인장하중을 받는 의사등방성 복합재 적층판의 피로손상

양광영,임경택,이동하,김택현,김인권 朝鮮大學校 機械技術硏究所 1999 機械技術硏究 Vol.2 No.1

The purpose of this work is to investigate fatigue damage of quasi-isotropic laminates under tensile loading in different directions. Low cycle fatigue tests of [O/-60/+60]s laminates and [+30/-30/90]s laminates were carried out. Materials systems used are AS4/Epoxy and AS4/PEEK. The fatigue damage of [+30/-30/90]s is very different from that of [O/-60/+60]s. The position of delamination generated at AS4/Epoxy and AS4/PEEK laminates were differentiated by the matrix difference that is, we suppose, the value of both G (critical energy release rate of mode-I) and G (critical energy release rate of mode-Ⅲ) difference. The experimental results are compared with the result obtained from the method of determining strain energy release rate components proposed by the authors.

Craves병 환자에서 백혈구와 갑상선 조직의 HLA-DR β 유전자 부위의 비교

양인명,우정택,팽정령,서광식,김성운,김영설,김광원,최영길 경희대학교 유전공학연구소 1989 遺傳工學論文集 Vol.1 No.-

정상 갑상선세포에서는 HLA-DR 항원이 발현되지 않았으나, 그레이브스병 환자의 갑상선세포 표면에는 HLA-DR 항원이 발현됨이 보고되어, 이러한 현상은 이 질환의 자가면역 기전에 중요한 역할을 하고 있을 것으로 생각되고 있다. 한편 최근 DR이나 DQ 유전자의 상부 159kb 이내에는 이들의 발현을 조절하는 유전자가 존재함이 알려져 있고, 이 부위의 구조적인 변화로 인하여 DR DQ 유전자의 발현을 유도하는 여러 가지 핵내 인자들과 interferon-r 와 같은 외부인 자들이 보고되고 있다. 그러나 그레이브스병에서 이들 유전자 부위의 구조적인 변화에 관해서는 아직 보고가 없다. 이에 본 연구자 등은 이러한 가능성 여부를 규명하고자 2명의 전형적인 그레이브스병 환자의 수술 우 얻어낸 갑상선 조직에서 RNA를 분리한 우 DR β유전자를 소식자로 northem blotting을 하여 mRNA의 발현을 관찰하였으며, 말초혈액 백혈구와 갑상선 조직으로부터 분리된 DNA를 EcoRI BamHI. HindⅢ PvuⅡ TaqI, PstI등의 6가지 제한효소로 소화한 후 DR β유전자를 소식자로 하여 RFLP 양상을 비교한 결과, 환자 모두에서 mRNA의 발현이 관찰되었으나, 환자 모두에서 6가지 제한효소에 의한 RFLP 양상이 동일하였다. 이러한 결과는 Graves병 환자의 DR 유전자의 발현에 있어서 이 유전자 부위의 구조적인 변화가 관여할 가능성이 적음을 시사하는 사실이라고 사료되나 향후 더 많은 예와 더 많은 제한효소를 이용한 주시가 필요할 것이다. The requirement for major histocompatibility antigen class Ⅱ molecules in the recognition of antigen by helper T cells suggests that the expression of class Ⅱ antigen may be important in the initiation and prolongation of immunopathology. HLA class Ⅱ antigenes are expressed on the surface of thyrocytes of the patients with graves disease. The increased expression of class Ⅱgene can be induced by trans acting factor such as interferon However the possibility of rearrangement of their regulatory genes has not been explored so far. We studied the mRNA expression in the thyrocytes of 2 patients with Graves' disease and compared the restriction fragment length polymorphism (RFLP) between thyroid and peripheral leukocyte DNA. The prominent expression of mRNA was observed in the thyroid tissues of all the two patients. But we did not find any difference in RFLP pattern in both patients. These results suggest the possibility that the rearrangement of the regulatory gene located in the upstream of DR- β gene can be a role in expression of DR antigen is less likely.

좁쌀약주 釀造를 위한 균주의 선발

梁榮澤,高正三,康順善 濟州大學校亞熱帶農業硏究所 1991 亞熱帶農業硏究 Vol.8 No.-

As the manufacturing techniques of foxtail millet wine, a traditional wine in Cheju island, has been transfered by person to person, basic studies on this are not carried out yet. There are many difficulties to industrialize it successfully without improvement of wine quality. The purposes of this study were to screen saccharifying mold strain and brewing yeast for foxtail millet wine-making. Optimum reaction conditions of crude enzyme of Aspergillus oryzae on saccharifying soluble starch were 55℃, pH 5.6, Saccharifying activity of crude enzyme was maintained 31.0~35.4% at 20~25℃, fermentation temperature, compared to optimum enzyme reaction conditions. Saccharomyces cerevisiae IAM 4274 was selected as brewing yeast strain for foxtail millet wine-making.

