High SMAS face lift: clinical experience

Zhijun Wang,Xiaoyan Ma,Lixiang Yang,Yan Wang,Lili Chen,Hang Lv 대한미용의학회 2018 대한미용의학회지 Vol.2 No.1

Background: The ultimate goal of facelift is to lift the sagging soft tissue as much as possible, so as to restore them to the original anatomical position for facial rejuvenation. Objective: In our High-SMAS facelift, the SMAS-platysma flap were tighten strongly, so as to obtain full and youthful facial morphologic characteristics. In addition, the effectiveness of high-SMAS was evaluated in this paper. Methods: A total of 86 cases of SMAS face lift were performed in 22 months from January 2015 to November 2016. High SMAS technique was applied in 39 cases of them. All the 39 patients were female averaged 44 (29-65) years old. Postoperative follow-up wascarried out in 18 cases for an average of 13 months (4-22 months). After the SMAS-platysma flap was dissected in the lower face and neck,the key point of operating is focus on:The middle temporal fascia and superficial temporal fascia flap was dissected carefully. Break off the ligaments medial to the zygomatic arch and on the malar process exactly, and pay attention to protect the facial nerve. So that the high-SMAS and even higher-SMAS flap can be dissected. Results: In all the 18 cases followed up, most (11/18) obtained a clear mandibular margin after operation and scored even full mark. Perfect nasolabial fold improvement was achieved in few (7/18). In terms of Ogee curve evaluation, most (15/18) made it to the level of “acceptable”, which was shared by the evaluation of lower eyelid shortening effects (13/18). Very satisfied indicators as follow: the obtuse jowl line becomes clear, midface “ogee curve” is vary from linear to curves, and the nasolabial sulcus have been improved. Conclusion: High-SMAS Facelift is one of the most effective rhytidectomy, the most prominent parts of its effect including the improvement of midface and jowl line contour. Level of Evidence: IV

Adaptive guided salp swarm algorithm with velocity clamping mechanism for solving optimization problems

Wang Zongshan,Ding Hongwei,Wang Jie,Hou Peng,Li Aishan,Yang Zhijun,Hu Xiang 한국CDE학회 2022 Journal of computational design and engineering Vol.9 No.6

Salp swarm algorithm (SSA) is a well-established population-based optimizer that exhibits strong exploration ability, but slow convergence and poor exploitation capability. In this paper, an endeavour is made to enhance the performance of the basic SSA. The new upgraded version of SSA named as ‘adaptive strategy-based SSA (ABSSA) algorithm’ is proposed in this paper. First, the exploratory scope and food source navigating commands of SSA are enriched using the inertia weight and boosted global best-guided mechanism. Next, a novel velocity clamping strategy is designed to efficiently stabilize the balance between the exploration and exploitation operations. In addition, an adaptive conversion parameter tactic is designed to modify the position update equation to effectively intensify the local exploitation competency and solution accuracy. The effectiveness of the proposed ABSSA algorithm is verified by a series of problems, including 23 classical benchmark functions, 29 complex optimization problems from CEC 2017, and five engineering design tasks. The experimental results show that the developed ABSSA approach performs significantly better than the standard SSA and other competitors. Moreover, ABSSA is implemented to handle path planning and obstacle avoidance (PPOA) tasks in autonomous mobile robots and compared with some swarm intelligent approach-based path planners. The experimental results indicate that the ABSSA-based PPOA method is a reliable path planning algorithm.

