빌라조경 설계사례에 관한 연구 : Case Study of Jang-chung Dong Villa

김동찬,이윤수,유재설,박익수,임동민,임상재 경희대학교 부설 디자인연구원 1998 예술· 디자인학연구 Vol.1 No.1

The goal of this study is to propose a plan for the Jang-Chung Dong Villa. This Villa is located on Jang-Chung Dong Jung-Gu, Seoul. And, this place is where high-class residential area. This Site area covers about 1925.6m². This base idea of this plan is to provide a community of dwelling houses with identity and amenity in outdoor spaces in order to create the high-class environment of outdoor spaces. Design principles are established as follow; to make spaces for flexibility in the garden related activities, to provide many chances to contact with nature, and to feel pride in the villa life.

Abnormal differentiation of regulatory T cells and Th17 cells induced by perinatal bisphenol A exposure in female offspring mice

You‑dan Dong,Liang Gao,Feng‑juan Wu,Ren Lin,Yuan Meng,Li‑hong Jia,Xiao‑fei Wang 대한독성 유전단백체 학회 2020 Molecular & cellular toxicology Vol.16 No.2

Background Bisphenol A (BPA) is an environmental estrogen widely exposed to human beings, and there are more studies on its reproductive toxicity, endocrine disruption and neurobehavioral disorders. Recent few studies have found that BPA has immunotoxicity, and its mechanism is not clear. Therefore, the effects of BPA on immune system have attracted extensive attention. The aim of this study was to investigate the effect and mechanism of perinatal exposure to BPA on regulatory T cells (Treg) and Th17 cells in female offspring mice. Methods Twenty-one pregnant C57BL/6 mice were randomly divided into three groups: a control group, low-dose BPA (0.2 μg/mL) and high-dose BPA (2.0 μg/mL) exposure group. All received BPA exposure via drinking water from gestational day 6 to the end of lactation. Female offspring were fed a normal diet and drinking water for 1 month. The percentages of Treg and Th17 cells, the levels of Foxp3 and RORγt protein and IL-17 and TGF-β from spleen tissue or blood were measured in female offspring. Results The percentage of Treg cells and levels of Foxp3 protein decreased, while the percentage of Th17 cells and levels of RORγt protein increased, which showed a dose–effect relationship. The levels of serum TGF-β were significantly lower and the levels of serum IL-17 were statistically higher in BPA-exposed female offspring compared with controls (P < 0.05 or P < 0.01). But there were no statistical difference in the levels of serum TGF-β and IL-17 between 0.2 μg/mL and 2.0 μg/ mL BPA groups (P > 0.05). Conclusion BPA exposure during pregnancy and lactation could cause abnormal differentiation and function of Treg and Th17 cells in female offspring mice, which was associated with down-regulated Foxp3 and up-regulated RORγt protein, respectively. Our findings indicated that BPA exposure during early development may play an important role in the development of autoimmune diseases later.

유동인구 분석을 통한 폭염 긴급재난문자의 효과 분석

홍유정(You-Jeong Hong),정진도(Jindo Jeong),김우식(Woosik Kim),윤동근(Dong Keun Yoon) 한국방재학회 2023 한국방재학회논문집 Vol.23 No.6

