인슐린 비의존형 당뇨병 환자에서 당뇨병성 신증의 지표로서 혈청과 요Ⅳ형 collagen의 의의

장태종,최병진,반금진,노영호,김소연,조민구,이권전,김윤권 대한신장학회 1996 대한신장학회잡지 Vol.15 No.4

부하순환 하에서 제V급 복합레진 수복물의 미세변연누출에 대한 재접착제의 효과에 관한 연구

윤연희,김영재,김정욱,장기택,이상훈,김종철,한세현 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.3

저점도의 레진을 복합레진 수복물 위에 도포하는 것은 미세누출방지와 변연 완전성(integrity) 유지를 위한 한 방법이다. 하지만 장기간 관찰하면, 수복물은 저작압에 의한 영향을 받게 되는데, 저점도의 레진으로 수복물 변연부를 재접착(rebonding)하였을 때 저작압에 의한 응력에 견디면서 계속하여 수복물에 긍정적인 영향을 주는지에 대한 연구는 미흡한 실정이다. 본 연구는 부하순환(load cycling) 하에서 제Ⅴ급 수복물의 미세변연누출에 대한 재접착제 (rebonding agent)의 효과를 알아보고자 하였다. 40개의 건전한 소구치의 협면에 제Ⅴ급 와동을 형성하고 제조사의 지시대로 광중합복합레진으로 수복하였다. 20개씩 무작위로 나누어 표면전색을 하지 않는 Ⅰ군과 표면을 산부식 후 재접착한 Ⅱ군으로 설정하였다. 열순환 후 각 군에서 10개씩의 하위군 (A군=No load cycling군, B군=Load cycling군)으로 나누어 이중 B군의 시편에 1 Hz의 속도로 수직력이 4-100까지 100,000회의 부하순환을 가하였다. methylene blue용액에 침윤시켜 변연의 미세누출릉도를 평가하여 다음과 같은 결과를 얻었다. 1. 교합변연에서는 재접착과 무관하게 유의한 차이가 없었다(ⅠA-ⅡA군, ⅠB-ⅡB군) (p>0.05). 2. 치은변연의 경우는 부하순환을 하지 않은 군의 경우 재접착을 한 군(ⅡA군)이 재접착을 하지 않은 군 (ⅠA군)에 비해 더 적은 미세누출결과를 보였다(p<0.05). 3. 치은 변연에서 부하순환을 시행한 군의 경우에는 재접착을 한 군(ⅡB군)과 재접착을 하지 않은 군 (ⅠB군)과 유의차가 없는 비슷한 미세누출의 결과를 보였다(p>0.05). One clinical technique recommended f3r improving marginal integrity is "rebonding" or application of unfilled resins to the surface of composite restoration. But continuously the restorations are affected with occlusal load. There is room for doubt that the rebonding agent has the positive effect on microleakage in spite of the stress generated by the occlusal load. This study determined the effect of rebonding on microleakage of Class Ⅴ resin composite restorations under load cycling. Class Ⅴ cavities were prepared on the buccal surface of 40 sound extracted premolars and restored with a hybrid light-cured resin composite according to manufacturers' directions. They wert randomly divided into two groups consisting of 20 samples a control(group Ⅰ), without surface sealing, and the other group (group Ⅱ) in which margins were etched and rebonded. After thermocycling, each of groups was divided into subgroups (group A, B), and load cycling(total 100,000 cycles with 4-100N load at a rate of 1 Hz) were applied on the group B. Assessment of microleakage utilized methylene blue dye penetration. The following results were obtained : 1. In the occlusal region, no significant difference was noted in the scores regardless of whether or not the rebonding agent was used (group ⅠA-ⅡA, ⅠB-ⅡB) (p>0.05). 2. In the cervical region, the control group with rebonding (group ⅡA) showed the better result than the group without rebonding (group ⅠA) (p<0.05). 3. In the cervical region, the rebonded group with load cycling(group ⅡB) showed similar results to the groupf·ithout rebonding(group ⅠB) and no significant difference was noted(p>0.05).

保存血의 腐敗産物에 依한 에틸알콜 生成濃度에 關한 硏究(Ⅱ)

張成吉,金英雲,柳在薰,權五星,朴世延 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

항진균물질을 생산하는 Streptomyces fimbriatus AF21-3의 분리 및 동정

장주현,김정완,이우윤,윤영준,이경림,김승곤,이태수 인천대학교 2000 基礎科學論文集 Vol.11 No.1

Actinomycetes were isolated from soil to find new antibiotics. An active antimicrobial compound was isolated from the culture filtrate of Actinomycetes AF 21-3. The Actinomycetes strain which showed strong antifungal activity against Candida tropicalis and Microsporum gypseum was identified as Streptomyces fimbriatus and named as Streptomyces fimbriatus AF 21-3.