뮤지컬을 활용한 중학생 가창 수업 지도 방안 연구

Wang Zhijun,김현태 사단법인 한국융합기술연구학회 2024 아시아태평양융합연구교류논문지 Vol.10 No.1

본 연구는 뮤지컬을 활용하고 중학생의 신체적 변화인 변성기를 고려한 지도 방안을 연구하여 학습계획의 제시를 목적으로 하였다. 문헌 고찰을 통해 가창 수업과 뮤지컬을 이해하고 제재곡을 분석했으며, 이를 바탕으로 가창 수업의 내용을 구성한 다음 차시별 수업 지도안을 연구하여 다음과 같은 결론을 얻었다. 첫째, 가창 수업은 음악적 표현을 통해 학생들이 심미적인 체험을 하고 미적 가치관을 형성하여 풍요로운 삶을 누릴 수 있는 기초를 제공하였다. 가창 활동을 통해서 청소년기 학생들은 자기표현 욕구를 해소하여 심리적 안정과 풍부한 감성을 갖고 사회성과 협동심을 육성할 수 있으며, 이런 목표를 위해서는 교사의 올바른 가창 지도와 체계적인 학습 방안이 필요하였다. 둘째, 뮤지컬의 교육적 효과는 무대 위 공연을 통한 학생들의 상상력 향상과 주체자로의 성장, 그리고 다양한 감정 경험을 통한 학생들의 공감 능력 양성이었다. 셋째, 뮤지컬을 활용한 중학생 가창 수업 지도 방안에서는 음악 교과서의 수록곡 중《영웅》의 <누가 죄인인가>를 선정하여 가사 내용 및 등장인물, 노래의 형식 및 구조, 음악 요소와 창법을 분석하였다. 그리고 이를 바탕으로 발성법, 음악 요소 학습, 음악적 표현의 3가지 내용으로 수업 지도안을 구성하였다. This study aimed to research teaching methods that use music to consider the physical changes of puberty in middle school students and to propose a teaching plan based on the findings. A literature review provided an understanding of singing classes and musicals, and then analysis focused on selected songs. Based on this, the structure of the singing class content was outlined, and the session-by-session teaching guidance was researched, leading to the following conclusions: First, singing class provided the foundation for students to experience aesthetic experiences and form aesthetic values through musical expression, allowing them to enjoy a more prosperous life. Adolescents, through singing activities, could satisfy their desire for self-expression, which leads to achieving psychological stability, cultivating rich emotions, fostering sociability, and developing teamwork. For these goals, the necessity of correct vocal guidance by teachers and a systematic learning approach was important. Second, the educational effect of musicals was for students to enhance their imagination, grow as a subject through on-stage performances, and develop their empathetic abilities by enabling them to experience various emotions. Third, in the teaching method of singing class for middle school students using musicals, the song <Who is guilty> from the musical《Hero》in the music textbook was selected. And then the content of the lyrics, characters, song format and structure, musical elements, and singing methods were analyzed. Based on this, the teaching guidance was structured into three contents: vocalization, musical learning, and musical expression.

노년층의 심리적 안녕을 위한 평생교육 가창 프로그램 설계

Wang Zhijun,김현태 사단법인 한국융합기술연구학회 2024 아시아태평양융합연구교류논문지 Vol.10 No.1

본 연구는 노년층이 심리적 안정감을 얻고 성공적인 노화를 이룰 수 있도록 평생교육 가창 프로그램 설계를 연구하는 데 목적이 있다. 이를 위해서 문헌 고찰을 통해 노년층의 특성과 노인 음악교육의 필요성을 확인하고 노년층의 음악 장르 선호도를 반영한 가창 프로그램을 설계하여 다음과 같은 연구 결과를 얻었다. 첫째, 노년층은 신체적∙인지적∙사회적∙심리적 변화를 겪으며, 내면적으로 행복한 심리상태를 의미하는 심리적 안녕감은 인간의 행복 추구라는 최종 목표를 위해 삶의 질을 증진하며 성공적인 노화로 이끄는 요소였다. 둘째, 평생교육은 학습과 훈련으로 인간이 통합적으로 성장하고 인간의 갈등 해소를 위한 노력이자, 삶 속에서 필요한 학습 과정을 거쳐 개개인이 자기완성을 성취하는 것을 의미하였다. 주요 선진국들은 평생교육의 논의와 실행이 진전된 단계에 있었으나, 한국은 2019년 노인복지법에서 노인 평생교육과 관련된 내용이 포함되기 시작하였다. 평생교육으로서의 음악교육은 노년층의 신체적∙인지적∙심리적 측면에서 효과적이었다. 셋째, 평생교육 가창 프로그램은 노년층이 선호하는 음악 선호도를 반영하여 트로트, 팝, 뮤지컬로 선곡하여 노인 교육의 기본원리를 바탕으로 노화에 따른 음성 변화를 반영해 가창지도 내용을 설정하였다. 프로그램 모델은 총 12차시 수업별 주제로 세부 내용을 구성하였다. 한국 노년층의 인구가 늘어감에 따라 노년층을 위한 평생교육 비중을 높이고, 사회 구성원인 노년층이 즐겁고 행복한 사회가 되는데 초석이 되어 후속 연구가 활성화되었으면 하는 바람이다. This study aims to design a lifelong singing program for the elderly to help them achieve psychological stability and successful aging. The characteristics of the elderly were determined by the literature review, which also established the necessity for music instruction for the elderly. Based on this, a singing program reflecting the music genre preferences of the elderly was designed, and the conclusions arrived at the following: First, the elderly experienced physical, cognitive, social, and psychological changes. Psychological well-being, which indicates an internally happy psychological state, promotes the quality of life, leading to the ultimate goal of human happiness and successful aging. Second, lifelong education means humans grow holistically through learning and training, resolving conflicts, and achieving self-fulfillment. While major developed countries have advanced discussions and implementations of lifelong education, Korea began including content related to lifelong education for the elderly in the Senior Welfare Act in 2019. Music education as lifelong learning has proven effective in the physical, cognitive, and psychological aspects of the elderly. Third, the lifelong singing program was designed to reflect the musical preferences of the elderly, such as trot, pop, and musicals. The program considered the basic principles of elderly education and the vocal changes associated with aging. The program structure was divided into twelve sessions, each with a distinct theme. With the increasing population of the elderly in Korea, it is hoped that there will be an emphasis on lifelong education for them, laying the groundwork for a society where the elderly live joyfully and happily as members of society. It is believed that vigorous follow-up research will be undertaken.

