Experimental research on flow regime and transitional criterion of slug to churn-turbulent and churn-turbulent to annular flow in rectangular channels

He Qingche,Pan Liang-ming,Zhang Luteng,Xu Wangtao,Yan Meiyue 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.11

As for two-phase flow in rectangular channels, the flow regimes especially like churn-turbulent and annular flow are significant for the physical problem like Countercurrent Flow Limitation (CCFL). In this study, the rectangular channels with cross-sections of 4 × 66 mm, 6 × 66 mm, 8 × 66 mm are adopted to investigate the flow regimes of air-water vertical upward two phase flow under adiabatic condition. The gas and liquid superficial velocities are 0 ≤ jg ≤ 20m/s and 0.25 ≤ jf ≤ 3m/s respectively which covering bubbly to annular flow. The flow regimes are identified by random forest algorithm and the flow regime maps are obtained. As the results, the transitional void fraction from slug to churn turbulent flow fluctuate from 0.47 to 0.58 which is significantly affected by the dimensional size of channel and flow rate. Besides, the void fraction at transitional points from churn-turbulent (slug) to annular flow are 0.66–0.67, which are independent with the gap size. Furthermore, a new criteria of slug to churn-turbulent flow is established in this study. In addition, by introducing the interfacial force model, the criteria of churn-turbulent (slug) flow to annular flow is verified.

Prognostic Model Built on Blood-based Biomarkers in Patients with Metastatic Colorectal Cancer

He, Wen-Zhuo,Jiang, Chang,Yin, Chen-Xi,Guo, Gui-Fang,Rong, Ru-Ming,Qiu, Hui-Juan,Chen, Xu-Xian,Zhang, Bei,Xia, Liang-Ping Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

Background: We had previously showed that the neutrophil lymphocyte ratio (NLR), ${\gamma}$-glutamyl transpeptidase (GGT) and carcinoembryonic antigen (CEA) are prognostic factors for metastatic colorectal cancer (mCRC) patients. In this study we developed a prognostic model based on these three indices. Materials and Methods: A total of 243 patients who were initially diagnosed as mCRC between 2005 and 2010 in the Sun Yat-sen University Cancer Center were studied. The endpoint was overall survival (OS). Results: NLR>3, elevated GGT and elevated CEA were confirmed as independent risk factors which could predict poor prognosis. Patients could be divided into three groups according to the number of risk factors they had. Those with two or three were defined as the high risk group, individuals with one risk factor as the modest risk group and patients without risk factor as the low risk group. The OS values for these three groups were 16.2 months (2.80~68.8), 24.2 months (4.07~79.0), and 37.2 months (12.6~87.8), respectively (p<0.001). Conclusions: We developed a simple but useful model based on NLR, GGT and CEA to provide prognostic information to clinical practice in highly selected mCRC patients. Further prospective and multi-center studies are warranted to test our model.

Mitochondrial DNA variation and phylogeography of Old World camels

Ming Liang,Siren Dalai,Yi Li,Hai Le,He Jing,Ji Rimutu 아세아·태평양축산학회 2021 Animal Bioscience Vol.34 No.4