MOS 캐패시턴스를 구하기 위한 알고리즘

장윤영,홍창희 동아대학교 공과대학 부설 한국자원개발연구소 1991 硏究報告 Vol.15 No.1

The MOS capacitor is one of the most useful devices for basic characterization of semiconductor material and interface properties. Oxide thickness, substrate impurity profiles, interface state distribution, and impurity energy levels are just a few of characteristics which capacitance-voltage(C-V) measurements help quantify. while closed-form analytic expression for the C-V characteristics of MOS devices with uniform substrate doping concentration are well known, similar expression for nonuniform impurity profiles cannot be obtained. This paper presents a computationaly efficient numerical method for the evalution of equilibrium C-V characteristics of one-dimensional MOS capacitor whose substrate has the arbitrary doping profile. A computer program MOSCAP is coded in Microsoft FORTRAN Ⅴ, accurately calculates MOS C-V profiles from 50k to 350k.

生體血의 保存環境과 腐敗産物에 依한 血中알콜濃度變化에 關한 硏究

張成吉,金英雲,柳在薰,吳世珍,權五星,朴世延 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

상악 측절치의 치내치에 대한 증례보고 : REPORT OF 2 CASES

윤석희,이재천,김영재,장기택,한세현,김종철 大韓小兒齒科學會 2004 大韓小兒齒科學會誌 Vol.31 No.3

치내치(dens invaginatus)는 치아 발생 과정 중 경조직이 석회화되기 전에 법랑질 상피가 함입되어 생기는 치아 기형이다. 치내치는 함입된 정도에 따라다양한 형태학적 변이를 보이는데 이러한 기형은 미생물이 침입할 수 있는 통로가 될 수 있어 치수조직의 괴사와 치근단 농양 또는 치은 농양의 원인이 된다. 이러한 경우 근고나의 복잡한 해부학적 형태 때문에 근관 치료가 매우 어렵다. 본 증례는 상악 좌측 측절치의 동통을 주소로 내원한 두 명의 환아들에 관한 것이다. 첫 번째 증례는 수산화 칼슘제재를 이용한 근관치료를 시행하여 양호한 결과를 얻었고 두 번째 증례는 치아를 발거하였다. 발거된 치아는 미세전산화 단층촬영을 이용하여 해부학적 형태를 살펴보았기에 보고하는 바이다. Dens invaginatus is a malformation of tooth resulting from an infolding of the enamel epithelium during tooth development. This malformation shows a broad spectrum of morphologic variations. This invagination frequently allows the entry of irritants and microorganism, which usually lead to necrosis of the adjacent pulp tissue and then to periapical or periodontal abscess. Root canal treatment of such tooth is often difficult because of the unusual form and complicated pulpal space. This article reports 2 cases of dens invaginatus in maxillary lateral incisors. The first case was successfully treated with Ca(OH)₂. In the second case, involved tooth was extracted and this extracted tooth was observed using the micro-computed tomography.

한랭노출과 고혈압의 연관성

장태원,김윤규,윤동영,이창희,홍영습,신해림,정갑열,김준연 大韓産業醫學會 2001 대한직업환경의학회지 Vol.13 No.4

Objectives : This study was carried out to suggest preventive methods for hypertension in cold-exposed workers. Methods : In 11 refs·iteration industries, 68 workers working in refrigerated areas more than one time per day were selected as the exposed group, and 68 workers not exposed to cold were selected as the control group. We interviewed the subjects with a questionnaire covering occupational history, and conducted clinical and laboratory tests including measurements of blood pressure and core temperature. Results : The systolic blood pressure in the exposed group(130.0±13.3 mmHg) was significantly higher than that recorded In the control group(118.3±12.1 mmHg), as was the diastolic blood pressure in the exposed group(82.7±8.5 mmHg) versus the control group(77.4±8.7 mmHg). The core temperature in the exposed group(36.1±0.7℃) was significantly lower than that experienced in the control group (36.4±0.5℃). In logistic regression analysis, age, cold exposure severity and milk intake were significant variables, with odds ratios of 5.204(95 % CI 1.440∼18.812), 2.674(95 % CI 1.080∼6.618), and 0.364(95 % Cl 0.141∼0.942) , respectively. Conclusions : Our study suggests that cold-exposed workers have higher a higher risk of hypertension, and that their core temperature is lower. Risk factors affecting hyper-tension of cold-exposed workers include age, cold exposure severity and milk intake. For the prevention of hypertension, cold-exposed workers should minimize cold-exposure time as much as possible.

