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      • KCI등재

        기능성 유지자원으로서의 들깨(Perilla frutescens var. frutescens)의 이용과 가치

        최용순 한국자원식물학회 2015 한국자원식물학회지 Vol.28 No.1

        The Korean daily intake of vegetable oils has increased about 2.5-fold from 17 g/day to 46 g/day for the lastseveral decades. Perilla (Perilla frutescens var. frutescens) has been cultivated in Korea for a long time as a dietary oil seedwhich has the highest content of α-linolenic acid, accounting for nearly 60%. It is known that the main role of ALA is as aprecursor to the longer-chain ω-3, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), the metabolic productsof α-linolenic acid (ALA, ω-3). Dietary ω-3 fatty acids reduce inflammation and the risk of chronic diseases such as heartdisease, cancer, and arthritis, but they also may act as functional components for cognitive and behavioral function. Thus, α-linolenic acid is one of the essential nutrients in modern dietary patterns in which much linoleic acid is consumed. Nevertheless, perilla oil, rich in α-linolenic acid, can be easily oxidized, giving rise to controversies with respect to shelf life,the deterioration of the product’s commercial value, and further related toxicity. Recent research using genetic modificationshas tried to develop new plant oil seeds that balance the ratio of ω-6/ω-3 fatty acids. Such trials could be a strategy forimproving an easily oxidizable property of perilla oil due to high α-linolenic acid. Alternatively, appropriate application ofantioxidant to the oil can be considerable. 지난 40 여년간 한국인의 식이지방의 섭취는 하루 17 g에서46 g으로 약 2.5배 이상 증가하였다. 들깨는 ALA를 풍부하게 함유한 전통적인 식량자원이다. 대부분의 식물유에 풍부한 LA (ω-6)의 체내 대사물인 AA로부터 생성되는 생리물질은 혈전, 동맥경화, 염증증상 등의 불리한 생리적 작용을 유발한다. 반면에 ALA의 대사산물인 EPA는 AA와 경쟁적으로 작용하여 궁극적으로바람직한 방향으로 생리적 균형을 유지하도록 한다. 그러나 들깨유는 특성상 산화되기 쉬워 저장성과 상품성이 제한적이다. 최근 유전공학을 이용하여 적절한 수준의 ω-6/ω-3 지방산의 비율을 갖는 품종육종이 활발하게 진행되고 있다. 이러한 기술은 기능성과 저장성이 우수한 들깨유를 생산하기 위한 유지자원 개발에 적용할 수 있을 것이다. 덧붙여, 들깨에 항산화물질의 강화는 들깨유의 기능을 강화하는 대안 전략으로 고려될 수 있다.

      • KCI등재

        어성초추출물투여가 흰쥐의 간장과 혈청의 지질 및 과산화지질함량에미치는 효과

        최용순 한국자원식물학회 1998 한국자원식물학회지 Vol.11 No.2

        The feeding effects of Herba hottuynia extracts on the lipids profiles and the content of TAB-reactive substances were evaluated in rats fed a high cholesterol diet. Hot water or ethanol extracts of the dried leave were evaporated and lyophilized . The experimental animals wer edevided to four groups and fed the following diets for 4 weeks : BAsal (cholesterol-free diet), CHOL(cholesterol-enriched diet),CW (cholesterol plus water extract) and CE(cholesterol plus ethanol extract). Dietary cholesterol increased significantly the activities of serum GOT and GPT, but the extracts feeding (0.5% of diet) did not influence the activities induced by dietary cholesterol. Although dietary cholesterol increased significantly the concentrationof serum andliver cholesterol, it tended to decrease the concentation of serum triglycerides. CHolesterol feeding had a lowering effect on the lipid peroxidation value of serum, but not inliver.Furthermore, the extracts feeding, especially water extract, decreased markedly the liver peroxidation value. The results suggest that Houttyunia cordata extracts have an in vivo antioxidant effect, judged from the TBA value in the liver rats fed a high cholesterol diet.

      • SCOPUSKCI등재

        형태학적 형질과 분자 표지들을 이용한 콩 유전자원의 분류

        최용순,김남수,신영범,최익영,임성희,김두환 한국유전학회 2000 Genes & Genomics Vol.22 No.2

        Detection and characterization of genetic diversity in germplasm are the critical steps for crop improvement. We have analyzed the genetic variation in a set of 108 different soybean accessions with agronomic traits and molecular markers, and tried to detect the association between the molecular diversity and agronomic trait variation. 10 agronomic traits including plant height, leaf shape, number of branches per plant, number of nodes per plant, number of podes per plant, 100-seed weight, days to flowering, days from flowering to maturity, days to maturity, and crude oil content showed high variation among the soybeans. Genetic correlation among traits was also sought. Plant height and 100-seed weight showed significant correlation coefficient with many other traits. In principal component analysis, 70% of the total variation were accounted by the first 4 principal components and days to maturity among ten agronomic traits took the largest proportion of the variation. The 108 soybean lines were grouped into 12 clusters at the minimum similarity of 0.815 with Simple Sequence Repeated DNA Polymorphism (SSRP) and Amplified Fragment Length Polymorphism (AFLP) markers. The clustering pattern did not permit the grouping of the soybean lines according to their geographic origins. In an attempt to associate the variation of agronomic traits with the molecular diversity, except for the number of pods per plant, the other nine agronomic traits showed highly significant differences between one or more of the molecular subclusters at the Least Significant Difference (LSD) level of 5%. Although most of the studies on the association of the agronomic traits with the molecular markers were done with the molecular maps, our attempt could provide another mean for detecting the association of the agronomic trait variation with molecular diversity.