Objective: Old World camels are a valuable genetic resource for many countries around the world due to their adaptation to the desert environment. At present, Old World camels have encountered the challenge of unprecedented loss of genetic resources. Through our research, we would reveal the population structure and genetic variation in Old World camel populations, which provides a theoretical basis for understanding the germplasm resources and origin and evolution of different Old World camel populations. Methods: In the present study, we assessed mtDNA control region sequences of 182 individuals from Old World camels to unravel genetic diversity, phylogeography, and demographic dynamics. Results: Thirty-two haplotypes confirmed by 54 polymorphic sites were identified in the 156 sequences, which included 129 domestic and 27 wild Bactrian camels. Meanwhile, 14 haplotypes were defined by 47 polymorphic sites from 26 sequences in the dromedaries. The wild Bactrian camel population showed the lowest haplotype and nucleotide diversity, while the dromedaries investigated had the highest. The phylogenetic analysis suggests that there are several shared haplotypes in different Bactrian camel populations, and that there has been genetic introgression between domestic Bactrian camels and dromedaries. In addition, positive values of Tajima’s D and Fu’s Fs test demonstrated a decrease in population size and/or balancing selection in the wild Bactrian camel population. In contrast, the negative values of Tajima’s D and Fu’s Fs test in East Asian Bactrian camel populations explained the demographic expansion and/or positive selection. Conclusion: In summary, we report novel information regarding the genetic diversity, population structure and demographic dynamics of Old World camels. The findings obtained from the present study reveal that abundant genetic diversity occurs in domestic Bactrian camel populations and dromedaries, while there are low levels of haplotype and nucleotide diversity in the wild Bactrian camel population. Objective: Old World camels are a valuable genetic resource for many countries around the world due to their adaptation to the desert environment. At present, Old World camels have encountered the challenge of unprecedented loss of genetic resources. Through our research, we would reveal the population structure and genetic variation in Old World camel populations, which provides a theoretical basis for understanding the germplasm resources and origin and evolution of different Old World camel populations.Methods: In the present study, we assessed mtDNA control region sequences of 182 individuals from Old World camels to unravel genetic diversity, phylogeography, and demographic dynamics.Results: Thirty-two haplotypes confirmed by 54 polymorphic sites were identified in the 156 sequences, which included 129 domestic and 27 wild Bactrian camels. Meanwhile, 14 haplotypes were defined by 47 polymorphic sites from 26 sequences in the dromedaries. The wild Bactrian camel population showed the lowest haplotype and nucleotide diversity, while the dromedaries investigated had the highest. The phylogenetic analysis suggests that there are several shared haplotypes in different Bactrian camel populations, and that there has been genetic introgression between domestic Bactrian camels and dromedaries. In addition, positive values of Tajima’s D and Fu’s <i>Fs</i> test demonstrated a decrease in population size and/or balancing selection in the wild Bactrian camel population. In contrast, the negative values of Tajima’s D and Fu’s <i>Fs</i> test in East Asian Bactrian camel populations explained the demographic expansion and/or positive selection.Conclusion: In summary, we report novel information regarding the genetic diversity, population structure and demographic dynamics of Old World camels. The findings obtained from the present study reveal that abundant genetic diversity occurs in domestic Bactrian camel populations and dromedaries, while there are low levels of haplotype and nucleotide diversity in the wild Bactrian camel population.

Anthocyanins in ‘Cabernet Gernischet’ (Vitis vinifera L. cv.) Aged Red Wine and Their Color in Aqueous Solution Analyzed by Partial Least Square Regression

Fu-Liang Han,Shou-Mei Jiang,Jian-Jun He,Qiu-Hong Pan,Chang-Qing Duan,Ming-Xia Zhang 한국식품과학회 2009 Food Science and Biotechnology Vol.18 No.3

Anthocyanins are considered one of the main color determinants in aged red wine. The anthocyanins in aged red wine made from ‘Cabernet Gernischet’ (Vitis vinifera L. cv.) grape were investigated by high performance liquid chromatography- electronic spray ionization- mass spectrometry (HPLC-ESI-MS) and their color presented in aqueous solution were evaluated using partial least square regression (PLS). The results showed that there were 37 anthocyanins identified in this wine, including 22 pyranoanthocyanins. The analysis of PLS indicated that different anthocyanins showed distinct color values: malvidin 3-O-(6-O-acetyl)-glucoside-4-vinylguaiacol (Mv3-acet-glu-vg) presented the highest color values, while malvidin 3-O-glucoside (Mv3-glu) showed least. Among the free non-acylated anthocyanins, peonidin 3-Oglucoside (Pn3-glu) showed the highest color values; the coumarylated anthocyanins presented higher color values than their corresponding acetylated anthocyanins and parent anthocyanins; pyranoanthocyanins presented also higher color values than their original anthocyanins; the color of anthocyanins depended on their structure. This work will be helpful to reveal evolution in aged red wine.

Peach-specific aldehyde nonanal attracts female Oriental fruit moths, Grapholita molesta (Lepidoptera: Tortricidae)

Hui-Ming Xiang,Rui-Yan Ma,Hong-Liang Diao,Xian-Wei Li,Xiao-Juan He,Yong-Fu Guo 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.4

The oriental fruit moth (OFM), Grapholita molesta (Lepidoptera: Tortricidae), is a serious pest of stone and pome fruit trees worldwide. G. molesta can switch hosts and produce multiple generations per year. Both the primary and secondary host plants of G. molesta emit aldehydes. Here, we tested whether these aldehydes are helpful for host switching of G. molesta. SPME (Solid Phase Microextraction)-GC–MS analysis identified four aldehydes (octanal, nonanal, decanal, and benzaldehyde) from volatiles of late-season yellow peach fruits. Of the four aldehydes, eletroantennogram analysis showed that nonanal produced the strongest response from the antennae of virgin and mated females. In Y-tube bioassays, only nonanal was attractive to mated G. molesta females amongst the four aldehydes, suggesting that nonanal is important for host recognition in G. molesta. In a field trial, each of the four aldehydes was tested as an attractant for both sexes of G. molesta. The traps baited with nonanal captured more female G. molesta, as compared to traps with other aldehydes and control; the traps baited with benzaldehyde captured most male G. molesta. Our research investigations provide theoretical foundation for biological control of G. molesta females. Future G. molesta lure designs should take into account sex-specific differences in the response to individual aldehydes.

