뇌경색증의 급성기에 발생한 변비에 대한 연구

최윤이,김소이,김성은,정혜경,김태헌 이화여자대학교 의과학연구소 2015 EMJ (Ewha medical journal) Vol.38 No.1

Objectives: The prevalence of constipation is high after stroke. Multiple factors such as long-term bed-ridden status, comorbidity, medical illnesses are combined in this condition. However, the change of bowel movement during the early stage of stroke remainsuncertain. Methods: Patients with first stroke who admitted in a single institute from 2008 to 2009 were reviewed retrospectively and 36 patients were enrolled. As a control group, 47 consecutive orthopedic patients needing bed rest without surgery in the same period were enrolled. Data of stroke associated factors, frequency of BM (bowel movement) during 5 weeks, use of gastrointestinal medications, and outcomes were collected from the medical records. Results: The cumulative incidence of decreased (<3/week) and severely decreased BM (<1/week) were 80.6% and 69.4% in stroke patients and 53.2% and 14.9% in control group (P<0.05). The cumulative incidence of increased BM (>3/day) was 38.9% in stroke and 14.9% in control group. In acute stroke, 58% of patient showed severely decreased BM in first week, and the proportion was rapidly decreased below 15% from second week. However, laxative use increased with hospital days. The occurrence of severely decreased BM in stroke patients was associated with National Institutes of Health Stroke Scale (NIHSS; P=0.004). Severely decreased BM was not associated with poor outcomes including death, morbidity, and stroke recurrence. Conclusion: Decreased BM is common in acute stroke. The occurrence of severely decreased BM is associated with NIHSS. However, the severe manifestation occurred mainly in the first week, and considered to be well controlled by laxatives.

평방근 정보필터를 이용한 상관된 측정잡음을 갖는 기동표적의 추적을 위한 상호간섭다중모델 기법

권성숙,김경연 濟州大學校 工科大學 産業技術硏究所 1998 尖端技術硏究所論文集 Vol.9 No.1

In tracking a maneuvering target by a rader system, the measurement noise is significantly correlated when the measurement frequency is high. In this paper, we describe an efficient interacting multiple model(IMM) approach for tracking a maneuvering target with correlated measurement noise based on the square root information filter(SRIF). The SRIF is employed instead of conventional Kalman filter since it exhibits more efficient features in handling the decorrelation process and improved numerical characteristics. The Monte Carlo simulations for the maneuvering target are provided to demonstrate the enhanced tracking performance of the proposed algorithm.

소규모사업장 보건관리기술지원사업 지원여부에 따른 사업장내 의사소통 비교

정최경희,박혜숙,김정연,이경용,현성민,오지영,김수근,김현주,하은희 이화여자대학교 의과대학 2003 EMJ (Ewha medical journal) Vol.26 No.2