      • KCI등재

        PC-Crash를 이용한 SUV의 전복사고 거동 및 충돌속도 예측에 관한 연구

        최용순,백세룡,정종길,조정권,윤준규 한국인터넷방송통신학회 2018 한국인터넷방송통신학회 논문지 Vol.18 No.2

        Along with the recent increase in traffic volume of vehicles, accidents involving rollover of vehicles have been rapidly increased, resulting in an increase casualties. And to prevent this, various technologies such as vehicle crash test equipment and analysis program development have been advanced. In this study, the applied vehicle model is FORD EXPLORER model, and PC-Crash program for vehicle collision analysis is used to predict the rollover accident behavior of SUV and the collision velocity. Compared with the actual rollover behavior of SUV through the FMVSS No 208 regulations, the analysis results showed similar results, the characteristics of the collision velocity and roll angle showed a tendency that the error rate slightly increased after 1000 msec. Then, as a result of considering using the database of NHTSA, it is shown that the rollover accident occur most frequently in the range of the collision velocity of 15~77 km/h and the collision angle of 22~74°. And it is possible to estimate the vehicle speed and collision time when the vehicle roof is broken by reconstructing the vehicle starting position, the roof failure position and the stop position by applying the actual accident case. 최근 자동차 교통량의 증가로 인해 차량 전복사고가 급증하여 이에 따른 인명피해가 증가해왔으며, 이를 방지하기 위한 차량충돌 실험장비 및 해석프로그램 개발 등의 다양한 기술이 진보되고 있다. 본 연구에서는 적용한 차량모델은 미국 FORD사의 EXPLORER 차종이고, Rollover 해석은 차량충돌해석에 상용되고 있는 PC-Crash 프로그램을이용하여 SUV의 전복사고 거동 및 충돌속도를 예측하였다. 그 해석결과로 FMVSS No. 208 법규를 통한 SUV차량의실제 Rollover 거동과 비교할 때 유사한 결과를 보여주었으며, 충돌속도 및 롤각의 특성은 1000 msec 이후부터는 다소 오차율이 커지는 경향을 나타냈다. 그리고 NHTSA의 데이터베이스를 활용하여 고찰한 결과로 충돌속도 15~77 km/h, 충돌각도 22~74° 범위에서 전복사고가 가장 많이 발생함을 나타냈고, 실제 사고사례를 적용함으로써 차량 출발위치, Roof 파손위치, 정지위치를 재현시켜 차량 Roof가 파손될 때 차량속도 및 충돌시간을 예측할 수 있었다.

      • KCI등재

        LS-DYNA 해석을 통한 SUV의 충돌인자에 따른 Roof Crush 평가 예측

        최용순,김천호,김성호,윤준규 한국기계기술학회 2018 한국기계기술학회지 Vol.20 No.5

        Recently the incidence of rollover accidents has increased due to the increase of SUV, and the probability of occupant injury in rollover accidents is very high, so research is needed accordingly. In this study, PC-CRASH, which is a program used for traffic accident analysis, is used for checking rollover speed and rollover angle of each situation in case of rollover accident, and applied to design variables of LS-DYNA which is finite element analysis program, so deformation displacements of roof according to collision velocity and angle were derived. Also, it is possible to predict rollover vehicle speed by using the derived value and the measured deformation displacement of roof in actual rollover accident, and it is possible to reconstruct accident more accurately by applying to PC-Crash which is traffic accident reconstruction program, so it is thought that it can be utilized analyzing traffic accident usefully.

      • KCI등재

        셀레늄의 영양생화학

        최용순,죤 에드워드 헤스케스 한국식품영양과학회 2006 한국식품영양과학회지 Vol.35 No.6

        Selenium (Se) obtained from dietary sources including cereals, grains and vegetables is an essential micronutrient for normal function of the body. Plants convert Se into selenomethionine and incorporate it into proteins in place of methionine, while higher animals synthesize selenoproteins containing selenocysteine. Excessive Se in the body is methylated stepwise to methylated selenium metabolites from selenide. Both inorganic and organic forms of selenium can be the nutritional sources in human, and they are transformed to selenide and then the amino acid selenocysteine attached to a specific tRNAser(sec). The selenocysteine (Sec) is incorporated into selenoprotein sequences by the UGA codon. The decoding of UGA as Sec requires specific mechanisms because UGA is normally read as a stop codon: cis acting sequences in the mRNA (the sele nocysteine insertion sequence, SECIS, within the 3'untranslated region) and trans acting factors dedicated to Sec incorporation are required for incorporation of Sec during translation of selenoprotein mRNAs. Approxi mately 25 selenoproteins have been identified in mammals. Several of these, including glutathione peroxidases, thioredoxin reductases and selenoprotein P, have been purified or cloned, allowing further characterization of their biological function. The antioxidant properties of selenoproteins help prevent cellular damage from free radicals which may contribute to the development of chronic disease such as cancer and heart disease. Other selenoproteins have important roles in regulation of thyroid function and play a role in the immune system. Daily selenium intake was reported to be 42.0±16.9 g/day in Korean adult women. This review focuses on the metabolism and biological functions of selenium, and the nutritional status of selenium in the Korean population.

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