Statistic Analysis on Nonuniformity of Electrical Parameters of ZnO Varistors

Jin-Liang He,Shui-Ming Chen,Se-Won Han,Han-Goo Cho,Hyung-Boo Kang 한국정보과학회 1998 Journal of Electrical Engineering and Information Vol.3 No.5

Analyzing the nonuniformity of electrical parameters of ZnO varistors is useful to select and coordinate the ZnO varistors in parallel operation to increase the protection capability of ZnO varistors. The nonuniformity of 1[mA] DC voltage and impulse residual voltage in ZnO varistors for commercial low- and high-voltage were estimated by a statistic analysis in this paper. The relative standard deviations of 1[mA] DC voltages ZnO varistors for low-voltage and rugh-voltage were 1.98[%] and 4.10[%], respectively. The respective relative standard deviations of impulse residual voltages were 2.24[%] and 3.14[%], respectively. For the distribution of 1[mA] DC voltage and impulse residual voltage, results in ZnO varistors for low- and high-voltage agreed well with the Minimum Gobble Distribution according to the Kolmogorov-Smirnov test. A close relation between the impulse residual voltage and 1[mA] DC voltage was verified by both the t-test and another test method, and the impulse residual voltage could be estimated by a voltage ratio and 1[mA] DC voltage. The current overload of ZnO varistor with reduced residual voltage was not serious at the tested deviation range by simulation analysis, therefore, there was no problem for these varistors operating in parallel.

Statistic Analysis on Nonuniformity of Electrical Parameters of ZnO Varistors

Jin-Liang He,Shui-Ming Chen,Se-Won Han,Han-Goo Cho,Hyung-Boo Kang 대한전기학회 1998 Journal of Electical Engineering and information S Vol.3 No.5

Inhibition of HBV replication and gene expression in vitro and in vivo with a single AAV vector delivering two shRNA molecules

( Zhi Li ),( Ming Liang He ),( Hong Yao ),( Qing Ming Dong ),( Yang Chao Chen ),( Chu Yan Chan ),( Bo Jian Zheng ),( Kwok Yung Yuen ),( Ying Peng ),( Qiang Sun ),( Xiao Yang ),( Marie C. Lin ),( Josep 생화학분자생물학회 2009 BMB Reports Vol.42 No.1

Three-dimensional simulation of electrochemical machining process with Lagrangian-Eulerian Formulation

Chang-Yun He,Zhi-Gang Huang,Liang Hu,Cheng-Jun Xiao,Jian-Hong Xia,Ming Wu,Jian-Qun Liu 한국생산제조학회 2014 한국생산제조시스템학회 학술발표대회 논문집 Vol.2014 No.9(2)

Molecular cloning of the duck MEF2C gene cDNA coding domain sequence and its expression during fetal muscle tissue development

Ling-Li Sun,He-he Liu,Hao-han Wang,Jian-Ming Si,Hai-bo Jin,Xin-xin Li,Chao Yang,Liang Li,Jiwen Wang 한국유전학회 2013 Genes & Genomics Vol.35 No.3

Myogenic enhancer transcription factor 2c (MEF2c), one of the members of the MEF2 family of transcription factors, plays an important role in mammalian muscle development. However, the role of MEF2c in avian muscle development still remains unclear. To understand the function of MEF2c in avian muscle development, we first cloned the duck MEF2c coding domain sequence (CDS) and analyzed MEF2c expression in duck muscle tissues of embryos from 10 days of incubation to 1 week after birth using real-time PCR technology. The results showed that the duck MEF2c CDS consists of 1,398nucleotides that encode 465 amino acids. The MEF2c duck protein contains a MADS domain, a MEF2 domain and a HJURP_C domain with high homology to related proteins in other organisms. Different expression levels of MEF2c were found in skeletal, smooth and cardiac muscle. Therefore, these results indicated that duck MEF2c has two conserved domains (a MADS and a MEF2 domain), is an indispensable regulator of muscle development, and plays an important role in the development of duck muscle.