Heatwave emergency alert messages (EAM) not only provide objective information on heatwave occurrences but also include behavioral guidelines, such as avoiding outdoor activities or going out to respond to heatwaves and minimize damage. To investigate the EAM's effectiveness, we analyzed the changes in the floating population during 2021 using Seoul dong-unit and hourly location-based mobile big data. We also examined what socioeconomic and physical environmental characteristics could cause differences in the effectiveness, focusing on the fact that EAM may have different effects depending on regional factors. The findings revealed a notable reduction in the overall floating population of Seoul, ranging from 0.1 to 3.4%. When examined by region, an average decrease of 2.4 to 5.6% was observed, indicating the different effects of EAM by region. Further analysis of regional characteristics highlighted that areas with low EAM effectiveness were characterized by a lower ratio of senior residents, higher employment concentration, and higher accessibility to public transportation. Additionally, the number of household members, gender distribution, average age, and presence of green spaces can contribute to the gap in the effectiveness of EAM between regions. 폭염 긴급재난문자는 폭염 대응 및 피해 최소화를 위하여 폭염 발생에 대한 객관적인 정보 제공뿐만 아니라 야외활동 자제 또는 외출 자제 등의 행동 지침 내용을 포함하고 있다. 본 연구는 폭염 긴급재난문자의 효과를 분석하기 위해 2021년 폭염기간을 대상으로 서울시 동-시간 단위의 위치기반 모바일 빅데이터를 활용하여 유동인구 변화를 분석하였다. 또한 지역의 사회경제적⋅물리환경적 특성에 따라 폭염 긴급재난문자의 효과가 다르게 나타날 수 있는데 주안을 두고 어떠한 특성이 긴급재난문자의 효과 차이를 발생시킬 수 있는지 검토하였다. 분석 결과, 서울시 전체 유동인구는 폭염 긴급재난문자로 인해 0.1~3.4%의 범위에서 감소하였다. 한편, 지역별로는 평균적으로 2.4~5.6% 범위에서 감소하였으며, 긴급재난문자가 지역마다 효과가 다르게 나타나고 있음을 확인하였다. 긴급재난문자의 효과가 큰 지역과 작은 지역 간의 차이를 분석한 결과, 긴급재난문자의 효과가 작은 지역은 고령인구 비율이 낮은 특징이 있었으며, 고용집적도가 높거나 대중교통 접근성이 높은 특징이 있었다. 이외에도, 사회경제적 특성인 가구원 수, 성비, 평균연령과 물리환경적 특성인 녹지 비율이 지역 간 폭염 긴급재난문자 효과의 격차를 발생시킬 수 있는 것으로 나타났다.

유착성 관절낭염 치료에 있어서 한방 치료와 양방 치료의 임상적 고찰 : 동서협진 모델 개발을 위한 기초 연구를 중심으로

남동우,정인태,김주희,박유선,임사비나,이두익,이재동,이윤호,최도영 경희대학교 동서의학연구소 2006 東西醫學硏究所 論文集 Vol.2006 No.-

Objectives : To observe the effect of acupuncture treatment and western medical treatment on frozen shoulder patients. Methods : 39 voluntary patients were randomly assigned to the Eastern treatment group(E group, n=22) and the Western treatment group(W group, n=17). The E group received acupuncture treatment on LI15, TE14, GB21 and Master Dong's acupuncture points, Shin-gwan and Gyun-joong, twice a week for 4 weeks. The W group received suprascapular nerve block, subacromial injection and trigger point injection, twice a week for 4 weeks. Both groups were instructed to practice self exercise during their daily lives. Evaluations were made before treatment and after treatment using Constant Shoulder Assessment(CSA), Shoulder Pain and Disability Index(SPADI) and the patient's satisfaction concerning the treatment was measured by Visual Analogue Scale(VAS). The obtained data were analyzed and compared. Results : The E group showed significant improvement(p<0.05) according to the CSA and SPADI. The patient's satisfaction scored 5.67 on a scale of 10. The W group showed significant improvement(p<0.05) according to the CSA and SPADI. The patient's satisfaction scored 7.73. But the difference between the two groups were insignificant according to CSA and SPADI. Conclusion : Both acupuncture and nerve block treatment significantly improved frozen shoulder. But the difference of the two treatments was insignificant.

