 성능을 기록했다. 이러한 결과는 해당 모델들이 V1.2에 과적합 되었을 것으로 해석할 수 있다

      • KCI등재

        목격자의 범인식별 절차에서 식별 전 지시와 순차적 제시방식 유형에 따른 식별 정확성

        우소연,조은경 한국사회및성격심리학회 2012 한국심리학회지 사회 및 성격 Vol.26 No.4

        Eyewitness testimony often plays an important role in criminal justice system. As evidenced by some documented cases of wrongful convictions based on eyewitness identification errors, there are a serious eyewitness identification problems that need to be corrected. Eyewitness may identify a culprit through a series of identification procedures, and most research has suggested that the sequential presentation of photospread that shows a witness limeup members at a time is a better method than simultaneous presentation of photospread in which all lineup members are presented at the same time. However, sequential lineup may tend to commit more false rejection errors in culprit present condition, whereas less false identification error in culprit absent condition. The purpose of this study is to clarify false rejection in sequential lineup procedure and to identify effects of the factors on witness identification accuracy. Also, we studied the effects of lineup instruction by sequential presentation type on witness identification accuracy. In this study 180 undergraduate students participated in a 3(types of sequential lineup: immediate decision with stopping rule, immediate decision without stopping rule, final decision without stopping rule)✕2(lineup instructions: biased, unbiased)✕2(culprit: present, absent) between subject experiment. The experiment procedure is that experimenter show a subject criminal video clip and ask the subject to perform identification procedure. The results of this study present that sequential procedure in which eyewitnesses are allowed to make a final decision without stopping rule could reduce false rejection errors,while maintaining high identification accuracy. Limitations and implications of this study were discussed. 본 연구의 목적은 순차적 제시방식에서 식별률을 낮추는 요인들이 무엇인지 살펴보고, 이 요인들의 유무에 따라서 목격자의 식별 정확성에 차이가 나타나는지를 확인하고자 하였다. 아울러 식별절차를 수행하기 전 식별 전 지시에 따라서도 순차적 제시방식 유형의 식별 정확성에 차이가 나타나는지를 확인하고자 하였다. 본 연구의 실험은 피험자간 설계로 순차적 제시방식의 즉시 판단규칙과 정지 규칙의 유무, 식별 전 지시의 편향 지시와 비편향 지시, 사진열 중 실제 범인의 존재 여부에 따라서 조건별로 할당하였다. 실험 참가자들은 범죄 사건을 촬영한 동영상을 시청한 후 범인식별 절차를 거쳤다. 연구 결과는 사진열에 실제 범인이 존재하는 조건에서 즉시 판단을 하지 않고 정지규칙을 적용하지 않는 조건이 두 규칙을 적용한 다른 조건보다 더 높은 식별 정확성을 나타내었다. 실제 범인이 존재하지 않는 조건에서는 순차적 제시방식에 따른 식별 정확성의 차이가 없었다. 식별 전 지시에 따라 순차적 제시방식의 식별 정확성에는 차이가 없는 것으로 나타났다. 연구 결과를 바탕으로 본 연구는 높은 식별 정확성을 유지하면서 오기각률을 감소시킬 수 있는 대안적인 라인업의 필요성을 제언하였고, 연구의 의의와 목격자 식별 절차와 관련한 정책적 함의는 이후 논의하였다.

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