The Effect of Sa-am acupuncture on Knee Osteoarthritis

( Moo Hong Min ),( Yeong Gon Choi ),( Yun Ju Kim ),( Hi Joon Park ),( Sam Chool Lee ),( Ho No Joo ),( Seung Moo Han ),( Sa Bi Na Lim ) 대한경락경혈학회 2009 Korean Journal of Acupuncture Vol.26 No.4

Objective: Acupuncture has been widely used throughout the world for the treatment of knee osteoarthritis (knee OA). This study investigated whether acupuncture, particularly Sa-am acupuncture, could be effective in relieving pain and improving the symptoms of knee OA. Method: This study was conducted as a prospective, randomized, controlled, and patient- and investigator- blinded clinical trial. Forty volunteers with knee OA participated in the study. All participants were screened through an inclusion and exclusion criteria. Thirty four participants completed the clinical trial. In total, forty subjects were randomly selected to receive Sa-am acupuncture. Eight sessions of acupuncture were given at the contralateral side of the problematic knee for 4 weeks. Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index (KWOMAC) scores were measured twice: at the beginning and end of the clinical trial period. Both the Patient Global Assessment and physical health scores based on the 36-Item Short-Form Health Survey were also used to measure the results. Results: Compared to the pre-trial scores, the Sa-am acupuncture group (n=34) showed a significant decrease in KWOMAC total scores according to a paired t -test. The Sa-am acupuncture group also showed significant improvement in the Patient Global Assessment when compared to the pre-trial. Conclusions: Sa-am acupuncture for knee OA resulted in an improved KWOMAC total score. This was mostly driven by the function component score that was greatly affected by acupuncture. However, further studies with expanded designs are needed to solidify this finding with scientific rigor.

The Effect of Sa-am acupuncture on Knee Osteoarthritis

Min, Moo-Hong,Choi, Yeong-Gon,Kim, Yun-Ju,Park, Hi-Joon,Lee, Sam-Chool,Joo, Ho-No,Han, Seung-Moo,Lim, Sa-Bi-Na Society for Meridian and Acupoint 2009 Korean Journal of Acupuncture Vol.22 No.1

Objective : Acupuncture has been widely used throughout the world for the treatment of knee osteoarthritis (knee OA). This study investigated whether acupuncture, particularly Sa-am acupuncture, could be effective in relieving pain and improving the symptoms of knee OA. Method : This study was conducted as a prospective, randomized, controlled, and patient- and investigator-blinded clinical trial. Forty volunteers with knee OA participated in the study. All participants were screened through an inclusion and exclusion criteria. Thirty four participants completed the clinical trial. In total, forty subjects were randomly selected to receive Sa-am acupuncture. Eight sessions of acupuncture were given at the contralateral side of the problematic knee for 4 weeks. Korean translation of Western Ontario and McMaster Universities Osteoarthritis Index (KWOMAC) scores were measured twice: at the beginning and end of the clinical trial period. Both the Patient Global Assessment and physical health scores based on the 36-Item Short-Form Health Survey were also used to measure the results. Results : Compared to the pre-trial scores, the Sa-am acupuncture group (n=34) showed a significant decrease in KWOMAC total scores according to a paired t-test. The Sa-am acupuncture group also showed significant improvement in the Patient Global Assessment when compared to the pre-trial. Conclusions : Sa-am acupuncture for knee OA resulted in an improved KWOMAC total score. This was mostly driven by the function component score that was greatly affected by acupuncture. However, further studies with expanded designs are needed to solidify this finding with scientific rigor.

대장의 편평샘종과 편평형 조기대장암에서 E-cadherin 및 β-catenin 발현

진소영,홍사준 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.1

Backgrounds : Colonic flat adenomas are presented as flat lesion endoscopically and are associated with high incidence of high grade dysplasia and carcinoma even though their small size. Recently reduced membranous expression of cell adhesion complex such as E-cadherin and β-catenin is known to be related to the wide spread and nodal metastasis in human cancers including colon cancers. However, most studies are restricted to the advanced colon cancer and few studies have been done for the colonic adenomas. Object : We tried to evaluate the availability of E-cadherin and β-catenin as the early marker of malignant conversion in flat adenomas of the colon. Materials and Methods : Immunohistochemistry was done using 27 cases of colonic flat adenomas and 7 cases of early colon cancers. Results : The overall reduced membranous expression rate for E-cadherin in colonic flat adenomas and early colon cancer was 44.1%(15/34). Membranous expression was significantly reduced as the degree of dysplasia or carcinoma increase(p<0.05). The overall reduced membranous expression rate for β-catenin was 52.9%(18/34) in colonic flat adenomas and early colon cancers. Non-membranous expression rate for β-catenin (30/34) had a tendency to increase as the degree of dysplasia or carcinoma increase but it was not statistically significant. Non-membranous expression could be seen in the cytoplasm (79.4%) and/or in the nucleus (58.8%). Focal nuclear β-catenin expression was seen in 8 cases and diffuse nuclear expression in 12 cases. Diffuse nuclear β-catenin expression rate was significantly increased as the degree of dysplasia or carcinoma increase(p<0.05). Altered expression of E-cadherin and β-catenin in colonic flat adenomas and early colon cancers was not significantly correlated. Conclusion : Reduced expression of E-cadherin and diffuse nuclear staining of β-catenin can be used as the early marker to predict the malignant conversion in colonic flat adenomas.

