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      • KCI등재

        Synthesis of Polymeric Phthalocyanine Sulfonate Photosensitizer and Its Photodegradation on Rhodamine B in Aqueous Medium

        Peng Zhao,우재완,박용성,Yenan Song,Fushi Zhang 한국고분자학회 2010 Macromolecular Research Vol.18 No.5

        Novel phthalocyanine sulfonate (H2PPcSx) was synthesized from the sulfonation of a steric polymeric phthalocyanine and investigated as a photocatalyst in a homogenous system. The molecular weight of H2PPcSx was characterized as 9213-11692 by MALDI-TOF MS, classified as an oligomer with a 14-18 degree of polymerization. The electronic spectrum indicated a less aggregative tendency of H2PPCSx than the usual monomeric phthalocyanine photocatalyst. Efficient photodegradation of butyl Rhodamine B (bu Rh B) catalyzed by H2PPcSx was achieved in a homogenous solution; the spectral character indicated that decomposition occurred on the benzene ring in the Rh B molecular. For a 50 mg L-1 bu Rh B solution, the percentage degradation reached 95% in 4 h using 100 mg H2PPcSx as a photocatalyst. A mechanism involving the participation of both singlet oxygen and radicals was established for the photodegradation.

      • KCI등재

        First-principles study of the switching characteristics of the 15,16-dinitrile DDP/CPD-based optical molecular switch with carbon nanotube electrodes

        Peng Zhao,Chang-feng Fang,Yi-ming Wang,Ya-xi Zhai,De-sheng Liu 한국물리학회 2009 Current Applied Physics Vol.9 No.6

        We have studied the switching characteristics of an optical molecular switch based on the 15,16-dinitrile dihydropyrene/cyclophanediene (DDP/CPD) molecule with two single-walled carbon nanotube (SWCNT) electrodes using first-principles transport calculations. It is shown that the DDP shows an overall higher conductance than the CPD at low bias which is independently of the SWCNT chirality. Meantime, the conductance of the molecular switch can be tuned by the chirality of the SWCNT. We have studied the switching characteristics of an optical molecular switch based on the 15,16-dinitrile dihydropyrene/cyclophanediene (DDP/CPD) molecule with two single-walled carbon nanotube (SWCNT) electrodes using first-principles transport calculations. It is shown that the DDP shows an overall higher conductance than the CPD at low bias which is independently of the SWCNT chirality. Meantime, the conductance of the molecular switch can be tuned by the chirality of the SWCNT.

      • SCIESCOPUSKCI등재

        Opportunistic Routing for Bandwidth-Sensitive Traffic in Wireless Networks with Lossy Links

        Zhao, Peng,Yang, Xinyu The Korea Institute of Information and Commucation 2016 Journal of communications and networks Vol.18 No.5

        Opportunistic routing (OR) has been proposed as a viable approach to improve the performance of wireless multihop networks with lossy links. However, the exponential growth of the bandwidth-sensitive mobile traffic (e.g., mobile video streaming and online gaming) poses a great challenge to the performance of OR in term of bandwidth guarantee. To solve this problem, a novel mechanism is proposed to opportunistically forwarding data packets and provide bandwidth guarantee for the bandwidth-sensitive traffic. The proposal exploits the broadcast characteristic of wireless transmission and reduces the negative effect of wireless lossy links. First, the expected available bandwidth (EAB) and the expected transmission cost (ETC) under OR are estimated based on the local available bandwidth, link delivery probability, forwarding candidates, and prioritization policy. Then, the policies for determining and prioritizing the forwarding candidates is devised by considering the bandwidth and transmission cost. Finally, bandwidth-aware routing algorithm is proposed to opportunistically delivery data packets; meanwhile, admission control is applied to admit or reject traffic flows for bandwidth guarantee. Extensive simulation results show that our proposal consistently outperforms other existing opportunistic routing schemes in providing performance guarantee.

