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Geng Yan-Bo,Ding Zhao-Hua,Xiao Jing-Lin 한국물리학회 2021 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.79 No.1
In this work, the effect of parabolic potential on the properties of strongly coupled polaron in an asymmetric Gaussian quantum well (QW) has been studied. Relations of the frequency vibration and the strongly coupled polaron’s ground-state energy in an asymmetric Gaussian QW for RbCl crystals at different confinement strengths along the x and the y directions, the asymmetric Gaussian QW barrier heights, and the Gaussian confinement potential widths and temperatures have been studied using the Lee–Low–Pines unitary transformation and the linear combination operator methods. Calculations show that the absolute value of ground-state energy increased with increasing confinement strengths along the x and the y directions and asymmetric Gaussian QW barrier height, and derease with increeasing Gaussian confinement potential width, and temperature. In addition, vibrational frequency was found to decrease with increasing Gaussian confinement potential width and to increase with increasing confinement strengths along the x and the y directions, asymmetric Gaussian QW barrier height, and temperature. The five parameters involved in this paper are important physical quantities for studying the properties of Gaussian QWs, and have important physical significance for the study of nanomaterials.
Geng Shiyang,Xie Hua,Chen Liping,Chen Dong,Lu Sijing,Zhao Nan,Yang Ruiming,Wang Zhao,He Shaoheng,Zhang Huiyun 대한천식알레르기학회 2022 Allergy, Asthma & Immunology Research Vol.14 No.6
Purpose: To explore expression of SP and NK1R in basophils of allergic asthma (AA), allergic rhinitis (AR) and AR combined with AA (ARA), and influence of allergens and immunoglobulin E (IgE) mediated mechanisms on SP and NK1R expression. Methods: Expression of SP and NK1R was detected by flow cytometry, NK1R mRNA expression was detected by real time quantitative polymerase chain reaction (qPCR), and mouse AR and AA models were employed for in vivo study. Results: SP+ and NK1R+ cells increased in CCR3+ and CD123+HLA-DR− granulocytes of AA. PPE elevated proportions of SP+ cells in CCR3+ and CD123+HLA-DR− granulocytes, whereas ASWE and HDME augmented SP+ cells in CD123+HLA-DR− granulocytes of AR and ARA patients. ASWE, HDME and PPE increased proportions of NK1R+ cells in CCR3+ PBMC and CD123+HLA-DR− granulocytes of AR patients. OVA, Der p1, IL-33, IL-37, IgE and SP enhanced NK1R expression on KU812 cells. NK1R expressing basophils were increased in blood of OVA sensitized and challenged AR and AA mice. FcεRI-KO AA mice seemed to have less NK1R+ basophils than WT AA mice in their blood. Conclusion: CCR3+ and CD123+HLA-DR− cells are likely involved in AA and AR via SP and NK1R. IgE-related mechanism may participate in upregulation of NK1R expression.
Song-You Wang,Zhao-Hua Geng,Gang Wang,Song Wu,Liang-Yao Chen,Yu Jia 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4
In this paper, the electronic and the optical properties of oxides for group-IV elements in an inverse Ag2O structure, including Si, Ge, and Sn, and their ternary alloys, were studied with the density function theory of first principles. The results show that they have a high-density phase and a high dielectric constant. Moreover, the lattice constants of Si0.5Ge0.5O2 and SiO2 are really close to those of Si(100) surfaces, suggesting the possibility of forming a defect-free superlattice. With changing element, the calculated results show that the lattice constants of the ternary alloys tend to be bigger while the energy gaps show a different trend. The optical properties of these compounds as functions of physical quantities, such as the density of states, the complex dielectric function,and the static dielectric constant, are given to support the potential applications of the compounds in the future.