가축분뇨를 이용한 SCP 생산 균주의 분리 및 균체 단백질 생산

한석균,고유석,안태영,배동훈 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

질소원으로서 계분을 이용하는 균주를 선별하고 계분배지에서 균체의 생육속도가 다른 균주에 비하여 우수한 균주를 분리하였다. 형태·생리학적 특성을 기초로 하여 yeast의 분류 기준과 비교하여 본 균주를 Candida sp.로 동정하였으며 본 균주를 Candida sp. D116으로 명명하였다. Poultry feces extract medium에서 4% 농도의 glucose 첨가가 균체 생육에 효과적이었다. D116 균주를 액체 발효하여 균체생산능, 요산 그리고 가용성 단백질의 변화를 조사하였다. 그 결과 약 60시간이 경과하면 액체 발효 배지내의 거의 모든 가용성 단백질 및 요산의 감소를 보였으며 균체생육은 약 36시간 배양하였을 때 최고조에 도달하였고 그 후에는 점차 감소하는 경향을 보였다. SCP의 대량생산의 결과 50%의 계분혼합 배지와 30℃의 배양 온도에서 36시간 배양하여 균주의 생육수준이 3.8×10^9 CFU/ml 농도의 균체를 생산하였고 200 L의 배양액중 약 870 g-dw의 균체를 얻었으며 생산된 군체의 조단백질 함량은 67%이었다. Production of Single Cell Protein from Poultry Feces. Suk-kyun Han, You-Suk Go, Tae-Young Ahn and Dong-Hoon Bal^1*. Deparment of Microbioligy, College of Natural Sciences, Dankook Univerity, Cheonan 330-714 and Research Center for Molecular Microbiology, Seoul Nationa University, Seoul 151-742, Korea, ^1Department of Food Engineering. College of Engineering, Dankook University, Cheonan 330-714 and Bioproducts Research Center of Yonsei University, Seoul 120-749, Korea - From the soil collected form provincial area of South Korea, a microorganisms which have been shown good growth in the minimal poultry feces extract medium was isolated. Supplement of glucose to the poultry feces extract medium helped the complete degraded during the microbial growth. Maximum cell growth (3.8×10^9 CFU/ml) obtained at 36 hours of incubation after inoculation. Uric acid was degraded faster in minimal medium that in the glucose complement medium. VFA (volatile fatty acid), which are known as major compounds of poultry feces odor, were almost removed from the minimal poultry feces extract medium. Glucose supplement to the minimal medium enhanced the growth of microbial cells. Addition of 4% of glucose and 4% of neopeptone to the minimal poultry feces extract medium helped the maximal growth of cells.

경두개방사선사진에서의 하악과두 위치와 관절원판 위치간의 상호관계

유동수,최순철,고재희 大韓口腔顎顔面 放射線學會 1995 Imaging Science in Dentistry Vol.25 No.2

This study was designed to evaluate the interrelationship between the condylar head position in transcranial view and the articular disc position in the arthrography. The condylar positions were assessed by subjective method and linear measurement method on the transcranial view. The subjects for this study consisted of 24 symptomatic joints with normal disc position, 37 joints with anterior disc displacement with reduction and 44 joints with anterior disc displacement without reduction that were classified by arthrotomography under the fluoroscopic guidance. The interrelationship between the condylar head position in transcranial view and the articular disc position in the arthrography was evaluated by Chi square test. The obtained results were as follows : 1. There was no significant interrelationship between the position of condylar head in closed mouth state on transcranial view and articular disc position in the arthrography (p>0.05). 2. There was no significant interrelationship between the changes of interarticular distance in 1 inch opening state and articular disc position in the arthrography (p>0.05). 3. There was no significant interrelationship between the position of condylar head related to the apex of articular eminence in 1 inch opening state and articular disc position in the arthrography (p>0.05). 4. There was significant interrelationship between the changes of interarticular distance that is assessed by linear measurement method in maximum opening state and articular disc position in the arthrography (p>0.05), but there was no significant interrelationship when the condylar head position was assessed by subjective method(p>0.05). 5. There was significant interrelationship between the degree of condylar translation in maximum opening state and articular disc position in the arthrography(p<0.01). 6. The correlation coefficient between two methods to assess the position of condylar head were 0.7989: the condylar head position in articular fossa in closed state, 0.6847: interarticular space in 1 inch opening state, 0.8965: the degree of condylar translation in 1 inch opening state, 0.5944: the changes of interarticular space in maximum opening state, 0.9215: the degree of condylar translation in maximum opening state.