목적: 소규모사업장 보건관리기술지원사업 지원여부에 따라 사업장내 위험의사소통채널이 마련되었는지와 이 채널이 기능을 하는지, 그리고 의사소통채널마련과 사업장내 위험의사소통 활성화의 기본적이고 중요한 배경이 되는 사업주의 산업보건에 대한 관심이 차이가 있는지에 대해 살펴보고자 하였다. 방법: 서울, 안산, 대전, 광주, 포항 지역에서 보건관리기술지원사업을 받은 사업장과 받지 않은 사업장을 대상으로 비례층화무작위표본추출법을 사용하여 추출한 후 1991년 12월 6일부터 10일간 우편설문조사를 실시하였다. 설문대상은 각 사업장의 남녀 각 1명, 보건업무담당자, 사업주였으며, 설문내용은 사업장 및 응답자의 일반적 특성 및 사업장내 위험의사소통이었다. 설문에 응답이 온 463개 사업장의 자료를 자료처리하여 총 228개 사업장(단해년도지원 사업장 189개, 연속2년지원 사업장 13개, 비지원사업장 26개)을 대상으로 분석하였다. 결과: 사업장내 의사소통에 대한 단변량분석에서는 보건업무 담당자의 선정여부만이 통계적으로 유의한 차이가 있었다. 소규모사업장 보건관리기술지원사업을 지원받지 않은 사업장과 지원받은 사업장의 사업장내 위험의사소통을 비교하기 위한 로지스틱회귀분석 결과, 모든 항목에서 통계적으로는 유의한 차이를 보여주지 않았다. 그러나 사업주의 관심(OR ; 1.63, 95% CI ; 0.38~7.01)과 보건업무담당자의 선정(OR ; 3.67, 95% CI ; 1.00~13.44) 및 결정권한(OR ; 1.48, 95% CI ; 0.25~8.91), 사업주의 산업보건문제 소통(OR ; 3.07, 95% CI ; 0.81~11.71), 보건업무담당자의 정보요청경험(OR; 4.48, 95% CI ; 0.97~20.57)에서는 지원받지 않은 사업장에 비해 지원받은 사업장에서 교차비가 증가하는 양상을 보여주었다. 반면 노동자의 산업보건문제 소통가능성여부는 오히려 교차비가 0.53(95% CI ; 0.11~2.44)로 감소하는 경향을 보여주었다. 결론: 소규모사업장 보건관리기술지원사업을 의사소통의 측면에서 평가해보면, 사업주나 보건업무담당자에게는 다소 효과가 있었지만 노동자가 지속적으로 참여할 수 있도록 의사소통문화를 바꾸어내는 데에는 한계가 있었다. 개선을 위해서는 노동자 중심의 접근 프로그램의 개발 및 시행이 시급하다 할 수 있다. Objectives :This study was to evaluate the effectiveness of the government-funded subsidized occupational health program for small-scale enterprises(GSOHP_SSE) by occupational health com-munication in workplace. Methods : We sampled the 1,835 enterprises of study by proportional stratified random sampling among industries of supported and not supported by GSOHP_SSE in Seoul, Ansan, Daejeon, Kwang-joo and Pohang. Information on the general characteristics of enterprises and respondants and occupational health communication in the workplace was collected on self-reported questionnaires by post-survey between December 6 and 15 in 2001. We received answers from 463 enterprises and analyzed 228 enterprises through data-cleaning by logistic regression to evaluate effectiveness of GSOHP-SSE about occupational health communication in the workplace. Results : By multiple logistic regression analysis, GSOHP_SSE turned out not to be statistically significant factor in all dependent variables about occupational health communication in the work-place. The concern of owner(odds ratio (below OR) ; 1.63, 95% confidence interval(below 95% CI) ; 0.38-7.01), formation(OR ; 3.67, 95% CI ; 1.00-13.44) and empowerment(OR ; 1.48, 95% CI ; 0.25-8.91) of health manager, request about occupational health problem of health manager(OR ;4.48, 95% CI ; 0.97-20.57) and occupational health communication of owner (OR ; 3.07, 95% CI ; 0.81-11.71) had the trend increasing OR in the industries supported GS-OHP_SSE relative to the industries not supported. But in recognition of possibility on occupational health communication of laborers, OR of GSOHP_SSE was decreased in 0.53(95% CI ; 0.11-2.44). Conclusions: This study found that the GSOHP_SSE was some effective to the side of employer and health manager, but had a limitation about change of communication culture useful to the laborers. We suggested the laborer-centered health training programs or the empowerment-based health training programs for effective occupational health management in the workplace.

광촉매를 이용한 Humic Acid 광분해시 공존물질이 광분해에 미치는 영향

류성필,현경자,오윤근 한국환경과학회 2004 한국환경과학회지 Vol.13 No.3

This study aimed at improving the TiO₂ photocatalytic degradation of HA. A set of tests was first conducted in the dark to study the adsorption of HA at different coexisting material concentration. Adsorption rate increased with adding cation ion but decreased with adding bicarbonate ion. The photodegradation of HA in the presence of UV irradiation was investigated as a function of different experimental condition : initial concentration of HA, TiO₂ weight, pH, air flow rate and coexisting material. It was increased either at low pH or by adding cation ion. The increase of cation strength in aqueous solution could provide a favorable condition for adsorption of HA on the TiO₂ surface and therefore enhance the photodegradation rate. It was found that bicarbonate ions slowed down the degradation rate by scavening the hydroxyl radicals.