Development and characterization of a fully functional small anti-HER2 antibody
( Jie Gao ),( Bo Hua Le ),( Hui Mei Li ),( Xun Min Zhang ),( Da Peng Zhang ),( Lei Zhao ),( Chong Wang ),( Chen Fang ),( Wei Zhu Qian ),( Sheng Hou ),( Geng Kou ),( Hua Feng Wei ),( Shu Shi ),( Hao Wa 생화학분자생물학회 2009 BMB Reports Vol.42 No.10
First-principles Study on the Electronic Structures and the Optical Properties of Hg1−xCdxTe
Song-You Wang,Gang Wang,Song Wu,Zhao-Hua Geng,Liang-Yao Chen,Yu Jia 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.56 No.4
The electronic structures and the optical properties of the direct-band-gap infrared alloy Hg1−xCdxTe (x = 0.250, 0.375, 0.500, 0.625, 0.875, and 1.000) were obtained using the local spin density approximation (LSDA) in the density functional theory (DFT). The calculated lattice constants are in agreement with these calculated using Vergard’s law and the band structures of these alloys are similar. The three peaks of the imaginary part in the dielectric function reveal that the conduction bands lift with increasing x. The calculated static dielectric constants of these alloys were shown to behave as a parabolic function. The results for the loss functions and effective electronic densities show that few electrons take part in the interband transitions.
Guanfeng Zheng,Qingtai Xiao,Shusheng Zhu,Hua Wang,Jian Geng,Shuang Zhao,Junwei Huang 한국화학공학회 2022 Korean Journal of Chemical Engineering Vol.39 No.7
The relationship between heat transfer effect and influencing factors in direct contact with evaporator isstudied. It is important to optimize the design and setting of direct contact heat exchangers and further improve theheat transfer process of heat exchangers by understanding the influencing factors of direct contact evaporator. Themethods used are grey correlation analysis, variational mode decomposition and least square support vector machinealgorithm to calculate the experimental heat transfer coefficient. The conclusions are that grey relation analysis can findthe complex relationship between different influencing factors and reduce the amount of data to improve the accuracyof prediction. Hence, the novelty of this paper is to propose a simple, efficient and accurate hybrid prediction model forVHTC prediction. The place where it goes beyond previous efforts in the literature is that different influencing factorson the heat transfer performance in the direct contact heat transfer process are considered. The results show that theprediction accuracy of the heat transfer coefficient can be improved by 7% by optimizing the data only with grey correlationanalysis. The prediction accuracy can be improved up to 53% after using the hybrid model.
Li-jun Liang,Chen-xi Hu,Yi-xuan Wen,Xiao-wei Geng,Ting Chen,Guo-qing Gu,Lei Wang,You-you Xia,Yong Liu,Jia-yan Fei,Jie Dong,Feng-hua Zhao,Yiliyar Ahongjiang,Kai-yuan Hui,Xiao-dong Jiang 대한암학회 2020 Cancer Research and Treatment Vol.52 No.2
Purpose This study aimed to investigate the potential systemic antitumor effects of stereotactic ablative radiotherapy (SABR) and apatinib (a novel vascular endothelial growth factor receptor 2 inhibitor) via reversing the immunosuppressive tumor microenvironment for lung carcinoma. Materials and Methods Lewis lung cancer cells were injected into C57BL/6 mice in the left hindlimb (primary tumor; irradiated) and in the right flank (secondary tumor; nonirradiated). When both tumors grew to the touchable size, mice were randomly divided into eight treatment groups. These groups received normal saline or three distinct doses of apatinib (50 mg/kg, 150 mg/kg, and 200 mg/kg) daily for 7 days, in combination with a single dose of 15 Gy radiotherapy or not to the primary tumor. The further tumor growth/regression of mice were followed and observed. Results For the single 15 Gy modality, tumor growth delay could only be observed at the primary tumor. When combining SABR and apatinib 200 mg/kg, significant retardation of both primary and secondary tumor growth could be observed, indicated an abscopal effect was induced. Mechanism analysis suggested that programmed death-ligand 1 expression increased with SABR was counteract by additional apatinib therapy. Furthermore, when apatinib was combined with SABR, the composition of immune cells could be changed. More importantly, this two-pronged approach evoked tumor antigen–specific immune responses and the mice were resistant to another tumor rechallenge, finally, long-term survival was improved. Conclusion Our results suggested that the tumor microenvironment could be managed with apatinib, which was effective in eliciting an abscopal effect induced by SABR.