The structured multiparameter eigenvalue problems in finite element model updating problems

Zhijun Wang,Bo Dong,Yan Yu,Xinzhu Zhao,Yizhou Fang 국제구조공학회 2023 Structural Engineering and Mechanics, An Int'l Jou Vol.88 No.5

The multiparameter eigenvalue method can be used to solve the damped finite element model updating problems. This method transforms the original problems into multiparameter eigenvalue problems. Comparing with the numerical methods based on various optimization methods, a big advantage of this method is that it can provide all possible choices of physical parameters. However, when solving the transformed singular multiparameter eigenvalue problem, the proposed method based on the generalised inverse of a singular matrix has some computational challenges and may fail. In this paper, more details on the transformation from the dynamic model updating problem to the multiparameter eigenvalue problem are presented and the structure of the transformed problem is also exposed. Based on this structure, the rigorous mathematical deduction gives the upper bound of the number of possible choices of the physical parameters, which confirms the singularity of the transformed multiparameter eigenvalue problem. More importantly, we present a row and column compression method to overcome the defect of the proposed numerical method based on the generalised inverse of a singular matrix. Also, two numerical experiments are presented to validate the feasibility and effectiveness of our method.

Phase transition enhanced thermoelectric performance for perovskites: The case of AgTaO3

Wang Zhijun,He Zhijian,Lei Chihou,Zou Daifeng,Liu Yunya 한국물리학회 2023 Current Applied Physics Vol.48 No.-

In general, perovskite materials, such as AgTaO3, can exhibit complex structural phase transitions when the temperature changes. Different phase structures may show distinct thermoelectric properties. However, the effects of phase transition on the thermoelectric performance of AgTaO3 have yet to be systematically investigated. Thus, in this work, the electronic structures and thermoelectric properties of the p-type AgTaO3 in various phase structures are investigated by utilizing first-principles calculations and semi-classical Boltzmann transport theory. The results show that the p-type AgTaO3 in the cubic phase shows a superior power factor because the cubic phase possesses a large Seebeck coefficient and intermediate electrical conductivity. The calculated thermoelectric performance is consistent with the predictions and explanations from the analyses of the electronic structures. When the p-type AgTaO3 is transformed from the tetragonal phase to the cubic phase, its power factor is tripled, suggesting that a suitable phase transition can improve the thermoelectric properties of perovskites.

Energy spread minimization in a cascaded laser wakefield accelerator via velocity bunching

Zhang, Zhijun,Li, Wentao,Liu, Jiansheng,Wang, Wentao,Yu, Changhai,Tian, Ye,Nakajima, Kazuhisa,Deng, Aihua,Qi, Rong,Wang, Cheng,Qin, Zhiyong,Fang, Ming,Liu, Jiaqi,Xia, Changquan,Li, Ruxin,Xu, Zhizhan American Institute of Physics 2016 Physics of plasmas Vol.23 No.5

Map-based cloning and functional analysis of the chromogen gene C in rice (Oryza sativa L.)

Shasha Zhao,Cuihong Wang,Jian Ma,Shuai Wang,Peng Tian,Jiulin Wang,Zhijun Cheng,Xin Zhang,Xiuping Guo,Cailin Lei 한국식물학회 2016 Journal of Plant Biology Vol.59 No.5