      • Aberrant Expression of HOXA5 and HOXA9 in AML

        Zhao, Peng,Tan, Li,Ruan, Jian,Wei, Xiao-Ping,Zheng, Yi,Zheng, Li-Xia,Jiang, Wei-Qin,Fang, Wei-Jia Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.9

        Background: Aberrant expression of HOX gene expression has been observed in cancer. The purpose of this study was to investigate the alteration of HOXA5 and HOXA9 expression and their clinical significance in acute meloid leukemia (AML). Materials and Methods: The expression of HOXA5 and HOXA9 genes of bone marrow samples from 75 newly diagnosed AML patients and 22 healthy controls for comparison were examined by Real-time quantitative PCR (RQ-PCR) assay. Statistical analysis was conducted to evaluate HOXA5 and HOXA9 expression as possible biomarkers for AML. Results: The results showed that the complete remission rate (52.6%) of the patients who highly expressed HOXA5 and HOXA9 was significantly lower than that (88.9%) in patients who lowly express the genes (P=0.015). Spearmann correlation coefficients indicated that the expression levels for HOXA5 and HOXA9 genes were highly interrelated (r=0.657, P<0.001). Meanwhile, we detected significant correlations between HOXA9 expression and age in this limited set of patients (P=0.009). Conclusions: The results suggest a prognostic impact of increased expression of HOXA5 and HOXA9 in AML patients.

      • KCI등재

        Mechanical properties and cushioning mechanism of shear thickening fluid

        Peng Zhao,Qian Chen,Xue Gao,Zhaoyong Wu 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.11

        Shear thickening fluid (STF) is one type of dispersed system with rapidly changing rheological properties under an impulse load. The apparent viscosity of such a suspension system changes dramatically under high-speed impact, and the system can even change from suspension to quasi-solid. Once the load is removed, the STF will quickly return to its original state. In this paper, a mechanical model based on a particle-jammed model and added mass was proposed by calculating the acceleration response of the impact bar, and the local hardening phenomenon of STF in the low-speed impact test was interpreted. Then with the low-speed impact test, the rheological properties of STF in the cushioning process were recorded by a high-speed camera. Meanwhile, a comparison was made with the cushioning efficiency of AV-200, a closed-cell foam material, by using the force-displacement curve. Finally, based on the constitutive relation of STF and by using the fluid-solid coupling method in the FEM, the lowspeed impact test of STF was analyzed to obtain more comprehensive dynamic characteristics. The acceleration response obtained in the test was consistent with the theoretical results, which further verified the rationality and effectiveness of the theoretical model. Compared with AV-200, STF has a cushioning efficiency of 50 %-60 %, and its cushioning performance was superior to AV-200. Starting with the rheological cloud map of STF and the acceleration response of the impact bar by the numerical model, a comparison was made with the results of low-speed impact test, and a good agreement is observed.

      • KCI등재

        Insights into chlorantraniliprole resistance of Chilo suppressalis: Expression profiles of ATP-binding cassette transporter genes in strains ranging from low- to high-level resistance

        Peng Yingchuan,Zhao Jun,Sun Yang,Wan Peng,Hu Yanyue,Luo Guanghua,Qin Wenjing,Huang Shuijin 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.2

        The ATP-binding cassette (ABC) proteins are involved in trans-cellular transport of substances at inverse con centrations. After ABC genes were discovered to be involved in multidrug resistance in humans, increased attention was paid to the role of insect ABC genes in pesticide resistance. Chilo suppressalis, the most important Lepidopteran pest in rice production, has developed resistance to the insecticide chlorantraniliprole. However, few of the ABC genes that contribute to chlorantraniliprole resistance have been studied. Here, 47 genes encoding ABC transporters were identified, including five CsABCA, seven CsABCB, ten CsABCC, two CsABCD, one CsABCE, three CsABCF, 15 CsABCG, and four CsABCH genes. The expression profiles of these transporter genes were determined in three chlorantraniliprole-resistant strains: R1, R2, and HR, with a resistance ratio of 38.8, 110.4, and 249.6, respectively. CsABCA1, -D2, and -H2 were up-regulated in all resistant strains, and the trend in the transcript levels of all 47 CsABC genes fitted a descending curve from R1 to HR. Unexpectedly, CsABCF1, -G11 and -G12 were significantly down-regulated in HR. These results provide new insights into the roles of ABC transporters in chlorantraniliprole resistance in C. suppressalis.