평방근 정보필터를 이용한 미지의 측정 바이어스를 갖는 시스템에 대한 적응추정기의 설계

권성숙,김경연,김창일,김경식 濟州大學校工科大學産業技術硏究所 1996 尖端技術硏究所論文集 Vol.7 No.2

In this paper, we present an adaptive estimator for tracking of a maneuvering target containing unknown or randomly switching biased measurements using square root information filter(SRIF). The SRIF is employed instead of conventional Kalman filter since it exhibits more efficient features in handling the unknown measurements bias and improved numerical characteristics. Computer simulations for a system with unknown bias are carried out to show the adaptability and tracking performance of the proposed algorithm.

평방근 정보필터를 이용한 상관된 측정잡음을 갖는 기동표적의 추적을 위한 상호간섭다중모델 기법

권성숙,김경연 濟州大學校 産業技術硏究所 1998 산업기술연구소논문집 Vol.9 No.1

In tracking a maneuvering target by a radar system. the measurement noise is significantly correlated when the measurement frequency is high. In this paper. we describe an efficient interacting multiple model(IMM) approach for tracking a maneuvering target with correlated measurement noise based on the square root information filter(SR1F). The SRIF is employed instead of conventional Kalman filter since it exhibits more efficient features in handling the decorrelation process and improved numerical characteristics. The Monte Carlo simulations for the maneuvering target are provided to demonstrate the enhanced tracking performance of the proposed algorithm.

줄넘기 運動의 有ㆍ無酸素的 運動强度 역치수준 設定을 위한 硏究

盧成圭,윤재원,김두경,하명수,장세원,윤중현 江原大學校附設體育科學硏究所 1987 江原大學校附設體育科學硏究所論文集 Vol.- No.12

The purpose of this study was the level of Aerobic-Anaerobic exercise intensity according to Rope skipping frequency by the skipping type at different age group(Middle, Junior high school and collegean). Types of Rope skipping(Jump, Leap and Double jump) with 100 rounds per min(5min), 120 rounds per min (5min) and max round frequency were tested by 120 volunteer untrained men and women students (forty middle school, forty high school and forty collegean) form Oct. 10. 1987 to No V.5. 1987. The results are showed at the skip intensity of 120 rounds per min. was higher than that of 100 rounds per min. at all skipping types, and men students showed less HR than women students. From the testing result, Double Jump was Considered as Anaerobic Exercise, Tean Jump was determined the strongest Aerobic exercise, and Jump or Leap were moderate Aerobic exercise. Recommending round frequency per min from multiple regression were follows. ----------------------------------------------------------------------------- Type Age 15 18 21 duration Sex ----------------------------------------------------------------------------- Jump man 127☆ 147 167 5min woman 113 126 140 5min ----------------------------------------------------------------------------- D.Jump man 137 169 211 2min woman 126 155 183 2min _____________________________________________________________________________ ☆ Round numbers per min

고콜레스테롤 혈증 환자에서 Cerivastatin(LIPOBAY, 의과학연구소)의 임상효과 및 안전성에 관한 연구

박성훈,김미연,정수진,이영숙,박창한,변은경,전성희 梨花女子大學校 醫科大學 醫科學硏究所 2001 EMJ (Ewha medical journal) Vol.24 No.3