회전변위와 천공을 포함한 측두하악관절 내장증 상태와 임상적 특징간의 상호관계

유동수,정환석 大韓口腔顎顔面 放射線學會 1998 Imaging Science in Dentistry Vol.28 No.1

This study was designed to reveal the correlationship between the internal derangement state of TMJ and clinical characteristics including pain and mandibular dysfunction. One hundred and twenty five subjects with TMJ signs and symptoms were chosen for two years. The level of pain and madibular dysfunction were evaluated by Visual Analog Scale(VAS) and Craniomandibular Index(CMI). The diagnostic categories of TMJ internal derangement were determined by arthrography and they included normal disc position, anterior disc displacement with reduction(ADDR), rotational disc displacement with reduction(RDDR), anterior disc displacement without reduction(ADDNR), and rotational disc displacement without reduction (RDDNR). Also disc perforation was used as a criteria to divide the diagnostic subgroups. The obtained results were as follows; 1. The patient distribution of each group was 5 in normal disc position(4%), 40 in ADDR(32%), 30 in RDDR(24%), 34 in ADDNR (27%), and 16 in RDDNR(13%). 2. Perforation was observed in 8% of ADDR, 10% of RDDR, 32% of ADDNR, and 19% of RDDNR. 3. CMI of non-reduction group was higher than that of reduction or normal group(p<0.05), but VAS showed no significant difference. 4. CMI of perforation group was higher than that of non-perforation group in reduction group (p<0.05). 5. There were no significant differences of CMI and VAS between anterior disc displacement group and rotational disc displacement group in both reduction and non-reduction group. 6. CMI of RDDNR group was higher than that of RDDR group (p<0.05). 7. There were no significant difference of CMI and VAS between bilateral involvement group and unilateral involvement group(p>0.05).

노인 인구에서 신경인지기능저하와 혈청 지질농도와의 상관성

유영선,최석주,정성수,김지은,윤성욱,전동욱,백준형,박성우,이정구,추일한,김영훈 大韓神經精神醫學會 2008 신경정신의학 Vol.47 No.6

Objectives : In this study, the authors evaluated the correlation between eurocognitive impairments and serum lipids levels among Korean elderly over the age of 65. Methods : A total of 609 elderly individuals participated in this study. Screening for cognitive impairments were carried out using the Mini-Mental Status Examination-Korean version (MMSE-KC). There were 197 subjects above 1.5SD Of MMSE- KC and they were evaluated using the Korean versions of the Consortium to Establish a Registry for Alzheimer's Disease (AD) (CERAD-KC) and Geriatric Depression Scale (GDS-K). Results : There was a correlation between old age/low levels of education and AD (p<0.05, P<0.01). There was an inverse correlation between the serum level of total cholesterol and the word list recognition test scores. The serum levels of LDL cholesterol were inversely correlated with the scores on the constructional praxis test, word list recall test and word list recognition test. Inverse correlations between the serum level of triglyceride and scores on the word list recall test and word list recognition test were also observed. Conclusion : There were inverse correlations between the serum levels of lipids and language/memory function in subjects with AD.

익산시 취학 전 어린이의 중증 유아기 우식증 유병률과 섭식습관

유래관,이광희,라지영,이동진 대한소아치과학회 2007 大韓小兒齒科學會誌 Vol.34 No.3

중학교 영어 교과서 Readability 측정

유경아,김동희,전종호,차경환,손석완 中央大學校 韓國敎育問題硏究所 1996 韓國敎育問題硏究所論文集 Vol.- No.11

The main purpose of this study is to find out whether current English textbooks for middle school students in Korea are properly leveled or graded. The researchers utilized Fry Readability Graph, Flesch Readability Formula, and Dale-Chall Readability Formula for the analysis of eight English textbooks which are being used for second graders. The results of the analysis are as follows. 1. The texts are at least one or two levels higher than the formula suggest. 2. Most of the English textbooks are not properly graded in the light of readability. 3. Dale-Chall's readability formula has more precise prediction about readability analysis among them.