The chromogen gene C is critical for anthocyanin regulation in rice, and apiculus color is an important agronomic trait in selective breeding and variety purification. Mapbased cloning and in-depth functional analysis of the C gene will be useful for understanding the molecular mechanism of anthocyanin biosynthesis and for rice breeding. Japonica landrace Lijiangxintuanheigu (LTH) has red apiculi and purple stigmas. Genetic analysis showed that red apiculus and purple stigma in LTH co-segregated indicating control by a single dominant gene, or by two completely linked genes. Using 1,851 recessive individuals from two F2 populations, the target gene OsC was delimited to a 70.8 kb interval on chromosome 6 that contains the rice homologue of the maize anthocyanin regulatory gene C1. When the entire OsC gene and its full-length cDNA cloned from LTH were transformed into japonica cultivar Kitaake with colorless apiculi and stigmas all positive transformants had red apiculi but non-colored stigmas, validating that OsC alone was responsible for the apiculus color and represented the functional C gene. OsC was constitutively expressed in all tissues examined, with strongest expression in leaf blades. These results set a foundation to clarify the regulatory mechanisms of OsC in the anthocyanin biosynthetic pathway.

Directed Molecular Engineering of Mig6 Peptide Selectivity between Proto-oncogene ErbB Family Receptor Tyrosine Kinases

Zhijun Qiao,Shuai Wang 한국생물공학회 2021 Biotechnology and Bioprocess Engineering Vol.26 No.2

The ErbB signaling pathway plays important roles in normal physiology and cancer, which consists of four proto-oncogene receptor tyrosine kinases ErbB1/EGFR, ErbB2/Her2, ErbB3/Her3, and ErbB4/Her4. Selective targeting of different ErbB kinases would result in distinct therapeutic effects, but traditional small-molecule inhibitors generally exhibit a strong cross-reactivity over these kinases due to the very high conservation in kinase’s active site. Instead of developing small-molecule drugs to selectively target the conserved active site of ErbB kinases, we herein attempt to design peptide agents for selectively disrupting the dimerization event of these kinases at their asymmetric dimer interfaces that have a relatively low homology. Three hotspot peptides S1P1, S1P2, and S1P3 are split from the functional segment 1 (Seg1) of mitogen-inducible gene 6 (Mig6), a natural EGFR-inhibitory protein that has been observed to inactivate the kinase by disrupting its dimerization. We demonstrate that the Mig6 peptides not only inhibit EGFR, but also bind Her2, Her3, and Her4, although the peptide affinities to the four ErbB kinases are different considerably, exhibiting a typical selectivity. The S1P2 peptide locates in the core binding region of Mig6 Seg1 and contributes significantly to the segment interaction with kinases. An iteration algorithm is employed to guide the directed molecular engineering of S1P2 peptide selectivity towards each of the four kinases. Hundreds of parallel evolution running yield a series of peptide candidates with potential selectivity, which are then substantiated by fluorescence-based assays. The designed EGFR-selective peptide S1P2-p1EGFR is determined to have a moderate affinity to EGFR (Kd = 56 μM) and a high selectivity for EGFR over Her2, Her3, and H4 (FEGFR = 10.1-fold), which is improved considerably relative to wild-type S1P2 peptide (FEGFR = 2.7-fold). Structural examination observes different noncovalent interaction modes at the complex interfaces of S1P2-p1EGFR with EGFR and other three kinases, revealing a molecular origin of the peptide selectivity.

Parallel Gene Loss and Acquisition Among Strains of Different Brucella Species and Biovars

Zhijun Zhong,Yufei Wang,Jie Xu,Yanfen Chen,Yuehua Ke,Xiaoyan Zhou,Xitong Yuan,Dongsheng Zhou,Yi Yang,Ruifu Yang,Guangneng Peng,Hai Jiang,Jing Yuan,Hongbin Song,Buyun Cui,Liuyu Huang,Zeliang Chen 한국미생물학회 2012 The journal of microbiology Vol.50 No.4

The genus Brucella is divided into six species; of these, B. melitensis and B. abortus are pathogenic to humans, and B. ovis and B. neotomae are nonpathogenic to humans. The definition of gene loss and acquisition is essential for understanding Brucella’s ecology, evolutionary history, and host relationships. A DNA microarray containing unique genes of B. melitensis Type strain 16MT and B. abortus 9-941 was constructed and used to determine the gene contents of the representative strains of Brucella. Phylogenetic relationships were inferred from sequences of housekeeping genes. Gene loss and acquisition of different Brucella species were inferred. A total of 214 genes were found to be differentially distributed,and 173 of them were clustered into 15 genomic islands (GIs). Evidence of horizontal gene transfer was observed for 10GIs. Phylogenetic analysis indicated that the 19 strains formed five clades, and some of the GIs had been lost or acquired independently among the different lineages. The derivation of Brucella lineages is concomitant with the parallel loss or acquisition of GIs, indicating a complex interaction between various Brucella species and hosts.