목적 : Cerivastatin(LIPOBAY)은 최근에 개발되어 사용되기 시작한 HMG-CoA 환원효소 억제제로서 저용량으로 탁월한 콜레스테롤 강하효과를 보이는 약물이다. 저자들은 Cerivatatin(LIPOBAY)의 혈중 콜레스테롤 강하효과를 평가하고 약물의 안전성을 평가하기 위하여 본 연구를 시행하였다. 방법 : 고콜레스테롤혈증 환자 37명(남자 13명, 여자 24명)을 대상으로 하였다. 대상환자는 2주간의 저콜레스테롤 식이 후에도 혈청 콜레스테롤이 240㎎/㎗이상이거나, 관상동맥질환이 있는 환자는 혈청콜레스테롤이 220㎎/㎗이상인 경우 cerivastatin 0.4㎎을 8주간 복용하도록 하였다. 임상적 관찰과 검사실 검사(간기능검사, 일반혈액검사, 혈청지질검사)는 투약개시 후 4주 및 8주 후에 시행하였다. 결과 : Cerivastatin 0.4㎎을 4주간 투여한 후 측정한 LDL 콜레스테롤, 총콜레스테롤, triglyceride, 및 HDL 콜레스테롤은 각각 38%, 28.8%, 11.6% 및 7.8% 감소하였다. 총콜레스테롤/HDL 콜레스테롤 비 및 LDL/HDL비는 각각 20.8% 및 31.1% 감소하였다. 투약 8주후에 측정한 검사소견은 4주후에 비해 유의한 변화를 보이지 않았다. 한명의 환자(2.7%)에서 간기능 검사상 AST, 및 ALT의 지속적인 상승으로 투약을 중지하였다. 결론 : Cerivastatin 0.4㎎/day는 혈청콜레스테롤을 효과적으로 감소시켰으며 심각한 부작용은 볼 수 없었다. 따라서 적극적으로 LDL콜레스테롤을 낮출 필요가 있는 고콜레스테롤혈증 환자에서 cerivastatin은 효과적이고 안전한 약물이라고 생각된다. Objectives : Cerivastain(LIPOBAY) is recently developed HMG-CoA reductase inhibitor which is effective in lowering serum cholesterol levels at microgram does. We evaluated the clinical efficacy and safety of cerivastatin(LIPOBAY) in patients with hypercholesterolemia. Method : Thirty-seven patients(male : 13, female : 24) with hypercholesteolemia defined as baseline serum total cholesterol ≥240㎎/㎗, or ≥220㎎/㎗ in patients with known coronary artery disease were included for this study. After 2 weeks of low cholesterol diet, if the serum total choesterol level meet the criteria, cerivastain 0.4㎎/day was prescribed for 8 weeks. Clinical follow-up and laboratory tests were performed 4 weeks and 8 weeks after medication. Results : After 4 weeks of cerivastain 0.4㎎/day treatment, low density lipoprotein(LDL) cholesterol decreased 38% and total cholesterol decreased 28.8% from baseline. Triglyceride decreased 11.6%, and high density lipoprotein(HDL) cholesterol decreased 7.8% from baseline. Total cholesterol/HDL ratio decreased 20.8% and LDL/HDL ratio decreased 31.1% from baseline. After 8 weeks of treatment, no further significant changes were noted compared with the values at 4 weeks. Cervastatin was discontinued in one patient(2.7%) due to continuous liver enzyme elevation. Conclusion : Cerivastatin 0.4㎎/day is effective in lowering serum cholesterol levels without significant adverse reactions. Cerivastatin is effective and safe for patients with hypercholesterolemia who needs aggressive LDL cholesterol lowering.

적응추정기를 이용한 강의 수질 감시 시스템 설계

김창일,권성숙,김경식,김경연 濟州大學校 情報通信硏究所 1998 情報通信硏究所論文集 Vol.1 No.-

An adaptive estimator to estimate the water quality in a river under unknown biased measurements environment is developed. In modeling the unknown measurement bias, it is assumed that the bias sequence is governed by semi-Markov process. By incorporating the semi-Markov probability concepts into the Bayesian estimation theory. an effective adaptive estimator which consists of parallel Kalman-type filters is obtained. Computer simulation results for the multiple-reach river system show that the proposed adaptive estimator have good estimation performance in spite of the unknown randomly switching measurement bias.

동맥경화에 의한 하지 허혈증 환자에서 Subintimal Angioplasty의 효과 : 단기 추적 결과를중심으로

윤상섭,허윤정,최승혜,박종경,이성,송경섭 대한혈관외과학회 2003 Vascular Specialist International Vol.19 No.2