      • KCI등재

        Opportunistic Routing for Bandwidth-Sensitive Traffic in Wireless Networks with Lossy Links

        Peng Zhao,Xinyu Yang 한국통신학회 2016 Journal of communications and networks Vol.18 No.5

        Opportunistic routing (OR) has been proposed as a vi-able approach to improve the performance of wireless multihopnetworks with lossy links. However, the exponential growth ofthe bandwidth-sensitivemobile traffic (e.g.,mobile video streamingand online gaming) poses a great challenge to the performance ofOR in term of bandwidth guarantee. To solve this problem, a novelmechanism is proposed to opportunistically forwarding data pack-ets and provide bandwidth guarantee for the bandwidth-sensitivetraffic. The proposal exploits the broadcast characteristic of wire-less transmission and reduces the negative effect of wireless lossylinks. First, the expected available bandwidth (EAB) and the ex-pected transmission cost (ETC) under OR are estimated basedon the local available bandwidth, link delivery probability, for-warding candidates, and prioritization policy. Then, the policiesfor determining and prioritizing the forwarding candidates is de-vised by considering the bandwidth and transmission cost. Finally,bandwidth-aware routing algorithm is proposed to opportunisti-cally delivery data packets; meanwhile, admission control is ap-plied to admit or reject traffic flows for bandwidth guarantee. Ex-tensive simulation results show that our proposal consistently out-performs other existing opportunistic routing schemes in providingperformance guarantee.

      • KCI등재

        Anti-tumor effect of novel amino acid Schiff base nickel (II) complexes on oral squamous cell carcinoma cells (CAL-27) in vitro

        Zhao Peng,Qiu Haiming,Wei Qiang,Li Yang,Gao Lei,Zhao Peiran 대한독성 유전단백체 학회 2023 Molecular & cellular toxicology Vol.19 No.2

        Background Oral squamous cell carcinoma (OSCC) is a common skin/oral malignant tumor. In recent years, advancements in the fi eld of medical technology resulted in signifi cant improvement in the treatment and management of OSCC. However, adverse reactions associated with the application of radiotherapy and chemotherapeutic drugs resulted in a low overall survival rate. Therefore, it is important to develop and explore alternative chemotherapy drugs, which can eff ectively treat OSCC, and clarify their mechanism of action. Objective The present study aimed to investigate the eff ect of three hexa-coordinated octahedral nickel (II) complexes, namely [Ni(sal- L -phe)(phen)(CH 3 OH)] CH 3 OH ( 1 ), [Ni(naph- L -phe)(phen)(CH 3 OH)] ( 2 ), and [Ni( o -van- L -phe)(phen) (CH 3 OH)] 5CH 3 OH ( 3 ), on proliferation, migration, and apoptosis of CAL-27 cells. Results The results of the study showed that complex 3 exhibited sensitive/signifi cant cytotoxicity toward CAL-27 cells, with an IC 50 value of 15.90 mΜ. Further, an assessment of the underlying mechanism showed that complex 3 could signifi cantly increase autophagy and reactive oxygen species (ROS) levels in CAL-27 cells. At the same time, it reduced mitochondrial membrane potential (MMP) in a dose-dependent manner. Additionally, complex 3 might act via inhibition of proliferation and migration of CAL 27 cells and induction of apoptosis, which was mediated via regulation of the expression of Bcl-2 family proteins in vitro. Conclusion The results of the study showed that nickel complexes could potently inhibit the growth of CAL-27 cells, which was mediated via mitochondrial dysfunction, intracellular ROS accumulation, and ROS-mediated DNA damage. Altogether, the fi ndings of the study would provide new leads for the designing and synthesis of novel metal drugs for OSCC.

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