농촌지역 주민의 농기계에 의한 손상에 관한 연구

양한설,이태용,이동배,조영채,심운택 충남대학교 의과대학 지역사회의학연구소 1991 충남의대잡지 Vol.18 No.2

To find out the incidence rate of farm machinery injuries for rural residents and to analyse characterisitics of injuries, we surveyed 10,075 rural residents from six Myons in Chungnam province from January 1, 1990 to Deccember 31, 1990 The results were as follows: 1. 94.4%(101 persons) of the injured were male; 5.6%(6 persons) female. 2. The annual incidence rate per 1,000 rural residents was 10.6 persons, and the annual incidence rate per 100 farm machines was 11.2 persons. 3. The number of the injured were more in mountainous district than in plain distict 4. Injuries were occured throughout the year but predominantly in April and October. Farm machines which caused accidents were power tillers, combine, and a farm tractor in that order of frequency. 5. The injured part of body were fingers and arms, foot and legs, the chest, and the waist in that order of frequency. 6. Most of the injured had been to medical institution for treatment. 7. The major cause of injuries was personal factor.

심실 중격 결손에 의한 감염성 심내막염 환자의 치과치료

양정현,현홍근,김영재,김정욱,장기택,이상훈,한세현,김종철 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.3

당뇨병성 다발성 신경병증에 대한 Thioctic acid의 유효성 및 안정성에 관한 연구

박철영,김영설,오승준,우정택,김성운,양인명,김진우,최영길 대한당뇨병학회 2001 임상당뇨병 Vol.2 No.1

연구배경: 당뇨병성 신경병증은 당뇨병 환자에서 흔히 나타나는 합병증으로서 임상 증상은 가볍거나 없을 수도 있지만 많은 경우에 통증, 작열감, 이감각증이나 무감각증 등의 증상을 동반하지만, 이에 대한 명확한 기전이나 뚜렷한 치료방법이 없었다. 최근에 신경세포내 산화성 스트레스의 증가로 신경세포의 손상이 발생된다는 기전이 주목을 받으면서, 당뇨병성 신경병증 환자에게 항산화제인 thiotic acid를 사용하여 좋은 효과를 관찰한 논문들이 발표되었다. 이에 저자들은 한국의 당뇨병성 다발성 신경병증 환자에서 thiotic acid를 경구 투여 후에 신경병증에 의한 효과 및 안정성을 평가하였다. 방법: 모든 대상 환자에게 Thioctic acid 600㎎ 을 1일 1회 아침 식전 30분에 8주간 투여하여 당뇨병성 다발성 신경병증에 대한 TSS의 개선여부에 대한 임상적 유효성 및 이상반응, 내약성, 실험실적 지표의 변화를 통한 안정성을 관찰하였다. 결과: 치료시작 전에 관찰한 환자가 호소하는 증상은 통증이 가장 많았으며 무감각, 작열감, 이상감각 순의 빈도를 보였다. 통증, 작열감, 이감각증, 무감각증의 평균 TSS는 1차 방문시 5.8± 1.8, 2차방문시는 4.4±1.7, 3차 방문시는 3.1±1.1로 사용기판에 따라 통계학적으로 유의한 증상의 호전이 있었다. 또한 TSS의 개선 뿐만 아니라 통증, 작열감, 이감각증 및 무감각증 각각의 증상도 치료전과 치료 4주 후 및 치료 8주 후를 비교했을 때 통계학적으로 유의한 증상의 호전이 있었다. TSS가 1차 방문 시와 비교했을 때 3차 방문시에 30% 이상 개선되었을 때(1차 방문시에 TSS 4인 환자는 2점 이상 개선되었을때) 임상적으로 의미가 있는 반응으로 간주하고 계산한 반응률은 71.3%였다. 결론: 당뇨병성 다발성 신경병중 환자에 대해 항 산화제인 thioctic acid 600㎎ 경구 투여요법은 당뇨병성 신경병증의 증상완화에 유용하며, 안전한 것으로 사료된다. Background: The study was peformed to evaluate the efficacy and safety of oral treatment with the antioxidant α-lipoic acid (Thioctcid??) in diabetic patients with peripheral polyneuropathy. Methods: Thioctacid?? 600㎎ was orally administered once a day for 8 weeks in 61 diabetic patients with peripheral polyneuropathy. Neuropathic symptom(pain, burning, paresthesia, and numbness) were scored before, and of 4 and 8 weeks after treatment. In addition, neuropathy by the physician and patients at the end of treatment. The primary endpoint was the response role after 8 weeks treatment, defined as an improvement in the total symptom score of at least more than 30%. Results: Efficacy was evaluated among forty-four patients who had completely the study according to the protocol and safety was evaluated among all of 61 patients who had taken the study medication. The response rate after 8 weeks was 77.3%. The total symptom score was significantly decreased of 4-week, and further decreased of 8-week. All the individual scores for neuropathic symptom were also significantly reduced of 4-week and further decreased at 8-week. Conclusion: These finding indicate that oral treatment with thioctacid?? at a dose of 600㎎/day for 8 weeks will improve peripheral polyneuropathy in diabetic patients, without causing any serious adverse events.

