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Development of Nanobio Sensors & Diagnosis Chip for Potential Applications based on Insect Models
Kyoung G. Lee,Tae Jae Lee,Sujeong Shin,Moon Keun Lee,Nam Ho Bae,Seok O Yun,Seok Jae Lee 한국응용곤충학회 2016 한국응용곤충학회 학술대회논문집 Vol.2016 No.04
Microfluidics based on nanobio sensors technologies can provide convenient and accurate diagnosis tools. In this talk, we present recent developments of nanobio sensors & diagnosis chip using microfluidics, with special emphasis on disposable plastic devices format. In detail, we overview of the common methods used in the fabrication of polymer microfluidic systems, including replica and injection mold-ing. Also we explain the different methods by which on-chip operations—such as the pumping and valving of fluid flow, the mixing of different reagents, and the separation and detection of different biochemical species implemented in a microfluidic format. Finally, a few select biotechnological applications of microfluidics are presented to illustrate both the utility of this technology and its potential applications with insect models in the near future.
Lee, Tae Il,Lee, Sangmin,Lee, Eungkyu,Sohn, Sungwoo,Lee, Yean,Lee, Sujeong,Moon, Geondae,Kim, Dohyang,Kim, Youn Sang,Myoung, Jae Min,Wang, Zhong Lin WILEY‐VCH Verlag 2013 ADVANCED MATERIALS Vol.25 No.21
<P><B>A high‐yield solution‐processed ultrathin (<10 nm) trigonal tellurium (t‐Te) nanowire (NW)</B> is introduced as a new class of piezoelectric nanomaterial with a six‐fold higher piezoelectric constant compared to conventional ZnO NWs for a high‐volume power‐density nanogenerator (NG). While determining the energy‐harvesting principle in a NG consisting of t‐Te NW, it is theoretically and experimentally found that t‐Te NW is piezoelectrically activated only by creating strain in its radial direction, along which it has an asymmetric crystal structure. Based upon this mechanism, a NG with a monolayer consisting of well‐aligned t‐Te NWs and a power density of 9 mW/cm<SUP>3</SUP> is fabricated.</P>
( Sujeong Kim ),( Subeen Lee ),( Hyun Jung Lee ),( Yoon Hee Lee ),( Gun Oh Chong ),( Dae Gy Hong ),( Yoon Soon Lee ) 대한산부인과학회 2020 대한산부인과학회 학술대회 Vol.106 No.-
Objective: This study aimed to compare the surgical outcomes between robotic single-site myomectomy (RSSM) and single-port laparoscopic myomectomy (SPLM) by propensity score (PS) matching analysis. Methods: We included the retrospective data of 276 patients who underwent SPLM and 82 patients who underwent RSSM. Then, we conducted a PS matching analysis to control selection bias using age, gravidity, parity, body mass index, previous history of pelvic surgery, preoperative hemoglobin (Hb) level, preoperative c-reactive protein (CRP) level, and the number, type, and weight of myoma. We selected 76 patients for each group. Results: The matched RSSM group had a shorter hospital stay (OR=0.614, 95% CI=0.4140.913, p=.016) but had a longer operation time (OR=1.022, 95% CI=1.0101.034, p=.000) than the SPLM group. The former group also showed comparable blood loss (OR=1.006, 95% CI=0.9981.014, p=.138), Hb drop (OR=0.910, 95% CI=0.6571.263, p=.574), CRP change (OR=1.174, 95% CI=0.9991.379, p=.051), and complication rate (OR=0.846, 95% CI=0.1076.704, p=.874). Conclusion: The exact difference between SPLM and RSSM is difficult to determine because of the heterogeneity of the disease. The clinical outcomes of RSSM after PS matching analysis revealed the advantages of shorter hospital stays; comparable blood loss, Hb drop, CRP change, and complication rate; and longer operation times compared with those of SPLM.
Kang, Jian,Song, Young Joo,Jeon, Sujeong,Lee, Junghwa,Lee, Eunsook,Lee, Ju-Yeun,Lee, Euni,Bang, Jae Seung,Lee, Si Un,Han, Moon-Ku,Oh, Chang Wan,Kim, Tackeun The Korean Neurosurgical Society 2021 Journal of Korean neurosurgical society Vol.64 No.4
Objective : While balanced crystalloid (BC) could be a relevant fluid regimen with buffer system compared with normal saline (NS), there have been no studies on the optimal fluid for surgery of an unruptured intracranial aneurysm (UIA). This study aimed to compare the effects of fluid regimens between NS and BC on the metabolic and clinical outcomes of patients who underwent surgery for UIA. Methods : This study was designed as a propensity score matched retrospective comparative study and included adult patients who underwent UIA clipping. Patient groups were categorized as NS and BC groups based on the types of pre-operative fluid and the amount of fluid administered during surgery. The primary outcomes were defined as electrolyte imbalance and acidosis immediately after surgery. The secondary outcomes were the length of stay in the intensive care unit (ICU) and duration from the end of the operation to extubation. Results : A total of 586 patients were enrolled in this study, with each of 293 patients assigned to the NS and BC groups, respectively. Immediately after surgery, serum chloride levels were significantly higher in the NS group. Compared to the NS group, the BC group had lower incidence rates of acidemia (6.5% vs. 11.6%, p=0.043) and metabolic acidosis (0.7% vs. 4.4%, p=0.007). As compared to NS group, BC group had significantly shorter duration from the end of the operation to extubation (250±824 vs. 122±372 minutes, p=0.016) and length of stay in ICU (1.37±1.11 vs. 1.12±0.61 days, p=0.001). Throughout multivariable analysis, use of BC was found to be significant factor for favorable post-operative results. Conclusion : This study showed that the patients who received BC during UIA clipping had lower incidence of metabolic acidosis, earlier extubation and shorter ICU stay compared to those who received NS. Therefore, using BC as a peri-operative fluid can be recommended for patients who undergo surgery for UIA.
Heidegger and Laotzu : the echt meaning of the ‘and’
( Lee Sujeong ) 한국하이데거학회 2019 현대유럽철학연구 Vol.0 No.55
하이데거는 여러 군데서 노자에 대해 특별한 관심을 표명했고 『도덕경』의 독일어 번역을 직접 시도하기도 했다. 그 작업을 직접 도운 샤오시이(萧師毅)의 관련 보고와 이 사실을 논한 오토 페겔러(Otto Poggeler)의 논문 이후 ‘하이데거와 노자'는 하나의 철학적 주제로서 전 세계 수많은 연구자들의 관심을 끌었다. 이 논문은 그 전후 사정과 연구의 전모를 한눈에 볼 수 있도록 개관하고, 이 두 철학자의 비교연구가 갖는 진정한 철학적 의미를 음미한다. 그 핵심은 무엇보다도 이 둘이 동일한 문제 그자체, 현상 그 자체를 각각 서로 다른 관점에서 공유하고 있다는 것이다. 그것이 원전의 철저한 텍스트분석을 통해 제시된다 Heidegger expressed his particular interest in Laotzu in several places and even attempted to translate Tao-Te-King into German. After Xiao shiyi's report about that work and Otto Pöggeler's paper that argued this issue, "Heidegger and Laotzu" became a philosophical theme that attracted the attention of many researchers around the world. This paper provides an overview of those concerns and the whole research accomplishments at a glance, and, through thorough text analysis, the true philosophical meaning of the comparison of these two philosophers as well. The key point is that the two of them share the same problem itself, the phenomenon itself, from the different perspectives.