肉鷄後期飼料의 給與時期가 鷄肉의 理化學的 性質에 미치는 影響 : 貯藏期間別에 따른 pH, 保水性 및 軟度의 變化 Changes in PH, Water Holding Capacity and Tendness

尹東根,鄭場龍,張判亨,朴久富 진주산업대학교 1985 論文集 Vol.23 No.-

後期飼料를 3주령부터 조기에 급여한 broiler肉의 흉심부, 대퇴부 및 근위를 냉장온도(4℃)에서 저장한 후 저장시간의 경과(0,8,48,96,168시간)에 따른 pH, 보수성 및 軟度의 變化를 경시적으로 分析한 結果는 다음과 같다. 1. pH의 變化를 보면 各 시험구의 部位間에는 통계적인 유의성이 없었고 저장시간의 경과에 따른 경시적인 차이를 보면 도살직후 6.68~6.77로 나타났으나 저장후 8시간이 경과될 때 pH가 5.67~5.76으로 급격히 저하되었으며 48시간이 경과되면서 부터 상승하여 이후는 서서히 회복되었다. 2. 保水性의 變化를 보면 各 시험구의 부위간에는 통계적인 유의성이 없었고 저장시간의 경과에 따른 경시적인 차이를 보면 도살직후 65.9~67.4%로 나타났으며 저장후 8시간이 경과될 때 흉심, 대퇴, 근위 모두 급격히 감소되었으나 48시간이 경과되면서 부터 증가되어 168시간 이후부터는 서서히 회복되었다. 3. 軟度의 變化는 흉심과 대퇴部位 근육에 비하여 근위가 매우 낮았고 저장기간의 경과에 따른 變化는 도살직후에 비하여 8시간이 경과될때 현저히 낮아진 후 48시간까지는 서서히 감소된후 168시간 부터는 회복되는 결과였다. 4. pH, 保水性 및 軟度等의 물리적인 性質을 究明한 바 각 처리區間에 통계적인 유의성은 인정되지 않았으며 3주령 부터 후기사료를 급여한 결과 pH, 보수성 및 연도 等에 영향을 미치지 않았다. This experiment was conducted to investigate the changes in pH, water holding capacity and tenderness as the passage of storing time(0,8,48 168 hr) after storing at 4℃ the meat cut 3 parts of leg, breast and gizzard of broiler-Hubbard at 9weeks fed early finisher diet from 3 weeks. The results obtained were summarized as follows: 1. In the pH changes during postmorterm storage, there were nonsignificant differences(p>0.05) between treatments. In the pH changes as storage time passed, pH immediately after slaughtering was 6.68 to 6.77 and the lowest with 5.67 to 5.76 when storage time passed 8hours and pH was again high after storage time passed 48 hours. 2. Though the changes in water holding capacity were nonsignificant differences(p>0.05) between leg, breast and gizzard meat. There was lightly difference as the storage time passed, pH immediately after slaughtering was 65.9 to 67.4%, pH of leg, breast and gizzard was decreased as the storage time passed 8 hours, but was increased as the storage time passed 48 hours. 3. The changes in tenderness were lower in gizzard in leg than breast. It was lower in the storage of 8 hours than immediately after slaughtering. After pH was gradually decreased to the storage of 48 hours, again increased from the storage of 168 hours. 4.PH, water holding capacity and tenderness analyzed in this experiment were non significant differences(p>0.05) between treatments and there was not the effect of finisher diet on the physical properties.

황색포도상구균 신속 검출용 간이 진단키트

김기영,박샛별,문지혜,이상대,이새롬,장윤정 충남대학교 농업과학연구소 2013 농업과학연구 Vol.40 No.2

This study was performed to develop a rapid test kit for pathogenic Staphylococcus in various samples. The rapid detection kit has been fabricated based on nitrocellulose lateral-flow strip. Colloidal gold and Staphylococcus antibodies were used as a tag and a receptor, respectively. Manually spotted Staphylococcus antibody and anti-mouse antibody on the surface of nitrocellulose membrane were used as test and control lines, espectively. Feasibility of the rapid kit to detect Staphylococcus aureus in samples were evaluated. The intensity of the color of the tes line started to increase with the samples in which higher concentration of the cells were contained. The sensitivity of the sensor was 106 cfu/mL Staphylococcus spiked in PBS. Also, the rapid test kit could detect 105 cfu/mL of Staphylococcus in chicken meat extract.