졸-겔법에 의한 Mullite 코팅막의 제조 및 특성에 관한 연구

이용택,최영우,양중식 慶熙大學校 材料科學技術硏究所 1997 材料科學技術硏究論集 Vol.10 No.-

출발원료로 알루미늄 세크 부톡사이드(ASB)와 테트라 에톡시실란(TEOS)을 사용하는 졸-겔법에 의해 뮬라이트 조성의 졸 용액을 제조하고, 지지체 표면위에 침지 시간의 변화에 따라 코팅을 실시하였다. 그 결과 뮬라이트 결정화를 위해서는 1,300℃이상의 열처리 조건으로 균열 없는 뮬라이트 코팅막을 제조하는 것이 가능하였으며 침지시간에 따라 코팅막의 두께가 선형적으로 증가하고 평균 기공의 크기는 20∼30Å까지 기공 제어가 가능하였다. Optimal Mullite sol was synthesized by sol-gel process using Aluminium sec-butoxide(ASB), Tetraethoxy-silane(TEOS) and then, Mullite films were dip-coated with various holding time in sol bath and heat-treated at 1300℃ above for crystallization. The thickness of coated film increased linearly with holding time in sol bath and average pore size was controllable within 20-30Å.

임팩트시 테니스 라켓 재질의 차이에 따른 근전도 분석

윤양진,유국종,서국웅,정미라,강영택,이훈식,서국은 釜山大學校 附設 體育科學硏究所 1999 體育科學硏究所 論文集 Vol.15 No.-

The purpose of this paper is to select 7 male athletes and female athletes of high school, and to compare their active potential differences of upper arm muscles according to characteristic of a racket. the results obtained are as follows: 1. According to the accumulative distribution rate of racket material, graphite and wood material show better efficiency in case of brachio radialis muscle of male athletes, but the racket material shows no constant efficiency in brachii radialis muscle of female athletes. In case of flexor carpi radialis muscle, wood material provides better efficiency only for male athletes. In case of triceps brachii muscle, wood material gives better efficiency to males athletes and steel material gives better efficiency to females athletes. Especially in case of biceps brachii muscle, neither male nor female athletes are influenced by racket materials at impact. 2. In the muscle load rate according to racket material, wood has the highest muscle active potential and graphite has the lowest active potential. Therefore, graphite is thoght to be better in the efficiency of muscle load rate.

마이크로컴퓨터를 利用한 設備配置

朴永宅,梁正會 成均館大學校 科學技術硏究所 1987 論文集 Vol.38 No.1

This study presents a microcomputer program for a facility layout that uses the relationship chart which represents interdepartmental relationships. The program presented here is written in BASIC language. The program uses the following three-stage algorithms: (1) Selection of placement order 1) Select a department having the largest total closeness rating. 2) Search for a department with a interdepartmental interation of the highest closeness rating with the last selected department. If the rating is higher than minimal acceptable closeness rating, return to 2). Otherwise, search for one of the unselected department having the largest total closeness rating, return to 2). (2) Placement pattern Department placement starts at the center of the screen and spirals outward until the layout is established. (3) Layout scoring The distance from each department centroid to the others is multiplied by the corresponding closeness rating and summed to give the total score. The presented algorithm was tailored after that of Gaston, but our algorithm improved the Gaston's as follows: 1) The first selection of a department was based on the total closeness rating instead of random selection. 2) The possible distance measures are rectilinear, euclidean and squared euclidean distances instead of the rectlinear distance alone. 3) Preassigned departments such as aisles, stairwells, etc. can he located in advance.

전해응집공정을 이용한 염색폐수의 처리

이용택,한승우,조영개,이현문,김태근,손인식,양병수 한국환경과학회 2000 한국환경과학회지 Vol.9 No.4

This research studied the characteristics and applicability of electrocoagulation using aluminium electrode for the color and COD removal in textile wastewater. Electrocoagulation reactor used two different electrode, Fe and Al, since in the general chemical wastewater treatment, aluminium and ferrous salts were used as coagulants. Aluminium electrode showed higher removal efficiency of color and COD than ferrous electrode did. The COD and color removal efficiency improved at the 0.192A/dm^2 current density. Thus, the electrocoagulation process with bipolar aluminium electrode showed better efficiency in the decolorization and COD removal rate of textile wastewater effluent than custom coagulants did.