백제국사의 초상에 (肖像) 대하여

홍사준(Sa Joon Hong) 충남대학교 백제연구소 1981 百濟硏究 Vol.12 No.-

수덕사구기와 (修德寺舊基) 백석사고 (白石寺考)

홍사준(Sa Joon Hong) 충남대학교 백제연구소 1973 百濟硏究 Vol.4 No.-

炭峴考

洪思俊(Hong Sa-joon) 역사학회 1967 역사학보 Vol.35·36 No.-

양측성, 재발성 자연기흉을 동반한 폐 조직구증

홍사준 ( Sa Joon Hong ),안강현 ( Kang Hyun Ahn ),이원영 ( Won Yeon Lee ),공수정 ( Sue Jung Kong ),용석중 ( Suk Joong Yong ),신계철 ( Kye Chul Shin ) 대한결핵 및 호흡기학회 1994 Tuberculosis and Respiratory Diseases Vol.41 No.2

月精寺八角九層石塔 解體復原略報

洪思俊(Hong Sa-joon) 한국미술사학회 1971 美術史學硏究 Vol.- No.112

류마티스관절염의 질환 활성도 평가에 대한 Performance test의 의의에 관한 연구

홍사준 ( Sa Joon Hong ),이수곤 ( Soo Kon Lee ) 대한류마티스학회 1994 대한류마티스학회지 Vol.1 No.2

RA환자에 대한 질환의 활성도 평가방법으로 관절 기능 수행검사, ADL 설문지와 관절지수 및 Acute phae reactnt 등을 시행하여 다음과 같은 결과를 얻었다. 1 관절기능 수행검사는 통일한 환자에 대한 2명의 측정 자간에 양악의 악력 (r=0.92, P<0.001), 7.5M 정상 보행속도(r=0.96, P<0.001)와 Button test(r=0. 58, P<0. 1)의 결과를 보였다 2. 관절기능 수행검사는 3가지 관절지수와 상관성은 있었으나 ARA 관절지수가 가장 높은 상관성을 보였다. 3. 관절기능 수행검사는 ADL score와 상관성을 보였으나 ADL pain score가 가장 높은 상관성을 보였다. 4. 관절기능 수행검사는 ESR보다 CRP에서 더 높은 상관성을 보였다. 이상의 결과로 관절기능 수행검사는 RA환자에 대한 염증정도에 대한 질환의 활성도의 양적인 평가에 대한 자료를 제공하는 유용한 검사방법으로서 ADL 통증 설문, ARA 관절지수와 CRP등과 높은 상관 성을 보였으며 RA환자를 대상으로 치료에 대한 반응과 질환의 진행여부의 평가에 도움을 줄 수 있다. Objective: Inflammation has long been recongnized as notoriously difficult to measure both in clinical practice and in the laboratory methods. The methods used to clinical assess rheumatoid arthritis should share the following four parameters: validity, sensitivity, reliability and simplicity. Our purposes were evaluate mehtods of accurately reflecting disease activity in rheumatoid arthritis. Methods: We examed 32 cases (male: 4, famale: 28 and mean age: 51 years) of rheumatoid arthritis. The clinical assessment included the following: ① performance scales including grip strength, button test, and 7.5 M walking time. ② activity of daily living(ADL) questionnaires. ③ articular indices including Ritchie, ARA and restricted joint index. ④ Laboratory assessment, Made on at the same time with the clinical assessment, included follwing: erythrocyte sedimentation rate and CRP. Results: 1. Performance scale scores were well correlated with articular indeces but ARA index showed the most frequent and strongest correlations with performance scale. 2. Performance scale score were well correlated with ADL score but ADL pain score showed the most frequent and the strongest correlation. 3. Performance scale score were more strongly correlated with CRP than with ESR. Conclusion: The performance scale score appear to provide useful data for quantitative assessment of inflammatory activity of joints in the routine care of RA.

문헌에 (文獻) 나타난 백제산업

홍사준(Sa Joon Hong) 충남대학교 백제연구소 1972 百濟硏究 Vol.3 No.-